Abstract:
BACKGROUND:The promising results of the Solitaire Flow Restoration (FR) With the Intention for Thrombectomy (SWIFT) trial recently led to Food and Drug Administration (FDA) approval of the Solitaire FR stent retriever device for recanalization of cerebral vessels in patients with acute ischemic stroke. OBJECTIVE:To report the early postmarket experience with this device since its FDA approval in the United States, which has not been previously described. METHODS:We conducted a retrospective analysis of consecutive acute ischemic strokes cases treated between March 2012 and July 2012 at 10 United States centers where the Solitaire FR was used as a single device or in conjunction with other intraarterial endovascular approaches. RESULTS:A total of 101 patients were identified (mean age, 64.7 years; mean admission National Institutes of Health Stroke Scale [NIHSS] score, 17.6). Intravenous thrombolysis was administered in 39% of cases; other endovascular techniques were utilized in conjunction with the Solitaire FR in 52%. Successful recanalization (Thrombolysis in Myocardial Infarction 2/3) was achieved in 88%. The rate of symptomatic intracranial hemorrhage within the first 24 hours was 15%. In-hospital mortality was 26%. At 30 days, 38% of patients had favorable functional outcome (modified Rankin scale score ≤2). Severity of NIHSS score on admission was a strong predictor of poor outcome. CONCLUSION:Our study shows that a variety of other endovascular approaches are used in conjunction with Solitaire FR in actual practice in the United States. Early postmarket results suggest that Solitaire FR is an effective tool for endovascular treatment of acute ischemic stroke.
journal_name
Neurosurgeryjournal_title
Neurosurgeryauthors
Mokin M,Dumont TM,Veznedaroglu E,Binning MJ,Liebman KM,Fessler RD 2nd,To CY,Turner RD 4th,Turk AS,Chaudry MI,Arthur AS,Fox BD,Hanel RA,Tawk RG,Kan P,Gaughen JR Jr,Lanzino G,Lopes DK,Chen M,Moftakhar R,Billingsleydoi
10.1227/01.neu.0000429859.96652.57subject
Has Abstractpub_date
2013-07-01 00:00:00pages
19-25; discussion 25-6issue
1eissn
0148-396Xissn
1524-4040journal_volume
73pub_type
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