Assessing human cardiac allograft rejection using MRI with Gd-DOTA.

Abstract:

:To explore the potential role of MRI in detecting cardiac allograft rejection in transplant recipients using gadolinium tetraazacyclododecane tetraacetic acid (Gd-DOTA) for contrast enhancement, we examined 7 normal healthy volunteers and 39 patients separated into three groups according to histological findings. Quantitative myocardial enhancement (ME), expressed as the ratio of maximum signal intensity after intravenous Gd-DOTA injection to signal intensity before intravenous injection of Gd-DOTA, was significantly lower for patients without histological rejection (n = 14; regional ME = 83 +/- 41%; mean ME = 53 +/- 24%) when compared with patients with grade 1 histological rejection (n = 18; regional ME = 122 +/- 20%, p = 0.02; mean ME = 70 +/- 14%, p < 0.05) and with patients with grade 2 or 3 rejection (n = 7; regional ME = 135 +/- 44%, p = 0.02; mean ME = 81 +/- 27%, p < 0.05). Myocardial enhancement was not significantly different in patients with grade 1 histological rejection compared with patients with grade 2 or 3 rejection. Because predominant focal areas of ME were observed in all patients, regional ME seemed a better measurement than mean ME to distinguish focal histological changes when the rejection process is beginning. More sophisticated software analysis is necessary to quantify and map high ME to establish the exact relationship between the extent of edema and the severity of rejection.

journal_name

J Comput Assist Tomogr

authors

Mousseaux E,Farge D,Guillemain R,Bruneval P,Vulser C,Couétil JP,Carpentier A,Gaux JC

doi

10.1097/00004728-199303000-00012

subject

Has Abstract

pub_date

1993-03-01 00:00:00

pages

237-44

issue

2

eissn

0363-8715

issn

1532-3145

journal_volume

17

pub_type

杂志文章
  • The spotted spleen: CT and clinical correlation in a tertiary care center.

    abstract:PURPOSE:The goal of our study was to examine the prevalence of multiple hypodense splenic nodules and their associated diagnoses and to correlate CT appearance with clinical presentation and diagnosis. METHOD:Records of all patients undergoing contrast-enhanced CT from July 1994 through September 1997 were reviewed. C...

    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章

    doi:10.1097/00004728-199809000-00005

    authors: Warshauer DM,Molina PL,Worawattanakul S

    更新日期:1998-09-01 00:00:00

  • Squamous cell carcinoma of the anus and rectum in homosexual men: CT findings.

    abstract:OBJECTIVE:Homosexual men are at risk for a variety of infectious and neoplastic diseases of the anus and rectum, many of which have been reported in the radiologic literature. The purpose of this study was to describe the CT findings in homosexual men with squamous cell carcinoma of the anus and rectum, a topic that ha...

    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章

    doi:10.1097/00004728-199411000-00013

    authors: Radin DR

    更新日期:1994-11-01 00:00:00

  • "Incomplete ring" sign: a simple method for CT detection of spondylolysis.

    abstract::Multiple authors have pointed out the difficulty of detecting spondylolysis with lumbar CT. A simple method to detect spondylolysis on lumbar CT is described. Identifying one intact cortical ring for each vertebra absolutely excludes the diagnosis obviating the time-consuming need to search each image looking for posi...

    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章

    doi:

    authors: Langston JW,Gavant ML

    更新日期:1985-07-01 00:00:00

  • Computed tomography of the craniocervical junction in rheumatoid arthritis.

    abstract::Thirty-three patients with rheumatoid arthritis had computed tomographic examination of the craniocervical junction. This demonstrated soft tissue features which have not previously been described in published reports. A low attenuation lesion between the odontoid and the transverse ligament shown in 11 patients was c...

    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章

    doi:10.1097/00004728-198302000-00006

    authors: Castor WR,Miller JD,Russell AS,Chiu PL,Grace M,Hanson J

    更新日期:1983-02-01 00:00:00

  • The diagnostic utility of HASTE MRI in the evaluation of acute cholecystitis. Half-Fourier acquisition single-shot turbo SE.

    abstract:PURPOSE:The purpose of this study was twofold: (a) to determine the significance of high signal intensity surrounding the gallbladder as seen on T2-weighted HASTE (half-Fourier acquisition single shot turbo SE) MR images in patients with acute cholecystitis and (b) to determine the sensitivity of T2-weighted HASTE MR i...

    journal_title:Journal of computer assisted tomography

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00004728-199807000-00025

    authors: Regan F,Schaefer DC,Smith DP,Petronis JD,Bohlman ME,Magnuson TH

    更新日期:1998-07-01 00:00:00

  • Effect of Coronary Artery Calcification Score by Lifestyle and Correlation With Coronary Artery Stenosis by Multidetector Computed Tomography.

    abstract:OBJECTIVE:This study examined the effect of coronary artery calcification score by lifestyle and correlation with coronary artery stenosis in persons who underwent coronary artery computed tomography (CT) angiography among health examinees for heart diseases in Korea. METHODS AND MATERIALS:The study included 506 subje...

    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章

    doi:10.1097/RCT.0000000000000497

    authors: Lee SH,Cho JH,Kim HE,Kim SC

    更新日期:2017-03-01 00:00:00

  • Radiation dose reduction with chest computed tomography using adaptive statistical iterative reconstruction technique: initial experience.

    abstract:PURPOSE:To assess radiation dose reduction and image quality for weight-based chest computed tomographic (CT) examination results reconstructed using adaptive statistical iterative reconstruction (ASIR) technique. MATERIALS AND METHODS:With local ethical committee approval, weight-adjusted chest CT examinations were p...

    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章

    doi:10.1097/RCT.0b013e3181b26c67

    authors: Prakash P,Kalra MK,Digumarthy SR,Hsieh J,Pien H,Singh S,Gilman MD,Shepard JA

    更新日期:2010-01-01 00:00:00

  • Detection of Bone Marrow Edema Pattern With Dual-Energy Computed Tomography of the Pig Mandible Treated With Radiotherapy and Surgery Compared With Magnetic Resonance Imaging.

    abstract:OBJECTIVE:The aim of the study was to investigate the accuracy of dual-energy computed tomography (DECT) compared with magnetic resonance (MR) imaging for the detection of edema of the mandible. MATERIALS AND METHODS:Fifteen adult Göttingen mini pigs received irradiation to the mandible with an equivalent dose of 0, 2...

    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章

    doi:10.1097/RCT.0000000000000559

    authors: Poort LJ,Stadler AAR,Ludlage JHB,Hoebers FJP,Kessler PAWH,Postma AA

    更新日期:2017-07-01 00:00:00

  • The target sign: a CT finding in tumors of the corpus callosum.

    abstract::An unusual computed tomography finding, the "target sign," is demonstrated in a patient with a corpus callosum tumor mass extending to the right lateral ventricle. The central low attenuation of the "target" is produced by the isolated part of the dilated lateral ventricle surrounded by tumor tissue, the dense area of...

    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章

    doi:

    authors: El Gammal T,McDaniel FE

    更新日期:1979-08-01 00:00:00

  • Proposed system for ultrafast computed tomography.

    abstract::Construction of a new ultrafast scanner system suitable for dynamic computed tomography is now under consideration, with development soon to begin. This system will be characterized by an electronically controlled X-ray generator with wide angle double diffraction, which will permit transverse axial images to be taken...

    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章

    doi:10.1097/00004728-197710000-00017

    authors: Iinuma TA,Tateno Y,Umegaki Y,Watanabe E

    更新日期:1977-10-01 00:00:00

  • Retrodural cysts bridging a bilateral lumbar spondylolysis: a report of two symptomatic cases.

    abstract::We report the MR features in two patients presenting with symptomatic thecal impingement by posterior epidural cysts linking a bilateral lumbar spondylolysis. Large fluid-filled channels bridging the ruptured partes interarticulares were present in spite of the absence of significant arthritic changes within the adjac...

    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章

    doi:10.1097/00004728-199907000-00008

    authors: Duprez T,Mailleux P,Bodart A,Coulier B,Malghem J,Maldague B

    更新日期:1999-07-01 00:00:00

  • Comparison of 3-segmentation techniques for intraventricular and intracerebral hemorrhages in unenhanced computed tomography scans.

    abstract:OBJECTIVES:The Clot Lysis Evaluating Accelerated Resolution of Intraventricular Hemorrhage Trial phase III is a multicenter, randomized clinical trial in the management and treatment of subjects with small intracerebral hemorrhage and large intraventricular hemorrhage. Accurate localization, segmentation, and quantific...

    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1097/RCT.0b013e318245c1fa

    authors: KN BP,Hu J,Morgan TC,Hanley D,Nowinski WL

    更新日期:2012-01-01 00:00:00

  • Contrast-related flow phenomena mimicking pathology on thoracic computed tomography.

    abstract::Flow phenomena occurring after the bolus injection of contrast material can simulate the presence of pathology on thoracic computed tomography. In a review of 50 dynamic scans performed after contrast medium injection, apparent filling defects in the superior vena cava were seen in 46. In four cases, retrograde fillin...

    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章

    doi:10.1097/00004728-198206000-00004

    authors: Godwin JD,Webb WR

    更新日期:1982-06-01 00:00:00

  • Semiautomated ROI analysis in dynamic MR studies. Part II: Application to renal function examination.

    abstract::Fast MR techniques and the application of water-soluble contrast agents allow the simultaneous examination of renal morphology and the functional aspects of glomerular filtration using bolus injections of Gd-DTPA. Spatial resolution is sufficient to resolve individual renal pyramids, but the quantitative examination o...

    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章

    doi:10.1097/00004728-199109000-00002

    authors: von Schulthess GK,Kuoni W,Gerig G,Wüthrich R,Duewell S,Krestin G

    更新日期:1991-09-01 00:00:00

  • Detection of thyroid pyramidal lobe by ultrasound versus computed tomography: a single-center study.

    abstract:OBJECTIVE:The prevalence and features of the thyroid pyramidal lobe (TPL) on computed tomography (CT) have been reported, but no ultrasound (US) study has been found. The purposes of the current study were to assess the sonographic prevalence and features of TPLs and to compare the US and CT parameters of TPLs. METHOD...

    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章

    doi:10.1097/RCT.0000000000000054

    authors: Kim KS,Kim DW,Sung JY

    更新日期:2014-05-01 00:00:00

  • Nasal orientation device to control head movement during CT and MR studies.

    abstract::Cooperative patients can often keep still during a long examination of the brain provided that they are given cues about their position in space. In a U-shaped head support, the only movements likely are rotation in the sagittal or transverse planes. These can be detected by a nasal orientation device (NOD), simply a ...

    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章

    doi:10.1097/00004728-199001000-00038

    authors: Tofts PS,Kermode AG,MacManus DG,Robinson WH

    更新日期:1990-01-01 00:00:00

  • Assessment of the tracer delay effect in whole-brain computed tomography perfusion: results in patients without known neuroanatomic abnormalities.

    abstract:OBJECTIVE:Whole-brain computed tomography perfusion (CTP) data sets generated by tracer delay-insensitive singular value decomposition plus (SVD+) and standard singular value decomposition (sSVD) deconvolution algorithms were evaluated to quantify relatedness and discrepancies in CTP results. METHODS:Twenty females wi...

    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章

    doi:10.1097/RCT.0b013e31828004bb

    authors: Hanson EH,Roach CJ,Day KJ,Peters KR,Bradley WG Jr,Ghosh K,Patton PW,McMurray RC,Orrison WW Jr

    更新日期:2013-03-01 00:00:00

  • Colorectal mucinous carcinoma: findings on MRI.

    abstract:PURPOSE:The purpose of this work was to define the characteristic MR features of colorectal mucinous carcinomas and to correlate the mucin pool with the signal intensity of this tumor. METHOD:MRI of 12 cases of pathologically proven colorectal carcinoma containing mucin was evaluated. We analyzed the signal intensity ...

    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章

    doi:10.1097/00004728-199903000-00021

    authors: Kim MJ,Huh YM,Park YN,Kim NK,Kim DJ,Chung JJ,Kim WH,Yoo HS,Lee JT

    更新日期:1999-03-01 00:00:00

  • Value of computed tomography for the diagnosis of a ruptured eye.

    abstract::The diagnosis of scleral perforation of the globe following ocular trauma is often obvious on physical examination, but occult perforations occur frequently. In addition to locating intraorbital foreign bodies and associated facial bone fractures, computed tomography of the orbit can suggest an occult scleral rupture....

    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章

    doi:10.1097/00004728-198310000-00022

    authors: Sevel D,Krausz H,Ponder T,Centeno R

    更新日期:1983-10-01 00:00:00

  • Incidental findings are frequent in young healthy individuals undergoing magnetic resonance imaging in brain research imaging studies: a prospective single-center study.

    abstract:OBJECTIVE:There is an ongoing debate about how to handle incidental findings (IF) detected in healthy individuals who participate in research-driven magnetic resonance imaging (MRI) studies. There are currently no established guidelines regarding their management. METHODS:We prospectively assessed the frequency of IF ...

    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章

    doi:10.1097/RCT.0b013e3181d9c2bb

    authors: Hartwigsen G,Siebner HR,Deuschl G,Jansen O,Ulmer S

    更新日期:2010-07-01 00:00:00

  • Right ventricle shape and contraction patterns and relation to magnetic resonance imaging findings.

    abstract:OBJECTIVE:To analyze and to describe the shape and contraction of the normal right ventricle (RV) as visualized by magnetic resonance imaging (MRI). METHODS:Thirty normal volunteers were imaged using cine MRI in axial, short-axis, and long-axis planes. The shape and contraction of the RV were qualitatively evaluated. ...

    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章

    doi:10.1097/01.rct.0000179596.86221.38

    authors: Fritz J,Solaiyappan M,Tandri H,Bomma C,Genc A,Claussen CD,Lima JA,Bluemke DA

    更新日期:2005-11-01 00:00:00

  • Computer assisted tomography of orbital lesions in Wegener's granulomatosis.

    abstract::The orbital lesions in six patients with Wegener's granulomatosis were studied by computer assisted tomography (CAT). Four patients had active orbital disease and proptosis, and each was found to have orbital masses accompanied by varying degrees of bone and sinus destruction. Two additional patients with histories of...

    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章

    doi:10.1097/00004728-197801000-00006

    authors: Vermess M,Haynes BF,Fauci AS,Wolff SM

    更新日期:1978-01-01 00:00:00

  • Gadolinium DTPA enhanced MR imaging of ACTH-secreting microadenomas of the pituitary gland.

    abstract::Gadolinium diethylenetriamine pentaacetic acid (DTPA) enhanced magnetic resonance imaging was performed in eight patients with Cushing disease and surgically proven pituitary microadenomas. A 1.5 T scanner was used with 3 mm contiguous slices. Short repetition times (TR), short echo times (TE), and long TR, long TE se...

    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章

    doi:10.1097/00004728-198809010-00002

    authors: Doppman JL,Frank JA,Dwyer AJ,Oldfield EH,Miller DL,Nieman LK,Chrousos GP,Cutler GB Jr,Loriaux DL

    更新日期:1988-09-01 00:00:00

  • Biplane computed tomography of intracranial meningiomas with extracranial extension.

    abstract::Fifteen of 130 intracranial meningiomas evaluated by biplane computed tomography (CT)--axial transverse and coronal--were found to have direct extracranial extension. These include five pterional meningiomas en plaque with extension to the orbit and temporal fossa; three subfrontal meningiomas invading the paranasal s...

    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章

    doi:10.1097/00004728-198008000-00014

    authors: Nakagawa H,Lusins JO

    更新日期:1980-08-01 00:00:00

  • Focal obstructive nephrogram: an unusual CT appearance of a transitional cell carcinoma.

    abstract::The unusual CT appearances of a renal neoplasm, which we have described as a "focal" obstructive nephrogram secondary to transitional cell carcinoma, is reported. An explanation of the appearance is postulated. ...

    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章

    doi:

    authors: Breatnach ES,Stanley RJ,Lloyd K

    更新日期:1984-10-01 00:00:00

  • Pedunculated bronchogenic cyst mimicking pleural lesion.

    abstract::We report a rare case of a bronchogenic cyst presenting as a pleural nodule. CT and MRI demonstrated a well circumscribed, homogeneous lesion located on the pleural surface apart from the mediastinum. It was proven to be a bronchogenic cyst localized between the parietal and visceral pleurae and connected with the med...

    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章

    doi:10.1097/00004728-200007000-00012

    authors: Yoshioka N,Minami M,Inoue Y,Kawauchi N,Nakajima J,Oka T,Yoshikawa K,Ohtomo K

    更新日期:2000-07-01 00:00:00

  • Case Report. CT and US features of renal matrix stones with calcified center.

    abstract::We report imaging findings of renal matrix stones in a patient with congenital ureteropelvic junction obstruction associated with urinary tract infection. The stones were composed of a calcified center and a non-calcified peripheral matrix that was slightly high attenuated on CT and nonshadowing on US. ...

    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章

    doi:10.1097/00004728-199605000-00015

    authors: Kim SH,Lee SE,Park IA

    更新日期:1996-05-01 00:00:00

  • Direct invasion of urinary bladder from sigmoid colon cancer: CT findings.

    abstract::Radiological findings in three cases of sigmoid colon carcinoma invading the urinary bladder are reported. An irregular spiculated margin or nodular indentations in region of bladder dome were seen on intravenous urography. A soft tissue mass contiguous with an irregularly thickened urinary bladder wall and a circumfe...

    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章

    doi:10.1097/00004728-199209000-00007

    authors: Kim SH,Na DG,Choi BI,Han JK,Han MC

    更新日期:1992-09-01 00:00:00

  • Diffusion magnetic resonance imaging of solid vestibular schwannomas.

    abstract::Six patients with solid vestibular schwannomas were studied by diffusion magnetic resonance imaging to assess if this modality adds new information for these tumors, because there is no previous report in the relevant literature. The sizes of the tumors ranged from 2.2 to 4.7 cm with respect to their largest diameters...

    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章

    doi:10.1097/00004728-200303000-00024

    authors: Sener RN

    更新日期:2003-03-01 00:00:00

  • Azygos continuation of inferior vena cava: CT appearance.

    abstract::Two cases demonstrating the computed tomographic appearance of azygos continuation of the inferior vena cava (IVC) are presented. One is associated with a retroaortic left renal vein and the other with a duplicated IVC. An enlarged azygos vein should not be confused with retrocrural lymphadenopathy or a mediastinal ma...

    journal_title:Journal of computer assisted tomography

    pub_type: 杂志文章

    doi:10.1097/00004728-198006000-00015

    authors: Breckenridge JW,Kinlaw WB

    更新日期:1980-06-01 00:00:00