Abstract:
:Muscle injury triggers a sequence of events that begin with a host inflammatory response that is followed by muscle fiber regeneration and new collagen synthesis. The inflammatory response involves at least three types of cells, including neutrophils, ED1+ macrophages, and ED2+ macrophages. A host of growth factors and cytokines appear to play a role in the inflammatory process and repair of the damaged tissue. Satellite cells play an integral role in normal development of skeletal muscle by providing a source for postmitotic myonuclei. In addition, the satellite cell is essential to the repair of injured muscle by serving as a source of myoblasts for fiber regeneration. At the same time muscle fiber regeneration is occurring, there is expression of types I and III collagen that under certain circumstances can lead to scarring and fibrosis. Current studies of treatment of muscle injury often incorporate investigations of basic principles of injury and repair together with clinical experience and principles in an effort to coordinate basic science and outcome studies.
journal_name
Phys Med Rehabil Clin N Amauthors
Best TM,Hunter KDkeywords:
subject
Has Abstractpub_date
2000-05-01 00:00:00pages
251-66issue
2eissn
1047-9651issn
1558-1381journal_volume
11pub_type
杂志文章,评审abstract::Evidence supporting the use of specific physical agents in the management of chronic pain conditions is not definitive; it is largely incomplete and sometimes contradictory. However, the use of agents in chronic pain management programs is common. Within the broad use of physical agents, they are rarely the sole modal...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pmr.2005.12.007
更新日期:2006-05-01 00:00:00
abstract::This article reviews and summarizes the literature on patient safety issues in the rehabilitation of adults with an amputation. Safety issues in the following areas are discussed; the prosthesis, falls, wound care, pain, and treatment of complex patients. Specific recommendations for further research and implementatio...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pmr.2012.02.011
更新日期:2012-05-01 00:00:00
abstract::Following the lead of Washington state and passage of the Lystedt Law in 2009, all states now have sports concussion laws designed to help protect youth athletes. This article examines the 3 basic tenets of youth sports concussion laws, challenges in implementation of state laws, and the first measures of success. Som...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pmr.2015.12.006
更新日期:2016-05-01 00:00:00
abstract::The relevance of cancer rehabilitation as a public health issue grows steadily as cancer incidence, survival, and mean patient age increase. Reported rates of physical impairment and disability are already high, prior to the anticipated influx of aged cancer survivors. Despite the high prevalence of cancer-related dis...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pmr.2016.08.001
更新日期:2017-02-01 00:00:00
abstract::Most knee structures can be accurately targeted using ultrasound guidance. These structures are usually superficial, and the overlying soft tissues are mobile and compressible, facilitating excellent visualization with a high-frequency linear array transducer. The circumferential accessibility to the knee affords flex...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pmr.2016.04.010
更新日期:2016-08-01 00:00:00
abstract::There are special aspects of aging with an amputation and with being elderly at the time of an amputation. Older adults who have undergone amputation have many issues to contend with, including comorbidities that affect postoperative care and rehabilitation, general deconditioning and loss of mobility (especially if t...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pmr.2004.06.004
更新日期:2005-02-01 00:00:00
abstract::Neck pain should not, and must not, be confused with cervical radicular pain. Equating the two conditions, or confusing them, results in misdiagnosis, inappropriate investigations, and inappropriate treatment that is destined to fail. So critical is the difference that pedagogically it is unwise to include the two top...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pmr.2011.03.008
更新日期:2011-08-01 00:00:00
abstract::Chronic pain associated with traumatic spinal cord injury (SCI) can be quite challenging to the physiatrist. This highly prevalent condition within the SCI population requires an appropriate evaluative approach including a thorough history, a targeted physical examination, and appropriate use of diagnostic testing. Th...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pmr.2014.01.002
更新日期:2014-05-01 00:00:00
abstract::Neuromuscular disorders associated with monoclonal gammopathies are usually uncovered in approximately 10% of patients presenting with peripheral neuropathy complaints. This discovery should prompt further evaluation for underlying plasma cell dyscrasias. The most frequent monoclonal disorders associated with neuropat...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pmr.2007.10.005
更新日期:2008-02-01 00:00:00
abstract::It is beneficial for both worker and employer for the worker to return to work (RTW) as early as possible after an illness, injury, or prolonged absence. Because employers are ultimately responsible for the RTW decision, a medical RTW assessment is commonly required to assure that the worker is medically able to and p...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章
doi:10.1016/j.pmr.2019.04.002
更新日期:2019-08-01 00:00:00
abstract::Tone management is one of the primary roles of a pediatric physiatrist. Hypertonicity frequently inhibits normal movement patterns in children with central nervous system lesions but at times can reinforce muscle group firing and be useful for a child's function. Treatment approaches should be individualized based on ...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pmr.2014.09.008
更新日期:2015-02-01 00:00:00
abstract::Chronic pelvic pain can result from various intra- and extra-pelvic etiologies. Although patient history and physical examination may narrow the differential diagnosis, frequently, the different etiologies have overlapping presentations. Imaging examinations such as US and/or MR imaging may help delineate the cause of...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pmr.2017.03.004
更新日期:2017-08-01 00:00:00
abstract::Antidepressant medications have a variety of uses in addition to the treatment of depression. This article focuses on the two most widely used categories of antidepressants, tricyclic antidepressants (TCAs) and the newer selective serotonin reuptake inhibitors (SSRIs), and highlights their use in post-stroke depressio...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1999-05-01 00:00:00
abstract::Rehabilitation and regenerative medicine therapies has shown improved outcomes for tissue regeneration. Regenerative rehabilitation guides protocols regarding when to start therapy, types of stimuli administered, and graded exercise programs, taking into account biological factors and technologies designed to optimize...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pmr.2016.07.002
更新日期:2016-11-01 00:00:00
abstract::Care and treatment of female runners will improve as further knowledge regarding the unique factors that affect them becomes available. For care and treatment to be their most effective, current and recent information needs to be disseminated among health care providers, coaches, teachers, school administrators, and p...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pmr.2005.03.002
更新日期:2005-08-01 00:00:00
abstract::Expert opinion on life expectancy must make reasonable factual assumptions, which entails finding a proper group to which the individual being assessed will be compared, as well as use of appropriate and reliable technical methods. Reasonable judgment should be exercised in the selection of the studies employed. A sch...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pmr.2013.03.007
更新日期:2013-08-01 00:00:00
abstract::The prosthetic socket must act as a customized connection between the residual limb's surrounding tissues and the prosthetic components. The socket must be designed to control weight bearing, suspension, and ambulation stability. When making a below-the-knee socket, the prosthetist attempts to maximize loading and min...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:2000-08-01 00:00:00
abstract::Although most patients recover from acute whiplash injuries, those with chronic whiplash syndrome develop signs of central nervous system (CNS) amplification of pain and have a poor prognosis. In this context, specific pain generators from acute whiplash have been identified through clinical, biomechanical, and animal...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pmr.2015.01.003
更新日期:2015-05-01 00:00:00
abstract::The concepts associated with work disability are not identical to those associated with medical disability. In addition to a worker's medical condition, the resultant functional limitations, and loss of participation in society, the injured or ill worker must often navigate a complex administrative system that often s...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章
doi:10.1016/j.pmr.2019.03.012
更新日期:2019-08-01 00:00:00
abstract::Although Para athletes (the International Paralympic Committee term for sportspeople with a disability) are exposed to a risk of concussion just like their able-bodied counterparts, there has been little research into the incidence of concussion in para sport. Existing assessment and management guidelines and tools ha...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pmr.2018.01.002
更新日期:2018-05-01 00:00:00
abstract::This article has briefly highlighted the area of sport psychology as it relates to performance psychology skills (mental training), including a historical overview and current topics overview. The use of mental training skills may be of interest to the practicing physical medicine and rehabilitation professional in th...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 历史文章,杂志文章,评审
doi:10.1016/j.pmr.2006.05.007
更新日期:2006-08-01 00:00:00
abstract::As more people survive burn injuries, there is an increasing focus on managing the complications of burn injuries with the ultimate goal of improving survivors' quality of life. Musculoskeletal and neurologic sequelae are significant complications of burn injury. Electrical injury is a subcategory of burns with multip...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pmr.2011.01.003
更新日期:2011-05-01 00:00:00
abstract::EBP is not a new concept. To practice using the newest and best research evidence, clinicians must have the knowledge and skills to find and appraise the quality of the evidence. This process starts with the formulation of a focused question, followed by an effective search for the best evidence, critical appraisal of...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s1047-9651(02)00027-x
更新日期:2002-11-01 00:00:00
abstract::These cases represent individuals who feel they have a severe impairment and are "disabled." They have been labeled with fibromyalgia. They are truly distressed. Their symptoms, their courses, are more chronic and refractory than those of medically ill patients, and they are high users of medical services, laboratory ...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章
doi:
更新日期:2001-08-01 00:00:00
abstract::This article explores a variety of myths and facts about therapy for children who have cerebral palsy. Current evidence is used to refute popular myths and debunk harmful ones. A way of integrating interventions is suggested and a planning process for timing interventions is proposed. ...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章
doi:10.1016/s1047-9651(02)00025-6
更新日期:2002-11-01 00:00:00
abstract::The advent of equipment capable of performing SEPs, MEPs, and EMG in a multiplexed manner and in a timely fashion brings a new level of monitoring that far exceeds the previous basic monitoring done with SEPs only. Whether this more comprehensive monitoring will result in greater protection of the nervous system await...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s1047-9651(03)00106-2
更新日期:2004-02-01 00:00:00
abstract::Elderly people have several characteristics that make them unique. They have several factors such as environmental factors and demographic factors such as age, sex, socioeconomic level, and schooling, which contribute to these differences being accentuated. As one ages, these various organic and systemic features are ...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pmr.2017.06.007
更新日期:2017-11-01 00:00:00
abstract::Disease-modifying agents that decrease the accumulation of disability are costly, inconvenient to use, and have the potential of significant side effects. The findings presented here suggest that much less costly health-promotion interventions may hold substantial promise as a complementary strategy for decreasing the...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:2001-02-01 00:00:00
abstract::Clinical and electrical myotonia is caused by a small group of neuromuscular disorders. This article reviews myotonia and its differential diagnosis. The use of electrodiagnostic testing to evaluate the primary myotonic disorders (myotonic dystrophy and the nondystrophic myotonias) is also discussed. ...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pmr.2012.08.015
更新日期:2013-02-01 00:00:00
abstract::Physiatrists are a valuable resource in legal settings, where assessment of functional capacity to perform work and of future medical needs must be determined. Physiatrists help determine what future medical care is needed to restore and maintain an individual at the maximum level of life function. This article focuse...
journal_title:Physical medicine and rehabilitation clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s1047-9651(01)00004-3
更新日期:2002-05-01 00:00:00