Abstract:
PURPOSE:First-pass perfusion magnetic resonance imaging (MRI) is a promising technique for detecting ischemic heart disease. However, the diagnostic value of the method is limited by the low spatial coverage, resolution, signal-to-noise ratio (SNR), and cardiac motion-related image artifacts. A combination of sliding window and conjugate-gradient HighlY constrained back-PRojection reconstruction (SW-CG-HYPR) method has been proposed in healthy volunteer studies to reduce the acquisition window for each slice while maintaining the temporal resolution of 1 frame per heartbeat in myocardial perfusion MRI. This method allows for improved spatial coverage, resolution, and SNR. METHODS:In this study, we use a controlled animal model to test whether the myocardial territory supplied by a stenotic coronary artery can be detected accurately by SW-CG-HYPR perfusion method under pharmacological stress. RESULTS:Results from 6 mongrel dogs (15-25 kg) studies demonstrate the feasibility of SW-CG-HYPR to detect regional perfusion defects. Using this method, the acquisition time per cardiac cycle was reduced by a factor of 4, and the spatial coverage was increased from 2 to 3 slices to 6 slices as compared with the conventional techniques including both turbo-Fast Low Angle Short (FLASH) and echoplanar imaging (EPI). The SNR of the healthy myocardium at peak enhancement with SW-CG-HYPR (12.68 ± 2.46) is significantly higher (P < 0.01) than the turbo-FLASH (8.65 ± 1.93) and EPI (5.48 ± 1.24). The spatial resolution of SW-CG-HYPR images is 1.2 × 1.2 × 8.0 mm, which is better than the turbo-FLASH (1.8 × 1.8 × 8.0 mm) and EPI (2.0 × 1.8 × 8.0 mm). CONCLUSIONS:Sliding-window CG-HYPR is a promising technique for myocardial perfusion MRI. This technique provides higher image quality with respect to significantly improved SNR and spatial resolution of the myocardial perfusion images, which might improve myocardial perfusion imaging in a clinical setting.
journal_name
J Comput Assist Tomogrjournal_title
Journal of computer assisted tomographyauthors
Ge L,Kino A,Lee D,Dharmakumar R,Carr JC,Li Ddoi
10.1097/RCT.0b013e3181e9e9ddsubject
Has Abstractpub_date
2010-09-01 00:00:00pages
684-8issue
5eissn
0363-8715issn
1532-3145pii
00004728-201009000-00008journal_volume
34pub_type
杂志文章abstract::Forty-four consecutive patients with laryngeal carcinomas presenting at different stages of the disease were investigated by magnetic resonance (MR) imaging. Twelve patients (six with primary lesions and six with recurrent tumors) underwent laryngectomy, and the macro- and microscopic appearance of the slice specimens...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198701000-00027
更新日期:1987-01-01 00:00:00
abstract::Repeat examinations in a de novo patient with Wilson disease revealed an expansion of decreased signal intensities in the basal ganglia on T2-weighted imaging after initiation of copper trapping therapy. Since marked clinical improvement was associated with continued urinary copper excretion, iron depositioning in exc...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199507000-00026
更新日期:1995-07-01 00:00:00
abstract::The authors report three cases of abnormal chest radiography mimicking mediastinal masses. These radiographic findings were unrelated to any pathology, were discovered in asymptomatic patients, and must be considered consequences of unusually narrow thoracic inlets. Mean and standard deviations of the anteroposterior ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198607000-00011
更新日期:1986-07-01 00:00:00
abstract::The magnetic resonance appearance of three lesions of focal nodular hyperplasia observed in two patients is reviewed. All three lesions demonstrated isointensity with the liver on the short repetition time (TR) and echo time (TE) spin echo images. One lesion also showed a central area of low signal intensity that path...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198707000-00019
更新日期:1987-07-01 00:00:00
abstract:PURPOSE:To evaluate the usefulness of CT in the differentiation of ruptured endometrial cysts and corpus luteal cysts. METHODS:Sixteen patients (mean age, 26 years) with a surgically proven ruptured endometrial cyst and 19 patients (mean age, 28 years) with a surgically proven corpus luteal cyst were included in this ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e31821f4bd2
更新日期:2011-07-01 00:00:00
abstract::We report a case of benign hemangioendothelioma of infancy extending from the deep soft tissues of the neck to involve the entire longitudinal extent of the right posterior mediastinum. The CT findings that aid in the differential diagnosis of this and other posterior mediastinal masses are discussed. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198609000-00033
更新日期:1986-09-01 00:00:00
abstract::A 72-year-old woman with previously symptomatic internal carotid artery occlusion subsequently presented with an acute hemispheric deficit. The patient was initially diagnosed as having an ischemic infarction but eventually was shown to have a subacute subdural hematoma with delay in surgical evacuation and a major pe...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198909000-00029
更新日期:1989-09-01 00:00:00
abstract::Congenital alimentary duplications occur most commonly in relation to the ileum and are rare in the region of the stomach. A case of gastric duplication presenting in an adult and visualized on computed tomography is reported. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198304000-00025
更新日期:1983-04-01 00:00:00
abstract::We studied four patients with adrenocorticotropic hormone (ACTH)-independent hypercortisolism due to bilateral massive enlargement of the adrenal glands. The combined weight of the adrenal glands ranged from 69 to 149 g and the adrenal cortex was replaced in three of four patients by multiple nodules ranging from micr...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章,评审
doi:10.1097/00004728-199109000-00009
更新日期:1991-09-01 00:00:00
abstract:OBJECTIVE:The objective was to elucidate clinical effectiveness of submillimeter multislice 2- and 3-dimensional computed tomography (CT) for diagnosis of congenital middle ear anomaly. MATERIALS AND METHODS:Preoperative CT and operative findings were retrospectively analyzed in 36 ears of 33 patients. The distance be...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0000000000000093
更新日期:2014-09-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to assess the feasibility of performing diagnostic-quality contrast-enhanced excretory magnetic resonance urography (eMRU) at 3T, examining both image quality and diagnostic accuracy for a range of urinary tract abnormalities. METHODS:The diuretic-enhanced 3T eMRUs of 37 patie...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e3182711fd9
更新日期:2013-01-01 00:00:00
abstract::Construction of a new ultrafast scanner system suitable for dynamic computed tomography is now under consideration, with development soon to begin. This system will be characterized by an electronically controlled X-ray generator with wide angle double diffraction, which will permit transverse axial images to be taken...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-197710000-00017
更新日期:1977-10-01 00:00:00
abstract:PURPOSE:The aim of this study was to evaluate the diagnostic accuracy and complication rates of a side-exiting coaxial needle system for fine needle aspiration (FNA) biopsies. METHOD:Between 1995 and 1998, 127 nonconsecutive biopsies were performed on 122 patients (74 males, 48 females). CT guidance was used in 111, u...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-200203000-00023
更新日期:2002-03-01 00:00:00
abstract::Four patients (three with hepatocellular carcinoma and one with colorectal carcinoma metastatic to the liver) previously treated with chemotherapy or radiotherapy or both in an attempt to reduce tumor bulk prior to surgical resection were examined by CT angiography (CTA). Areas of abnormal enhancement and irregular ve...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198807000-00007
更新日期:1988-07-01 00:00:00
abstract:OBJECTIVE:The dimensions of the optic nerves, chiasm, and tracts were determined in normal patients and in patients with clinical evidence of optic atrophy to establish whether there was a significant difference between the two groups. MATERIALS AND METHODS:The authors analyzed thin section coronal MRI of 110 patients...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199309000-00003
更新日期:1993-09-01 00:00:00
abstract::A 3% barium paste was used in the CT evaluation of 100 normal and 60 abnormal esophagi. Successful esophageal opacification occurred in 87% of both groups. In cases of extrinsic disease involving the esophagus the contrast medium administration assisted in separating the esophagus from adjacent mass lesions, as well a...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198803000-00004
更新日期:1988-03-01 00:00:00
abstract:BACKGROUND:Neonatal hypoxic-ischemic encephalopathy (HIE) is associated with dysfunctional cerebral autoregulation. Resistive index (RI) measured in the anterior cerebral artery on transfontanellar head ultrasound is a noninvasive measure of blood flow and may indicate autoregulation dysfunction. We tested whether RI w...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0000000000001069
更新日期:2020-09-01 00:00:00
abstract::Neutrons and X-rays are mathematically equivalent as probes in computed tomography. However, structure in the energy dependence of neutron total cross sections and the feasibility of using time-of-flight techniques for energy sensitivity in neutron detection suggest that spatial distributions of specific substances ca...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198302000-00021
更新日期:1983-02-01 00:00:00
abstract::Seven patients with supratentorial infarction were studied by means of serial nuclear magnetic resonance imaging using saturation recovery (SR) and proton density (PD) sequences. The earliest changes were visible in the more sensitive T1 dependent images (SR) and may reflect the cytotoxic component of ischemic brain e...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:
更新日期:1983-08-01 00:00:00
abstract:PURPOSE:The purpose of our study was to test dynamic helical CT (hCT) in the evaluation of breast tumors. METHOD:Thirty-six patients with 39 suspected lesions underwent breast hCT before and 1, 3, and 8 min after intravenous contrast medium administration. A marked enhancement (> or = 100%) at 1 or 3 min without incre...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199805000-00010
更新日期:1998-05-01 00:00:00
abstract::A lipoma eroding the scapula is diagnosed by computed tomography. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-197910000-00018
更新日期:1979-10-01 00:00:00
abstract::We report a rare case of a bronchogenic cyst presenting as a pleural nodule. CT and MRI demonstrated a well circumscribed, homogeneous lesion located on the pleural surface apart from the mediastinum. It was proven to be a bronchogenic cyst localized between the parietal and visceral pleurae and connected with the med...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-200007000-00012
更新日期:2000-07-01 00:00:00
abstract:OBJECTIVE:Our goal was to analyze the sources of nonuniform image intensity of two surface coil configurations used on a General Electric 1.5 T Signa scanner and to correct the major source. MATERIALS AND METHODS:Correction of receive coil nonuniform sensitivity is achieved using division by images of a uniform phanto...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199411000-00033
更新日期:1994-11-01 00:00:00
abstract::Twenty-five patients with surgically and histologically proven squamous cell carcinoma of the palatine tonsil were studied with computed tomography (CT) using a high dose intravenous contrast enhancement technique. With this technique, CT demonstrated the primary carcinoma within the palatine fossa as well as its cont...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198312000-00007
更新日期:1983-12-01 00:00:00
abstract:OBJECTIVE:Our retrospective study was performed to reassess the common dynamic CT manifestations of cystic tumors of the pancreas and to determine whether they might allow the differentiation between benign and malignant tumors. MATERIALS AND METHODS:Dynamic CT examinations of 19 patients with 20 cystic tumors of the ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199405000-00015
更新日期:1994-05-01 00:00:00
abstract::This report describes the imaging findings of the first reported case of a bronchobiliary fistula that developed as a complication of liver transplantation. The diagnosis was confirmed by the aspiration of bile from the bronchus. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/01.rct.0000131583.52386.cf
更新日期:2004-09-01 00:00:00
abstract::Maple syrup urine disease (MSUD) is an inherited metabolic disorder due to decreased decarboxylation of branched chain keto acids triggering an accumulation of leucine, isoleucine, and valine. We describe two infants with biochemically confirmed MSUD in whom computed tomography (CT) revealed cerebral edema. In one of ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198406000-00007
更新日期:1984-06-01 00:00:00
abstract::Ovarian fibromatosis is a rare benign nonneoplastic condition with ovarian enlargement in young women and characterized by a proliferation of collagen-producing spindle cells surrounding normal ovarian structures. We reported magnetic resonance findings of a case that the affected ovarian parenchyma with follicles was...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e318157689a
更新日期:2008-09-01 00:00:00
abstract:PURPOSE:A new nonrigid registration method, designed to reduce the effect of movement artifact in subtraction images from breast MR, is compared with existing rigid and affine registration methods. METHOD:Nonrigid registration was compared with rigid and affine registration methods and unregistered images using 54 gad...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199909000-00031
更新日期:1999-09-01 00:00:00
abstract::A case of simultaneous renal vein thrombosis and bilateral adrenal hemorrhage is presented, demonstrating the ability of magnetic resonance (MR) imaging to identify these abnormalities without the use of intravenous contrast agents or radiopharmaceuticals. Adrenal hemorrhage appeared as markedly enlarged adrenal gland...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198607000-00028
更新日期:1986-07-01 00:00:00