T1 lung cancer on CT: frequency of extrathoracic metastases.

Abstract:

PURPOSE:To determine the frequency of extrathoracic metastases in T1 non-small-cell lung cancer. METHOD:Ninety patients with T1 lung cancer identified on CT were included. Extrathoracic metastases were evaluated at the time of initial diagnosis and during a 1-year follow-up study. The frequency of metastases was compared in terms of cell type (squamous or nonsquamous), size (<2 cm or >2 cm), and the initial CT findings of the tumor. RESULTS:Extrathoracic metastases were identified in 12 (13%) of 90 patients at the time of diagnosis and in 10 patients at the 1-year follow-up study (total, 22 of 90 [24%] patients). Tumors with ground-glass opacity on CT were associated with a significantly lower prevalence of metastases (p = 0.042). The area of ground-glass opacity was seen in 1 of 13 (85%) patients with bronchioloalveolar carcinoma and in 12 of 53 (23%) patients with adenocarcinoma other than bronchioloalveolar carcinoma (p < 0.001). There was no significant difference in the prevalence of metastases between squamous and nonsquamous cell carcinoma, between tumors smaller than 2 cm (n = 17) and larger than 2 cm in diameter (n = 73) and between tumors with or without mediastinal nodal metastases (p>0.05). CONCLUSION:Extrathoracic metastases were apparent at the initial examination in 13% of patients and at the 1-year follow-up examination in 11% of patients. The prevalence is significantly lower in tumors with ground-glass opacity.

journal_name

J Comput Assist Tomogr

authors

Jung KJ,Lee KS,Kim H,Kwon OJ,Kim J,Shim YM,Kim TS

doi

10.1097/00004728-200009000-00008

keywords:

subject

Has Abstract

pub_date

2000-09-01 00:00:00

pages

711-8

issue

5

eissn

0363-8715

issn

1532-3145

pii

00004728-200009000-00008

journal_volume

24

pub_type

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