Abstract:
RATIONALE AND OBJECTIVES:Breast cancer is the leading type of cancer among women. Visualization and characterization of breast lesions based on vascularity kinetics was evaluated using three-dimensional (3D) contrast-enhanced ultrasound imaging in a clinical study. MATERIALS AND METHODS:Breast lesions (n = 219) were imaged using power Doppler imaging (PDI), 3D contrast-enhanced harmonic imaging (HI), and 3D contrast-enhanced subharmonic imaging (SHI) with a modified Logiq 9 ultrasound scanner using a 4D10L transducer. Quantitative metrics of vascularity derived from 3D parametric volumes (based on contrast perfusion; PER and area under the curve; AUC) were generated by off-line processing of contrast wash-in and wash-out. Diagnostic accuracy of these quantitative vascular parameters was assessed with biopsy results as the reference standard. RESULTS:Vascularity was observed with PDI in 93 lesions (69 benign and 24 malignant), 3D HI in 8 lesions (5 benign and 3 malignant), and 3D SHI in 83 lesions (58 benign and 25 malignant). Diagnostic accuracy for vascular heterogeneity, PER, and AUC ranged from 0.52 to 0.75, while the best logistical regression model (vascular heterogeneity ratio, central PER, and central AUC) reached 0.90. CONCLUSION:3D SHI successfully detects contrast agent flow in breast lesions and characterization of these lesions based on quantitative measures of vascular heterogeneity and 3D parametric volumes is promising.
journal_name
Acad Radioljournal_title
Academic radiologyauthors
Sridharan A,Eisenbrey JR,Stanczak M,Machado P,Merton DA,Wilkes A,Sevrukov A,Ojeda-Fournier H,Mattrey RF,Wallace K,Forsberg Fdoi
10.1016/j.acra.2019.10.029subject
Has Abstractpub_date
2020-08-01 00:00:00pages
1065-1074issue
8eissn
1076-6332issn
1878-4046pii
S1076-6332(19)30547-1journal_volume
27pub_type
杂志文章,多中心研究abstract:RATIONALE AND OBJECTIVES:To evaluate the reproducibility of Modified Response Evaluation Criteria in Solid Tumors (mRECIST) for hepatocellular carcinoma (HCC) after transarterial chemoembolization (TACE) using multiphasic computed tomography. MATERIALS AND METHODS:The institutional review board approved this retrospec...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2018.02.013
更新日期:2018-11-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:We sought to identify factors associated with high levels of external research funding in order to provide departments with information that may help them increase their external research funding. MATERIALS AND METHODS:National Institutes of Health (NIH) data on grants were analyzed to identif...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2006.09.052
更新日期:2006-12-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:SYNTAX score is a useful metric determined at the time of invasive coronary angiography (ICA) to assess the complexity of coronary artery disease, and improves prediction of complications at the time of percutaneous complex intervention (PCI). We aimed to determine whether SYNTAX score can be r...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2016.07.003
更新日期:2016-11-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Designed to provide broad-based training in all aspects of imaging, the diagnostic radiology residency program must provide educational experiences that not only provide technical training, but also meet accreditation standards. With the breadth of material to cover during training, carefully o...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2020.12.022
更新日期:2021-01-21 00:00:00
abstract:RATIONALE AND OBJECTIVES:The authors evaluated the diagnostic accuracy of viewing computed tomographic (CT) scans as film versus soft-copy images at a workstation. METHODS:Receiver operating characteristic analysis of the interpretation of 202 CT scans (103 were normal, 99 were abnormal) by five neuroradiologists was ...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(97)80004-9
更新日期:1997-02-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The development of curriculum guidelines for radiology residency has been found to be favored by 80% of program directors (PDs) nationwide. I surveyed PDs to develop a consensus of opinion concerning minimum training requirements in the subspecialty rotations. METHODS:A survey developed by mem...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(96)80013-4
更新日期:1996-06-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The Mammography Quality Standards Act requires practices to measure limited aspects of their performance. The authors conducted this study to calculate the differences in measurements of sensitivity and specificity due only to differences in the definitions used in the analysis. This included d...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(00)80057-4
更新日期:2000-12-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Dual-energy computed tomography (DECT) and ultrasound are both used to assess gouty arthritis. The present study was designed to compare the diagnostic accuracy of DECT and ultrasound in detecting monosodium urate (MSU) crystal deposition in various joints. MATERIALS AND METHODS:This study enr...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2015.08.010
更新日期:2015-12-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The purpose of our study is to perform an internal validation of a new reference standard for vasospasm diagnosis in aneurysmal subarachnoid hemorrhage (A-SAH) patients. MATERIALS AND METHODS:A retrospective study was performed on A-SAH patients between January 2002 and May 2009. All patients ...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2010.04.025
更新日期:2010-09-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:This study aimed to measure apparent diffusion coefficient (ADC) in Chinese patients with newly diagnosed multiple myeloma by whole-body diffusion-weighted magnetic resonance imaging (WB-DWI MRI) and assess the diagnostic accuracy of ADC in the discrimination of deep response to induction chemo...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2017.12.008
更新日期:2018-07-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Acute and chronic graft rejection remains the major problem in clinical surveillance of lung-transplanted patients and early detection of complications is of capital importance to allow the optimal therapeutic option. The aim of this study was to investigate the role of quantitative non contras...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2020.05.026
更新日期:2020-07-08 00:00:00
abstract:RATIONALE AND OBJECTIVES:Estimation of regional lung function parameters from hyperpolarized gas magnetic resonance images can be very sensitive to presence of noise. Clustering pixels and averaging over the resulting groups is an effective method for reducing the effects of noise in these images, commonly performed by...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2008.03.002
更新日期:2008-06-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Scanning parameters used in multislice computed tomographic (MSCT) coronary angiography should be adapted to patients' heart rates. The aim of this study was to evaluate the rate of success of a software-assisted scan simulation to determine optimal gantry rotation time prior to MSCT coronary a...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2008.08.016
更新日期:2009-02-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The aim of the present study was to examine the usefulness and record the complications of preoperative lipiodol marking using computed tomographic (CT) fluoroscopy for the intraoperative localization of 107 pulmonary nodules. METHODS:Lipiodol marking was performed under CT fluoroscopic guidan...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2008.07.012
更新日期:2009-01-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Catheter-directed intraarterial (IA) injections of gadolinium contrast agents may be used during endovascular interventions with magnetic resonance (MR) imaging guidance. Injection protocols require further validation. Using a flow phantom and swine, the authors aimed to (a) measure the optimal...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(03)80167-8
更新日期:2002-02-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The Accreditation Council on Graduate Medical Education (ACGME) through its Outcome Project requires training programs in all medical specialties to integrate six general competencies into residency training: patient care, medical knowledge, professionalism, interpersonal and communication skil...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2010.12.016
更新日期:2011-05-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The increasing use of computed tomography (CT) has been accompanied by rising concerns over potential radiation-related health risks, especially cancer, and a need to minimize such risks. MATERIALS AND METHODS:We conducted 2186 low-dose helical chest CT scans among 1235 nuclear weapons workers...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2011.09.015
更新日期:2012-01-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:We investigated the methodologic development of computed microtomography (CMT) for monitoring the development of osteoporosis in male Sprague-Dawley rats. METHODS:Eight rats were gastrectomized and eight rats were sham operated. Femurs, tibias, and tails were prepared, and CMT scans with spati...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(05)80487-8
更新日期:1995-09-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To investigate the capability of delta-radiomics to predict pathological complete response (pCR) after neoadjuvant chemoradiotherapy (nCRT) in patients with locally advanced rectal cancer (LARC). MATERIALS AND METHODS:This retrospective study enrolled 165 consecutive patients with LARC (traini...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2020.10.026
更新日期:2020-11-11 00:00:00
abstract:RATIONALE AND OBJECTIVES:Physiological measurements from coronary angiography show that coronary stenosis with necrotic core plaque reduces coronary flow reserve (CFR). Myocardial flow reserve (MFR) estimated by 13N-ammonia PET (NH3-PET) is a different index from CFR. Low attenuation plaque (LAP) on coronary CTA (CCTA)...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2020.11.012
更新日期:2020-12-03 00:00:00
abstract:RATIONALE AND OBJECTIVES:This study presents a method for generating breast masses and microcalcifications in mammography via simulation. This simulation method allows for the creation of large image datasets with particular lesions, which may serve as a useful tool for perception studies measuring imaging system perfo...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2006.03.015
更新日期:2006-07-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:A survey was administered to fourth-year radiology residents after receiving their results from the first American Board of Radiology (ABR) Core examination in 2013. The purpose was to gather information regarding resources and study strategies to share with program directors and future residen...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2014.07.026
更新日期:2015-01-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:This study aimed to determine whether uterine leiomyoma can be distinguished from uterine leiomyosarcoma on ultrasound (US), computed tomography (CT), and/or magnetic resonance imaging (MRI) without diffusion-weighted imaging. MATERIALS AND METHODS:Institutional review board approval was obtai...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2016.06.004
更新日期:2016-10-01 00:00:00
abstract:RATIONALE AND OBJECTIVE:Among artifacts on three-dimensional (3D) angiograms, pseudostenosis in vessels adjacent to intracranial aneurysms has not been described. By using a phantom, artifacts seen in vessels adjacent to intracranial aneurysms on volume-rendered 3D angiograms were assessed. MATERIALS AND METHODS:Using...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2004.12.003
更新日期:2005-03-01 00:00:00
abstract:OBJECTIVE:This study was to investigate the CT quantification of COVID-19 pneumonia and its impacts on the assessment of disease severity and the prediction of clinical outcomes in the management of COVID-19 patients. MATERIALS METHODS:Ninety-nine COVID-19 patients who were confirmed by positive nucleic acid test (NAT...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2020.09.004
更新日期:2020-12-01 00:00:00
abstract::Medical eponyms are ubiquitous, numerous, and at times controversial. They are often useful for succinctly conveying complex concepts, and familiarity with eponyms is important for proper usage and appropriate communication. In this historical review, we identify 18 anatomic eponyms used to describe structures of the ...
journal_title:Academic radiology
pub_type: 传,历史文章,杂志文章,评审
doi:10.1016/j.acra.2016.01.008
更新日期:2016-06-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Total kidney volume is an important biomarker for the evaluation of autosomal dominant polycystic kidney disease progression. In this study, we present a novel approach for automated segmentation of polycystic kidneys from non-contrast-enhanced computed tomography (CT) images. MATERIALS AND ME...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2017.11.015
更新日期:2018-07-01 00:00:00
abstract:BACKGROUND:The use of cardiac computed tomography (cardiac CT) and the quantification of the Agatston score for the evaluation of calcium of the aortic valve (AVC) has increased in different clinical contexts for diagnostic and prognostic purposes. This study aims to evaluate the correlation between cardiac CT and hist...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2020.12.015
更新日期:2021-01-14 00:00:00
abstract:RATIONALE AND OBJECTIVES:Ki-67 is one of the most important biomarkers of breast cancer traditionally measured invasively via immunohistochemistry. In this study, deep learning based radiomics models were established for preoperative prediction of Ki-67 status using multiparametric magnetic resonance imaging (mp-MRI). ...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2020.02.006
更新日期:2021-02-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The purpose of this study was to evaluate the American College of Radiology (ACR) accreditation phantom for assessing image quality in digital mammography. MATERIALS AND METHODS:Digital images were obtained of an ACR accreditation phantom at varying mAs (constant kVp) and varying kVp (constant...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(03)80345-8
更新日期:2002-07-01 00:00:00