Marinosomes, marine lipid-based liposomes: physical characterization and potential application in cosmetics.

Abstract:

:Marinosomes are liposomes based on a natural marine lipid extract containing a high polyunsaturated fatty acid (PUFA) ratio. They were prepared and characterized in conditions that mimic that of topical application in terms of pH, temperature and calcium. Marinosomes were stable in storage conditions for 1 month. At low pH (pH 4) or in presence of high calcium concentrations (9 mM), complex structural rearrangements, such as aggregation and size reduction, occurred which were kinetically dependant.

journal_name

Int J Pharm

authors

Moussaoui N,Cansell M,Denizot A

doi

10.1016/s0378-5173(02)00217-x

keywords:

subject

Has Abstract

pub_date

2002-08-21 00:00:00

pages

361-5

issue

1-2

eissn

0378-5173

issn

1873-3476

pii

S037851730200217X

journal_volume

242

pub_type

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