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Essential role of the small GTPase Rac in disease resistance of rice.

Abstract：

:Production of reactive oxygen intermediates (ROI) and a form of programmed cell death called hypersensitive response (HR) are often associated with disease resistance of plants. We have previously shown that the Rac homolog of rice, OsRac1, is a regulator of ROI production and cell death in rice. Here we show that the constitutively active OsRac1 (i) causes HR-like responses and greatly reduces disease lesions against a virulent race of the rice blast fungus; (ii) causes resistance against a virulent race of bacterial blight; and (iii) causes enhanced production of a phytoalexin and alters expression of defense-related genes. The dominant-negative OsRac1 suppresses elicitor-induced ROI production in transgenic cell cultures, and in plants suppresses the HR induced by the avirulent race of the fungus. Taken together, our findings strongly suggest that OsRac1 has a general role in disease resistance of rice.

journal_name

Proc Natl Acad Sci U S A

journal_title

Proceedings of the National Academy of Sciences of the United States of America

authors

Ono E,Wong HL,Kawasaki T,Hasegawa M,Kodama O,Shimamoto K

doi

10.1073/pnas.021273498

keywords:

subject

Has Abstract

pub_date

2001-01-16 00:00:00

pages

759-64

issue

2

eissn

0027-8424

issn

1091-6490

pii

021273498

journal_volume

98

pub_type

杂志文章

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