Abstract:
:Marinosomes are liposomes based on a natural marine lipid extract containing a high polyunsaturated fatty acid (PUFA) ratio. They were prepared and characterized in conditions that mimic that of topical application in terms of pH, temperature and calcium. Marinosomes were stable in storage conditions for 1 month. At low pH (pH 4) or in presence of high calcium concentrations (9 mM), complex structural rearrangements, such as aggregation and size reduction, occurred which were kinetically dependant.
journal_name
Int J Pharmjournal_title
International journal of pharmaceuticsauthors
Moussaoui N,Cansell M,Denizot Adoi
10.1016/s0378-5173(02)00217-xkeywords:
subject
Has Abstractpub_date
2002-08-21 00:00:00pages
361-5issue
1-2eissn
0378-5173issn
1873-3476pii
S037851730200217Xjournal_volume
242pub_type
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