MRI findings in Hirayama's disease: flexion-induced cervical myelopathy or intrinsic motor neuron disease?

abstract：BACKGROUND:Contactin-associated protein-like 2 (CASPR2) autoantibody disease has a variable clinical phenotype. We present a case report and performed a systematic review of the literature to summarize: (1) the clinical phenotype of patients with CASPR2 antibodies, (2) the findings in neurological investigations, and (...

journal_title：Journal of neurology

authors： Boyko M,Au KLK,Casault C,de Robles P,Pfeffer G

更新日期：2020-04-01 00:00:00

abstract：:Both neurologists and urologists might encounter patients with acute urinary retention due to benign inflammatory nervous diseases. Based on the mechanism of urinary retention, these disorders can be divided into two subgroups: disorders of the peripheral nervous system (e.g., sacral herpes) or the central nervous sys...

journal_title：Journal of neurology

authors： Sakakibara R,Yamanishi T,Uchiyama T,Hattori T

更新日期：2006-08-01 00:00:00

abstract：:We describe three patients with unilateral asterixis. One diabetic patient with a moderately-sized haematoma in the left putamen initially developed bilateral and symmetrical asterixis, which became confined to the right side as his diabetes mellitus was controlled. Two patients showed unilateral asterixis due to haem...

journal_title：Journal of neurology

authors： Mizutani T,Shiozawa R,Nozawa T,Nozawa Y

更新日期：1990-12-01 00:00:00

abstract：:The highest risk of subsequent stroke after a TIA occurs within the first week after the index event. However, the risk of stroke recurrence (SR) remains high during the first year of follow-up. We studied the temporal pattern and predictors of SR (at 7 days and from 7 days to 1-year follow-up). Between April 2008 and...

journal_title：Journal of neurology

authors： Purroy F,Jiménez Caballero PE,Gorospe A,Torres MJ,Alvarez-Sabin J,Martínez-Sánchez P,Cánovas D,Freijo M,Egido JA,Ramírez-Moreno JM,Alonso-Arias A,Rodríguez-Campello A,Casado-Naranjo I,Martí-Fàbregas J,Silva Y,Cardona P,Mo

更新日期：2014-08-01 00:00:00

abstract：:Vitamin B(12) (VitB(12), cobalamin) deficiency has been associated with various neuropsychiatric conditions, such as peripheral neuropathy, subacute combined degeneration, affective disorders, and cognitive impairment. Current assays analyze vitamin B(12), of which only a small percentage is metabolically active. Meas...

journal_title：Journal of neurology

authors： Schrempf W,Eulitz M,Neumeister V,Siegert G,Koch R,Reichmann H,Storch A

更新日期：2011-03-01 00:00:00

abstract：:Fabry disease (FD) is a rare inherited disorder of the metabolism, associated with renal, cardiac, and cerebrovascular complications. Ischemic and hemorrhagic stroke in FD present with a similar proportion to that observed in the general population, but usually at an early age. Ischemic stroke may result from cardiac ...

journal_title：Journal of neurology

authors： Viana-Baptista M

更新日期：2012-06-01 00:00:00

abstract：:The pathogenesis of myopathies occurring in critically ill patients (critical illness myopathy, CIM) is poorly understood. Both local and systemic responses to sepsis and other severe insults to the body are presumed to be involved but the precise mechanisms by which muscle function is impaired are far from clear. To ...

journal_title：Journal of neurology

authors： Friedrich O,Hund E,Weber C,Hacke W,Fink RH

更新日期：2004-01-01 00:00:00

abstract：:The neurochemical abnormalities underlying vascular parkinsonism (VP) have not been well characterised. A better understanding may help to optimize pharmacological interventions. Since VP patients generally have a poorer response to l-Dopa than Parkinson's disease (PD) patients, we investigated whether levels of relev...

journal_title：Journal of neurology

authors： Herbert MK,Kuiperij H,Bloem BR,Verbeek MM

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVES:To evaluate daily life management and functional outcome of Idarucizumab administration in case of emergency situations in patients with Dabigatran treatment. DESIGN:Multicenter observational registry study. SETTING:All hospitals with full neurological departments (n = 6) in Munich, Germany INCLUDED PATIEN...

journal_title：Journal of neurology

authors： Küpper C,Feil K,Klein M,Feuerecker R,Lücking M,Thanbichler F,Dietrich D,Zerkaulen I,Jandl M,Marziniak M,Poppert H,Wunderlich S,Topka H,Dieterich M,Kellert L

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Body weight reduction after disease onset is an independent predictor of survival in amyotrophic lateral sclerosis (ALS), but significance of weight variation after diagnosis remains to be established. OBJECTIVE:To investigate weight variation after diagnosis and its prognostic significance in patients with...

journal_title：Journal of neurology

authors： Shimizu T,Nakayama Y,Matsuda C,Haraguchi M,Bokuda K,Ishikawa-Takata K,Kawata A,Isozaki E

更新日期：2019-06-01 00:00:00

abstract：:Erdheim-Chester disease (ECD) is a rare, non-Langerhans form of histiocytosis of unknown etiology that affects multiple organs. We report 6 cases of ECD with neurological involvement and neuroradiological abnormalities on brain MRI. A literature review revealed 60 other cases of ECD with neurological involvement. We t...

journal_title：Journal of neurology

authors： Lachenal F,Cotton F,Desmurs-Clavel H,Haroche J,Taillia H,Magy N,Hamidou M,Salvatierra J,Piette JC,Vital-Durand D,Rousset H

更新日期：2006-10-01 00:00:00

abstract：INTRODUCTION:Ataxic polyneuropathy, which occurs in endemic form in an area in southwest Nigeria, is attributed to exposure to cyanide from cassava foods. Exposure to cyanide from cassava is, however, not exclusive to this endemic area. In this study, the occurrence of ataxic polyneuropathy was compared in two communit...

journal_title：Journal of neurology

authors： Oluwole OS,Onabolu AO,Cotgreave IA,Rosling H,Persson A,Link H

更新日期：2002-08-01 00:00:00

abstract：OBJECTIVE:A growing number of studies have been conducted on the relationship between anger and hostility and the risk of stroke, and their conclusions are not consistent. Accordingly, we performed a meta-analysis to evaluate the relationship between anger and hostility and the risk of stroke. METHODS:We searched the ...

journal_title：Journal of neurology

authors： Chen H,Zhang B,Xue W,Li J,Li Y,Fu K,Chen X,Sun M,Shi H,Tian L,Teng W

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:An upper motor neuron (UMN) lesion in amyotrophic lateral sclerosis (ALS) is often difficult to identify because clinical signs may be discrete or masked by severe simultaneous LMN lesions. We compared the diagnostic sensitivity of transcranial magnetic stimulation (TMS) to cranial muscles and limb muscles i...

journal_title：Journal of neurology

authors： Urban PP,Wicht S,Hopf HC

更新日期：2001-10-01 00:00:00

abstract：:The production and release of extracellular vesicles (EV) is a property shared by all eukaryotic cells and a phenomenon frequently exacerbated in pathological conditions. The protein cargo of EV, their cell type signature and availability in bodily fluids make them particularly appealing as biomarkers. We recently dem...

journal_title：Journal of neurology

authors： Denis HL,Lamontagne-Proulx J,St-Amour I,Mason SL,Weiss A,Chouinard S,Barker RA,Boilard E,Cicchetti F

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVE:Neuropsychological impairments are major symptoms of autoimmune limbic encephalitis (LE) epilepsy patients. In LE epilepsy patients with an autoimmune response against intracellular antigens as well as in antibody-negative patients, the antibody findings and magnetic resonance imaging pathology correspond poo...

journal_title：Journal of neurology

authors： Helmstaedter C,Hansen N,Leelaarporn P,Schwing K,Oender D,Widman G,Racz A,Surges R,Becker A,Witt JA

更新日期：2020-08-20 00:00:00

abstract：UNLABELLED:The objective of this study was to investigate the relationship between electrophysiological recordings and clinical as well as radiological findings in patients suggestive to suffer from a lumbar spinal stenosis (LSS). We hypothesise that the electrophysiological recordings, especially SSEP, indicate a lumb...

journal_title：Journal of neurology

authors： Egli D,Hausmann O,Schmid M,Boos N,Dietz V,Curt A

更新日期：2007-06-01 00:00:00

abstract：OBJECTIVE:Patients with classic ataxia-telangiectasia (A-T) generally die in the second or third decade of life. Clinical descriptions of A-T tend to focus on the symptoms at presentation. However, during the course of the disease, other symptoms and complications emerge. As long-term survivors with classic A-T develop...

journal_title：Journal of neurology

authors： van Os NJH,van Deuren M,Weemaes CMR,van Gaalen J,Hijdra H,Taylor AMR,van de Warrenburg BPC,Willemsen MAAP

更新日期：2020-03-01 00:00:00

abstract：:The United Nations High Commissioner for Refugees (UNHCR) recognizes 43.7 million forcibly displaced persons and asylum seekers due to conflict and persecution worldwide. Neurological disorders have rarely been described in displaced persons but likely pose a significant burden of disease. We describe the disease spec...

journal_title：Journal of neurology

authors： Mateen FJ,Carone M,Nyce S,Ghosn J,Mutuerandu T,Al-Saedy H,Lowenstein DH,Burnham G

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that still lacks reliable diagnostic biomarkers. This study aims to evaluate the diagnostic and prognostic potential of CSF total Tau (t-Tau), phospho-Tau (p-Tau) and p-Tau/t-Tau ratio in ALS patients using CSF neurofilament light (NFL)...

journal_title：Journal of neurology

authors： Scarafino A,D'Errico E,Introna A,Fraddosio A,Distaso E,Tempesta I,Morea A,Mastronardi A,Leante R,Ruggieri M,Mastrapasqua M,Simone IL

更新日期：2018-10-01 00:00:00

abstract：INTRODUCTION:The spinocerebellar ataxias (SCAs), are rare neurodegenerative disorders caused by distinct genetic mutations. Clinically, the SCAs are characterised by progressive ataxia and a variety of other features, including cognitive dysfunction. The latter is consistent with a growing body of evidence supporting a...

journal_title：Journal of neurology

authors： Garrard P,Martin NH,Giunti P,Cipolotti L

更新日期：2008-03-01 00:00:00

abstract：:We analysed the CACNA1A gene, located on chromosome 19p13, in three unrelated families and one sporadic case with episodic ataxia type 2 (EA-2). In two of the families and the sporadic patient, novel truncating mutations, which disrupt the reading frame and result in a premature stop of the CACNA1A protein, were ident...

journal_title：Journal of neurology

authors： van den Maagdenberg AM,Kors EE,Brunt ER,van Paesschen W,Pascual J,Ravine D,Keeling S,Vanmolkot KR,Vermeulen FL,Terwindt GM,Haan J,Frants RR,Ferrari MD

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:Epilepsy in children negatively impacts on caregiver quality of life (QOL). The study aimed to evaluate the relationships between patient factors [demographics, clinical factors, health-related quality of life (HRQL)], contextual factors (socio-economic factors), caregiver mood, and caregiver QOL, and whethe...

journal_title：Journal of neurology

authors： Jain P,Subendran J,Smith ML,Widjaja E,PEPSQOL Study Team.

更新日期：2018-10-01 00:00:00

abstract：:In this study of patients with spontaneous cervical artery dissections (sCAD) we searched for mutations in ABCC6, the candidate gene for Pseudoxanthoma elasticum (PXE). Genomic DNA samples from 12 sCAD patients with pronounced electron microscopic alterations in their dermal connective tissue and from 2 patients with ...

journal_title：Journal of neurology

authors： Morcher M,Hausser I,Brandt T,Grond-Ginsbach C

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:Elective programs for medical students in the last year of their university training are poorly evaluated. The goal of this study was to determine the gain in theoretical and practical skills in a group of students during their elective in neurology. Students were trained by either conventional teaching meth...

journal_title：Journal of neurology

authors： Heckmann JG,Bleh C,Dütsch M,Lang CJ,Neundörfer B

更新日期：2003-12-01 00:00:00

abstract：:The geste antagoniste is a voluntary maneuver that temporarily reduces the severity of dystonic posture or movements. It is a classical feature of focal and particularly cervical dystonia. However, the precise historical aspects of geste antagoniste still remain obscure. The goals of this review were (1) to clarify th...

journal_title：Journal of neurology

authors： Poisson A,Krack P,Thobois S,Loiraud C,Serra G,Vial C,Broussolle E

更新日期：2012-08-01 00:00:00

abstract：:The objective of this study was to assess the effect of secukinumab, a monoclonal antibody that inhibits interleukin (IL)-17A, on number of new active brain magnetic resonance imaging (MRI) lesions in subjects with relapsing-remitting multiple sclerosis (MS). Subjects (N = 73) were randomized 1:1 to secukinumab 10 mg/...

journal_title：Journal of neurology

authors： Havrdová E,Belova A,Goloborodko A,Tisserant A,Wright A,Wallstroem E,Garren H,Maguire RP,Johns DR

更新日期：2016-07-01 00:00:00

abstract：:In patients with Parkinson's disease (PD) disturbances of mental state constitute some of the most difficult treatment challenges of advanced disease, often limiting effective treatment of motor symptoms and leading to increased disability and poor quality of life. This article provides an update on the current knowle...

journal_title：Journal of neurology

authors： Schrag A

更新日期：2004-07-01 00:00:00

abstract：:Parkinson's disease (PD) is a progressive neurological disorder characterized by motor symptoms as well as severe deficits in olfactory function and microstructural changes in olfactory brain regions. Because of the evidence of asymmetric neuropathological features in early-stage PD, we examined whether lateralized mi...

journal_title：Journal of neurology

authors： Joshi N,Rolheiser TM,Fisk JD,McKelvey JR,Schoffer K,Phillips G,Armstrong M,Khan MN,Leslie RA,Rusak B,Robertson HA,Good KP

更新日期：2017-07-01 00:00:00

abstract：:It has been approximately 50 years since neurologists were introduced to the entities, "progressive supranuclear palsy" and "corticobasal degeneration". Since the two seminal publications, there have been significant advancements in our understanding of these two neurodegenerative diseases, particularly the fact that ...

journal_title：Journal of neurology

authors： Josephs KA

更新日期：2015-03-01 00:00:00