Abstract:
OBJECTIVES:To assess the cost-effectiveness of a nucleic acid amplification test (FluoroType MTB®) in pleural fluid (PF) and sputum to diagnose tuberculous pleural effusion (TPE). We also analysed the increase in diagnostic yield of a second FluoroType MTB® test, obtained through a new thoracentesis, when the first had resulted negative. METHODS:We conducted a prospective single-centre study that included 207 patients with pleural effusion (31 tuberculous and 176 from other causes). Of the 31 cases of TPE, 21 (68%) were confirmed histologically or microbiologically; the other cases were considered probable. RESULTS:The operational characteristics of FluoroType MTB® in PF for identifying tuberculosis were a sensitivity of 13%, a specificity of 99%, a positive likelihood ratio of 11 and a negative likelihood ratio of 0.9. The diagnostic efficacy data for sputum samples was 21%, 91%, 2.4 and 0.9, respectively. The PF and sputum cultures in solid and liquid media had greater sensitivity (36% and 31%, respectively). A second FluoroType MTB® test in PF was negative for 24 patients with TPE, and a first FluoroType MTB® test also negative. Only 2 (6.5%) patients with TPE had a confirmed diagnosis based exclusively on the positive results of the FluoroType MTB® in PF. CONCLUSION:Due to its low sensitivity, the FluoroType MTB® test in PF has a limited role in diagnosing tuberculous pleurisy.
journal_name
Rev Clin Espjournal_title
Revista clinica espanolaauthors
Bielsa S,Bernet A,Civit C,Acosta C,Manonelles A,Porcel JMdoi
10.1016/j.rce.2020.04.010subject
Has Abstractpub_date
2020-06-01 00:00:00eissn
0014-2565issn
1578-1860pii
S0014-2565(20)30119-3pub_type
杂志文章abstract::The epithelial neoplasias associated to monoclonal gammapathy (GM) seen in a general hospital over a period of six years are reviewed. 8 cases were detected, 2 of which behaved as a second neoplasia since they occurred in patients previously diagnosed of multiple myeloma. The incidence and characteristics of the monoc...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:
更新日期:1989-10-01 00:00:00
abstract::We here present the case of a patient who starts with a progressive vision loss, observing in the radiologic exam herniation of optic chiasma in a primary empty sella turcica. Based on this case, we have performed a review of this clinical picture and point out the most important aspects in the literature. ...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:
更新日期:1991-04-01 00:00:00
abstract:INTRODUCTION:Geographic tongue (GT) is a lesion of unknown origin associated with systemic diseases and therefore involves multidisciplinary care. METHODS:We performed a literature search of the PubMed, EMBASE, Web of Science and Cochrane databases. The selection criteria were consistent with the Preferred Reporting I...
journal_title:Revista clinica espanola
pub_type: 杂志文章,评审
doi:10.1016/j.rce.2018.05.006
更新日期:2018-12-01 00:00:00
abstract:OBJECTIVE:To study the prevalence and presentation forms of hereditary hemorrhagic telangiectasia (HHT) among the population in our hospital area. MATERIALS AND METHODS:Descriptive, retrospective study of patients with the diagnosis of HHT from to 1999 at La Fe Hospital, Valencia. Family history, repeated epistaxis, m...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:10.1016/s0014-2565(01)70935-6
更新日期:2001-11-01 00:00:00
abstract:OBJECTIVES:To perform a situation analysis of the care provided by internal medicine units (IMUs) in Spain and to develop, based on this analysis, proposals for improving the quality of care in these units. MATERIAL AND METHODS:A descriptive, cross-sectional study of the IMUs of general acute care hospitals of the Spa...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:10.1016/j.rce.2016.01.002
更新日期:2016-05-01 00:00:00
abstract::In the present work we study the modifications in hydrosaline metabolism which occurred in two groups of healthy male individuals, one consisting of 15 young men (mean age of 20 years) and the other of 30 elderly subjects (mean age of 75 years) when the thirst test was performed for 48 hours. After performing the thir...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:
更新日期:1991-07-01 00:00:00
abstract:OBJECTIVE:Although the genetic component in colorectal carcinoma (CRC) is well established, some environmental factors, mainly dietary, can favor its development. The objective of this study is to evaluate the relationship between daily consumption of specific food groups and development of CRC. METHODS:We carried out...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:10.1157/13063526
更新日期:2004-07-01 00:00:00
abstract:OBJECTIVE:Our objective was that of describing a series of episodes of upper limb deep venous thrombosis, with special emphasis on the incidence of posthrombotic syndrome and its impact in the quality of life of the patients. METHODS:33 episodes (29 patients) of upper limb deep venous thrombosis were studied, between ...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:10.1157/13070751
更新日期:2005-01-01 00:00:00
abstract::Type 2 diabetes mellitus is a major health problem with high prevalence, morbidity and mortality, and its medical treatment is growing in complexity due to patients' diverse clinical conditions. This article presents a consensus document by the Diabetes, Obesity and Nutrition Group of the Spanish Society of Internal M...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:10.1016/j.rce.2020.06.005
更新日期:2020-07-13 00:00:00
abstract::Cutaneous larva migrans (CLM) is a frequent dermal disease in travelers, caused by larvae of nonhuman ancylostoma. We describe 34 outside cases of CLM diagnosed since January 1991 to June 2002. Nineteen male and female. Age: 35.7 years (20-60). The total number of CLM infestations was 73, 83.5% in feet. In five cases ...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:10.1016/s0014-2565(04)71567-2
更新日期:2004-12-01 00:00:00
abstract::Our objective has been to elaborate an updated Clinical Guide of the Spanish Society of Internal Medicine (SEMI) for the prevention and treatment of glucocorticoids-induced osteoporosis (GIO), identifying and measuring the grade of evidence that supports the given recommendations. For this, we reviewed studies perform...
journal_title:Revista clinica espanola
pub_type: 杂志文章,实务指引
doi:10.1157/13115006
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVES:To assess the routine indication of chest roentgenogram after thoracentesis in function of iatrogenic pneumothorax causation, following a procedure protocol. PATIENTS AND METHODS:Prospective study of 104 consecutive thoracentesis procedures performed in 76 patients. The procedure was protocolized and after ...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:10.1157/13044921
更新日期:2003-03-01 00:00:00
abstract::Liver transplant is the first therapeutic choice in most of the advanced liver diseases. Nevertheless, its performance originates a number of complications derived from: a) conservation techniques of the organ (in our study a prolonged time of hot ischemia was significantly associated with); b) surgery (all patients w...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:
更新日期:1991-10-01 00:00:00
abstract::Results of clinical studies are contradictories, with different results in adults and children. Some studies detected a beneficial effect of Omega 3 (w3) fatty acid dietary intake in the risk of asthma and other studies have demonstrated a beneficial effect on clinical symptoms. In our area, a low intake of w3 fatty a...
journal_title:Revista clinica espanola
pub_type: 杂志文章,评审
doi:10.1157/13098496
更新日期:2007-01-01 00:00:00
abstract::BACKGROUND. In 1997, The Fourth International Workshop-Conference on Gestational Diabetes Mellitus (GDM) recommended the use of Carpenter and Coustan diagnostic criteria instead of those of Sullivan and Mahan used until then. The objective of this work was to study the incidence of GDM in the southeast Madrid area by ...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:10.1016/s0014-2565(02)71008-4
更新日期:2002-03-01 00:00:00
abstract:OBJECTIVES:To know the frequency of antibiotic prescription, the conditions that motivate their usage, and to evaluate the quality of such therapies in a hospital emergency department (HED). METHODS:Retrospective study of 2,677 patients attended at a HED for a one-month period including those who had antibiotics presc...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:
更新日期:1996-07-01 00:00:00
abstract::Anisakis simplex is a nematode which parasitizes mainly fish and cephalopods and accidentally human beings after ingestion. Apart from the different digestive syndromes, this organism has recently been involved as cause of IgE-mediated allergic reactions of variable degree (urticaria to severe angioedema). In this rep...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:
更新日期:1998-09-01 00:00:00
abstract::Without a doubt blood pressure autoevaluation facilitates hypertension diagnosis, control and treatment. This also helps research, makes possible costs reduction and is an easy, safe, and useful method. Its use should be favored in the new model of patient-based clinical practice. ...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:10.1157/13072969
更新日期:2005-03-01 00:00:00
abstract::Viral replication seric markers (VRSM), (BeHAg, BcHAg, and DNA-VHB) and the hepatic tissue BcHAg of thirty four patients suffering from chronic hepatopathies (6 PCH, 18 ACH, and 10 cirrhosis) were investigated. The greatest incidence of RVSM was observed in PCH. The combined study using all the markers demonstrated a ...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:
更新日期:1991-03-01 00:00:00
abstract::We have screened a population of newborn babies without any previous apparent pathology in order to discover the distribution of alpha 1-anti-trypsin phenotypes (AAT) in our community. The research has been done on 457 babies born in the province of Valladolid, determining the plasma levels of AAT and the correspondin...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:
更新日期:1989-02-01 00:00:00
abstract::The name fetus-in-fetu designates the presence of a tumoral mass containing a homunculus. Fewer than 70 cases have been reported in the literature since its first description about 1800. This entity usually presents in childhood and it is exceptional in adult life. There is an interesting debate regarding its origin a...
journal_title:Revista clinica espanola
pub_type: 杂志文章,评审
doi:
更新日期:1996-11-01 00:00:00
abstract::Chronic obstructive pulmonary disease (COPD) encompasses a group of diseases characterized by chronic airway obstruction. This broad diagnostic umbrella includes several clinical phenotypes that overlap and respond differently to each type of therapeutic intervention. Roflumilast is a drug belonging to the new therape...
journal_title:Revista clinica espanola
pub_type: 杂志文章,评审
doi:10.1016/S0014-2565(11)70008-X
更新日期:2011-03-01 00:00:00
abstract::Aortic stenosis (AS) is the most common valvular heart disease in developed countries. Its prevalence increases progressively due the aging of the population. Transcatheter aortic valve implantation (TAVI), however, has revolutionised the treatment of AS. With the current data, we can confirm that TAVI is the treatmen...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:10.1016/j.rce.2017.05.001
更新日期:2017-11-01 00:00:00
abstract::Ogilvie's syndrome (OS) is a clinical condiction with the symptoms, signs and radiological appearances of acute bowell obstruction but without any apparent mechanical cause. Diagnosis and treatment are often delayed and many patients are still inappropriately managed which in turn results in an increase in morbidity a...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:
更新日期:1995-11-01 00:00:00
abstract:OBJECTIVES:To analyze the effect of a global approach on patients with high cardiovascular risk for the integral control of cardiovascular risk factors. PATIENTS AND METHODS:Multicentric prospective study of patients with high vascular risk, followed-up for one year in internal medicine consultations. We measured the ...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:10.1157/13100222
更新日期:2007-03-01 00:00:00
abstract:OBJECTIVE:To determine the appearance of type 2 diabetes mellitus (DM2) and impaired fasting glucose (IFG) at five years of follow-up in a known non-diabetic population. PATIENTS AND METHODS: DESIGN:nested case control studies (case s-control into a cohort) developed in two stages: 1) identification and characterizat...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:10.1016/s0014-2565(09)70351-0
更新日期:2009-01-01 00:00:00
abstract::The use of ambulatory monitorization of blood pressure has shown the importance of the alarm reaction or white coat reaction and its conditioning factors in some patients. The influence of place (medical facility or home) and person who performs the procedure (doctor or nurse) on the taking of blood pressure is studie...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:
更新日期:1994-03-01 00:00:00
abstract::A study was conducted to know the rate of non-compliance of antituberculosis therapy among HIV-infected patients, the factors associated with non-compliance and the evolution of these patients. The therapy compliance in 276 tuberculous HIV infected patients diagnosed in two Madrid hospitals was analyzed. Fifty-one pat...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:
更新日期:1997-03-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to determine the prognostic factors in relationship to evolution to death of bacteremia-fungemia (BF) episodes occurred in 1986 and to compare them with the results obtained ten years later in 1996. PATIENTS AND METHODS:Prospective study of all BF episodes observed at Hospital...
journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:10.1016/s0014-2565(01)70765-5
更新日期:2001-03-01 00:00:00
abstract:BACKGROUND:Fractures are the clinical complication of osteoporosis. There are no previous studies that describe the prevalence of vertebral fractures (VF) in patients admitted into a hospital due to a hip fracture (HF). OBJECTIVE:To study the prevalence of vertebral fractures in elderly women in the moment of their ad...
journal_title:Revista clinica espanola
pub_type: 杂志文章,多中心研究
doi:10.1157/13109839
更新日期:2007-10-01 00:00:00