Abstract:
:This study investigated the spinal evoked response to focal electrical stimulation of the sensorimotor cortex in 32 rats. The results demonstrate a long-latency response (beginning at 8 milliseconds) elicited by electrical stimulation, which is distinct from the short-latency motor evoked potential previously reported. The conduction velocity of this later response is similar to that reported for the pyramidal tract in the rat. Experiments confirm that the longer latency response depends upon the integrity of the pyramidal system. Focal stimulation outside the sensorimotor cortex failed to elicit a response. Experimental lesions of the pyramidal tract or ablating the sensorimotor cortex eliminated the spinal cord evoked response. The results demonstrate that focal stimulation of the sensorimotor cortex results in a spinal cord evoked response that represents activity within the pyramidal system. The utility of this response in the rat model for assessing experimental cord injury is discussed.
journal_name
Neurosurgeryjournal_title
Neurosurgeryauthors
Ryder J,Zappulla R,Nieves Jdoi
10.1097/00006123-199104000-00011subject
Has Abstractpub_date
1991-04-01 00:00:00pages
550-8issue
4eissn
0148-396Xissn
1524-4040journal_volume
28pub_type
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