International variation in ethics committee requirements: comparisons across five Westernised nations.

abstract：BACKGROUND:In most socialised health systems there are formal processes that manage resource scarcity and determine the allocation of funds to health services in accordance with their priority. In this analysis, part of a larger qualitative study examining the ethical issues entailed in doctors' participation as techni...

journal_title：BMC medical ethics

authors： Gallagher S,Little M,Hooker C

更新日期：2018-07-24 00:00:00

abstract：BACKGROUND:HIV prevention research in resource-limited countries is associated with a variety of ethical dilemmas. Key amongst these is the question of what constitutes an appropriate standard of health care (SoC) for participants in HIV prevention trials. This paper describes a community-focused approach to develop a ...

journal_title：BMC medical ethics

authors： Vallely A,Shagi C,Lees S,Shapiro K,Masanja J,Nikolau L,Kazimoto J,Soteli S,Moffat C,Changalucha J,McCormack S,Hayes RJ

更新日期：2009-10-09 00:00:00

abstract：BACKGROUND:The past 10 years have witnessed a significant growth in sharing of health data for secondary uses. Alongside this there has been growing interest in the public acceptability of data sharing and data linkage practices. Public acceptance is recognised as crucial for ensuring the legitimacy of current practice...

journal_title：BMC medical ethics

authors： Aitken M,de St Jorre J,Pagliari C,Jepson R,Cunningham-Burley S

更新日期：2016-11-10 00:00:00

abstract：BACKGROUND:Surgery for intersex infants should be delayed until individuals are able to decide for themselves, except where it is a medical necessity. In an ideal world, this single principle would suffice and such surgeries could be totally prohibited. Unfortunately, the world is not perfect, and, in some places, inte...

journal_title：BMC medical ethics

authors： Behrens KG

更新日期：2020-10-29 00:00:00

abstract：BACKGROUND:Care-dependency constitutes an important issue with regard to the approval of end-of-life decisions, yet attitudes towards assisted suicide and euthanasia are understudied among care-dependent older adults. We assessed attitudes towards assisted suicide and euthanasia and tested empirical correlates, includi...

journal_title：BMC medical ethics

authors： Stolz E,Mayerl H,Gasser-Steiner P,Freidl W

更新日期：2017-12-07 00:00:00

abstract：BACKGROUND:The boundaries between health-related research and practice have become blurred as initiatives traditionally considered to be practice (e.g., quality improvement, program evaluation) increasingly use the same methodology as research. Further, the application of different ethical requirements based on this di...

journal_title：BMC medical ethics

authors： Ondrusek NK,Willison DJ,Haroun V,Bell JA,Bornbaum CC

更新日期：2015-07-07 00:00:00

abstract：BACKGROUND:Public satisfaction with policy process influences the legitimacy and acceptance of policies, and conditions the future political process, especially when contending ethical value judgments are involved. On the other hand, public involvement is required if effective policy is to be developed and accepted. M...

journal_title：BMC medical ethics

authors： Sato H,Akabayashi A,Kai I

更新日期：2005-01-20 00:00:00

abstract：BACKGROUND:Few studies have examined factors associated with willingness of people living with HIV (PLHIV) to participate in HIV treatment clinical trials in Sub-Saharan Africa. We assessed the factors associated with participation of PLHIV in HIV treatment clinical trials research at a large urban clinical and researc...

journal_title：BMC medical ethics

authors： Sebatta DE,Siu G,Nabeta HW,Anguzu G,Walimbwa S,Lamorde M,Bukenya B,Kambugu A

更新日期：2020-08-24 00:00:00

abstract：BACKGROUND:There is a permanent need to evaluate and develop the ethical quality of scientific research and to widen knowledge about the effects of ethical issues. Therefore we evaluated whether informed consent is related to implementation and success in a lifestyle intervention study with older research participants....

journal_title：BMC medical ethics

authors： Länsimies-Antikainen H,Pietilä AM,Laitinen T,Kiviniemi V,Rauramaa R

更新日期：2010-06-08 00:00:00

abstract：BACKGROUND:Moral Case Deliberations (MCDs) are reflective dialogues with a group of participants on their own moral dilemmas. Although MCD is successful as clinical ethics support (CES), it also has limitations. 1. Lessons learned from individual MCDs are not shared in order to be used in other contexts 2. Moral learni...

journal_title：BMC medical ethics

authors： Hartman LA,Metselaar S,Molewijk AC,Edelbroek HM,Widdershoven GAM

更新日期：2018-12-22 00:00:00

abstract：BACKGROUND:The study examined the knowledge and attitudes to personal genomics testing for complex diseases among Nigerians and identified how the knowledge and attitudes vary with gender, age, religion, education and related factors. METHODS:Data were collected using qualitative method in 2 districts of the Federal C...

journal_title：BMC medical ethics

authors： Fagbemiro L,Adebamowo C

更新日期：2014-04-27 00:00:00

abstract：BACKGROUND:Cancer patients are at risk of developing blood clots in their veins - venous thromboembolism (VTE) - which often takes the form of a pulmonary embolism or deep vein thrombosis. The risk increases with advanced disease. Evidence based treatment is low molecular weight heparin (LMWH) by daily subcutaneous inj...

journal_title：BMC medical ethics

authors： Sheard L,Prout H,Dowding D,Noble S,Watt I,Maraveyas A,Johnson M

更新日期：2012-09-04 00:00:00

abstract：BACKGROUND:Regardless of national contexts, the institutions responsible for research ethics, founded on international regulations, are all expected to be structured and to operate in a common way. Our experience with several countries on different continents, however, has raised questions in this regard. This article ...

journal_title：BMC medical ethics

authors： Sambiéni NE

更新日期：2018-06-15 00:00:00

abstract：BACKGROUND:Consenting for retrospective medical records-based research (MR) and leftover tissue-based research (TR) continues to be controversial. Our objective was to survey Saudis attending outpatient clinics at a tertiary care hospital on their personal preference and perceptions of norm and current practice in rela...

journal_title：BMC medical ethics

authors： Al-Qadire MM,Hammami MM,Abdulhameed HM,Al Gaai EA

更新日期：2010-10-18 00:00:00

abstract：BACKGROUND:Differences in perception and potential disagreements between parents and professionals regarding the attitude for resuscitation at the limit of viability are common. This study evaluated in healthcare professionals whether the decision to resuscitate at the limit of viability (intensive care versus comfort ...

journal_title：BMC medical ethics

authors： Papadimitriou V,Tosello B,Pfister R

更新日期：2019-10-22 00:00:00

abstract：BACKGROUND:The work of Research Ethics Boards (REBs), especially when involving genetics research and biobanks, has become more challenging with the growth of biotechnology and biomedical research. Some REBs have even rejected research projects where the use of a biobank with coded samples was an integral part of the s...

journal_title：BMC medical ethics

authors： Auray-Blais C,Patenaude J

更新日期：2006-04-06 00:00:00

abstract：BACKGROUND:Precision medicine (PM) is an emerging approach to individualized care. It aims to help physicians better comprehend and predict the needs of their patients while effectively adopting in a timely manner the most suitable treatment by promoting the sharing of health data and the implementation of learning hea...

journal_title：BMC medical ethics

authors： Geneviève LD,Martani A,Shaw D,Elger BS,Wangmo T

更新日期：2020-02-19 00:00:00

abstract：BACKGROUND:In 2009, Dr. Paolo Zamboni proposed chronic cerebrospinal venous insufficiency (CCSVI) as a possible cause of multiple sclerosis (MS). Although his theory and the associated treatment ("liberation therapy") received little more than passing interest in the international scientific and medical communities, hi...

journal_title：BMC medical ethics

authors： Pullman D,Zarzeczny A,Picard A

更新日期：2013-02-12 00:00:00

abstract：BACKGROUND:A child is a developing person with evolving capacities that include autonomy, mental (decisional) capacity and capacity to assume responsibility. Hence, children are entitled to participatory (autonomy) rights in South Africa as observed in the Children's Act 38 of 2005. According to section 129 of the Act ...

journal_title：BMC medical ethics

authors： Ganya W,Kling S,Moodley K

更新日期：2016-11-02 00:00:00

abstract：BACKGROUND:Community consultation is increasingly recommended, and in some cases, required by ethical review boards for research that involves higher levels of ethical risk such as international research and research with vulnerable populations. In designing a randomised control trial of a mental health intervention us...

journal_title：BMC medical ethics

authors： Shanks L,Moroni C,Rivera IC,Price D,Clementine SB,Pintaldi G

更新日期：2015-06-02 00:00:00

abstract：BACKGROUND:Researchers are required to seek consent from Indigenous communities prior to conducting research but there is inadequate information about how Indigenous people understand and become fully engaged with this consent process. Few studies evaluate the preference or understanding of the consent process for rese...

journal_title：BMC medical ethics

authors： Fitzpatrick EFM,Macdonald G,Martiniuk ALC,D'Antoine H,Oscar J,Carter M,Lawford T,Elliott EJ

更新日期：2017-05-11 00:00:00

abstract：BACKGROUND:How should clinical ethics support services such as clinical ethics committees (CECs) be implemented and evaluated? We argue that both the CEC itself and the implementation of the CEC should be considered as 'complex interventions'. MAIN TEXT:We present a research project involving the implementation of CEC...

journal_title：BMC medical ethics

authors： Magelssen M,Karlsen H,Pedersen R,Thoresen L

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:The increased use of human biological material for cell-based research and clinical interventions poses risks to the privacy of patients and donors, including the possibility of re-identification of individuals from anonymized cell lines and associated genetic data. These risks will increase as technologies ...

journal_title：BMC medical ethics

authors： Ogbogu U,Burningham S,Ollenberger A,Calder K,Du L,El Emam K,Hyde-Lay R,Isasi R,Joly Y,Kerr I,Malin B,McDonald M,Penney S,Piat G,Roy DC,Sugarman J,Vercauteren S,Verhenneman G,West L,Caulfield T

更新日期：2014-02-03 00:00:00

abstract：BACKGROUND:Although informed consent is an integral part of clinical practice, its current doctrine remains mostly a matter of law and mainstream ethics rather than empirical research. There are scarce empirical data on patients' perceived purpose of informed consent, which may include administrative routine/courtesy g...

journal_title：BMC medical ethics

authors： Hammami MM,Al-Gaai EA,Al-Jawarneh Y,Amer H,Hammami MB,Eissa A,Qadire MA

更新日期：2014-01-10 00:00:00

abstract：BACKGROUND:Since 2010, the European Journal of Anaesthesiology has required the reporting of five items concerning ethical approval in articles describing human research: ethics committee's name and address, chairperson's name, study's protocol number and approval date. We aimed to assess whether this requirement has h...

journal_title：BMC medical ethics

authors： Zoccatelli D,Tramèr MR,Elia N

更新日期：2018-06-08 00:00:00

abstract：BACKGROUND:Expanded access is the use of investigational drugs (IDs) outside of clinical trials. Generally it is performed in patients with serious and life-threatening diseases who cannot be treated satisfactorily with authorized drugs. Legal regulations of expanded access to IDs have been introduced among others in t...

journal_title：BMC medical ethics

authors： Borysowski J,Górski A

更新日期：2020-11-18 00:00:00

abstract：:Pediatric biobanking is considered important for generating biomedical knowledge and improving (pediatric) health care. However, the inclusion of children's samples in biobanks involves specific ethical issues. One of the main concerns is how to appropriately engage children in the consent procedure. We suggest that c...

journal_title：BMC medical ethics

authors： Giesbertz NA,Melham K,Kaye J,van Delden JJ,Bredenoord AL

更新日期：2016-10-12 00:00:00

abstract：BACKGROUND:The use of tissue collected at a forensic post-mortem for forensic genetics research purposes remains of ethical concern as the process involves obtaining informed consent from grieving family members. Two forensic genetics research studies using tissue collected from a forensic post-mortem were recently ini...

journal_title：BMC medical ethics

authors： Heathfield LJ,Maistry S,Martin LJ,Ramesar R,de Vries J

更新日期：2017-11-29 00:00:00

abstract：BACKGROUND:The individual informed consent model remains critical to the ethical conduct and regulation of research involving human beings. Parental informed consent process in a rural setting of northern Ghana was studied to describe comprehension and retention among parents as part of the evaluation of the existing i...

journal_title：BMC medical ethics

authors： Oduro AR,Aborigo RA,Amugsi D,Anto F,Anyorigiya T,Atuguba F,Hodgson A,Koram KA

更新日期：2008-06-19 00:00:00

abstract：:The 3rd Pan-African Ethics Human Rights and Medical Law (3rd EHRML) conference was held in Johannesburg on July 7, 2013, as part of the Africa Health Congress. The conference brought together bioethicists, researchers and scholars from South Africa, Zimbabwe, Kenya and Nigeria working in the field of bioethics as well...

journal_title：BMC medical ethics

authors： Chima SC,Mduluza T,Kipkemboi J

更新日期：2013-01-01 00:00:00