Abstract:
OBJECTIVE:To study the effects of diuretic stimulation with frusemide and mannitol on the renal resistive index (RI) of the undilated unobstructed porcine kidney. MATERIALS AND METHODS:Experiments were carried out on 14 pigs divided into two equal groups (A and B), under general anaesthesia. In all pigs both ureters were catheterized, thereby allowing urine output to be measured on each side separately, and an indwelling catheter in a femoral artery used to continuously measure the systemic blood pressure. Furthermore, in five pigs from each group, right renal blood flow was measured by ultrasonic flow probes placed around the renal arteries. The right kidney RI was measured at baseline and at 5-min intervals after frusemide (group A) and mannitol (group B) stimulation, for 75 min. RESULTS:Frusemide caused significant increases in diuresis (P < 0.001) and renal blood flow (P = 0.009). This was accompanied by a significant decrease in mean arterial pressure (P < 0.001). The RI was unaffected (P = 0.706), with mean values in group A of 0.58-0.65. Mannitol also caused a significant increase in diuresis (P < 0.001) and a subtle but significant decrease in mean arterial pressure (P < 0.001). However, renal blood flow was unaffected by the diuretic (P = 0.820); the mean RI values were unaffected, at 0.61-0.66 (P = 0.375). CONCLUSIONS:These results show that diuretic stimulation with frusemide or mannitol does not affect the RI of the unobstructed undilated porcine kidney, despite significant changes in diuresis, renal blood flow and mean arterial pressure.
journal_name
BJU Intjournal_title
BJU internationalauthors
Rawashdeh YF,Hørlyck A,Djurhuus JC,Frokiaer J,Mortensen Jdoi
10.1046/j.1464-4096.2001.01795.xkeywords:
subject
Has Abstractpub_date
2002-03-01 00:00:00pages
443-8issue
4eissn
1464-4096issn
1464-410Xpii
2634journal_volume
89pub_type
杂志文章abstract:OBJECTIVE:To evaluate contrast-enhanced ultrasonography (US) using cadence-contrast pulse sequencing (CPS) technology, compared with systematic biopsy for detecting prostate cancer, as grey-scale US has low sensitivity and specificity for detecting prostate cancer. PATIENTS AND METHODS:In all, 44 men with suspicious p...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2008.08038.x
更新日期:2009-02-01 00:00:00
abstract:OBJECTIVE:To assess the use of demucosalized ileum for bladder augmentation, following the same principles previously used with the sigmoid colon. PATIENTS AND METHODS:Eleven patients with bladder exstrophy or a neurogenic bladder had their bladders augmented with demucosalized ileum instead of the sigmoid colon, but ...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-4096.2001.lima.2465.x
更新日期:2001-11-01 00:00:00
abstract::The aims of this paper were to review the published literature on the role of HOX genes in the development of the normal prostate gland and in prostate cancer and to discuss the potential role of the HOX family member, Engrailed-2 (EN2), as a diagnostic test of PCa. Hox genes were first described in the fruit fly Dros...
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pub_type: 杂志文章,评审
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更新日期:2014-04-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2010.09986.x
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更新日期:2003-08-01 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:2016-10-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章,评审
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更新日期:2013-05-01 00:00:00
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pub_type: 杂志文章
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-4096.2001.2441.x
更新日期:2001-12-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章,评审
doi:10.1111/j.1464-410X.2009.08704.x
更新日期:2009-09-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2011-07-01 00:00:00
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pub_type: 临床试验,杂志文章,多中心研究
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更新日期:2005-02-01 00:00:00
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pub_type: 临床试验,杂志文章
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更新日期:2003-05-01 00:00:00
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更新日期:2012-12-01 00:00:00
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更新日期:2011-05-01 00:00:00
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更新日期:2012-01-01 00:00:00
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更新日期:2016-12-01 00:00:00
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pub_type: 杂志文章
doi:10.1111/j.1464-410X.2004.05115.x
更新日期:2004-11-01 00:00:00
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pub_type: 杂志文章
doi:10.1111/j.1464-410x.2003.04524.x
更新日期:2003-12-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章,随机对照试验
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更新日期:2006-06-01 00:00:00
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pub_type: 杂志文章
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更新日期:2012-03-01 00:00:00
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pub_type: 杂志文章
doi:10.1046/j.1464-410x.2001.02253.x
更新日期:2001-07-01 00:00:00
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pub_type: 杂志文章,评审
doi:10.1111/j.1464-410X.2009.09148.x
更新日期:2010-04-01 00:00:00
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pub_type: 杂志文章
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更新日期:2009-12-01 00:00:00
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pub_type: 杂志文章
doi:10.1111/j.1464-410X.2009.09096.x
更新日期:2010-07-01 00:00:00
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更新日期:2008-07-01 00:00:00