Mechanisms of angiotensin II-induced platelet-derived growth factor gene expression.

abstract：:The present study was designed to investigate the possible effects of chronic dichlorvos exposure on the various aspects of calcium homeostasis in rat brain. Chronic dichlorvos administration caused significant rise in the intrasynaptosomal calcium levels. The activity of major calcium expelling enzyme i.e. Ca2+ATPase...

journal_title：Molecular and cellular biochemistry

authors： Raheja G,Gill KD

更新日期：2002-03-01 00:00:00

abstract：:Phosphorylases (EC 2.4.1.1) from potato and rabbit muscle are similar in many of their structural and kinetic properties, despite differences in regulation of their enzyme activity. Rabbit muscle phosphorylase is subject to both allosteric and covalent controls, while potato phosphorylase is an active species without ...

journal_title：Molecular and cellular biochemistry

authors： Fukui T,Shimomura S,Nakano K

更新日期：1982-02-19 00:00:00

abstract：:Uterine leiomyoma (ULM) is the most common gynecological benign tumor that is affecting around 20-50 % of women over the age of 30. Although its molecular pathogenesis is still unknown, ULM has a multifactorial etiology determined by both genetics and environmental factors. The present study was designed to find out w...

journal_title：Molecular and cellular biochemistry

authors： Ates O,Demirturk F,Toprak M,Sezer S

更新日期：2013-03-01 00:00:00

abstract：:The uptake of glucose and gluconate is under inductive control in Pseudomonas putida. Glucose, gluconate, and 2-ketogluconate were each good nutritional inducers of these transport abilities. Glucose and gluconate uptake obeyed saturation kinetics: the apparent Km for glucose was 6 mM and that for gluconate was 0.5 mM...

journal_title：Molecular and cellular biochemistry

authors： Vicente M,Pedro MA,Torrontegui G,Cánovas JL

更新日期：1975-04-30 00:00:00

abstract：:Autoantibodies (AABs) against the second extracellular loop of the beta1-receptor (beta1(II)-AABs) are found as a pathogenic driver in patients with idiopathic dilated cardiomyopathy, Chagas cardiomyopathy, peripartum cardiomyopathy, and myocarditis, and have been increasingly seen as a treatment target. We recently i...

journal_title：Molecular and cellular biochemistry

authors： Haberland A,Wallukat G,Berg S,Schulz AM,Freyse EJ,Vetter R,Salzsieder E,Müller J,Kreutz R,Schimke I

更新日期：2014-08-01 00:00:00

abstract：:In this study, indirect immunofluorescence labeling was used to examine the cellular dynamic distribution of Thr11 phosphorylated H3 at mitosis in MCF-7 cells. The Thr11 phosphorylation was observed beginning at prophase at centromeres. Upon progression of mitosis, fluorescence signal was enhanced in the central regio...

journal_title：Molecular and cellular biochemistry

authors： Zhou H,Li D,Song L,Liu R,Chen J,Huang X

更新日期：2008-04-01 00:00:00

abstract：:The major protein in the sarcoplasmic reticulum (SR) membrane is the Ca2+ transporting ATPase which carries out active Ca2+ pumping at the expense of ATP hydrolysis. The aim of this work was to elucidate the mechanisms by which oxidative stress induced by Fenton's reaction (Fe(2+)+H2O2-->HO.+OH-+Fe3+) alters the funct...

journal_title：Molecular and cellular biochemistry

authors： Castilho RF,Carvalho-Alves PC,Vercesi AE,Ferreira ST

更新日期：1996-06-21 00:00:00

abstract：:Patients with non-ketotic hyperglycinemia (NKH) present severe neurological symptoms and brain abnormalities involving cerebellum. Although the pathomechanisms underlying the cerebellum damage have not been studied, high tissue levels of glycine (GLY), the biochemical hallmark of this disorder have been suggested to c...

journal_title：Molecular and cellular biochemistry

authors： Moura AP,Grings M,Marcowich GF,Bumbel AP,Parmeggiani B,de Moura Alvorcem L,Wajner M,Leipnitz G

更新日期：2014-10-01 00:00:00

abstract：:The present study was aimed at addressing the effect of hyperglycemia on antioxidant enzymes. The expression of catalase, superoxide dismutase and glutathione peroxidase, the three primary scavenger enzymes involved in detoxifying reactive oxygen species has been evaluated in the renal cortex of rats after 6 weeks of ...

journal_title：Molecular and cellular biochemistry

authors： Limaye PV,Raghuram N,Sivakami S

更新日期：2003-01-01 00:00:00

abstract：:Higher order chromatin degradation (HOCD) is a stepwise dismantling of the genome through the excision of chromatin loops and their oligomers at matrix attachment regions (MARs) during the early stages of programmed cell death. Although HOCD ultimately leads to the inactivation of the genome and cell death, a partial ...

journal_title：Molecular and cellular biochemistry

authors： Banaszewska M,Konat GW

更新日期：2006-01-01 00:00:00

abstract：:Serratia marcescens utilizes two types of quorum-sensing signal molecules: N-acyl homoserine lactones and furanosyl borate diester (AI-2). S-adenosylmethionine synthetase (METK), S-adenosylhomocysteine nucleosidase (PFS), and S-ribosylhomocysteinase (LUXS) are three key enzymes in the biosynthetic pathway leading to A...

journal_title：Molecular and cellular biochemistry

authors： Zhu H,Shen YL,Wei DZ,Zhu JW

更新日期：2008-08-01 00:00:00

abstract：:Based on sequence relationships the cytoplasmic fatty acid-binding proteins (FABPs) of mammalian origin are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. Highly conserved sequences of FABPs within the same type correlate with immunological crossreactivities. Isoforms of...

journal_title：Molecular and cellular biochemistry

authors： Spener F,Unterberg C,Börchers T,Grosse R

更新日期：1990-10-15 00:00:00

abstract：:MERRF (myoclonic epilepsy with ragged-red fibers) is a severe, multisystem disorder characterized by myoclonus, seizures, progressive cerebellar syndrome, muscle weakness, and the presence of ragged-red fibers in the muscle biopsy. MERRF is associated with heteroplasmic point mutations, either A8344G or T8356C, in the...

journal_title：Molecular and cellular biochemistry

authors： Masucci JP,Schon EA,King MP

更新日期：1997-09-01 00:00:00

abstract：:Both idiopathic restrictive cardiomyopathy (IRCM) and hypertrophic cardiomyopathy (HCM) are part of the same disease spectrum and are due to sarcomeric gene mutations. A patient with restrictive physiology without left ventricular hypertrophy (LVH) would be diagnosed as IRCM, while one with LVH would be diagnosed as H...

journal_title：Molecular and cellular biochemistry

authors： Rai TS,Ahmad S,Ahluwalia TS,Ahuja M,Bahl A,Saikia UN,Singh B,Talwar KK,Khullar M

更新日期：2009-11-01 00:00:00

abstract：:Limited proteolysis of rabbit muscle phosphorylase kinase catalyzed by chymotrypsin generates a 33 kD product whose kinase activity is independent of both calcium and pH over the range of 6.8 to 8.3 (Malencik, D.A. & Fischer, E.H. Calcium and Cell Function III: 161-188, 1982). This active preparation consists of three...

journal_title：Molecular and cellular biochemistry

authors： Malencik DA,Zhao Z,Anderson SR

更新日期：1993-11-01 00:00:00

abstract：:In addition of being an important inflammatory biomarker and a risk factor for cardiovascular disease, much evidence indicates that the C-reactive protein (CRP) contributes to the atherosclerosis development process. This plasmatic protein synthesized by hepatocytes in response to inflammation and tissue injury induce...

journal_title：Molecular and cellular biochemistry

authors： Cossette É,Cloutier I,Tardif K,DonPierre G,Tanguay JF

更新日期：2013-01-01 00:00:00

abstract：:The ubiquitin specific peptidase 22 (USP22) is a positive regulator of the growth of tumors. However, little is known about the impact of USP22 knockdown on the growth of human bladder cells. In the present study, we designed a series of asymmetric interfering RNAs (aiRNAs) and compared the efficacy of aiRNA and conve...

journal_title：Molecular and cellular biochemistry

authors： Lv L,Xiao XY,Gu ZH,Zeng FQ,Huang LQ,Jiang GS

更新日期：2011-01-01 00:00:00

abstract：UNLABELLED:Since recent findings indicate the involvement of G-proteins in the mechanism of ischaemic preconditioning (PC), the present study was aimed to investigate the role of adrenergic mechanisms, such as G-proteins and stimulation of adrenergic receptors, in this phenomenon. For this purpose, isolated Langendorff...

journal_title：Molecular and cellular biochemistry

authors： Ravingerová T,Pyne NJ,Parratt JR

更新日期：1995-06-07 00:00:00

abstract：:MicroRNAs have been implicated in regulating diverse cellular pathways. Emerging evidence indicates that miR-143 plays causal roles in cancer tumorigenesis as a tumor suppress gene; however, its role in prostate cancer tumorigenesis remains largely unknown. The aims of this study were to verify the effect of miR-143 o...

journal_title：Molecular and cellular biochemistry

authors： Xu B,Niu X,Zhang X,Tao J,Wu D,Wang Z,Li P,Zhang W,Wu H,Feng N,Wang Z,Hua L,Wang X

更新日期：2011-04-01 00:00:00

abstract：:Colorectal cancer (CRC) is a major cause of death worldwide. Novel non-invasive, high diagnostic value screening test is urgently needed to improve survival rate, treatment and prognosis. Stable, small, circulating microRNA (miRNA) offers unique opportunities for the early diagnosis of several diseases. It acts as tum...

journal_title：Molecular and cellular biochemistry

authors： Sabry D,El-Deek SEM,Maher M,El-Baz MAH,El-Bader HM,Amer E,Hassan EA,Fathy W,El-Deek HEM

更新日期：2019-04-01 00:00:00

abstract：:Human glomerular mesangial cells (HMCs) have a finite lifespan and eventually enter irreversible growth arrest known as cellular senescence which is thought to contribute to kidney aging and age-related kidney disorders, such as chronic kidney disease. The signal transducer and activator of transcription 1 (STAT1) is ...

journal_title：Molecular and cellular biochemistry

authors： Jiao S,Meng F,Zhang J,Yang X,Zheng X,Wang L

更新日期：2012-06-01 00:00:00

abstract：:Cyclophosphamide (CP) is one of the widely used anticancer agents; however, it has serious deleterious effects on normal host cells due to its nonspecific action. The essential trace element Selenium (Se) is suggested to have chemopreventive and chemotherapeutic efficacy and currently used in pharmaceutical formulatio...

journal_title：Molecular and cellular biochemistry

authors： Bhattacharjee A,Basu A,Biswas J,Sen T,Bhattacharya S

更新日期：2017-01-01 00:00:00

abstract：:Long non-coding RNAs (lncRNAs) are known as crucial regulators in the development of OC. In the current study, we aim to explore the function and molecular mechanism of lncRNA DLEU1 in OC. Quantitative real-time polymerase chain reaction (qRT-PCR) was applied to determine the expression of DLEU1, miR-429, and TFAP2A i...

journal_title：Molecular and cellular biochemistry

authors： Xu H,Wang L,Jiang X

更新日期：2020-11-10 00:00:00

abstract：:We found out a new protein from natural actomyosin prepared from adductor muscle of Hokki clam, bivalve shell. We isolated this protein and determined some properties. It has a large molecular weight (230 kDa) and the star diagram of amino acid composition was very similar to that of paramyosin (110 kDa). When this pr...

journal_title：Molecular and cellular biochemistry

authors： Yazawa Y,Kamidochi M

更新日期：1999-01-01 00:00:00

abstract：:Hyperlipidemia is a well-known risk factor for atherosclerosis and statins are widely used to treat patients with elevated levels of lipids in their plasma. Notwithstanding the proven benefits of statin drugs on both primary and secondary prevention of heart disease, the high cost of statin treatment, in addition to p...

journal_title：Molecular and cellular biochemistry

authors： Man RY,Lynn EG,Cheung F,Tsang PS,O K

更新日期：2002-04-01 00:00:00

abstract：:The pyridine nucleotides have important non-redox activities as cellular effectors and metabolic regulators [1-3]. The enzyme-catalyzed cleavage of the nicotinamide-ribosyl bond of NAD+ and the attendant delivery of the ADPRibosyl moiety to acceptors is central to these many diverse biological activities. Included are...

journal_title：Molecular and cellular biochemistry

authors： Oppenheimer NJ

更新日期：1994-09-01 00:00:00

abstract：:Enzymes have proven to be sensitive and versatile labels for immunochemical assays. The sensitivity of an enzyme label stems from its extraordinary catalytic power which in turn provides a great amplification of signals. Its versatility, however, stems from the fact that enzyme activity can be modulated by a number of...

journal_title：Molecular and cellular biochemistry

authors： Ngo TT,Lenhoff HM

更新日期：1982-04-16 00:00:00

abstract：:Methylxanthines are widely consumed because of their stimulating effect primarily on the central nervous system. Their diuretic and respiratory stimulant action is used in clinical medicine. L-Arginine metabolism in the brain is very important for normal brain function. In addition to brain protein synthesis, arginine...

journal_title：Molecular and cellular biochemistry

authors： Nikolic J,Bjelakovic G,Stojanovic I

更新日期：2003-02-01 00:00:00

abstract：:The effect of anti-regucalcin monoclonal antibody on neutral phoshatase activity in rat liver cytosol was investigated. Phosphotyrosine, phosphoserine, and phosphothreonine were used as the substrate toward phosphatase assay. Liver cytosolic phosphatase activity with three phosphoaminoacids was significantly increased...

journal_title：Molecular and cellular biochemistry

authors： Omura M,Yamaguchi M

更新日期：1999-07-01 00:00:00

abstract：:Alpha-fetoprotein (AFP) for long was known as immunomodulator and tumor marker having multifaceted actions on the activity of normal and transformed cells. In present study, we have investigated the involvement of AFP in regulation of THP-1 cell line invasion and underlying mechanisms. Treatment with human recombinant...

journal_title：Molecular and cellular biochemistry

authors： Zubkova E,Semenkova L,Dudich E,Dudich I,Parfyonova Y,Menshikov M

更新日期：2013-07-01 00:00:00