Benign or malignant?: differentiating breast lesions with computed tomography attenuation values on dynamic computed tomography mammography.

Abstract:

OBJECTIVE:To evaluate enhancement effects of breast lesions with dynamic computed tomography (CT) and to determine characteristics to aid in differential diagnosis of benign and malignant lesions. METHODS:One hundred seventy-six women underwent preoperative dynamic CT, in which they were scanned with rapid injection of contrast media (3 mL/s) after 30 seconds and 2 minutes (early and delayed phases, respectively). The CT values and enhancement patterns of malignant lesions (n = 154) were compared with those of benign lesions (n = 22), and the cut point of CT values with the best validity was analyzed. RESULTS:The CT values of malignant lesions were higher than those of benign lesions in both phases (P < 0.0001). The cut point was determined to be 60 Hounsfield units (HU) in the early phase (44% validity, 90% sensitivity). Washout and plateau patterns were more commonly seen in the malignant group (73% specificity). CONCLUSIONS:The analysis of enhancement effects on CT may lead to more appropriate differentiation of benign and malignant lesions.

journal_name

J Comput Assist Tomogr

authors

Miyake K,Hayakawa K,Nishino M,Nakamura Y,Morimoto T,Urata Y,Ueda H,Tanikake M,Kanao S,Shiozaki T,Yamamoto A

doi

10.1097/01.rct.0000178712.32547.53

keywords:

subject

Has Abstract

pub_date

2005-11-01 00:00:00

pages

772-9

issue

6

eissn

0363-8715

issn

1532-3145

pii

00004728-200511000-00012

journal_volume

29

pub_type

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