Abstract：
:Sera were collected from a total of 122 children, comprising 117 cases with undifferentiated fever and 5 cases with dengue hemorrhagic fever (DHF), during June to September 1994 in Karachi, Pakistan. Sera were tested by the IgM-capture ELISA using dengue type 1 (D1), dengue type 2 (D2), West Nile (WN), and Japanese encephalitis (JE) viral antigens. Among 92 single sera from undifferentiated fever cases, IgM antibodies were detected in 5 cases by D1, 8 cases by D2, and 5 cases by WN antigens, respectively. Corresponding number of positives among 25 paired sera from undifferentiated fever cases were 3 by D1, 6 by D2, and 1 by WN antigen. Four out of 5 DHF cases possessed anti-D1 as well as anti-D2 IgM antibodies. Only a single DHF case was positive for anti-WN IgM antibodies. Anti-JE IgM antibodies were not detected in any of the tested serum specimens. Clinical manifestations of undifferentiated fever patients were generally non specific, but the percentage of children with anemia, hepatomegaly and splenomegaly was higher in patients possessing anti-dengue IgM antibodies than those without. Among the groups with anti-dengue IgM antibodies, those possessing only anti-D2 but not anti-D1 IgM antibodies showed higher percentages with cough, edema, and splenomegaly. The results indicated that up to 26% of the undifferentiated fever cases were caused by dengue virus infection in Karachi, Pakistan.
journal_name
Indian J Pediatrjournal_title
Indian journal of pediatricsauthors
Akram DS,Igarashi A,Takasu Tdoi
10.1007/BF02731055keywords:
subject
Has Abstractpub_date
1998-09-01 00:00:00pages
735-40issue
5eissn
0019-5456issn
0973-7693journal_volume
65pub_type
杂志文章abstract：OBJECTIVE:The present study aimed to estimate the prevalence of acute diarrhea and its correlates in remote rural villages of south Pakistan. METHODS:The authors selected 1878 children less than 3 years of age through stratified random sampling from 64 villages having the number of children enrolled proportionate to t...
journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02725583
更新日期：2003-03-01 00:00:00
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journal_title：Indian journal of pediatrics
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abstract：OBJECTIVE:To investigate obesogenic co-causing factors, promoting rise of weight in children, associated to local differences in India. METHODS:Overall 1,680 children, aged 3-11 and balanced by gender, were recruited in school contexts distributed in seven major Indian cities. All children were weighted and measured i...
journal_title：Indian journal of pediatrics
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abstract：:Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disorder characterized by ectopic bone formation involving the connective tissues leading to severe skeletal manifestations. The genetic defect in this disorder has not been characterized in Indian patients till date. The authors report three cases of FOP a...
journal_title：Indian journal of pediatrics
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journal_title：Indian journal of pediatrics
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abstract：OBJECTIVES:To review the literature for justification of thoracoscopic management of blebs in children. METHODS:PubMed database was reviewed for articles in English, Portuguese and Spanish using the key words "thoracoscopy", "bleb" and "child". Data was collected for age, gender, type of surgery performed, operating t...
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journal_title：Indian journal of pediatrics
pub_type： 杂志文章,评审
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更新日期：2008-08-01 00:00:00
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更新日期：1990-01-01 00:00:00
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更新日期：2014-01-01 00:00:00
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更新日期：2009-05-01 00:00:00
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更新日期：1994-03-01 00:00:00
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更新日期：2006-10-01 00:00:00
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pub_type： 信件
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pub_type： 杂志文章,评审
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更新日期：1999-01-01 00:00:00
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更新日期：2011-08-01 00:00:00
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更新日期：1998-11-01 00:00:00
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更新日期：1989-01-01 00:00:00
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更新日期：2020-08-01 00:00:00
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journal_title：Indian journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s12098-017-2436-8
更新日期：2018-01-01 00:00:00
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journal_title：Indian journal of pediatrics
pub_type： 杂志文章,评审
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更新日期：2016-07-01 00:00:00
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journal_title：Indian journal of pediatrics
pub_type： 杂志文章
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更新日期：2004-12-01 00:00:00
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更新日期：2020-11-01 00:00:00
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journal_title：Indian journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02727152
更新日期：1999-07-01 00:00:00
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pub_type： 杂志文章,随机对照试验
doi：10.1007/s12098-012-0839-0
更新日期：2013-07-01 00:00:00
