Abstract：
OBJECTIVE:To study the prevalence and presentation forms of hereditary hemorrhagic telangiectasia (HHT) among the population in our hospital area. MATERIALS AND METHODS:Descriptive, retrospective study of patients with the diagnosis of HHT from to 1999 at La Fe Hospital, Valencia. Family history, repeated epistaxis, mucocutaneous telangiectasis and visceral lesions, as well as administered treatments, and clinical course were evaluated. RESULTS:Seventeen patients were diagnosed during such time period, with ages ranging from 23 to 80 years. Eight patients had family histories. The most common symptoms included epistaxis and iron-deficiency anemia, followed by muco-cutaneous telangiectasis. Six patients had neurological, five pulmonary, five gastrointestinal, and three hepatic manifestations, usually secondary to vascular malformations at those levels. CONCLUSIONS:The prevalence of the disease maybe higher than previously reported. This disease should be considered in patients with repeated epistaxis and/or iron-deficiency anemia. The presence of telangiectasis that can suggest the diagnosis should be investigated. An early diagnosis of HHT can be useful for the early control of associated visceral malformations. Treatment of HHT should be tailored according to the clinical manifestations of the patient.
journal_name
Rev Clin Espjournal_title
Revista clinica espanolaauthors
Alonso Estellés R,Campo López C,Todolí Parra JA,Calabuig Alborch JRdoi
10.1016/s0014-2565(01)70935-6keywords:
subject
Has Abstractpub_date
2001-11-01 00:00:00pages
638-41issue
11eissn
0014-2565issn
1578-1860pii
13021069journal_volume
201pub_type
杂志文章abstract：:Amongst 1.202 genital samples studied, the microscopic exam revealed in 179 (14.8%) cases flora compatible with bacterial vaginitis. Of these 179 samples, Mobiluncus SP was observed in 35 (19.6%) using Gram staining and in 18 (10.1%) this microorganism was isolated in agar RLK and anaerobic atmosphere. Using biochemic...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1991-06-01 00:00:00
abstract：:In the present work we study the modifications in hydrosaline metabolism which occurred in two groups of healthy male individuals, one consisting of 15 young men (mean age of 20 years) and the other of 30 elderly subjects (mean age of 75 years) when the thirst test was performed for 48 hours. After performing the thir...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1991-07-01 00:00:00
abstract：:Results of clinical studies are contradictories, with different results in adults and children. Some studies detected a beneficial effect of Omega 3 (w3) fatty acid dietary intake in the risk of asthma and other studies have demonstrated a beneficial effect on clinical symptoms. In our area, a low intake of w3 fatty a...
journal_title：Revista clinica espanola
pub_type： 杂志文章,评审
doi：10.1157/13098496
更新日期：2007-01-01 00:00:00
abstract：:Laughter is associated to many physiological and psychological benefits. Although women laugh more than men do, the daily frequency of laughter does not seem to differ. Laughter in all its forms and manifestations is an indicator of family vitality and healthy couples. Laughter is very attractive at the interpersonal ...
journal_title：Revista clinica espanola
pub_type： 杂志文章,评审
doi：10.1016/j.rce.2010.10.013
更新日期：2011-07-01 00:00:00
abstract：:After recognizing smoking habit as a relevant problem in our media, the complex implications of this type of lifestyle are commented. After revising the main obstacles for achieving primary health care preventive measures not only for the patient, who frequently looks for a "treatment", but also for the professional w...
journal_title：Revista clinica espanola
pub_type： 杂志文章,评审
doi：
更新日期：1989-03-01 00:00:00
abstract：:A case of gastroenteritis due to Giardia lamblia with severe dehydration and complicated with arterial thrombosis, accompanied by eosinophilia and increased serum IgE levels, is presented. The relationship between Giardia and eosinophilia and allergic manifestations is discussed as well as its pathogenesis. ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1990-06-01 00:00:00
abstract：BACKGROUND:The RS3PE syndrome is a recently described uncommon disorder in the elderly patient; in the initial reports, it was characterized by an excellent prognosis with total remission. In contrast with rheumatoid arthritis and polymyalgia rheumatic, it has been related to HLA B7. Further works have questioned its b...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1999-12-01 00:00:00
abstract：OBJECTIVE:To summarise the evidence on interventions aimed at optimising the drug treatment of hospitalised elderly patients. MATERIAL AND METHODS:We conducted a search in the main medical literature databases, selecting prospective studies of hospitalised patients older than 65 years who underwent interventions aimed...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2016.01.005
更新日期：2016-05-01 00:00:00
abstract：:Two cases are reported of women aged 18 and 36 years respectively who developed a typical picture of hyperthyroidism by Graves Basedow disease (primary hyperthyroidism, diffuse goiter with increased uptake, positive stimulating thyroid antibodies, exophthalmos). These women had taken drugs for obesity which were prepa...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1996-08-01 00:00:00
abstract：:Type 2 diabetes mellitus is a major health problem with high prevalence, morbidity and mortality, and its medical treatment is growing in complexity due to patients' diverse clinical conditions. This article presents a consensus document by the Diabetes, Obesity and Nutrition Group of the Spanish Society of Internal M...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2020.06.005
更新日期：2020-07-13 00:00:00
abstract：:Cancer of unknown primary site (CUPS) is a heterogeneous entity defined by the presence of a histologically-proven metastatic neoplasm, in which the original tumor cannot be identified after a targeted study. The current guidelines for CUPS focus is not based on the search for the primary neoplasm but rather on the id...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/s0014-2565(09)71820-x
更新日期：2009-07-01 00:00:00
abstract：:Coeliac disease is the most frequent malabsortive syndrome in daily practice. However, its true prevalence is not exactly known. The symptoms vary from patient to patient, ranging from the classic presentation with diarrhea, weight loss and fatigue to oligosymptomatic forms, being the latter more common in adults. We ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：BACKGROUND:There are no simple and validated instruments for evaluating the training of specialists. OBJECTIVES:To analyze the reliability and validity of a computerized self-assessment method to quantify the acquisition of medical competences during the Internal Medicine residency program. METHODS:All residents of o...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2012.04.004
更新日期：2012-12-01 00:00:00
abstract：:A case is presented of Cushing's syndrome due to macronodular bilateral adrenal hyperplasia which is ACTH-independent as was demonstrated by the undetectable basal and after stimulation with metoprolol ACTH plasma levels. High cortisol levels is associated in this patient with empty sella turcica and anterior panhypop...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1992-03-01 00:00:00
abstract：OBJECTIVE:Miglitol belongs to the group of the inhibitors of the alpha-glucosidases and in several studies has demonstrated its usefulness in the improvement of the glycemic control in the different types of diabetic patients. The goal of our study was to analyze the usefulness of miglitol in the blood glucose and lipi...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1157/13056791
更新日期：2004-01-01 00:00:00
abstract：:The aim or our study was to evaluate the main clinical and etiological features or primary acute pericarditis with severe pericardial effusion without cardiac tamponade. Our experience included 35 patients with this problem diagnosed in the last 5 years. Patients with a previous potential etiology for acute pericardit...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/s0014-2565(06)72744-8
更新日期：2006-03-01 00:00:00
abstract：:Ogilvie's syndrome (OS) is a clinical condiction with the symptoms, signs and radiological appearances of acute bowell obstruction but without any apparent mechanical cause. Diagnosis and treatment are often delayed and many patients are still inappropriately managed which in turn results in an increase in morbidity a...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1995-11-01 00:00:00
abstract：OBJECTIVE:To study the prevalence of hepatitis delta and hepatitis C viruses (HDV and HCV) in patients infected with hepatitis B virus (HBV) with and without risk behaviors for the infection by these viruses and by the human immunodeficiency virus (HIV). MATERIALS AND METHODS:Clinical and serological study (January 19...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1994-10-01 00:00:00
abstract：:In an open-controlled trial--oral washes (20 patients) versus test (19 patients)--, we have studied the effects of AM3 (a new oral BRM) on clinical evolution of the recurrent stomatitis (RAS) syndrome. The results obtained at 6th month showed significant decreases on ulcer numbers (p less than 0.001) as well as in the...
journal_title：Revista clinica espanola
pub_type： 临床试验,杂志文章
doi：
更新日期：1991-05-01 00:00:00
abstract：:We report here the case of a patient with fluoxetine and selegiline induced serotonin syndrome, which presented as encephalopathy, generalized myoclonias, fever, stiffness and sweating, complicated with acute renal failure, rhabdomyolysis and disseminated intravascular coagulation findings. The patient died 6 days aft...
journal_title：Revista clinica espanola
pub_type： 杂志文章,评审
doi：
更新日期：2002-04-01 00:00:00
abstract：OBJECTIVE:Although the genetic component in colorectal carcinoma (CRC) is well established, some environmental factors, mainly dietary, can favor its development. The objective of this study is to evaluate the relationship between daily consumption of specific food groups and development of CRC. METHODS:We carried out...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1157/13063526
更新日期：2004-07-01 00:00:00
abstract：:The purpose of this study is to determine the characteristics of spirometric performance in a group of smokers and to carry out a prospective study of the changes in ventilatory lung function after smoking withdrawal. The ventilatory lung function was studied in 90 smokers and 30 non-smokers. Afterwards the smokers we...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1993-03-01 00:00:00
abstract：:In pneumonias, the short diagnostic results of non-invasive procedures lead frequently to use invasive techniques, among which we find pulmonary puncture aspiration (PPA). In this study, the profitability of PPA in the diagnosis of pneumonias is evaluated. One hundred and thirteen PPA were performed on 107 patients di...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1994-04-01 00:00:00
abstract：BACKGROUND:In the last few years, Strongyloides stercoralis has been repeatedly recovered from indigenous farmers in the Safor area (Valencia Community). The relationship between the different occupational activities, mainly farming, and the presence of strongyloidiasis was investigated. PATIENTS AND METHODS:A paired ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/s0014-2565(01)70755-2
更新日期：2001-02-01 00:00:00
abstract：BACKGROUND:Nosocomial infection (NI) is associated with an increase in resource consumption. The estimation of extra costs attributable to NI in a group of patients with catheter-related bacteremia (CRB) was the objective of the present study. METHODS:A matched case-control, study was conducted in a cohort population....
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1998-10-01 00:00:00
abstract：INTRODUCTION:Geographic tongue (GT) is a lesion of unknown origin associated with systemic diseases and therefore involves multidisciplinary care. METHODS:We performed a literature search of the PubMed, EMBASE, Web of Science and Cochrane databases. The selection criteria were consistent with the Preferred Reporting I...
journal_title：Revista clinica espanola
pub_type： 杂志文章,评审
doi：10.1016/j.rce.2018.05.006
更新日期：2018-12-01 00:00:00
abstract：INTRODUCTION:This study examined the association of self-care behavior and patients' knowledge about self-care with rehospitalization among older adults with heart failure (HF). METHODS:Case-control comparison (116 cases and 209 controls) nested in a prospective cohort of patients aged 65 years and older admitted for ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1157/13123185
更新日期：2008-06-01 00:00:00
abstract：:215 cases diagnosed of human leptospirosis in the Camagüey Province, Cuba, are studied, for the period between 1986 and 1990. The clinical and epidemiological features are studied, together with the anatomopathological study of the decreased. The most frequent complications and the treatment employed, including prophy...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1992-05-01 00:00:00
abstract：UNLABELLED:An inappropriate hospital use, defined as hospital utilization that could have been occurred at a lower attending level or in less time, increases costs, creates inefficient management and influences on attending quality. The objective of this work was to evaluate the appropriateness and inappropriateness of...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：2000-12-01 00:00:00
abstract：OBJECTIVES:To assess the cost-effectiveness of a nucleic acid amplification test (FluoroType MTB®) in pleural fluid (PF) and sputum to diagnose tuberculous pleural effusion (TPE). We also analysed the increase in diagnostic yield of a second FluoroType MTB® test, obtained through a new thoracentesis, when the first had...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2020.04.010
更新日期：2020-06-01 00:00:00
