Motor evoked potentials elicited from pyramidal stimulation and recorded from the spinal cord in the rat.

Abstract:

:This study investigated the spinal evoked response to focal electrical stimulation of the sensorimotor cortex in 32 rats. The results demonstrate a long-latency response (beginning at 8 milliseconds) elicited by electrical stimulation, which is distinct from the short-latency motor evoked potential previously reported. The conduction velocity of this later response is similar to that reported for the pyramidal tract in the rat. Experiments confirm that the longer latency response depends upon the integrity of the pyramidal system. Focal stimulation outside the sensorimotor cortex failed to elicit a response. Experimental lesions of the pyramidal tract or ablating the sensorimotor cortex eliminated the spinal cord evoked response. The results demonstrate that focal stimulation of the sensorimotor cortex results in a spinal cord evoked response that represents activity within the pyramidal system. The utility of this response in the rat model for assessing experimental cord injury is discussed.

journal_name

Neurosurgery

journal_title

Neurosurgery

authors

Ryder J,Zappulla R,Nieves J

doi

10.1097/00006123-199104000-00011

subject

Has Abstract

pub_date

1991-04-01 00:00:00

pages

550-8

issue

4

eissn

0148-396X

issn

1524-4040

journal_volume

28

pub_type

杂志文章
  • Recurrent cerebellar hemangioblastoma with enhancing tumor in the cyst wall: case report.

    abstract:OBJECTIVE:Hemangioblastomas are the most common primary intra-axial tumors of the adult posterior fossa and the tumors most often associated with von Hippel-Lindau disease. Resection of cerebellar hemangioblastomas involves tumor excision and drainage of associated cysts. The cyst wall is considered devoid of tumor cel...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/01.neu.0000333313.33296.02

    authors: Bishop FS,Liu JK,Chin SS,Fults DW

    更新日期:2008-06-01 00:00:00

  • Somatosensory evoked potential monitoring during endoscopic endonasal approach to skull base surgery: analysis of observed changes.

    abstract:BACKGROUND:Intraoperative neurophysiological monitoring, including upper- and lower-extremity somatosensory evoked potentials (SSEPs), has been used to identify and prevent injury to neurovascular structures during conventional skull base surgery. The expanded endonasal approach (EEA) is a novel minimally invasive appr...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/NEU.0b013e31821606e4

    authors: Thirumala PD,Kassasm AB,Habeych M,Wichman K,Chang YF,Gardner P,Prevedello D,Snyderman C,Carrau R,Crammond DJ,Balzer J

    更新日期:2011-09-01 00:00:00

  • Endovascular recanalization with balloon angioplasty and stenting of an occluded occipital sinus for treatment of intracranial venous hypertension: technical case report.

    abstract:OBJECTIVE AND IMPORTANCE:Dural sinus thrombosis can lead to intracranial venous hypertension and can be complicated by intracranial hemorrhage. We present a case report of a patient who underwent endovascular recanalization and stenting of a thrombosed occipital sinus. CLINICAL PRESENTATION:A 13-year-old patient with ...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1097/00006123-199904000-00133

    authors: Malek AM,Higashida RT,Balousek PA,Phatouros CC,Smith WS,Dowd CF,Halbach VV

    更新日期:1999-04-01 00:00:00

  • iPod touch-assisted instrumentation of the spine: a technical report.

    abstract:BACKGROUND:Instrumentation of the spine depends on choosing the correct insertion angles to implant screws. Although modern image guidance facilitates precise instrumentation of the spine, the equipment is costly and availability is limited. Although most surgeons use lateral fluoroscopy to guide instrumentation in the...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/NEU.0000000000000023

    authors: Jost GF,Bisson EF,Schmidt MH

    更新日期:2013-12-01 00:00:00

  • Recurrent spontaneous spinal cerebrospinal fluid leak associated with "nude nerve root" syndrome: case report.

    abstract:OBJECTIVE AND IMPORTANCE:Spontaneous spinal cerebrospinal fluid (CSF) leaks have been noted occasionally at multiple sites in the same patient, but recurrent spontaneous spinal CSF leaks have not been documented. We describe a patient with a recurrent CSF leak who was found at surgery to have an absence of the entire n...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/01.neu.0000089483.30857.11

    authors: Schievink WI,Jacques L

    更新日期:2003-11-01 00:00:00

  • Surgical approaches for the correction of metopic synostosis.

    abstract::Premature closure of the metopic suture results in a deformity ranging from a minor variation to a severe cosmetic deformity. The three principal abnormalities comprising metopic synostosis are trigonocephaly secondary to the restriction of growth of both frontal bones, deficient lateral supraorbital rims, and hypotel...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198608000-00008

    authors: Delashaw JB,Persing JA,Park TS,Jane JA

    更新日期:1986-08-01 00:00:00

  • Clinical and Short-Term Radiographic Outcomes of Minimally Invasive Transforaminal Lumbar Interbody Fusion With Expandable Lordotic Devices.

    abstract:BACKGROUND:Minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) is a well-accepted procedure for the treatment of degenerative lumbar disease. However, its ability to restore lumbar lordosis has been limited. Development of expandable lordotic interbody devices has challenged this limitation, furthering...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1093/neuros/nyz402

    authors: McMordie JH,Schmidt KP,Gard AP,Gillis CC

    更新日期:2020-02-01 00:00:00

  • Ethylene oxide sterilization of bone, dura mater, and fascia lata for human transplantation.

    abstract::The use of allogeneic human bone, dura, and fascia has achieved an enduring and accelerating role in the augmentation of spinal fusions and the repair of skeletal and dural defects. Primary sterilization of these nonviable cadaveric tissues magnifies the potential sources and ensures the microbiological sterility of t...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198005000-00006

    authors: Prolo DJ,Pedrotti PW,White DH

    更新日期:1980-05-01 00:00:00

  • An alternative ultrasonographic approach to assess basilar artery flow.

    abstract:BACKGROUND:Assessment of basilar artery blood flow is of interest in many neurosurgical situations. With use of ultrasonography, the standard posterior approach is difficult in neurointensive care. OBJECTIVE:To evaluate the accuracy of an alternative submandibular approach for the assessment of blood flow in the basil...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/NEU.0b013e3182124835

    authors: Geeraerts T,Thome W,Tanaka S,Leblanc PE,Duranteau J,Vigué B

    更新日期:2011-06-01 00:00:00

  • Comparison of laser and radiofrequency dorsal root entry zone lesions in cats.

    abstract::Dorsal root entry zone lesions are effective in the control of intractable pain in several types of spinal cord injuries. Traditionally, these lesions have been made with the radiofrequency technique. This is effective, but has the drawback of being laborious, and there is a significant incidence of permanent weakness...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198503000-00008

    authors: Levy WJ,Gallo C,Watts C

    更新日期:1985-03-01 00:00:00

  • Spinal cord compression: a complication of silicone-coated Dacron dural grafts. Report of two cases.

    abstract::Two case reports of compression of the cervical spinal cord associated with silicone-coated Dacron dural grafts are presented. In both cases, the cervical spinal cord was distorted and compressed by an intense tissue reaction that encapsulated the synthetic graft. At least two factors are thought to play a role in pre...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198901000-00022

    authors: Gomez H,Little JR

    更新日期:1989-01-01 00:00:00

  • Effect of osmotic blood-brain barrier disruption on methotrexate pharmacokinetics in the dog.

    abstract::Infusion of 25% mannitol into the internal carotid artery of the dog results in a reversible disruption of the blood-brain barrier (BBB). This osmotic BBB disruption enhances the penetratin of systemically administered methotrexate (MTX) into the ipsilateral cerebral hemisphere. Brain methotexate levels were maximized...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198007000-00006

    authors: Neuwelt EA,Frenkel EP,Rapoport S,Barnett P

    更新日期:1980-07-01 00:00:00

  • Anatomical study of the superficial temporal artery.

    abstract::Fifty consecutive human autopsy specimens were studied to determine the suitability of the superficial temporal artery (STA) for use in microvascular anastomoses. Ten variations of the STA were found. The STA at the zygoma averaged 2.2 mm in outside diameter. The STA averaged 31.7 mm from the zygoma to its bifurcation...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198506000-00008

    authors: Marano SR,Fischer DW,Gaines C,Sonntag VK

    更新日期:1985-06-01 00:00:00

  • Anatomy of the superior ophthalmic vein approach for direct endovascular access to vascular lesions of the orbit and cavernous sinus.

    abstract:OBJECTIVE:The superior ophthalmic vein (SOV) provides an alternative venous access for the treatment of carotid-cavernous fistulae. Its direct surgical exposure and cannulation can be difficult. This study was performed to identify anatomic landmarks to facilitate localization and exposure of the SOV. METHODS:The vasc...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/01.NEU.0000340781.34122.A2

    authors: Reis CV,Gonzalez FL,Zabramski JM,Hassan A,Deshmukh P,Albuquerque FC,Preul MC

    更新日期:2009-05-01 00:00:00

  • A new, more accurate classification of middle cerebral artery aneurysms: computed tomography angiographic study of 1,009 consecutive cases with 1,309 middle cerebral artery aneurysms.

    abstract:BACKGROUND:Classification of middle cerebral artery (MCA) aneurysms is sometimes difficult because the identification of the main MCA bifurcation, the key for accurate classification of MCA aneurysms, is inconsistent and somewhat subjective. OBJECTIVE:To use the meeting point of the M1 and M2 trunks as an objective, g...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/01.neu.0000429842.61213.d5

    authors: Elsharkawy A,Lehečka M,Niemelä M,Billon-Grand R,Lehto H,Kivisaari R,Hernesniemi J

    更新日期:2013-07-01 00:00:00

  • Three-dimensional computed tomographic cranial base measurements for improvement of surgical approaches to the petrous carotid artery and apex regions.

    abstract:OBJECTIVE:The bony and vascular anatomic features in the region of the petrous apex can vary significantly. These variations affect the operative view obtained via extended subtemporal or anterior transpetrosal approaches to cranial base lesions for individual patients. The goal of this study was to evaluate three-dime...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1097/00006123-200108000-00016

    authors: Villavicencio AT,Leveque JC,Bulsara KR,Friedman AH,Gray L

    更新日期:2001-08-01 00:00:00

  • Occipital sinus pericranii superseding both jugular veins: description of two rare pediatric cases.

    abstract:BACKGROUND AND IMPORTANCE:The extracranial venous drainage of the brain is provided mainly by the jugular veins with the variable participation of extrajugular pathways. CLINICAL PRESENTATION:Two cases of occipital sinus pericranii (SP) were observed. A 6-year-old girl presented with a progressively enlarging occipita...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/NEU.0b013e31828baab4

    authors: Frassanito P,Massimi L,Tamburrini G,Caldarelli M,Pedicelli A,Di Rocco C

    更新日期:2013-06-01 00:00:00

  • The simplified acute physiology score to predict outcome in patients with subarachnoid hemorrhage.

    abstract:OBJECTIVE:Current prognosticators for patients with subarachnoid hemorrhage (SAH) do not take into account signs of extracerebral organ dysfunction. This may explain the only moderate predictive value of these prognosticators. We assessed the prognostic value of the simplified acute physiology score (SAPS) II in SAH pa...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/01.neu.0000166536.42876.9c

    authors: Schuiling WJ,de Weerd AW,Dennesen PJ,Algra A,Rinkel GJ

    更新日期:2005-08-01 00:00:00

  • Familial cerebral aneurysms: a study of 13 families.

    abstract::Despite the recent interest in familial cerebral aneurysms, the epidemiology, natural history, pattern of inheritance, screening of asymptomatic relatives, and the search for a biochemical marker remain problematic. To assess these issues, we report the results of our prospective study of 30 patients with 38 aneurysms...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-199510000-00005

    authors: Leblanc R,Melanson D,Tampieri D,Guttmann RD

    更新日期:1995-10-01 00:00:00

  • Neuro-ophthalmic complications of intracranial catheters.

    abstract::We report four patients who sustained direct injury to the brain after insertion of intraventricular shunts and pressure monitoring lines, which resulted in permanent neuro-ophthalmic deficits. These included hemianopsia from an optic tract lesion, esotropia and residual bilateral facial paresis from dorsal pontine in...

    journal_title:Neurosurgery

    pub_type: 杂志文章,评审

    doi:10.1227/00006123-199307000-00022

    authors: Shults WT,Hamby S,Corbett JJ,Kardon R,Winterkorn JS,Odel JG

    更新日期:1993-07-01 00:00:00

  • Techniques of spinal cord surgery in fetal rats.

    abstract::These experiments were done to develop techniques to expose and manipulate the spinal cord in fetal rats, techniques that could be used to study spinal cord regeneration and transplantation. Adequate maternal anesthesia required a mixture of acepromazine-ketamine supplemented by thiopental. Fetal rats were operated on...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198702000-00007

    authors: Albright L

    更新日期:1987-02-01 00:00:00

  • Esophageal perforation during surgery on the cervical spine.

    abstract::Esophageal perforation during surgery for cervical disc herniation is a rare complication. Differences in the time of diagnosis of this complication in three patients--no delay and delays of 6 hours and 4 days, respectively--resulted in different symptoms and outcomes. Early detection of the perforation allows prompt ...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1097/00006123-199111000-00021

    authors: van Berge Henegouwen DP,Roukema JA,de Nie JC,vd Werken C

    更新日期:1991-11-01 00:00:00

  • Higher cortical disorders: an unusual presentation of an arteriovenous malformation.

    abstract::The authors present a patient with a large arteriovenous malformation in the temperoparietooccipital region of the dominant hemisphere that caused seizures, a homonymous hemianopia, and broad neuropsychological disturbances probably caused by a cerebral steal syndrome. There was no history of hemorrhage. Surgical rese...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198712000-00009

    authors: von Overbeeke JJ,Bosma NJ,Verdonck AF,von Huffelen AC

    更新日期:1987-12-01 00:00:00

  • Elevation of brain norepinephrine concentration after experimental subarachnoid hemorrhage.

    abstract::Regional brain tissue catecholamine concentrations were measured in 5 control rats and in 10 rats 72 hours after experimental subarachnoid hemorrhage (SAH). Catecholamine levels were determined in the cerebral hemispheres, brain stem, and cerebellum of each animal using a radioenzymatic assay. Three days after SAH, th...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198609000-00005

    authors: Solomon RA,McCormack BM,Lovitz RN,Swift DM,Hegemann MT

    更新日期:1986-09-01 00:00:00

  • Determination of the minimum improvement in pain, disability, and health state associated with cost-effectiveness: introduction of the concept of minimum cost-effective difference.

    abstract:BACKGROUND:Minimum clinical important difference (MCID) has been adopted as the smallest improvement in patient-reported outcome needed to achieve a level of improvement thought to be meaningful to patients. OBJECTIVE:To use a common MCID calculation method with a cost-utility threshold anchor to introduce the concept...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/01.neu.0000462079.96571.dc

    authors: Parker SL,McGirt MJ

    更新日期:2015-03-01 00:00:00

  • Technique, Results, and Complications Related to Robot-Assisted Stereoelectroencephalography.

    abstract:BACKGROUND:Robot-assisted stereoelectroencephalography (SEEG) may represent a simplified, precise, and safe alternative to the more traditional SEEG techniques. OBJECTIVE:To report our clinical experience with robotic SEEG implantation and to define its utility in the management of patients with medically refractory e...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/NEU.0000000000001034

    authors: González-Martínez J,Bulacio J,Thompson S,Gale J,Smithason S,Najm I,Bingaman W

    更新日期:2016-02-01 00:00:00

  • Endolymphatic sac tumors: report of three cases.

    abstract:OBJECTIVE AND IMPORTANCE:We present three cases of endolymphatic sac tumors and review the previously published cases. Despite frequent extension to the cerebellopontine angle, these rare tumors have only recently been recognized by neurosurgeons. CLINICAL PRESENTATION:A 26-year-old man developed a progressive hearing...

    journal_title:Neurosurgery

    pub_type: 杂志文章,评审

    doi:10.1097/00006123-199804000-00139

    authors: Roche PH,Dufour H,Figarella-Branger D,Pellet W

    更新日期:1998-04-01 00:00:00

  • Expression of endothelial cell angiogenesis receptors in human cerebrovascular malformations.

    abstract:OBJECTIVE:To further understand the role of angiogenic growth factors in the development of cerebral cavernous malformations (CCMs) and arteriovenous malformations (AVMs), we investigated endothelial cell (EC) expression of receptors for vascular endothelial growth factor (VEGF) and angiopoietin systems in patients wit...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1097/00006123-200102000-00024

    authors: Uranishi R,Baev NI,Ng PY,Kim JH,Awad IA

    更新日期:2001-02-01 00:00:00

  • Contralateral pterional approach to a giant internal carotid-ophthalmic artery aneruysm: technical case report.

    abstract:OBJECTIVE AND IMPORTANCE:The contralateral approach to internal carotid-ophthalmic artery aneurysms has been used in selected cases but has rarely been described for a giant internal carotid artery aneurysm. We report a case of giant aneurysm that was successfully clipped via the contralateral pterional approach. CLIN...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1097/00006123-200104000-00059

    authors: Hongo K,Watanabe N,Matsushima N,Kobayashi S

    更新日期:2001-04-01 00:00:00

  • Stereotactic radiosurgery for cavernous malformations: Kjellberg's experience with proton beam therapy in 98 cases at the Harvard Cyclotron.

    abstract:OBJECTIVE:The lack of treatment options for surgically inaccessible cavernous malformations has made radiosurgery a possible alternative to conservative management. The few previous reports of radiosurgical efficacy have been limited by small numbers, short follow-up, or lack of attention to the full spectrum of end po...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1097/00006123-199806000-00013

    authors: Amin-Hanjani S,Ogilvy CS,Candia GJ,Lyons S,Chapman PH

    更新日期:1998-06-01 00:00:00