Abstract:
:Paraffin-embedded surgical specimens from 55 meningiomas were immunostained after microwave processing using the streptavidin/peroxidase method and the monoclonal antibody (moAb) MIB-1 to the Ki-67 antigen. The authors assessed proliferative labelling index (LI) from a series of surgically removed meningiomas using immunohistochemical methods and MIB-1, and they correlated this index with clinical, radiological, and histological factors. No relationship was found between LI, sex, age, resection and histological grades, or volume. Symptoms, location, and peritumoural oedema did have a significant relationship to the MIB-1 LI. The symptomatic patients, i.e. those with tumours at the base of the skull and with GR3 peritumoural oedema (grade 3), had a greater chance of higher MIB-1 LI. It was proven that the increase of one unit in peritumoural oedema classification gave an increased risk of 3.312 and an LI greater than 3%. The authors also discuss the different methods of evaluating LIs in meningiomas, based on the available literature.
journal_name
Neurosurg Revjournal_title
Neurosurgical reviewauthors
Aguiar PH,Tsanaclis AM,Tella OI Jr,Plese JPdoi
10.1007/s10143-003-0261-1keywords:
subject
Has Abstractpub_date
2003-07-01 00:00:00pages
221-8issue
3eissn
0344-5607issn
1437-2320journal_volume
26pub_type
杂志文章abstract::A retrospective clinical study was made on 987 patients with lumbar disc disease treated by discectomy. All patients had been operated on in the Department of Neurosurgery (University-Hospital Mainz). 545 patients were males, and 442 females (1.2:1). Patients in the 4th decade of life were affected most often (33.5%)....
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/BF00313019
更新日期:1990-01-01 00:00:00
abstract::There are still different descriptions of the segmentation of the posterior cerebral artery, although there is a radiological and anatomical consensus on the segmentation of the anterior and the middle cerebral artery. This study aims to define the most appropriate localization for origin and end points of the segment...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-018-0972-y
更新日期:2019-03-01 00:00:00
abstract::Hemodynamic parameters play a significant role in the development of cerebral aneurysms. Parameters such as wall shear stress (WSS) or velocity could change in time and may contribute to aneurysm growth and rupture. However, the hemodynamic changes at the rupture location remain unclear because it is difficult to obta...
journal_title:Neurosurgical review
pub_type: 杂志文章,评审
doi:10.1007/s10143-016-0795-7
更新日期:2017-04-01 00:00:00
abstract::Acute management of deep-seated hematomas remains controversial. Since patients with these hematoma later tend to develop severe edema and necrosis around the lesion, when surgery is indicated it should be done as early as possible. The purpose of this study was to compare whether early surgical removal and conservati...
journal_title:Neurosurgical review
pub_type: 临床试验,杂志文章
doi:10.1007/pl00012391
更新日期:2001-07-01 00:00:00
abstract::Sinus pericranii is a rare vascular abnormality characterised by abnormal connections between the intra- and extracranial venous systems and is usually found in children. In most instances, a sinus pericranii presents as a soft scalp swelling that appears with the patient in the recumbent position and disappears in th...
journal_title:Neurosurgical review
pub_type: 杂志文章,评审
doi:10.1007/s10143-011-0325-6
更新日期:2012-01-01 00:00:00
abstract::Amyotrophic lateral sclerosis (ALS) is a progressive, degenerative disease of the nervous system. It affects adults in all age groups and leads to death few years after the diagnosis. The etiology is unknown, and there no convincing medical or surgical therapy Some diseases can mimic ALS. If diagnosed early these may ...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/BF01105785
更新日期:1998-01-01 00:00:00
abstract::Structural and functional neuroimaging studies are essential in the evaluation of individuals with partial epilepsy syndromes. Magnetic resonance imaging (MRI) is important to delineate structural abnormalities underlying seizure disorders, commonly including hippocampal sclerosis or cortical dysplasias. Identificatio...
journal_title:Neurosurgical review
pub_type: 杂志文章,评审
doi:10.1007/s10143-003-0293-6
更新日期:2003-10-01 00:00:00
abstract::Colloid cysts of the third ventricle are considered as benign lesions. The clinical manifestations are not clear in most of cases. Many treatment options are available and endoscopic removal of the cysts proves to be a very successful method especially if the lateral ventricles are moderately or severely dilated. Some...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-018-0956-y
更新日期:2019-03-01 00:00:00
abstract::Three patients suffering from hematogenous destructive spondylodiscitis were treated with one-session spondylectomy, bone graft-fusion and halo-device stabilization. A stable osseous fusion was achieved after three months with additional antibiotic therapy. ...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/BF00338196
更新日期:1991-01-01 00:00:00
abstract::It was suggested that D, L-Methadone might improve the clinical course of glioma patients. Owing to massive press coverage, patients demand the prescription of D, L-Methadone, but regarding its adjunctive use in glioma therapy there is no standard medication plan. Furthermore, it is not known which side effects the ad...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-020-01250-1
更新日期:2020-02-14 00:00:00
abstract::We aimed to evaluate whether bypass of the external carotid artery (ECA) to the middle cerebral artery (MCA) can be established by a short saphenous vein graft in order to increase the anastomosis patency. The method was performed to ten adult cadaver sides. We described a modified technique for bypass of the ECA to t...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-008-0138-4
更新日期:2008-07-01 00:00:00
abstract::From our observations of two patients, the problems of traumatic intracranial aneurysm are discussed. The prerequisites for recognition of such an aneurysm are the clinical findings, especially the angiographic control of the course of the aneurysm and, if possible, the results of histological examination. The difficu...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/BF01647129
更新日期:1980-01-01 00:00:00
abstract::This study aimed to find the factors that may affect the surgical outcomes of congenital tethered cord syndrome (TCS) in adults by evaluating the long-term surgical outcomes of 25 consecutive cases. Medical records of 79 TCS cases which underwent surgery in Bakırköy Research and Training Hospital for Neurology, Neuros...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-017-0842-z
更新日期:2018-01-01 00:00:00
abstract::The purpose of this study is to describe our series of nine unclippable and uncoilable ruptured aneurysms in eight patients treated by microsurgical wrapping with autologous muscle. Records were retrospectively reviewed for rebleeding rate, morbidity and mortality, changes in size or the aneurysm's configurations, and...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-012-0408-z
更新日期:2013-01-01 00:00:00
abstract::Intradiploic epidermoid tumor of the occipital bone was presented. There were neither intracranial extensions nor neurologic deficits. The lesion started as a painless mass under the scalp. The total removal of the tumor was associated with a good prognosis. ...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/BF00418080
更新日期:1996-01-01 00:00:00
abstract::Excision of a circumscribed spongioblastoma with intrapontine-intramesencephalic extension was performed via the floor of the fourth ventricle in two girls 14 and 5 years of age. The preoperative neurological deficits (severe hemiparesis, cerebellar, and sixth and seventh cranial nerve disturbances) showed slow but co...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/BF01743035
更新日期:1983-01-01 00:00:00
abstract::Although abundant in nature, fungi are infrequently pathogenic in humans. CNS fungal infections in non-immunocompromised individuals are uncommon. We discuss here the case of an otherwise healthy black woman with an isolated mass of the cerebellopontine angle identified as Blastomyces dermatitidis, successfully treate...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s101430050053
更新日期:1999-10-01 00:00:00
abstract::A new technique for interbody lumbar spondylodesis using a new cancellous metal, plug-shaped construct was performed in 35 cases with spondylolisthesis or lumbar instability. All of these patients have had severe low-back pain for years, some with radicular symptoms and had been treated unsuccessfully for years. In a ...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/BF00638889
更新日期:1990-01-01 00:00:00
abstract::The spinal nerve can be pinched between the transverse process of the fifth lumbar vertebra and the sacral ala. The patients are divided into two types: elderly persons with degenerative scoliosis and somewhat younger adults with isthmic spondylolisthesis. For the first time, we describe extraforaminal impingement of ...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-010-0300-7
更新日期:2010-04-01 00:00:00
abstract::Although several studies have suggested that aneurysmal wall inflammation and laminar thrombus are associated with the rupture of saccular aneurysms, the mechanisms leading to the rupture remain obscure. We performed full exposure of aneurysms before clip application and attempted to keep the fibrin cap on the rupture...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-015-0628-0
更新日期:2015-07-01 00:00:00
abstract::Brachytherapy (BT) for glioblastoma multiforme (GBM) involves the use of radioactive isotopes to deliver ionizing radiation directly into the tumor bed. Its application as a means to prolong survival in GBM patients over the past few decades has come with variable success. The objective of this review is to describe t...
journal_title:Neurosurgical review
pub_type: 杂志文章,评审
doi:10.1007/s10143-016-0727-6
更新日期:2017-04-01 00:00:00
abstract::We report the case of a patient with two distinct brain tumors. A meningioma was resected surgically. Nine months later a glioblastoma appeared in the same region, but at a different site. This was not treated, because the patient died. The clinical significance and etiology of these tumors are considered. ...
journal_title:Neurosurgical review
pub_type: 杂志文章,评审
doi:10.1007/BF00306823
更新日期:1994-01-01 00:00:00
abstract::With the increasing number of endovascular interventions during the last years, the number of procedure-related complications has risen accordingly. Despite sophisticated and effective endovascular treatments for acute thromboembolic events during intervention, vessel occlusion can remain refractory to medical and end...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-010-0283-4
更新日期:2011-01-01 00:00:00
abstract::Postoperative epidural haematoma distant to a site of craniotomy is a rare but possibly hazardous complication. We report a 31-year-old female who presented with a history of chronic hydrocephalus due to fourth-ventricular plexus papilloma. Following resection of the posterior fossa tumour with intraoperative placemen...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-003-0315-4
更新日期:2004-04-01 00:00:00
abstract::Eosinophilic granuloma is an uncommon lesion, often self-limiting. A location in the spine is rare; until now, only 35 cases have been reported. MRI is the most effective diagnostic technique, although conventional X-ray can also be useful as a first approach. Therapy consists of immobilization of the patients, surger...
journal_title:Neurosurgical review
pub_type: 杂志文章,评审
doi:10.1007/BF00383729
更新日期:1995-01-01 00:00:00
abstract::MR imaging of the brain has made tremendous progress during the last years. This technique is generally superior to computed tomography (CT) in brain tumors, due to its capability for direct imagining in various planes and its high tissue contrast. Moreover, the detectability and differentiation of extraaxial tumors, ...
journal_title:Neurosurgical review
pub_type: 杂志文章,评审
doi:10.1007/BF01741480
更新日期:1989-01-01 00:00:00
abstract::A hypothalamic hamartoma associated with true precocious puberty in a 7-month-old girl is hereby reported. Hormonal studies disclosed elevated serum levels of luteinizing hormone (LH) and follicle stimulating hormone, both of which responded well to LH-releasing hormone stimulation. Following a subtotal removal of the...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/BF00258250
更新日期:1993-01-01 00:00:00
abstract::Supplemental education is desirable for neurosurgical training, and the use of human cadaver specimen and virtual reality models is routine. An in vivo porcine training model for cranial neurosurgery was introduced in 2005, and our recent experience with this unique model is outlined here. For the first time, porcine ...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-014-0572-4
更新日期:2015-01-01 00:00:00
abstract::Polyostotic fibrous dysplasia affects many bones of the skeleton and usually on one side only. In monostotic variety only one bone is affected. The condition which usually starts in early childhood is at first active, gradually becomes quiescent and finally with termination of skeletal growth becomes inactive and ceas...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/BF01837749
更新日期:1981-01-01 00:00:00
abstract::The authors describe a case of hemifacial spasm associated with Marfan's syndrome. A 24-year-old-woman suffered from left hemifacial spasm for 6 years. She had undergone surgical treatments for bilateral ectopia lentis and kyphoscoliosis in the second decade of life. She also had unusually long and slim limbs with ara...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/BF02389321
更新日期:1998-01-01 00:00:00