Hemodynamic implications of left bundle branch block.

Abstract:

:Left bundle branch block (LBBB), traditionally viewed as an electrophysiologic abnormality, is increasingly recognized for its profound hemodynamic effects. LBBB causes asynchronous myocardial activation, which, in turn, may trigger ventricular remodeling. Exercise nuclear studies frequently show reversible perfusion defects in the absence of obstructive coronary artery disease and some patients with intermittent LBBB develop angina coincident with the onset of LBBB. It is uncertain, however, if these phenomena are because of myocardial ischemia or ventricular asynergy. LBBB is associated with impaired systolic and diastolic function. In patients with dilated cardiomyopathy (DCM), LBBB is accompanied by progressive left ventricular (LV) dilatation and mitral regurgitation. It is not known whether LBBB is the cause or the consequence of LV dilatation. DCM patients with LBBB, as compared to those with normal intraventricular conduction, are more likely to have a nonischemic etiology, profound LV dilatation, lower ejection fraction, increased symptomatology, and shorter survival. Patients with DCM and acceleration-dependent LBBB may benefit from restoration of a narrow QRS complex by suppressing the heart rate with beta-blocker. There is extensive research underway in patients with DCM and LBBB to evaluate the short and long-term effects of normalization of ventricular activation sequence with high septal, LV, or biventricular pacing.

journal_name

J Electrocardiol

authors

Littmann L,Symanski JD

doi

10.1054/jelc.2000.20330

keywords:

subject

Has Abstract

pub_date

2000-01-01 00:00:00

pages

115-21

eissn

0022-0736

issn

1532-8430

journal_volume

33 Suppl

pub_type

杂志文章,评审
  • Ablation of nonparoxysmal A-V nodal tachycardia.

    abstract::The present study describes the successful radiofrequency ablation of an uncommon type of A-V nodal tachycardia. Electroanatomical mapping of the right atria was used to locate the region of the earliest atrial activation and allowed for positioning of the ablation catheter and a successful 25-watt radiofrequency burn...

    journal_title:Journal of electrocardiology

    pub_type: 杂志文章

    doi:10.1054/jelc.2002.29943

    authors: Pollak SJ,Dreifus LS

    更新日期:2002-01-01 00:00:00

  • Studies of acute myocardial infarction with intermittent bundle branch and hemiblock.

    abstract::Two cases of transient hemiblock occurring during the course of acute myocardial infarction are reported. The transient manifestation permits the accurate evaluation of the diagnostic features of the hemiblocks as modified by acute infarction. One case reflects the development of left bundle branch block due to bilate...

    journal_title:Journal of electrocardiology

    pub_type: 杂志文章

    doi:10.1016/s0022-0736(78)80109-5

    authors: Schamroth L,Friedberg HD,de Kock J

    更新日期:1978-04-01 00:00:00

  • Spectrotemporal and spectral turbulence analysis of the signal-averaged P wave in paroxysmal atrial fibrillation.

    abstract::Patients with paroxysmal atrial fibrillation (AF) have greater overall P wave magnitude than control subjects, but the temporal localization of the increased energy is unknown. P wave spectral turbulence has not been investigated in such patients, and the optimum methodology for studying P wave signals has not been de...

    journal_title:Journal of electrocardiology

    pub_type: 杂志文章

    doi:10.1016/s0022-0736(97)80013-1

    authors: Stafford PJ,Vincent R

    更新日期:1997-04-01 00:00:00

  • Effect of pacing drive cycle length on induction of sustained monomorphic ventricular tachycardia.

    abstract::To assess the effect of pacing drive cycle length on induction of sustained monomorphic ventricular tachycardia, 40 patients were prospectively studied in the drug-free state. Ventricular extrastimuli were sequentially delivered at the same coupling interval at each of three drive cycle lengths (600, 500, and 400 ms) ...

    journal_title:Journal of electrocardiology

    pub_type: 杂志文章

    doi:10.1016/0022-0736(92)90127-l

    authors: Mann DE,Florek RC,Reiter MJ

    更新日期:1992-01-01 00:00:00

  • Three-dimensional endocardial mapping system using a novel x-ray imager and locating catheter.

    abstract::Percutaneous radiofrequency catheter ablation (RFCA) has a very high success rate for certain arrhythmias, such as Wolff-Parkinson-White syndrome and idiopathic ventricular tachycardias in the right ventricular outflow tract. These arrhythmias are typically characterized by a single site of arrhythmogenic tissue that ...

    journal_title:Journal of electrocardiology

    pub_type: 杂志文章

    doi:10.1016/s0022-0736(94)80073-1

    authors: Moorman JW,Melen RE,Skillicorn B,Solomon EG

    更新日期:1994-01-01 00:00:00

  • Pacemaker repetitive nonreentrant ventriculoatrial synchrony. Why did automatic mode switching occur?

    abstract::Repetitive nonreentrant ventriculoatrial synchrony during dual-chamber pacing is characterized by long intervals alternating with short intervals. This arrangement activated automatic mode switching in a St Jude dual-chamber pacemaker in which the algorithm requires an atrial sensed event for automatic mode switching ...

    journal_title:Journal of electrocardiology

    pub_type: 杂志文章

    doi:10.1016/j.jelectrocard.2012.04.003

    authors: Barold SS,Stroobandt RX,Van Heuverswyn F

    更新日期:2012-07-01 00:00:00

  • Signal processing options for detecting conduction abnormalities in ischemic ventricles.

    abstract::Sources of error in averaging for late ventricular potentials include variations in the magnitude and timing of late potentials as well as variability in the temporal alignment of successive cardiac cycles during averaging. Since these errors can both attenuate high frequency signals and add artifactual components to ...

    journal_title:Journal of electrocardiology

    pub_type: 杂志文章

    doi:

    authors: Craelius W,Restivo M,el-Sherif N

    更新日期:1987-10-01 00:00:00

  • Evaluation of ECG algorithms designed to improve detect of transient myocardial ischemia to minimize false alarms in patients with suspected acute coronary syndrome.

    abstract:BACKGROUND:Patients hospitalized for suspected acute coronary syndrome (ACS) are at risk for transient myocardial ischemia. During the "rule-out" phase, continuous ECG ST-segment monitoring can identify transient myocardial ischemia, even when asymptomatic. However, current ST-segment monitoring software is vastly unde...

    journal_title:Journal of electrocardiology

    pub_type: 杂志文章

    doi:10.1016/j.jelectrocard.2017.10.005

    authors: Pelter MM,Xu Y,Fidler R,Xiao R,Mortara DW,Xiao H

    更新日期:2018-01-01 00:00:00

  • Effect of nitroglycerin on ST potentials in the post-acute phase of myocardial infarction.

    abstract::Thoracic electromaps were recorded before and after sublingual nitroglycerin (NG) in 26 subjects 15 and 30 days after acute myocardial infarction (MI), in order to evaluate the effect of the drug on injury potentials. Ten patients with documented left ventricular aneurysm were also studied 5 to 46 months after acute M...

    journal_title:Journal of electrocardiology

    pub_type: 杂志文章

    doi:10.1016/s0022-0736(81)81007-2

    authors: De Ambroggi L,Landolina M,Todeschini P,Galdangelo F,Ravizza P

    更新日期:1981-10-01 00:00:00

  • Rate dependent variation in concealed bigeminy.

    abstract::A 63 year old man with angina pectoris was found to have frequent extrasystoles separated by odd as well as even numbers of conducted sinus beats. Analysis of 935 conducted sinus beats showed that premature ventricular beats without interpolation were separated by odd numbers of conducted sinus beats in 117 sequences ...

    journal_title:Journal of electrocardiology

    pub_type: 杂志文章

    doi:10.1016/s0022-0736(82)80033-2

    authors: Bissett JK,Watson JW,Wanta-Matthews M,Ozemek H

    更新日期:1982-01-01 00:00:00

  • Time domain parameters can be estimated with less statistical error than frequency domain parameters in the analysis of heart rate variability.

    abstract:INTRODUCTION:Measures of heart rate variability (HRV) can be divided in time domain and frequency domain parameters. It is frequently ignored that estimation of frequency-domain parameters is a 2-step procedure where statistical error from the first step (spectral estimation) is neglected in subsequent analyses. METHO...

    journal_title:Journal of electrocardiology

    pub_type: 杂志文章

    doi:10.1016/j.jelectrocard.2008.02.014

    authors: Kuss O,Schumann B,Kluttig A,Greiser KH,Haerting J

    更新日期:2008-07-01 00:00:00

  • A transparent overlay for assessing amplitude of ECG wave forms.

    abstract::The amplitude of ECG wave forms can be evaluated rapidly and accurately with the help of a transparent overlay depicting images of the P-QRS-T complex in various leads. Such images are drawn between the upper and lower limits of normal amplitude values and by placing them over the corresponding P-QRS-T complexes in th...

    journal_title:Journal of electrocardiology

    pub_type: 杂志文章

    doi:10.1016/s0022-0736(81)80033-7

    authors: Wartak J

    更新日期:1981-01-01 00:00:00

  • A completely automated activation-repolarization interval algorithm for directly coupled unipolar electrograms and its three-dimensional correlation with refractory periods.

    abstract::Sintered Ag-AgCl needle electrodes were used to record unipolar directly coupled (DC) electrograms transmurally from right and left ventricular myocardium. Direct coupling yields unfiltered low-frequency signal content, preserving repolarization waveform morphology. These electrograms were analyzed using completely au...

    journal_title:Journal of electrocardiology

    pub_type: 杂志文章

    doi:10.1016/0022-0736(88)90102-1

    authors: Witkowski FX,Penkoske PA

    更新日期:1988-08-01 00:00:00

  • Extra AV nodal Wenckebach periodicity.

    abstract::Extra AV nodal Wenckebach periodicity was diagnosed in seven patients. The most frequent form of this conduction abnormality was an exit block. The underlying block was localized in the sinoatrial junction and in the atria in two patients; the AV junction and the ventricle were the site of the Wenckebach periodicity i...

    journal_title:Journal of electrocardiology

    pub_type: 杂志文章

    doi:10.1016/s0022-0736(81)80003-9

    authors: Schweitzer P,Choudhry M,Kunkes SH,Ress R,Mark H

    更新日期:1981-07-01 00:00:00

  • Electrocardiographic and vectorcardiographic study of interatrial conduction disturbances with left atrial retrograde activation.

    abstract::From 81,000 ECGs we collected 83 cases that fulfilled the criteria of Interatrial Conduction Disturbances with Left Atrial Retrograde Activation (IACD-LARA) (P +/- in II, III and VF with P width greater than or equal to 120 msec.). We present the detailed study of 35 cases with surface ECG and VCG and 29 cases with or...

    journal_title:Journal of electrocardiology

    pub_type: 杂志文章

    doi:10.1016/s0022-0736(85)80029-7

    authors: Bayes de Luna A,Fort de Ribot R,Trilla E,Julia J,Garcia J,Sadurni J,Riba J,Sagues F

    更新日期:1985-01-01 00:00:00

  • Electrocardiogram voltage discordance: Interpretation of low QRS voltage only in the precordial leads.

    abstract:OBJECTIVES:To define clinical correlates of low voltage isolated to precordial leads on the surface electrocardiogram (ECG). INTRODUCTION:Low voltage (V) on the ECG is defined as QRS V<5mm in all limb leads and <10mm in all precordial leads. The diagnostic use of ECGs with low voltage isolated to the precordial leads ...

    journal_title:Journal of electrocardiology

    pub_type: 杂志文章

    doi:10.1016/j.jelectrocard.2017.04.016

    authors: Kim DH,Verdino RJ

    更新日期:2017-01-01 00:00:00

  • Autonomic ST-segment elevation: A carotid stent and early repolarization.

    abstract::Benign Early Repolarization is seen most commonly in young males and is thought to arise from left ventricular hypertrophy, vagal tone and hereditary predilection. This case describes an elderly man with Early Repolarization mimicking acute myocardial infarction after a carotid stent procedure. ...

    journal_title:Journal of electrocardiology

    pub_type: 杂志文章

    doi:10.1016/j.jelectrocard.2020.05.002

    authors: Wilson JM

    更新日期:2020-01-01 00:00:00

  • Direct Wenckebach periods in the left bundle branch during bradycardia-dependent left bundle branch block in a patient with sick sinus syndrome.

    abstract::Direct Wenckebach periods in the left bundle branch with periods of 4:3 and 5:4 conduction alternating with 2:1 left bundle branch block (LBBB) were observed in a patient who was admitted because of congestive heart failure. There was no previous documented LBBB and serial electrocardiographic (ECG) mainfestations aft...

    journal_title:Journal of electrocardiology

    pub_type: 杂志文章

    doi:10.1016/s0022-0736(80)80034-3

    authors: Izumi K

    更新日期:1980-01-01 00:00:00

  • QRS broadening due to terminal distortion is associated with the size of myocardial injury in experimental myocardial infarction.

    abstract:INTRODUCTION:Not only repolarization, but also depolarization ECG indexes reflect the progression of ischemic injury. The aim was to assess the QRS duration and morphology dynamics during the prolonged coronary occlusion and their association with the myocardial area at risk (MaR) and final infarct size (IS). METHODS:...

    journal_title:Journal of electrocardiology

    pub_type: 杂志文章

    doi:10.1016/j.jelectrocard.2016.03.014

    authors: Demidova MM,Martín-Yebra A,Koul S,Engblom H,Martínez JP,Erlinge D,Platonov PG

    更新日期:2016-05-01 00:00:00

  • Ten years of genes in inherited arrhythmia syndromes: an example of what we have learned from patients, electrocardiograms, and computers.

    abstract::In the last 10 years the molecular substrate of a diversity of primary electrical diseases has been unraveled. Disease-causing mutations in ion-channel genes have been identified and have challenged clinical and basic electrophysiologists to mechanistically link the observed genetic aberrancies to the phenotype. Indee...

    journal_title:Journal of electrocardiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jelectrocard.2005.06.103

    authors: Wilde AA,van den Berg MP

    更新日期:2005-10-01 00:00:00

  • CSE (common standards for quantitative electrocardiography) data testing in Japan.

    abstract::The authors comment on the present status of computerized electro-cardiogram (ECG) works in Japan and demonstrate the preliminary tentative results of CSE (common standards for quantitative electrocardiography) data analysis using the Nagoya program. The more detailed results of the performance of several programs in ...

    journal_title:Journal of electrocardiology

    pub_type: 杂志文章

    doi:10.1016/0022-0736(88)90087-8

    authors: Okamoto N,Ohsawa N

    更新日期:1988-01-01 00:00:00

  • Standards for the function of an academic 12-lead electrocardiographic core laboratory.

    abstract::An academic 12-lead electrocardiogram (ECG) core laboratory aims to provide the highest possible quality ECG recording, measurement, and storage to aid clinicians in research into important cardiovascular outcomes and to maximize the credibility of scientific results based solely, or in part, on ECG data. This positio...

    journal_title:Journal of electrocardiology

    pub_type: 杂志文章

    doi:10.1054/jelc.2001.22028

    authors: Anderson ST,Pahlm O,Bacharova L,Barbagelata A,Chaitman BR,Clemmensen P,Goodman S,Hedén B,Klootwijk PJ,Lauer M,MacFarlane PW,Rautaharju P,Reddy S,Selvester RH,Sgarbossa EB,Underwood D,Warner RA,Wagner GS

    更新日期:2001-01-01 00:00:00

  • Overcoming barriers to developing seamless ST-segment elevation myocardial infarction care systems in the United States: recommendations from a comprehensive Prehospital 12-lead Electrocardiogram Working Group.

    abstract:BACKGROUND:Reducing time to reperfusion treatment for patients with ST-segment elevation myocardial infarction (STEMI) improves patient outcomes. Few medical systems consistently meet current benchmarks regarding timely access to treatment. Studies have widely demonstrated that prehospital 12-lead electrocardiography c...

    journal_title:Journal of electrocardiology

    pub_type: 杂志文章

    doi:10.1016/j.jelectrocard.2009.03.011

    authors: Frendl DM,Palmeri ST,Clapp JR Jr,Hampton D,Sejersten M,Young D,Drew B,Farrell R,Innes J,Russell J,Rowlandson GI,Purim-Shem-Tov Y,Underhill BK,Zhou S,Wagner GS,Journal of Electrocardiology Prehospital 12-lead ECG Working Gro

    更新日期:2009-09-01 00:00:00

  • The reliability of pacemaker electrode-leads.

    abstract::Extensive experience has been obtained with Medtronic pacemakers, in Glasgow where over 400 patients have received their primary implant. In this review, which covers a period of seven and a half years ending December 31, 1973, the technical reliability of electrode-leads is considered in terms of failed implant lifet...

    journal_title:Journal of electrocardiology

    pub_type: 杂志文章

    doi:10.1016/s0022-0736(75)80030-6

    authors: Green GD

    更新日期:1975-01-01 00:00:00

  • Population-based study of heart rate variability and prevalent myocardial infarction. The Atherosclerosis Risk in Communities Study.

    abstract::Clinically based studies have indicated that patients who have suffered myocardial infarction (MI) exhibit lower heart rate variability (HRV). Such associations have not been reported at the population level. To investigate whether MI is related to lower HRV in the general population, the authors examined a stratified...

    journal_title:Journal of electrocardiology

    pub_type: 杂志文章

    doi:10.1016/s0022-0736(96)80082-3

    authors: Liao D,Evans GW,Chambless LE,Barnes RW,Sorlie P,Simpson RJ Jr,Heiss G

    更新日期:1996-07-01 00:00:00

  • Electrocardiographic features of ventricular pacing lead in the middle cardiac vein vs. right ventricular apex in a patient with persistent left superior vena cava.

    abstract::A 53-year-old woman with sinus node dysfunction underwent dual-chamber pacemaker implantation through a persistent left superior vena cava draining into the coronary sinus, which was detected at the time of implantation. We managed to fix the ventricular lead in the right ventricular (RV) apex by forming a clockwise l...

    journal_title:Journal of electrocardiology

    pub_type: 杂志文章

    doi:10.1016/j.jelectrocard.2007.05.016

    authors: Chen TE,Wang CC,Satish OS,Wu D

    更新日期:2007-11-01 00:00:00

  • Prevalence and predictors of severe autonomic failure in patients with insulin-dependent type 2 diabetes mellitus and coronary artery disease: pilot study.

    abstract:BACKGROUND:Presence of severe autonomic failure (SAF), defined as coincidence of abnormal heart rate turbulence and abnormal deceleration capacity, identifies a group of patients with very poor prognosis among post-infarction patients with diabetes mellitus. However, factors contributing to development of SAF are entir...

    journal_title:Journal of electrocardiology

    pub_type: 杂志文章

    doi:10.1016/j.jelectrocard.2012.07.010

    authors: Zuern CS,Rizas K,Eick C,Sterz K,Gawaz M,Bauer A

    更新日期:2012-11-01 00:00:00

  • Electrocardiographic prediction of lateral involvement in acute non-anterior wall myocardial infarction.

    abstract:PURPOSE:Recent research has established that a tall R-wave in V1 indicates lateral wall involvement in non-anterior wall myocardial infarction (MI). The objective of this study was to assess the value of the admission electrocardiogram (ECG) to predict R-waves and consequently lateral wall damage in the late phase of n...

    journal_title:Journal of electrocardiology

    pub_type: 杂志文章

    doi:10.1016/j.jelectrocard.2015.02.005

    authors: Norda S,van der Weg K,Vos R,Gorgels AP

    更新日期:2015-07-01 00:00:00

  • Segmental atrial fibrillation resulting in chronic atrial dissociation. A case report.

    abstract::Atrial arrhythmias are diagnosed on the basis of the analysis of P wave morphology, timing and rate, the surface electrocardiogram, and intracardiac recordings. Recent intracardiac studies have demonstrated dissimilar atrial rhythms with direct intra-atrial recordings, the former otherwise not evident on the surface E...

    journal_title:Journal of electrocardiology

    pub_type: 杂志文章

    doi:10.1016/0022-0736(91)90010-j

    authors: Martinez EE,Pontes S,dePaola AA,Gomes JA

    更新日期:1991-04-01 00:00:00

  • Remodeling of cardiac gap junctions: the relationship to the genesis of ventricular tachycardia.

    abstract::Cardiac gap junctions are responsible for normal conduction properties of the ventricles. Alteration in gap junction distribution (remodeling) in ischemic heart disease is likely to be an important cause of life threatening ventricular arrhythmias. ...

    journal_title:Journal of electrocardiology

    pub_type: 杂志文章

    doi:10.1054/jelc.2001.28834

    authors: Wit AL

    更新日期:2001-01-01 00:00:00