Spiritual healing as a therapy for chronic pain: a randomized, clinical trial.

Abstract:

:Spiritual healing is a popular complementary and alternative therapy; in the UK almost 13000 members are registered in nine separate healing organisations. The present randomized clinical trial was designed to investigate the efficacy of healing in the treatment of chronic pain. One hundred and twenty patients suffering from chronic pain, predominantly of neuropathic and nociceptive origin resistant to conventional treatments, were recruited from a Pain Management Clinic. The trial had two parts: face-to-face healing or simulated face-to-face healing for 30 min per week for 8 weeks (part I); and distant healing or no healing for 30 min per week for 8 weeks (part II). The McGill Pain Questionnaire was pre-defined as the primary outcome measure, and sample size was calculated to detect a difference of 8 units on the total pain rating index of this instrument after 8 weeks of healing. VASs for pain, SF36, HAD scale, MYMOP and patient subjective experiences at week 8 were employed as secondary outcome measures. Data from all patients who reached the pre-defined mid-point of 4 weeks (50 subjects in part I and 55 subjects in part II) were included in the analysis. Two baseline measurements of outcome measures were made, 3 weeks apart, and no significant differences were observed between them. After eight sessions there were significant decreases from baseline in McGill Pain Questionnaire total pain rating index score for both groups in part I and for the control group in part II. However, there were no statistically significant differences between healing and control groups in either part. In part I the primary outcome measure decreased from 32.8 (95% CI 28.5-37.0) to 23.3 (16.8-29.7) in the healing group and from 33.1 (27.2-38.9) to 26.1 (19.3-32.9) in the simulated healing group. In part II it changed from 29.6 (24.8-34.4) to 24.0 (18.7-29.4) in the distant healing group and from 31.0 (25.8-36.2) to 21.0 (15.7-26.2) in the no healing group. Subjects in healing groups in both parts I and II reported significantly more 'unusual experiences' during the sessions, but the clinical relevance of this is unclear. It was concluded that a specific effect of face-to-face or distant healing on chronic pain could not be demonstrated over eight treatment sessions in these patients.

journal_name

Pain

journal_title

Pain

authors

Abbot NC,Harkness EF,Stevinson C,Marshall FP,Conn DA,Ernst E

doi

10.1016/s0304-3959(00)00421-8

keywords:

subject

Has Abstract

pub_date

2001-03-01 00:00:00

pages

79-89

issue

1-2

eissn

0304-3959

issn

1872-6623

pii

S0304-3959(00)00421-8

journal_volume

91

pub_type

临床试验,杂志文章,随机对照试验

相关文献

PAIN文献大全
  • Difficult management of pain following sacrococcygeal chordoma: 13 months of subarachnoid infusion.

    abstract::We report on a patient suffering severe pain following a long-standing sacral chordoma in whom management of therapy and pain was extremely difficult. Because orally administered morphine was observed to be ineffective in the early stages of treatment, we tried to achieve pain relief by using epidural morphine. This w...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/0304-3959(94)90085-X

    authors: Aguilar JL,Espachs P,Roca G,Samper D,Cubells C,Vidal F

    更新日期:1994-11-01 00:00:00

  • Pain intensity rating training: results from an exploratory study of the ACTTION PROTECCT system.

    abstract::Clinical trial participants often require additional instruction to prevent idiosyncratic interpretations regarding completion of patient-reported outcomes. The Analgesic, Anesthetic, and Addiction Clinical Trial Translations, Innovations, Opportunities, and Networks (ACTTION) public-private partnership developed a tr...

    journal_title:Pain

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/j.pain.0000000000000502

    authors: Smith SM,Amtmann D,Askew RL,Gewandter JS,Hunsinger M,Jensen MP,McDermott MP,Patel KV,Williams M,Bacci ED,Burke LB,Chambers CT,Cooper SA,Cowan P,Desjardins P,Etropolski M,Farrar JT,Gilron I,Huang IZ,Katz M,Kerns RD

    更新日期:2016-05-01 00:00:00

  • Functional imaging in microfluidic chambers reveals sensory neuron sensitivity is differentially regulated between neuronal regions.

    abstract::Primary afferent sensory neurons are incredibly long cells, often traversing distances of over 1 m in humans. Cutaneous sensory stimuli are transduced in the periphery by specialised end organs or free nerve endings, which code the stimulus into electrical action potentials that propagate towards the central nervous s...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1097/j.pain.0000000000001145

    authors: Clark AJ,Menendez G,AlQatari M,Patel N,Arstad E,Schiavo G,Koltzenburg M

    更新日期:2018-07-01 00:00:00

  • Neuropharmacological basis of rTMS-induced analgesia: the role of endogenous opioids.

    abstract::We investigated the role of endogenous opioid systems in the analgesic effects induced by repetitive transcranial magnetic stimulation (rTMS). We compared the analgesic effects of motor cortex (M1) or dorsolateral prefrontal cortex (DLPFC) stimulation before and after naloxone or placebo treatment, in a randomized, do...

    journal_title:Pain

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.pain.2010.10.032

    authors: de Andrade DC,Mhalla A,Adam F,Texeira MJ,Bouhassira D

    更新日期:2011-02-01 00:00:00

  • Tooth extraction-induced internalization of the substance P receptor in trigeminal nucleus and spinal cord neurons: imaging the neurochemistry of dental pain.

    abstract::Although pains arising from the craniofacial complex can be severe and debilitating, relatively little is known about the peripheral and central mechanisms that generate and maintain orofacial pain. To better understand the neurons in the trigeminal complex and spinal cord that are activated following nociceptive stim...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/s0304-3959(01)00397-9

    authors: Sabino MA,Honore P,Rogers SD,Mach DB,Luger NM,Mantyh PW

    更新日期:2002-01-01 00:00:00

  • Brain measures of nociception using near-infrared spectroscopy in patients undergoing routine screening colonoscopy.

    abstract::Colonoscopy is an invaluable tool for the screening and diagnosis of many colonic diseases. For most colonoscopies, moderate sedation is used during the procedure. However, insufflation of the colon produces a nociceptive stimulus that is usually accompanied by facial grimacing/groaning while under sedation. The objec...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1097/j.pain.0000000000000446

    authors: Becerra L,Aasted CM,Boas DA,George E,Yücel MA,Kussman BD,Kelsey P,Borsook D

    更新日期:2016-04-01 00:00:00

  • Chronic effects of topical application of capsaicin to the sciatic nerve on responses of primate spinothalamic neurons.

    abstract::The responses of 144 spinothalamic tract (STT) cells were recorded in 15 anesthetized macaque monkeys (Macaca fascicularis). Three to 4 weeks prior to the acute experiment, the sciatic nerve was surgically exposed on one or both sides so that capsaicin or vehicle could be applied. Responses of STT cells recorded in 3 ...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/0304-3959(93)90227-G

    authors: Chung JM,Paik KS,Kim JS,Nam SC,Kim KJ,Oh UT,Hasegawa T,Chung K,Willis WD

    更新日期:1993-06-01 00:00:00

  • EVENDOL, a new behavioral pain scale for children ages 0 to 7 years in the emergency department: design and validation.

    abstract::Numerous behavioral pain measures have been validated for young children, but none is appropriate to assess pain in emergency departments (EDs), where caregivers need a simple, easily completed scale. Our objective was to elaborate and validate a tool, relevant in any painful situation, with agitation or prostration, ...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/j.pain.2012.02.024

    authors: Fournier-Charrière E,Tourniaire B,Carbajal R,Cimerman P,Lassauge F,Ricard C,Reiter F,Turquin P,Lombart B,Letierce A,Falissard B

    更新日期:2012-08-01 00:00:00

  • Cell size analysis of primary neurons innervating the cornea and tooth pulp of the rat.

    abstract::Primary neuronal cell bodies, whose peripheral axons comprised the cutaneous branch of the mylohyoid nerve or innervated the mandibular molar tooth pulp or the cornea, were labeled with HRP and their cross-sectional area was analyzed. Most of their cell bodies were smaller than 1000 microns2 in cross-sectional area an...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/0304-3959(88)90050-4

    authors: Sugimoto T,Takemura M,Wakisaka S

    更新日期:1988-03-01 00:00:00

  • Intraplantar injection of nerve growth factor into the rat hind paw: local edema and effects on thermal nociceptive threshold.

    abstract::Nerve growth factor (NGF) is known to produce hyperalgesia as well as to stimulate synthesis of neuropeptides in dorsal root ganglia (DRG). In the present study, we wanted to determine the effects of local NGF administration and assess to which extent mast cell-dependent factors are mediating NGF responses. Rats recei...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/0304-3959(95)00120-4

    authors: Amann R,Schuligoi R,Herzeg G,Donnerer J

    更新日期:1996-02-01 00:00:00

  • Phantom urinary bladder pain--case report.

    abstract::Phantom urinary phenomena are a relatively rare disease entity. Literature search has revealed only one case following cystectomy, seven cases following spinal cord injury and several other cases in hemodialysis patients. This report presents a case of painful phantom bladder following cystectomy for chronic kidney an...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/0304-3959(79)90011-3

    authors: Brena SF,Sammons EE

    更新日期:1979-10-01 00:00:00

  • Problems of long-term spinal opioid treatment in advanced cancer patients.

    abstract::Epidural and intrathecal techniques are well established techniques in cancer pain. However, several questions remain unresolved. The several problems of long-term spinal opioid treatment in advance cancer patients were reviewed. Indications for the use of spinal opioids include patients treated by systemic opioids wi...

    journal_title:Pain

    pub_type: 杂志文章,评审

    doi:10.1016/S0304-3959(98)00118-3

    authors: Mercadante S

    更新日期:1999-01-01 00:00:00

  • Pain catastrophizing is related to temporal summation of pain but not temporal summation of the nociceptive flexion reflex.

    abstract::Pain catastrophizing is associated with enhanced temporal summation of pain (TS-Pain). However, because prior studies have found that pain catastrophizing is not associated with a measure of spinal nociception (nociceptive flexion reflex [NFR] threshold), this association may not result from changes in spinal nocicept...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/j.pain.2010.12.041

    authors: Rhudy JL,Martin SL,Terry EL,France CR,Bartley EJ,DelVentura JL,Kerr KL

    更新日期:2011-04-01 00:00:00

  • Relationship between pain symptoms and referred sensory and trophic changes in patients with gallbladder pathology.

    abstract::The relationship was investigated between algogenic potential of gallbladder pathology and occurrence/extent of sensory and trophic changes in the referred area. Five groups of subjects were studied, with: symptomatic gallbladder calculosis (3-20 colics); asymptomatic calculosis; symptomatic gallbladder shape abnormal...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/j.pain.2004.12.024

    authors: Giamberardino MA,Affaitati G,Lerza R,Lapenna D,Costantini R,Vecchiet L

    更新日期:2005-03-01 00:00:00

  • Enhancing analgesic spinal cord stimulation for chronic pain with personalized immersive virtual reality.

    abstract:ABSTRACT:Spinal cord stimulation (SCS) is an approved treatment for truncal and limb neuropathic pain. However, pain relief is often suboptimal and SCS efficacy may reduce over time, requiring sometimes the addition of other pain therapies, stimulator revision, or even explantation. We designed and tested a new procedu...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1097/j.pain.0000000000002160

    authors: Solcà M,Krishna V,Young N,Deogaonkar M,Herbelin B,Orepic P,Mange R,Rognini G,Serino A,Rezai A,Blanke O

    更新日期:2020-11-30 00:00:00

  • Morphine and ibuprofen compared using the cold pressor test.

    abstract::The analgesic efficacy of single doses of oral morphine sulphate solution (10 mg) and ibuprofen 600 mg was compared in 12 volunteers using a double-blind, double-dummy, placebo-controlled design on the cold pressor experimental pain model. Measurement of pain intensity was made before medication and then at 30, 60, 90...

    journal_title:Pain

    pub_type: 临床试验,杂志文章

    doi:10.1016/0304-3959(88)90156-X

    authors: Jones SF,McQuay HJ,Moore RA,Hand CW

    更新日期:1988-08-01 00:00:00

  • Dual influence of the striatum on neuropathic hypersensitivity.

    abstract::We studied whether striatal alpha(2)-adrenoceptors or N-methyl-d-aspartate (NMDA) receptors influence descending regulation of neuropathic hypersensitivity in the rat by microinjecting an alpha(2)-adrenoceptor agonist or NMDA-receptor antagonist into the dorsal striatum in animals with a spinal nerve ligation-induced ...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/j.pain.2007.08.009

    authors: Pertovaara A,Wei H

    更新日期:2008-07-01 00:00:00

  • Adverse event reporting in randomised controlled trials of neuropathic pain: considerations for future practice.

    abstract::High-quality information on the potential benefit and harm of a drug is required for patients and clinicians to make informed treatment decisions and to enable cost-effectiveness modeling to be undertaken. This systematic review describes the collection and reporting of adverse event data as presented in published cli...

    journal_title:Pain

    pub_type: 杂志文章,评审

    doi:10.1016/j.pain.2012.08.012

    authors: Cornelius VR,Sauzet O,Williams JE,Ayis S,Farquhar-Smith P,Ross JR,Branford RA,Peacock JL

    更新日期:2013-02-01 00:00:00

  • Peripherally restricted cannabinoid 1 receptor agonist as a novel analgesic in cancer-induced bone pain.

    abstract::Many malignant cancers, including breast cancer, have a propensity to invade bones, leading to excruciating bone pain. Opioids are the primary analgesics used to alleviate this cancer-induced bone pain (CIBP) but are associated with numerous severe side effects, including enhanced bone degradation, which significantly...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1097/j.pain.0000000000001278

    authors: Zhang H,Lund DM,Ciccone HA,Staatz WD,Ibrahim MM,Largent-Milnes TM,Seltzman HH,Spigelman I,Vanderah TW

    更新日期:2018-09-01 00:00:00

  • Quality indicators to assess quality of pain clinic care from the perspective of patients with chronic pain: development, usability, comprehensibility, and psychometric quality of the QiPPP questionnaire.

    abstract::To address the lack of appropriate patient-defined quality indicators (QIs) for assessment of pain clinic care in the Netherlands, we developed the "Quality Indicators Pain Patients' Perspective" (QiPPP) questionnaire. Quality indicators are widely used to measure the quality of the structure, process, and outcome of ...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1097/j.pain.0000000000001371

    authors: de Meij N,Köke A,Thomassen I,Kallewaard JW,van Kleef M,van der Weijden T

    更新日期:2018-12-01 00:00:00

  • Induction of long-term potentiation of C fibre-evoked spinal field potentials requires recruitment of group I, but not group II/III metabotropic glutamate receptors.

    abstract::In superficial layers of the lumbar spinal dorsal horn, N-methyl-D-aspartate-dependent long-term potentiation (LTP) of C fibre-evoked field potentials, a synaptic model of central sensitisation and hyperalgesia, ensues the application of electrical high-frequency, high-intensity conditioning stimulation to the sciatic...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/j.pain.2003.08.007

    authors: Azkue JJ,Liu XG,Zimmermann M,Sandkühler J

    更新日期:2003-12-01 00:00:00

  • Anger and pain sensitivity in chronic low back pain patients and pain-free controls: the role of endogenous opioids.

    abstract::The experience of anger (i.e. trait anger) and anger management style (i.e. anger-in, anger-out) are related to sensitivity to acute and chronic pain stimuli, although underlying mechanisms are unknown. This study tested whether anger variables are associated with impaired endogenous opioid antinociceptive activity, a...

    journal_title:Pain

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0304-3959(02)00104-5

    authors: Bruehl S,Burns JW,Chung OY,Ward P,Johnson B

    更新日期:2002-09-01 00:00:00

  • Short-term infusion of the mu-opioid agonist remifentanil in humans causes hyperalgesia during withdrawal.

    abstract::Numerous animal studies suggest that acute and chronic exposure to opioids can be associated with the development of hyperalgesia, i.e. an increased sensitivity to noxious stimuli. Hyperalgesia has been documented during withdrawal and on occasion while animals were still exposed to opioids. A pivotal role in the gene...

    journal_title:Pain

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0304-3959(03)00276-8

    authors: Angst MS,Koppert W,Pahl I,Clark DJ,Schmelz M

    更新日期:2003-11-01 00:00:00

  • Treatment outcome and compliance with therapeutic regimens: long-term follow-up of a multidisciplinary pain program.

    abstract::Fifty-seven patients (74%) who had completed a multidisciplinary pain program returned mailed questionnaires assessing both outcome and compliance measures. Significant treatment gains were observed at follow-up. Compliance with prescribed therapeutic regimens was low, averaging around 42% for individual regimens. Com...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/0304-3959(83)90102-1

    authors: Lutz RW,Silbret M,Olshan N

    更新日期:1983-11-01 00:00:00

  • The bee venom test: a new tonic-pain test.

    abstract::The present study describes a new test of tonic pain to be used as an animal model of persistent pain. First, pain responses and edema produced by subcutaneous injection of increasing doses of honey bee venom into the hind paw of the rat were quantified. Second, the effect of morphine and aspirin on the pain responses...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/0304-3959(96)03075-8

    authors: Lariviere WR,Melzack R

    更新日期:1996-08-01 00:00:00

  • Descending analgesia--when the spine echoes what the brain expects.

    abstract::Changes in pain produced by psychological factors (e.g., placebo analgesia) are thought to result from the activity of specific cortical regions. However, subcortical nuclei, including the periaqueductal gray and the rostroventral medulla, also show selective activation when subjects expect pain relief. These brainste...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/j.pain.2006.11.011

    authors: Goffaux P,Redmond WJ,Rainville P,Marchand S

    更新日期:2007-07-01 00:00:00

  • Differential utility of medical procedures in the assessment of chronic pain patients.

    abstract::Physicians are frequently called upon to evaluate patients with chronic pain to (1) establish the etiology, (2) determine the extent of impairment and disability, and (3) prescribe treatment. In many cases, there is little agreement as to what evaluation procedures should be used or how to weight and integrate these f...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/0304-3959(88)90181-9

    authors: Rudy TE,Turk DC,Brena SF

    更新日期:1988-07-01 00:00:00

  • The experience of pain from the shoulder-neck area related to the total body pain, self-experienced health and mental distress. The Malmö Shoulder-Neck Study group.

    abstract::The present paper presents the relationship between the total body-pain (TBP) score, defined as the total number of areas shaded on a pain drawing, and the pain from one area, the Shoulder-Neck (SN), among subjects in or out of full-time gainful work respectively. Furthermore, relationships between pain-score, self-ex...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/S0304-3959(99)00053-6

    authors: Ektor-Andersen J,Isacsson SO,Lindgren A,Ørbæk P,Malmö Shoulder-Neck Study group.

    更新日期:1999-09-01 00:00:00

  • Chronic secondary hypersensitivity of dorsal horn neurones following inflammation of the knee joint.

    abstract::Intra-articular injection of Freund's complete adjuvant (FCA) into the rat knee joint produces a swelling of the joint and long lasting hypersensitivity. In this study we have used this model and in vivo electrophysiology to investigate the time course of spinal changes underlying chronic secondary hypersensitivity, b...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/j.pain.2007.03.006

    authors: Martindale JC,Wilson AW,Reeve AJ,Chessell IP,Headley PM

    更新日期:2007-12-15 00:00:00

  • Central pruritus. Case report.

    abstract::An 82-year-old woman experienced generalized pruritus not due to skin or systemic disease. Scratching the skin with a needle induced a crisis of intense pruritus, insensitive to any drug. The pruritus had the characteristics of a central sensation. ...

    journal_title:Pain

    pub_type: 杂志文章

    doi:10.1016/0304-3959(91)90055-3

    authors: Procacci P,Maresca M

    更新日期:1991-06-01 00:00:00