[AM3 (a biological response modifier) in the treatment of recurrent aphthous stomatitis. Clinical evaluation and preliminary studies on NK (CD16) cells and their pathogenic role in the syndrome].

Abstract:

:In an open-controlled trial--oral washes (20 patients) versus test (19 patients)--, we have studied the effects of AM3 (a new oral BRM) on clinical evolution of the recurrent stomatitis (RAS) syndrome. The results obtained at 6th month showed significant decreases on ulcer numbers (p less than 0.001) as well as in their mean duration time (p less than 0.001) due to the AM3 treatment. From a pathophysiologic point of view, the study of the NK peripheral blood cells (Leu 11/CD16) suggests the existence of two kinds of RAS-patients: those showing normal NK cell numbers (approximately 33%) and those ones showing a partial lack in the NK numbers (approximately 67%). These results suggest different rational new approaches to treatment, based on new pathophysiological concepts.

journal_name

Rev Clin Esp

journal_title

Revista clinica espanola

authors

Camacho F,Elorza FL,Ortega M,Elorza MA,Sada G,Villarrubia VG

subject

Has Abstract

pub_date

1991-05-01 00:00:00

pages

403-8

issue

8

eissn

0014-2565

issn

1578-1860

journal_volume

188

pub_type

临床试验,杂志文章
  • [Underestimation of energy intake in a group of young female university students of Madrid].

    abstract::The validity of estimates of energy intake in a group of young women, and the influence of body mass index (BMI) and concern over bodyweight on such estimates, were determined with the aid of a food record intake. The study subjects were a group of female university students between 20 and 32 years of age. Participant...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:

    authors: Ortega Anta RM,Quintas Herrero E,Sánchez Quiles B,Andrés Carvajales P,Requejo Marcos AM,Encinas Sotillos A

    更新日期:1997-08-01 00:00:00

  • Medical treatment of type 2 diabetes mellitus: Recommendations of the Diabetes, Obesity and Nutrition Group of the Spanish Society of Internal Medicine.

    abstract::Type 2 diabetes mellitus is a major health problem with high prevalence, morbidity and mortality, and its medical treatment is growing in complexity due to patients' diverse clinical conditions. This article presents a consensus document by the Diabetes, Obesity and Nutrition Group of the Spanish Society of Internal M...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:10.1016/j.rce.2020.06.005

    authors: Carrasco-Sánchez FJ,Fernández-Rodríguez JM,Ena J,Gómez-Huelgas R,Carretero-Gómez J,en representación del Grupo de trabajo de Diabetes, Obesidad y Nutrición de la Sociedad Española de Medicina Interna.

    更新日期:2020-07-13 00:00:00

  • [Report of the editors, 2011].

    abstract::The editors of Revista Clínica Española (Rev Clin Esp) inform on their editorial activity during the last 12 months (November 2010 to October 2011): (a) Objectives and attainments during 2011, (b) editorial activity, and (c) objectives for 2012. In 2011 we have updated the editorial algorithm (revision by the responsi...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:10.1016/j.rce.2011.11.004

    authors: García Puig J,Gaspar Alonso-Vega G,Ríos Blanco JJ

    更新日期:2012-01-01 00:00:00

  • [Respiratory infection caused by Pseudomonas aeruginosa in patients with HIV infection].

    abstract:OBJECTIVE:Descriptive study of severe respiratory infections caused by Pseudomonas aeruginosa in patients with HIV infection. METHODS:Review of clinical records of HIV-positive patients admitted in a tertiary hospital from 1-1-1990 to 9-30-1995. The patients included in this study were those with P. aeruginosa recover...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:

    authors: Arrizabalaga Aguirreazaldegui J,Horcajada Gallego JP,Mentxaka Ugalde B,Rodríguez Arrondo F,Iribarren Loyarte JA,von Wichman de Miguel M,Garde Orbaiz C

    更新日期:1996-10-01 00:00:00

  • [Tularemia outbreak in the province of Cuenca associated with crab handling].

    abstract:OBJECTIVE:To report the clinical and epidemiologic characteristics of 19 patients diagnosed of tularemia at our hospital following an epidemic outbreak occurred in our health area. METHODS:Retrospective analysis of clinical records of patients admitted to our hospital who were examined at the Infectious Diseases Clini...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:10.1016/s0014-2565(01)70854-5

    authors: Díaz de Tuesta AM,Chow-Quan,Geijo Martínez MP,Dimas Núñez J,Díaz de Tuesta FJ,Herranz CR,Val Pérez E

    更新日期:2001-07-01 00:00:00

  • Norton scale score on admission and mortality of patients hospitalised in Internal Medicine departments.

    abstract:OBJECTIVE:To determine the association between the Norton scale score (which assesses the risk of pressure ulcers) and mortality in the short, medium and long term in patients hospitalised in Internal Medicine departments. PATIENTS AND METHODS:A prospective, single-centre cohort study was conducted on patients hospita...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:10.1016/j.rce.2018.02.009

    authors: Díez-Manglano J,Arnal-Longares MJ,Al-Cheikh-Felices P,Garcés-Horna V,Pueyo-Tejedor P,Martínez-Rodés P,Díez-Massó F,Rubio-Félix S,Del Corral-Beamonte E,Palazón-Fraile C,en representación de los investigadores del estudio IMPIMI.

    更新日期:2018-05-01 00:00:00

  • [Internal Medicine hospital departments of Andalucian Public Health System. A description of the clinical activity in 2002].

    abstract:BACKGROUND:Description of the patients admitted in the general Internal Medicine (IM) departments of the Public Health System in Andalusia (Spain) (PHSA) during 2002. PATIENTS AND METHODS:It is an analysis of the Minimum Basic Set of Data (MBSD) and its management by the Diagnostic Related Groups (DRG) of admission ep...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:10.1157/13084760

    authors: de San Román y de Terán CM,Guijarro Merino R

    更新日期:2006-01-01 00:00:00

  • [Pancreatic changes associated with acute gastroenteritis].

    abstract::A retrospective study is discussed, in which the disorder of pancreatic enzymes in hospitalized patients because of an acute infectious gastroenteritis is analyzed. Of 30 cases, 15 showed a raise in lipase levels, being over 1,000 IU in five of them. There was no associated raise in amylase levels. Patients with high ...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:

    authors: Poza JJ,Amato E,Mentxaka B

    更新日期:1992-10-01 00:00:00

  • [Should we use oral replacement for vitamin B12 deficiency as the first option of treatment?].

    abstract:OBJECTIVE:Analyze whether the tablets available in Spain are useful for oral replacement in the treatment of vitamin B12 deficiency. METHODS:From June 2003 to December 2005, patients with vitamin B12 deficiency attended at the Internal Medicine Clinic, were offered the possibility of starting or switching to oral ther...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:10.1157/13101846

    authors: Rabuñal Rey R,Monte Secades R,Peña Zemsch M,Bal Alvaredo M,Gómez Gigirey A

    更新日期:2007-04-01 00:00:00

  • [ACTH-independent Cushing's syndrome due to bilateral macronodular adrenal hyperplasia with empty sella turcica and anterior panhypopituitarism].

    abstract::A case is presented of Cushing's syndrome due to macronodular bilateral adrenal hyperplasia which is ACTH-independent as was demonstrated by the undetectable basal and after stimulation with metoprolol ACTH plasma levels. High cortisol levels is associated in this patient with empty sella turcica and anterior panhypop...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:

    authors: Menéndez Torre EL,López Carballo MT,Rodríguez Erdozain R,Urbieta Echezarreta M,Lafita Tejedor J,Forga Llenas L

    更新日期:1992-03-01 00:00:00

  • [Clinical characteristics of arterial hypertension in the elderly].

    abstract::The clinical characteristics of systolic and diastolic hypertension in 75 and of systolic hypertension in 50 elderly patients have been studied and the results have been compared to those obtained in 23 normotense elderly controls and 500 young patients with essential hypertension. A greater incidence in cardiovascula...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:

    authors: Puras A,Alcázar JM,Miranda B,Oliet A,Rodicio JL,Ruilope LM

    更新日期:1989-06-01 00:00:00

  • [Study of costs associated with catheter-related bacteremia].

    abstract:BACKGROUND:Nosocomial infection (NI) is associated with an increase in resource consumption. The estimation of extra costs attributable to NI in a group of patients with catheter-related bacteremia (CRB) was the objective of the present study. METHODS:A matched case-control, study was conducted in a cohort population....

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:

    authors: Morís de la Tassa J,Fernández Muñoz P,Antuña Egocheaga A,Gutiérrez del Río MC,de la Fuente García B,Cartón Sánchez JA

    更新日期:1998-10-01 00:00:00

  • [A clinico-epidemiological study of leptospirosis in adults in the province of Ciego de Avila].

    abstract::A clinical epidemiological study of reported leptospirosis cases in adults in the period 1984-1988 in the province Ciego de Avila, Republic of Cuba, was conducted. The most frequent symptoms and signs were: fever, headache and arthralgia. Eighty-two percent of patient were anicteric. The most frequent presumptive diag...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:

    authors: Suárez Hernández M,Santisteban Mota R,Cabrera Cabrera J,del Risco Alard,Pelaéz Martínez R

    更新日期:1995-07-01 00:00:00

  • [The diagnostic usefulness of cholinesterase in pleural exudates].

    abstract:BACKGROUND AND OBJECTIVES:The pleural fluid/serum cholinesterase ratio (PF/S) is the most efficient parameter to differentiate transudates from exudates. The objective of this study was to evaluate whether its determination might yield additional diagnostic information in pleural exudates. MATERIALS AND METHODS:A tota...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:

    authors: García Pachón E,Padilla Navas I

    更新日期:1997-06-01 00:00:00

  • Tp-e interval and Tp-e/QT ratio in patients with celiac disease.

    abstract:OBJECTIVES:Celiac disease is a chronic immune-mediated disease of the small intestine. It has been known that dilated cardiomyopathy and ischemic coronary artery disease have become more frequent in patients with celiac disease. The aim of the study was to assess Tp-e interval and Tp-e/QT ratio in patients with celiac ...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:10.1016/j.rce.2017.09.001

    authors: Demirtaş K,Yayla Ç,Yüksel M,Açar B,Ünal S,Ertem AG,Kaplan M,Akpinar MY,Kiliç ZMY,Kayaçetin E

    更新日期:2017-11-01 00:00:00

  • Aortic stenosis. Indications and results of percutaneous aortic valve implantation (TAVI).

    abstract::Aortic stenosis (AS) is the most common valvular heart disease in developed countries. Its prevalence increases progressively due the aging of the population. Transcatheter aortic valve implantation (TAVI), however, has revolutionised the treatment of AS. With the current data, we can confirm that TAVI is the treatmen...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:10.1016/j.rce.2017.05.001

    authors: Salido Tahoces L,Hernández Antolín RA,Zamorano Gómez JL

    更新日期:2017-11-01 00:00:00

  • [Muscular tumors of the digestive tract: an analysis of 53 cases].

    abstract::We present 53 cases of gastrointestinal smooth tumors (43 leiomyomas and 10 leiomyosarcomas) which have being diagnosed in Virgen del Camino Hospital during a period of 17 years. The aim of the research is to know the incidence of such tumors, their clinical presentation, the usefulness of radiologic and endoscopic st...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章,评审

    doi:

    authors: Larequi A,Jiménez C,Aizcorbe M,Almudévar E,Iglesias R,Metola L,Mendoza H

    更新日期:1995-12-01 00:00:00

  • [Prevalence of vertebral fractures in hip fracture patients].

    abstract:BACKGROUND:Fractures are the clinical complication of osteoporosis. There are no previous studies that describe the prevalence of vertebral fractures (VF) in patients admitted into a hospital due to a hip fracture (HF). OBJECTIVE:To study the prevalence of vertebral fractures in elderly women in the moment of their ad...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章,多中心研究

    doi:10.1157/13109839

    authors: Sosa Henríquez M,Saavedra Santana P,grupo de trabajo en osteoporosis de la Sociedad Española de Medicina Interna (SEMI).

    更新日期:2007-10-01 00:00:00

  • [Hereditary hemorrhagic telangiectasia at an internal medicine service: study of 12 patients].

    abstract::Hereditary hemorrhagic telangiectasia (HHT) is a hereditary dominant autosoma clinical entity characterized by repeated hemorrhages (being epistaxis the more frequent) and telangiectasia in skin, mucosa and internal organs. Incidence in Europe is 1,2 per 100,000 pop. We discuss the experience of an Internal Medicine D...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:

    authors: Cabañes Argudo M,Villar Grimalt A,Puche Azorín P,Franco Serrano J,Brotons Brotons B

    更新日期:1992-10-01 00:00:00

  • [Predictive factors of non-compliance with anti-tuberculosis treatment in patients infected with the human immunodeficiency virus].

    abstract::A study was conducted to know the rate of non-compliance of antituberculosis therapy among HIV-infected patients, the factors associated with non-compliance and the evolution of these patients. The therapy compliance in 276 tuberculous HIV infected patients diagnosed in two Madrid hospitals was analyzed. Fifty-one pat...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:

    authors: Pulido Ortega F,Sánchez de Rivera JM,Rubio García R,González García J,Costa Pérez-Herrero JR,Vázquez Rodríguez JJ,del Palacio Pérez-Medel A

    更新日期:1997-03-01 00:00:00

  • [Biological markers of alcoholism].

    abstract::Diagnosis of alcoholism is very important, given its high prevalence and possibility of influencing the disease course. For this reason, the so-called biological markers of alcoholism are useful. These are analytic parameters that alter in the presence of excessive alcohol consumption. The two most relevant markers ar...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:10.1157/13079074

    authors: Marcos Martín M,Pastor Encinas I,Laso Guzmán FJ

    更新日期:2005-09-01 00:00:00

  • [Socioeconomic effects of human brucellosis].

    abstract::The socio-economic cost of human brucellosis is analyzed. One hundred and seven patients are included in this study, 75 males (70.09%) and 32 females (29.91), diagnosed of brucellosis in the Internal Medicine Department of the Regional Hospital "Carlos Haya" in Málaga from the 1st of October 1984 to the 31st of Decemb...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:

    authors: Colmenero Castillo JD,Cabrera Franquelo FP,Hernández Márquez S,Reguera Iglesias JM,Pinedo Sánchez A,Castillo Clavero AM

    更新日期:1989-12-01 00:00:00

  • [Graves Basedow disease following treatment with magistral formulae for obesity. Jod-Basedow phenomenon?].

    abstract::Two cases are reported of women aged 18 and 36 years respectively who developed a typical picture of hyperthyroidism by Graves Basedow disease (primary hyperthyroidism, diffuse goiter with increased uptake, positive stimulating thyroid antibodies, exophthalmos). These women had taken drugs for obesity which were prepa...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:

    authors: Goday-Arnó A,García Rico A,Martínez-Riquelme A,Cano-Pérez JF

    更新日期:1996-08-01 00:00:00

  • [Renal failure secondary to diabetic nephropathy. A review of the characteristics of the diabetic patients who started dialysis in Catalonia in 1994].

    abstract::The appearance of diabetic nephropathy and its progression towards renal failure can be prevented if an early treatment is instituted. However, diabetes is currently one of the main causes of entry into a dialysis program. Therefore, the diagnostic characteristics of renal disease in 105 patients who started dialysis ...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:

    authors: González MT,Castell C,Esmatjes E,Tresserras R,de Lara N,Lloveras G

    更新日期:1999-01-01 00:00:00

  • [The presence of oligoclonal bands in the cerebrospinal fluid in various neurologic diseases].

    abstract::The polyacrylamide gel electrophoresis of spinal fluid from 488 patients suffering neurological diseases and from a control group are reviewed. One hundred and eleven cases (22.7%) showed oligoclonal bands (OB). The highest percentage of OB appeared in the group of patients with definite multiple sclerosis (84%), foll...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:

    authors: Coret F,Vílchez JJ,Enguídanos MJ,López-Arlandis J,Fernández-Izquierdo S

    更新日期:1989-10-01 00:00:00

  • [Alterations in osmoregulation in the elderly].

    abstract::In the present work we study the modifications in hydrosaline metabolism which occurred in two groups of healthy male individuals, one consisting of 15 young men (mean age of 20 years) and the other of 30 elderly subjects (mean age of 75 years) when the thirst test was performed for 48 hours. After performing the thir...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:

    authors: Jiménez Bravo de Laguna S,Sosa Henríquez M,Limiñana Cañal JM,Font de Mora Turón A,Viqueras Pérez JF,Betancor León P

    更新日期:1991-07-01 00:00:00

  • Unnecessary overuse. Study of "inadvisable practices" for patients with atrial fibrillation.

    abstract:OBJECTIVE:To identify overuse (diagnostic, therapeutic and self-care practices that represent risks that outweigh the potential benefits) in patients with atrial fibrillation. METHOD:The study was based on qualitative research techniques. Using the "Metaplan" technique, we identified and ordered potentially inappropri...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:10.1016/j.rce.2017.02.014

    authors: Ortiz MM,Llamas P,Sanmartín M,Egido JA,Del Toro J,Egocheaga MI,Estévez MS,Navarro IM,Mira JJ

    更新日期:2017-05-01 00:00:00

  • [Self-care behavior and patients' knowledge about self-care predict rehospitalization among older adults with heart failure].

    abstract:INTRODUCTION:This study examined the association of self-care behavior and patients' knowledge about self-care with rehospitalization among older adults with heart failure (HF). METHODS:Case-control comparison (116 cases and 209 controls) nested in a prospective cohort of patients aged 65 years and older admitted for ...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:10.1157/13123185

    authors: Rodríguez Artalejo F,Guallar-Castillón P,Montoto Otero C,Conde Herrera M,Carreño Ochoa C,Tabuenca Martín AI,Olcoz Chiva M,Conthe P,Banegas JR,Rodríguez Pascual C

    更新日期:2008-06-01 00:00:00

  • [Polymicrobial endocarditis: a clinical and evolutive study of 12 cases diagnosed during a 10-year period].

    abstract::Polymicrobial endocarditis (PE) is uncommon, whether in series of cases of polymicrobial bacteriemia or of endocarditis. Among the 201 cases of infective endocarditis seen between 1986 and 1995 by an infectious diseases service, 12 patients had PE (6%). Nine were males, mean age was 28 years and ten were active intrav...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:

    authors: Valencia Ortega ME,Enríquez Crego A,Guinea Esquerdo J,González Lahoz J

    更新日期:1997-04-01 00:00:00

  • [Stroke in the hands of the internist. Cardiovascular risk factors].

    abstract:INTRODUCTION:This study has aimed to describe cardiovascular risk factors (CVRF) associated to stroke and their detection and monitoring during the acute episode and the recommendations on hospital discharge. The hypothesis was to check if the integral care of the internist improved the care to these patients. MATERIA...

    journal_title:Revista clinica espanola

    pub_type: 杂志文章

    doi:10.1157/13124313

    authors: Sanclemente Ansó C,Pedragosa Vall A,Rovira Pujol E,Vigil Martín D

    更新日期:2008-07-01 00:00:00