Abstract:
RATIONALE AND OBJECTIVES:The purpose of this study was to evaluate the accuracy of ultrasound (US)-guided fine-needle aspiration (FNA), with radiographic follow-up or surgical excision, in conjunction with on-site cytopathologic support in the management of nonpalpable breast lesions. MATERIALS AND METHODS:The findings of 266 consecutive mammographically or sonographically identified, nonpalpable lesions (228 patients) that underwent US-guided FNA were examined retrospectively. Clustered microcalcifications did not undergo biopsy with this method. Patients who underwent follow-up excisional biopsy or mammography with a duration of at least 24 months were included in the study. RESULTS:In all, 117 lesions met criteria for inclusion, of which 85 (73%) were diagnosed as benign at cytopathologic evaluation and underwent mammographic follow-up of at least 24 months (range, 24-67 months; mean, 36 months). Thirty-two lesions (27%) had either malignant or atypical cytopathologic findings, for which surgery was recommended. Eleven (9%) of the 32 had malignant cytopathologic findings from initial US-guided FNA, which were confirmed at surgical excision. The remaining 21 lesions (18%) were diagnosed as atypical on the basis of US-guided FNA results. Of these, 18 lesions underwent excisional biopsy: Two were diagnosed as carcinoma (not otherwise specified), and 16 were diagnosed with a variety of benign disorders. The remaining three patients with atypical lesions chose mammographic follow-up rather than surgical diagnosis, and their conditions have remained stable for more than 24 months. Of the 85 benign cases, one changed during follow-up (12 months) and underwent repeat biopsy, with malignancy noted. The sensitivity of US-guided FNA in identifying malignant lesions was 93% (13 of 14), and the specificity of a benign finding was 100% (102 of 102). The positive and negative predictive values of US-guided FNA supported by on-site cytopathologic evaluation were 100% (13 of 13) and 99% (102 of 103), respectively. CONCLUSION:Supported by appropriately trained on-site cytopathologists and in conjunction with follow-up mammography, US-guided FNA appears to be efficacious in the management of patients with abnormal radiographic findings. It is quick, relatively inexpensive, and minimally invasive, and, in the presence of competent cytopathologists, should be the modality of choice.
journal_name
Acad Radioljournal_title
Academic radiologyauthors
Buchbinder SS,Gurell DS,Tarlow MM,Salvatore M,Suhrland MJ,Kader Kdoi
10.1016/S1076-6332(03)80501-9keywords:
subject
Has Abstractpub_date
2001-04-01 00:00:00pages
322-7issue
4eissn
1076-6332issn
1878-4046pii
S1076-6332(03)80501-9journal_volume
8pub_type
杂志文章abstract:RATIONALE AND OBJECTIVES:Pathogenic mutations in some genes elevate women's breast cancer risk, necessitating risk-reduction strategies. Unfortunately, women are underscreened for cancer risk, and when identified as potentially high risk, women seldom pursue genetic counseling or testing. To improve cancer risk managem...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2020.12.005
更新日期:2020-12-15 00:00:00
abstract:RATIONALE AND OBJECTIVES:Breast cancer is the leading type of cancer among women. Visualization and characterization of breast lesions based on vascularity kinetics was evaluated using three-dimensional (3D) contrast-enhanced ultrasound imaging in a clinical study. MATERIALS AND METHODS:Breast lesions (n = 219) were i...
journal_title:Academic radiology
pub_type: 杂志文章,多中心研究
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更新日期:2020-08-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The authors performed this study to evaluate whether digitally photographed, computer-annotated MR images produced by clinical radiologists and printed with an inexpensive photo printer are suitable for publication. MATERIALS AND METHODS:Laser prints of 20 magnetic resonance images of the brai...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(03)80378-1
更新日期:2002-03-01 00:00:00
abstract:RATIONALE AND OBJECTIVE:Targeted delivery is a highly desirable strategy for diagnostic imaging because of enhanced efficacy and reduced dosage/toxicity. Receptor-targeting was used to deliver contrast-producing superparamagnetic iron oxide (IO) nanoparticle to receptor-expressing tumors for in vivo magnetic resonance ...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2004.04.018
更新日期:2004-09-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:We analyzed multi-institutional data to determine if Step 3 performance tiers can identify radiology residents with increased risk of Core examination failure and submean performance. MATERIALS AND METHODS:We collected Step 3 scores (USMLE Step 3 or COMLEX Level 3) and American Board of Radiol...
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pub_type: 杂志文章
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更新日期:2020-08-06 00:00:00
abstract:RATIONALE AND OBJECTIVES:The authors compared magnetic resonance (MR) image quality obtained from 3- and 1-mm-thick sections in the depiction of the temporomandibular joint (TMJ) and its adjacent structures. MATERIALS AND METHODS:Eight TMJ specimens from four adult cadaver heads were depicted with MR imaging. Both 3- ...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/S1076-6332(99)80116-0
更新日期:1999-11-01 00:00:00
abstract:RATIONALE AND OBJECTIVE:Abnormal neurodevelopment may play a role in the pathophysiology of schizophrenia. We used deformation-based morphometry to examine voxel-wise age-related changes in patients with schizophrenia compared with healthy brains. MATERIALS AND METHODS:We used a set of skull-stripped brains from an im...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2004.06.009
更新日期:2005-01-01 00:00:00
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journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2007.05.018
更新日期:2007-09-01 00:00:00
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journal_title:Academic radiology
pub_type: 杂志文章
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更新日期:2016-04-01 00:00:00
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journal_title:Academic radiology
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更新日期:2012-02-01 00:00:00
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journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2012.03.004
更新日期:2012-07-01 00:00:00
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journal_title:Academic radiology
pub_type: 杂志文章,评审
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更新日期:2019-05-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To estimate the gain in signal-to-noise ratio (SNR) in first-pass contrast-enhanced (CE) abdominal magnetic resonance angiography (MRA) at 3.0 T compared with 1.5 T. MATERIALS AND METHODS:Three protocols were simulated using six contrast agents: gadopentetate dimeglumine (Magnevist, Berlex, Wa...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2007.03.007
更新日期:2007-07-01 00:00:00
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journal_title:Academic radiology
pub_type: 杂志文章,随机对照试验
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更新日期:2011-06-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To evaluate conspicuity of screen-detected cancers on two-dimensional synthetic mammography (SM) reconstructed from digital breast tomosynthesis (DBT) compared to two-dimensional full field digital mammography (FFDM). MATERIALS AND METHODS:IRB-approved retrospective review of consecutive scree...
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pub_type: 杂志文章
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更新日期:2020-06-01 00:00:00
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journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(96)80223-6
更新日期:1996-07-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To identify magnetic resonance (MR) imaging characteristics allowing specific preoperative discrimination between colloid cysts (CCs) of the sellar region and third ventricle (CC3rdv) versus Rathke's cleft cysts (RCCs). MATERIALS AND METHODS:MR imaging data of 38 patients with histologically p...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2013.08.014
更新日期:2013-11-01 00:00:00
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journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2010.12.009
更新日期:2011-05-01 00:00:00
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journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(98)80226-2
更新日期:1998-04-01 00:00:00
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journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2014.04.013
更新日期:2014-09-01 00:00:00
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journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(96)80448-x
更新日期:1996-03-01 00:00:00
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journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2007.06.014
更新日期:2007-10-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Designed to provide broad-based training in all aspects of imaging, the diagnostic radiology residency program must provide educational experiences that not only provide technical training, but also meet accreditation standards. With the breadth of material to cover during training, carefully o...
journal_title:Academic radiology
pub_type: 杂志文章
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更新日期:2021-01-21 00:00:00
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journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2012.03.007
更新日期:2012-07-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Geometrical distortion is a well-known problem in structural magnetic resonance imaging (MRI), leading to pixel shifts with variations up to several millimeters. Because the main factors of geometrical distortion are proportional to B(0), MRI spatial encoding distortions tend to increase with h...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2011.02.011
更新日期:2011-07-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The aim of this study was to develop a computer-aided diagnosis (CAD) system in assessing the sonographic morphologic and texture features of soft-tissue tumors. MATERIALS AND METHODS:The retrospective study involved 114 pathology proven cases including 73 benign and 41 malignant soft-tissue t...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2009.07.024
更新日期:2009-12-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The American Cancer Society (ACS) and the United States Preventive Services Task Force (USPSTF) recommend colorectal cancer (CRC) screening to begin at age 50 in individuals at average risk for CRC. To estimate rate at which women eligible for CRC screening at the time of screening mammography ...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2004.07.025
更新日期:2004-11-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:This study aimed to determine the appropriate body mass index (BMI)-dependent noise index (NI) setting in computed tomography pulmonary angiography (CTPA) with automatic tube current modulation with adaptive statistical iterative reconstruction (ASiR). MATERIALS AND METHODS:A total of 480 pati...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2016.07.018
更新日期:2016-12-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:This study compared the safety and efficacy of iodixanol with those of ioxaglate in adult patients undergoing aortography or peripheral arteriography. METHODS:Forty-six patients were enrolled in this controlled, randomized, double-blind, two-center study. The patients were monitored for advers...
journal_title:Academic radiology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
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更新日期:1996-09-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Prospective studies of radiologists' interpretations of selected radiographs reported 20-40 years ago indicated error rates of 30% and higher. The authors retrospectively evaluated the interpretations of groups of radiologists and determined a range of rates of disagreement in interpretation. Q...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(98)80277-8
更新日期:1998-03-01 00:00:00