Abstract:
:Women with polycystic ovary syndrome (PCOS) have several cardiovascular disease risk factors. Since hyperhomocysteinemia is associated with early atherosclerosis, it was postulated that the homocysteine levels are higher in PCOS patients than in control subjects which, therefore, may explain the cardiovascular disease risk. Thirty-five women with PCOS and 20 healthy subjects were studied. Endocrine assays, lipid profile, homocysteine and insulin level determinations, and ultrasound evaluation were performed in all subjects. We found significantly higher mean plasma homocysteine concentrations in patients with PCOS as compared with controls (10.4 +/- 4.4 vs. 7.2 +/- 1.5 ng/dl; p < 0.003). These data show that in PCOS early atherosclerosis is not exclusively dependent on hyperinsulinemia and elevated lipid profile - PCOS patients are exposed to significantly higher homocysteine levels which might increase the cardiovascular disease risk.
journal_name
Gynecol Obstet Investjournal_title
Gynecologic and obstetric investigationauthors
Loverro G,Lorusso F,Mei L,Depalo R,Cormio G,Selvaggi Ldoi
10.1159/000058367keywords:
subject
Has Abstractpub_date
2002-01-01 00:00:00pages
157-62issue
3eissn
0378-7346issn
1423-002Xpii
58367journal_volume
53pub_type
杂志文章abstract::We experienced a typical case of eclampsia. After the onset of eclampsia, we performed magnetic resonance imaging angiography (MRI angiography) to estimate the function of the cerebral artery. MRI angiography showed that spasm occurred in many cerebral arteries. The spasm was still observed in some arteries 13 day aft...
journal_title:Gynecologic and obstetric investigation
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journal_title:Gynecologic and obstetric investigation
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journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
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journal_title:Gynecologic and obstetric investigation
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doi:10.1159/000010167
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journal_title:Gynecologic and obstetric investigation
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journal_title:Gynecologic and obstetric investigation
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journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000293673
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journal_title:Gynecologic and obstetric investigation
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journal_title:Gynecologic and obstetric investigation
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journal_title:Gynecologic and obstetric investigation
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journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000443829
更新日期:2016-01-01 00:00:00
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journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
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journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000293771
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pub_type: 杂志文章
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更新日期:2010-01-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000298964
更新日期:1985-01-01 00:00:00
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journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000293633
更新日期:1989-01-01 00:00:00
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journal_title:Gynecologic and obstetric investigation
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:Gynecologic and obstetric investigation
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journal_title:Gynecologic and obstetric investigation
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journal_title:Gynecologic and obstetric investigation
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journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000293009
更新日期:1991-01-01 00:00:00
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journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000294853
更新日期:1992-01-01 00:00:00
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journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000293032
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journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292732
更新日期:1992-01-01 00:00:00
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journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292521
更新日期:1994-01-01 00:00:00
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journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000291505
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