Benign melanocytic tumor in infancy: discussion on a rare case and review of the literature.

Abstract:

:Meningeal melanocytoma is an infrequent neoplasm of the central nervous system (CNS), especially in childhood and infancy. It was first described as an entity different from pigmented meningiomas and schwannomas in 1972, and few cases have been published so far. In this article, a 5-month-old male patient with meningeal melanocytoma is presented. This midline lesion was localized in the posterior fossa and manifested by hydrocephalus. The entire dural origin and extradural growing pattern in addition to the destruction of the adjacent occipital bone were the unexpected presentations since these tumors usually tend to locate on leptomeninges and to extend into the adjacent neural compartment rather than the outside. On the other hand, this case is the only one which had identical lesions in both surrenal glands and the left renal capsule, the structures containing neural-crest-derived cells outside the CNS. The prognostic criteria, differential diagnosis and its embryological aspects are discussed with an extensive review of the related existing literature.

journal_name

Pediatr Neurosurg

journal_title

Pediatric neurosurgery

authors

Oruckaptan HH,Soylemezoglu F,Kutluk T,Akalan N

doi

10.1159/000028945

keywords:

subject

Has Abstract

pub_date

2000-05-01 00:00:00

pages

240-7

issue

5

eissn

1016-2291

issn

1423-0305

pii

28945

journal_volume

32

pub_type

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