Abstract:
:The aim of this study was to determine the efficacy and safety of intrathecal baclofen therapy delivered by a programmable pump for the chronic treatment of spinal spasticity. Twelve patients with intractable spasticity caused by spinal cord injuries underwent implantation of a programmable continuous infusion pump after significant reduction in spasticity following an intrathecal test bolus of baclofen. No deaths or new permanent neurological deficits occurred following surgery or chronic intrathecal baclofen therapy. The follow-up (12 months) shows a reduction in rigidity in the lower limb of 2.0 points on the Ashworth scale and in the upper limb of 1.2 points. Muscle spasms were reduced from a mean preoperative score of 2.8 to a mean postoperative score of 1.0. In two cases, we observed postoperative catheter dislocation, a complication which could be corrected surgically. This study demonstrates that chronic intrathecal baclofen infusion is a safe and effective form of treatment of intractable spasticity in patients with spinal cord injury. There is considerable reduction in the risk of infection in view of the fact that interrogation and programming of the implanted programmed pumps is noninvasive.
journal_name
Neurosurg Revjournal_title
Neurosurgical reviewauthors
Korenkov AI,Niendorf WR,Darwish N,Glaeser E,Gaab MRdoi
10.1007/s10143-002-0221-1keywords:
subject
Has Abstractpub_date
2002-08-01 00:00:00pages
228-30issue
4eissn
0344-5607issn
1437-2320journal_volume
25pub_type
杂志文章abstract::Surgical resections of meningiomas, the most common intracranial tumor in adults, can only be curative if radical resection is achieved. Potentially, the extent of resection could be improved, especially in complex and/or high-grade meningiomas by fluorescence-guided surgery using 5-aminolevulinic acid (5-ALA), indocy...
journal_title:Neurosurgical review
pub_type: 杂志文章,评审
doi:10.1007/s10143-018-01062-4
更新日期:2019-12-01 00:00:00
abstract::Growing evidence from recent studies have revealed that long non-coding RNA (lncRNA) might be a useful prognostic biomarker for glioma; we therefore conducted the current meta-analysis to evaluate prognostic and clinicopathological predictive value of lncRNA expression for glioma patients. Eligible studies were identi...
journal_title:Neurosurgical review
pub_type: 杂志文章,meta分析
doi:10.1007/s10143-018-0965-x
更新日期:2020-02-01 00:00:00
abstract::Digital subtraction angiography (DSA) is the preferred method for confirming dural arteriovenous fistulas (DAVFs), but it has the disadvantage of being invasive. In contrast, time-resolved magnetic resonance angiography (TR-MRA) is a useful, noninvasive imaging technique. The aim of this study was to compare the evalu...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-010-0246-9
更新日期:2010-04-01 00:00:00
abstract::Teflon is utilized in neurosurgery as well as in plastic, vascular and heart surgery. Although the effect of Teflon on different types of cells and tissues has been previously studied, we are not aware of any study in which the effect of Teflon was tested on cells of the central nervous system. We have therefore exami...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/BF00346368
更新日期:1990-01-01 00:00:00
abstract::An embryological association between moyamoya disease (MMD) and cardiac manifestations has been proposed. Data up to this point remains anecdotal, and the prevalence of cardiac manifestations in a western MMD population is uncertain. The objective of this study was to determine the prevalence of cardiac manifestations...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-020-01327-x
更新日期:2020-06-07 00:00:00
abstract::In neurosurgical operations, proper craniotomy using retractors is necessary. Various surgical instruments are used for this purpose, including standard retractors and multipurpose head frame retractor systems. However, the conventional multipurpose head frame system is often not optimal for use in some craniotomies a...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-020-01237-y
更新日期:2020-01-11 00:00:00
abstract::Superficial temporal artery-middle cerebral artery (STA-MCA) anastomosis is a safe and effective treatment for moyamoya disease, although recent evidence suggests its substantial risk for symptomatic cerebral hyperperfusion. The diagnostic value of single-photon emission computed tomography (SPECT) for postoperative h...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-008-0147-3
更新日期:2008-10-01 00:00:00
abstract::Paraffin-embedded surgical specimens from 55 meningiomas were immunostained after microwave processing using the streptavidin/peroxidase method and the monoclonal antibody (moAb) MIB-1 to the Ki-67 antigen. The authors assessed proliferative labelling index (LI) from a series of surgically removed meningiomas using im...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-003-0261-1
更新日期:2003-07-01 00:00:00
abstract::Intradiploic epidermoid tumor of the occipital bone was presented. There were neither intracranial extensions nor neurologic deficits. The lesion started as a painless mass under the scalp. The total removal of the tumor was associated with a good prognosis. ...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/BF00418080
更新日期:1996-01-01 00:00:00
abstract::Despite the introduction of new antiepileptic drugs and advances in the surgical treatment of epilepsy, an important group of patients still remains uncontrolled by any of these methods. The relatively recent introduction of vagus nerve stimulation is yet another possible treatment for refractory epilepsy. This safe, ...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-014-0555-5
更新日期:2014-10-01 00:00:00
abstract::Craniopharyngiomas (CPs) are rare, benign tumors derived from Rathke's pouch, known for their high recurrence rates and associated morbidity and mortality. Despite significant investigation on risk factors for recurrence, a lack of consensus persists. Recent research suggests that specific histopathological and molecu...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-018-0978-5
更新日期:2020-02-01 00:00:00
abstract::Histological, immunocytochemical, and biological features of 38 giant cell gliomas were investigated. The invasion of these tumors and its giant cells by histiocytes, lymphocytes, plasma cells, and especially by eosinophilic granulocytes is viewed as an immune response, which may explain a favorable clinical course. F...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/BF01782050
更新日期:1987-01-01 00:00:00
abstract::Cerebral infarction (CI) associated with clipping of unruptured intracranial aneurysms (UIAs) has not been completely studied. The role of individual and operative characteristics is not known, and the risk of silent CI has not been well described. To determine the incidence, risk factors, and clinical outcome of post...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-017-0913-1
更新日期:2018-04-01 00:00:00
abstract::The authors describe 3 cases of cerebral pleomorphic xanthoastrocytoma, one of which has an unusual neuroradiological appearance, and review the clinical and prognostic features of the 96 cases reported in the literature. Pleomorphic xanthoastrocytoma is a neuroectodermal tumor that affects young patients, in a superf...
journal_title:Neurosurgical review
pub_type: 杂志文章,评审
doi:10.1007/BF00346603
更新日期:1996-01-01 00:00:00
abstract::The purpose of this paper is to provide a comprehensive review encompassing the syndromes associated with the lower cranial nerves (LCNs). We will discuss the anatomy of some of these syndromes and the historical contributors after whom they were named. The LCNs can be affected individually or in combination, since th...
journal_title:Neurosurgical review
pub_type: 杂志文章,评审
doi:10.1007/s10143-020-01344-w
更新日期:2020-07-08 00:00:00
abstract::A hypothalamic hamartoma associated with true precocious puberty in a 7-month-old girl is hereby reported. Hormonal studies disclosed elevated serum levels of luteinizing hormone (LH) and follicle stimulating hormone, both of which responded well to LH-releasing hormone stimulation. Following a subtotal removal of the...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/BF00258250
更新日期:1993-01-01 00:00:00
abstract::The vasodilatory calcitonin gene-related peptide (CGRP) is excessively released after spontaneous subarachnoid hemorrhage (sSAH) and modulates psycho-behavioral function. In this pilot study, we prospectively analyzed the treatment-specific differences in the secretion of endogenous CGRP into cerebrospinal fluid (CSF)...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-020-01333-z
更新日期:2020-06-22 00:00:00
abstract::Clinical practice guidelines (CPGs) play an important role in healthcare. The guideline development process should be precise and rigorous to ensure that the results are reproducible and not vague. To determine the quality of guidelines, the Appraisal of Guidelines and Research and Evaluation (AGREE) instrument was de...
journal_title:Neurosurgical review
pub_type: 杂志文章,评审
doi:10.1007/s10143-014-0569-z
更新日期:2015-01-01 00:00:00
abstract::Among 1142 patients with head injuries hospitalized in the Neurosurgery Department of Gazi University Medical School during the period between 1979 and 1992, 583 had initial CT scans. A retrospective analysis of these initial CT images revealed intracranial air on admission in only 21 cases. These were classified as a...
journal_title:Neurosurgical review
pub_type: 临床试验,杂志文章
doi:10.1007/BF01111479
更新日期:1998-01-01 00:00:00
abstract::Esthesioneuroblastoma is an uncommon malignant neoplasm that arises from olfactory mucosa, often with intracranial extension. A case report of the youngest victim in the literature (2-year-old boy) is presented. ...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/BF01390528
更新日期:1997-01-01 00:00:00
abstract::The posteroinferior region of the thalamus is formed by the pulvinar, and it is surgically accessed through the infratentorial supracerebellar approach, between the midline and the retromastoid region. This study aimed to compare the paramedian, lateral, extreme lateral, and contralateral paramedian corridors with the...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-020-01405-0
更新日期:2020-10-24 00:00:00
abstract::Endoscopy in cerebellopontine angle surgery is an increasingly used technique. Despite of its advantages, the shortcomings arising from the complex anatomy of the posterior fossa are still preventing its widespread use. To overcome these drawbacks, the goal of this study was to define the anatomy of different endoscop...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-016-0800-1
更新日期:2017-07-01 00:00:00
abstract::Massive hemorrhage is a very uncommon event among hemangioblastomas. Forty-four cases have been reported before this review. Thorough analysis of all reported cases on literature was accomplished. The majority presented as parenchymatous or subarachnoid bleedings. Subarachnoid hemorrhage was only associated with spina...
journal_title:Neurosurgical review
pub_type: 杂志文章,评审
doi:10.1007/s10143-009-0217-1
更新日期:2010-01-01 00:00:00
abstract::As a result of their presumed benign natural history, cerebral capillary telangiectasias (CCTs) are infrequently addressed in the neurosurgical literature. We performed a comprehensive review of CCTs via the PubMed database to synthesize overall epidemiological, radiographic, natural history, and treatment results. Ac...
journal_title:Neurosurgical review
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s10143-012-0435-9
更新日期:2013-04-01 00:00:00
abstract::Excision of a circumscribed spongioblastoma with intrapontine-intramesencephalic extension was performed via the floor of the fourth ventricle in two girls 14 and 5 years of age. The preoperative neurological deficits (severe hemiparesis, cerebellar, and sixth and seventh cranial nerve disturbances) showed slow but co...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/BF01743035
更新日期:1983-01-01 00:00:00
abstract::The spatial complexity of highly vulnerable structures makes surgical resection of brainstem cavernomas (BSC) a challenging procedure. Diffusion tensor imaging (DTI) allows for the visualization of white matter tracts and enables a better understanding of the anatomical location of corticospinal and sensory tracts bef...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-014-0550-x
更新日期:2014-07-01 00:00:00
abstract::We present 78 patients with spinal cord injuries. Operation is not indicated in cord contusion, extended bleeding into the spinal canal or severe fracture dislocation. However, it would seem advisable to operate on patients with vertebral fractures, particularly at the lower thoracic and lumbar levels, if intraspinal ...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/BF01790702
更新日期:1989-01-01 00:00:00
abstract::The pattern of hormone secretion by human pituitary tumours in cell or explant culture has been shown to be of value in establishing the nature of the tissue. There was complete agreement between the diagnosis reached by conventional immunocytochemical techniques and by examining the secretion of hormones in culture. ...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/BF01815438
更新日期:1985-01-01 00:00:00
abstract::Experimental brain tumours were produced in cats by stereotactic implantation of 4 million suspended cells of a rat glioma clone into the internal capsule. Three weeks after implantation a spherical tumour developed with a diameter of up to 10 mm which was surrounded by vasogenic white matter oedema. In untreated anim...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/BF01743708
更新日期:1981-01-01 00:00:00
abstract::Hemorrhagic complication is one of the notable surgical complications of the revascularization surgery for moyamoya disease (MMD). Cerebral hyperperfusion (CHP) has been considered as the underlying cause of this complication. It mostly occurs several days after surgery, but the intra-operative hemorrhage immediately ...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-017-0868-2
更新日期:2017-10-01 00:00:00