Abstract:
:A computer program, BRUCE, was developed for the identification of transfer-messenger RNA (tmRNA) genes. The program employs heuristic algorithms to search for a tRNA(Ala)-like secondary structure surrounding a short sequence encoding the tag peptide. In the 57 completely sequenced bacterial genomes where tmRNA genes have been reported previously, BRUCE identified all with no false positives. In addition, BRUCE found 99 of the 100 tmRNAs identified previously in other bacteria, red chloroplasts and cyanelles. The output of the program reports the proposed tRNA secondary structure, the tmRNA gene sequence and the tag peptide.
journal_name
Nucleic Acids Resjournal_title
Nucleic acids researchauthors
Laslett D,Canback B,Andersson Sdoi
10.1093/nar/gkf459keywords:
subject
Has Abstractpub_date
2002-08-01 00:00:00pages
3449-53issue
15eissn
0305-1048issn
1362-4962journal_volume
30pub_type
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