Abstract:
:In literature, cases of nutmeg abuse have been described repeatedly, but only one fatal case of poisoning was reported [1]. In the present case, myristicin (4 microg/ml) was detected for the first time in the postmortal serum of a 55-year-old woman. Identification was achieved with the aid of UV-VIS spectroscopy and TLC; for quantification, HPLC was used. Because also flunitrazepam (0.072 microg/ml) was found, death had probably been due to the combined toxic effect of both substances. From 1996 to 1998, in a series of cases, seven poisonings with nutmeg were recorded by the Erfurt Poison Information Centre. Even where higher doses (20-80 g of powder) had been ingested, a life-threatening situation was never observed. In one of these cases, a myristicin blood level of 2 microg/ml was measured 8h after ingestion of two to three tablespoonful of nutmeg powder (approx. 14-21 g, or 280-420 mg/kg).
journal_name
Forensic Sci Intjournal_title
Forensic science internationalauthors
Stein U,Greyer H,Hentschel Hdoi
10.1016/s0379-0738(00)00369-8keywords:
subject
Has Abstractpub_date
2001-04-15 00:00:00pages
87-90issue
1eissn
0379-0738issn
1872-6283pii
S0379073800003698journal_volume
118pub_type
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