Abstract：
:Microelectrode recordings were made from dorsal column postsynaptic (DCPS) fibres, in the fasciculus gracilis of the cat, at thoracic level Th 12, and from single cells in the nucleus gracilis. The sensitivity of the fibres (Th 12) and cells (bulbar level) to both gentle and noxious stimuli was studied and a classification of the units was made on the basis of their responses to these natural stimuli. The DCPS fibres have been classified into three groups: i) 16.3% of them were activated only by light mechanical stimuli, ii) a few responded to nothing but noxious mechanical stimuli, iii) 77% were characterized by their sensitivity to both gentle and noxious stimuli and constituted the polymodal group. The study of the nucleus gracilis cells revealed that 31.2% of the total number of cells investigated in the nucleus were also characterized by a high degree of modality convergence (polymodal cells). Besides their convergence, the polymodal DCPS fibres and the polymodal cells of the nucleus gracilis were functionally in contrast to the properties of the specific fibres and cells of the dorsal column system in other respects: i) they responded with a slowly adapting response to constant mechanical stimulation of the skin, ii) they were sensitive to noxious mechanical and thermal stimuli. It is argued that the polymodal cells could be the bulbar relay of the impulses conveyed through the DCPS fibres of the fasciculus gracilis. The possible role of the dorsal column system in nociception is discussed in the light of the results.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Angaut-Petit Ddoi
10.1007/BF00237349keywords:
subject
Has Abstractpub_date
1975-05-22 00:00:00pages
471-93issue
5eissn
0014-4819issn
1432-1106journal_volume
22pub_type
杂志文章abstract：:Though previous studies have suggested that the basal ganglia are necessarily involved in action imitation, their precise role is unclear. An important source of evidence concerns patients with Parkinson's disease (PD) who suffer basal ganglia impairments. Some studies report poor execution of observed meaningful (MF)...
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