Abstract:
:To achieve local control of malignant glioma, we designed a postoperative stereotactic radiotherapy using a micro-multileaf collimator (micro-MLC). The purpose of this study was to clarify the feasibility of this treatment. The treatment was performed in six patients who met the following eligibility criteria: (1) supratentorial tumor, (2) residual tumor volume < or = 40 cm3, and (3) Karnofsky performance status > or = 70. The three planning target volumes (PTVs), which consisted of restricted PTV (RPTV), intermediate PTV (IPTV), and extended PTV (EPTV), defined as the residual tumor plus a 1 cm, 2 cm, and 3 cm margins, respectively, and total dose delivery of 60-68 Gy, 52-60 Gy, and 44-52 Gy to the isocenters of RPTV, IPTV, and EPTV, respectively, in 4 Gy per fraction at five fractions per week, were established. The beam arrangement and the conformal blockade with a micro-MLC for the optimal treatment plan were designed. The treatment plans showed the high dose conformation to EPTV, the appropriate dose gradients in the three PTVs with the high dose homogeneity to RPTV, and the tolerated dose to critical structures. Following the plans, treatment was performed. The clinical findings more than 12 months after the treatment supported its possible use. We conclude that this treatment is feasible at least in selected patients.
journal_name
Neurosurg Revjournal_title
Neurosurgical reviewauthors
Isaka T,Nishiyama K,Nakagawa H,Suzuki T,Wada Kdoi
10.1007/s101430100185keywords:
subject
Has Abstractpub_date
2002-06-01 00:00:00pages
166-73issue
3eissn
0344-5607issn
1437-2320journal_volume
25pub_type
临床试验,杂志文章abstract::The early identification and optimized treatment of wound dehiscence are a complex issue, with implications on the patient's clinical and psychological postoperative recovery and on healthcare system costs. The most widely accepted treatment is surgical debridement (also called "wash out"), performed in theater under ...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-018-1022-5
更新日期:2020-02-01 00:00:00
abstract::Patients with craniocervical disorders (CCD) show a wide variety of symptoms and signs suggesting cerebellar and/or high cervical lesion. The anatomic localization of respiratory centers and their possible injury may explain the presence of respiratory disturbances in these diseases. The aim of this preliminary study ...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/pl00011947
更新日期:2000-09-01 00:00:00
abstract::With the increasing number of endovascular interventions during the last years, the number of procedure-related complications has risen accordingly. Despite sophisticated and effective endovascular treatments for acute thromboembolic events during intervention, vessel occlusion can remain refractory to medical and end...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-010-0283-4
更新日期:2011-01-01 00:00:00
abstract::Multilevel discectomy and inter-vertebral body fusion combined with anterior plate-screw fixation is the common procedure in cervical spine surgery. The correct placement of the screws is an important factor for the outcome of these operations. Yet no systematic approach has been undertaken to optimize the geometry of...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-005-0386-5
更新日期:2005-10-01 00:00:00
abstract::Between 1987 and 1991 we performed a unilateral or bilateral frontoorbital advancement to correct trigono- or plagiocephaly in 10 children: Three-dimensional CT provides an exact basis for operation planning. Titanium miniplates allow an already primarily rather stable osteosynthesis. The best time for this interventi...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/BF00345936
更新日期:1992-01-01 00:00:00
abstract::Patients with aneurysmal subarachnoid hemorrhage (SAH) are frequently complicated by acute cardiac dysfunctions, including cardiac wall motion abnormality (WMA). Massive release of catecholamine into the systemic circulation after aneurysmal rupture is believed to result in WMA, and poor-grade SAH seems to be the most...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-012-0424-z
更新日期:2013-04-01 00:00:00
abstract::Twenty-six patients with oculomotor nerve palsy due to cerebral aneurysms were examined. There were six males and twenty females with a mean age of 55 years. 25 of the 26 aneurysms were located at the junction of the internal carotid and the posterior communicating artery and one was at the junction of the basilar art...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/BF01741485
更新日期:1989-01-01 00:00:00
abstract::Sinus pericranii is a rare vascular abnormality characterised by abnormal connections between the intra- and extracranial venous systems and is usually found in children. In most instances, a sinus pericranii presents as a soft scalp swelling that appears with the patient in the recumbent position and disappears in th...
journal_title:Neurosurgical review
pub_type: 杂志文章,评审
doi:10.1007/s10143-011-0325-6
更新日期:2012-01-01 00:00:00
abstract::Although several studies have suggested that aneurysmal wall inflammation and laminar thrombus are associated with the rupture of saccular aneurysms, the mechanisms leading to the rupture remain obscure. We performed full exposure of aneurysms before clip application and attempted to keep the fibrin cap on the rupture...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-015-0628-0
更新日期:2015-07-01 00:00:00
abstract::The purpose of this paper is to provide a comprehensive review encompassing the syndromes associated with the lower cranial nerves (LCNs). We will discuss the anatomy of some of these syndromes and the historical contributors after whom they were named. The LCNs can be affected individually or in combination, since th...
journal_title:Neurosurgical review
pub_type: 杂志文章,评审
doi:10.1007/s10143-020-01344-w
更新日期:2020-07-08 00:00:00
abstract::The purpose of this study was to investigate and to compare the effects of microsuturing to that of tissue adhesives (Tisseel) on the healing of anastomosing peripheral nerve incisions. Forty-five Wistar-Albino rats were placed in special cages and separated into three groups (n = 15). In the control group, biliteral ...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/BF01105896
更新日期:1997-01-01 00:00:00
abstract::A primary xanthomatous tumor is very rare in the central nervous system (CNS). Here we report the case of a fibroxanthoma arising from the dura mater of the cerebrum that demonstrated no systemic disease or metabolic abnormalities. A 19-month-old, otherwise healthy boy was found to have an enlarged head. Magnetic reso...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s101430050019
更新日期:1999-12-01 00:00:00
abstract::Paraffin-embedded surgical specimens from 55 meningiomas were immunostained after microwave processing using the streptavidin/peroxidase method and the monoclonal antibody (moAb) MIB-1 to the Ki-67 antigen. The authors assessed proliferative labelling index (LI) from a series of surgically removed meningiomas using im...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-003-0261-1
更新日期:2003-07-01 00:00:00
abstract::A multidimensional concept of diagnosis and treatment of mental disorders is presented. Major contributions to basic research come from pharmacological experiments. Clinical outcome in treatment of endogenous depression can be assessed by rating scales and psychophysiological tests and correlated with the serum level ...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/BF01650030
更新日期:1980-01-01 00:00:00
abstract::The aim of this study was to determine the efficacy and safety of intrathecal baclofen therapy delivered by a programmable pump for the chronic treatment of spinal spasticity. Twelve patients with intractable spasticity caused by spinal cord injuries underwent implantation of a programmable continuous infusion pump af...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-002-0221-1
更新日期:2002-08-01 00:00:00
abstract::There are many satisfactory long-term outcomes after posterolateral fusion (PLF) for degenerative lumbar spondylolisthesis (DLS); nonunion cases have also achieved good clinical outcomes. Facet fusion (FF), a minimally invasive evolution of PLF, also resulted in good clinical outcomes. We aimed to assess the course of...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-021-01479-4
更新日期:2021-01-20 00:00:00
abstract::Chemotherapy of malignant glioma has been discussed in relation to recent advances in experimental and clinical studies. It is now obvious that chemotherapy is of increasing importance in the multidisciplinary treatment of malignant gliomas. Survival time of patients was prolonged by intensive and prolonged chemothera...
journal_title:Neurosurgical review
pub_type: 临床试验,杂志文章,评审
doi:10.1007/BF01743285
更新日期:1984-01-01 00:00:00
abstract::Von Hippel-Lindau disease (VHL) is a hereditary cancer syndrome caused by germline mutations of the VHL tumor suppressor gene. Major progress has been made in the last decade in both clinical and fundamental aspects of VHL. The VHL gene product, pVHL, has major and multiple functions: pVHL regulates not only first ang...
journal_title:Neurosurgical review
pub_type: 杂志文章,评审
doi:10.1007/s101430050024
更新日期:2000-03-01 00:00:00
abstract::A new technique for interbody lumbar spondylodesis using a new cancellous metal, plug-shaped construct was performed in 35 cases with spondylolisthesis or lumbar instability. All of these patients have had severe low-back pain for years, some with radicular symptoms and had been treated unsuccessfully for years. In a ...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/BF00638889
更新日期:1990-01-01 00:00:00
abstract::Magnetic resonance angiography (MRA) is increasingly used as a noninvasive means to assess internal carotid artery (ICA) stenosis. When used alone, however, MRA may not be sufficiently accurate in certain settings to determine whether ICA disease meets surgical criteria. Although MRA has been recognized to overestimat...
journal_title:Neurosurgical review
pub_type: 杂志文章,评审
doi:10.1007/s10143-004-0354-5
更新日期:2005-04-01 00:00:00
abstract::Hemangioblastoma is a rare benign tumor that consists of neoplastic vacuolated stromal cells and highly developed capillary blood vessels. These tumors are almost exclusively found in the central nervous system, but in extremely rare cases, it can arise in peripheral nerves. In the majority of cases, it occurs sporadi...
journal_title:Neurosurgical review
pub_type: 杂志文章,评审
doi:10.1007/s10143-014-0587-x
更新日期:2015-01-01 00:00:00
abstract::Case report of traumatic induced tetraplegia due to multiple cranio-cervical abnormalities with cord compression at the level of C4/C5. Diagnostic and operative procedure. ...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/BF01743105
更新日期:1983-01-01 00:00:00
abstract::This short paper summarizes the basic concept and the technology of a new computed radiographic system which uses an energy-storage phosphorus panel called "Imaging Plate" as an image sensor. The "Imaging Plate" can be used to obtain radiographs in exactly the same way as the screen-film combination is used in convent...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/BF01744878
更新日期:1985-01-01 00:00:00
abstract::Postoperative epidural haematoma distant to a site of craniotomy is a rare but possibly hazardous complication. We report a 31-year-old female who presented with a history of chronic hydrocephalus due to fourth-ventricular plexus papilloma. Following resection of the posterior fossa tumour with intraoperative placemen...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-003-0315-4
更新日期:2004-04-01 00:00:00
abstract::Although endovascular or surgical treatment has been performed for preventing the rupture of saccular cerebral aneurysms (sCA), in some patients, the aneurysms may recur and require retreatment. We aimed to investigate the clinical and radiological outcomes of treating recurrent sCA. We retrospectively evaluated the d...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-020-01259-6
更新日期:2020-02-21 00:00:00
abstract::As a result of their presumed benign natural history, cerebral capillary telangiectasias (CCTs) are infrequently addressed in the neurosurgical literature. We performed a comprehensive review of CCTs via the PubMed database to synthesize overall epidemiological, radiographic, natural history, and treatment results. Ac...
journal_title:Neurosurgical review
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s10143-012-0435-9
更新日期:2013-04-01 00:00:00
abstract::A neuroendoscopic biopsy is a minimally invasive and useful procedure for the diagnosis and initial management of tumor-associated hydrocephalus. We describe the nationwide investigation of the current status of neuroendoscopic biopsy for intra- and paraventricular tumors in children, as well as the treatment of tumor...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-015-0629-z
更新日期:2015-10-01 00:00:00
abstract::During surgeries in the upper cerebellopontine angle (CPA), the superior petrosal veins (SPVs) often act as obstacles; and their sectioning sometimes causes serious complications. In this study, we introduced a classification system for the SPVs wherein their tributaries were classified into four groups on the basis o...
journal_title:Neurosurgical review
pub_type: 杂志文章,评审
doi:10.1007/s10143-014-0548-4
更新日期:2014-10-01 00:00:00
abstract::The introduction of computed tomography (CT) and magnetic resonance (MR) imaging has resulted in the detection of increasing numbers of asymptomatic intraventricular tumors. Establishing the correct preoperative diagnosis is important to prevent unnecessary surgical intervention. Our study includes nine cases of benig...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-004-0353-6
更新日期:2005-04-01 00:00:00
abstract::Surgery is the only therapeutic option for cerebral cavernous malformations (CCM) and is proposed, whenever possible, after haemorrhagic events, neurological symptoms, or epilepsy, radiosurgery being a controversial alternative in some cases. However, there is no treatment for non-accessible lesions, such as brainstem...
journal_title:Neurosurgical review
pub_type: 杂志文章,评审
doi:10.1007/s10143-018-01074-0
更新日期:2019-06-01 00:00:00