Update on medications used to treat gastrointestinal disease in children.

abstract：PURPOSE OF REVIEW:The purpose of this review is to describe current concepts on inflammation, immunity and insulin resistance. Metabolic and immune systems are closely involved in inflammation and significantly contribute to the pathology seen in the pediatric intensive care unit. The ability of insulin to decrease hep...

journal_title：Current opinion in pediatrics

authors： Dhar A,Castillo L

更新日期：2011-06-01 00:00:00

abstract：PURPOSE OF REVIEW:This review will outline the screening, diagnosis and management of cystic fibrosis related diabetes (CFRD). It will also discuss advances in the detection of early glucose abnormalities, their clinical significance and the emerging role for early insulin therapy. RECENT FINDINGS:Before the onset of ...

journal_title：Current opinion in pediatrics

authors： Hameed S,Jaffé A,Verge CF

更新日期：2015-08-01 00:00:00

abstract：:The "win at all costs" mentality is becoming increasingly common in youth sports, and young athletes are often looking for methods to improve sports performance and avoid injury. As organized sports participation continues to increase among American adolescents, questions related to sports medicine are more frequently...

journal_title：Current opinion in pediatrics

authors： Metzl JD

更新日期：1999-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Considerable attention has recently been focused on the pathogenesis, diagnosis and treatment of osteogenesis imperfecta. Two new genes have been defined in patients with recessive severe or lethal osteogenesis imperfecta types. Diagnostic concerns involve testing procedures, either skin biopsies or D...

journal_title：Current opinion in pediatrics

authors： Shapiro JR,Sponsellor PD

更新日期：2009-12-01 00:00:00

abstract：PURPOSE OF REVIEW:We provide an overview of the past year's literature on congenital heart surgery. RECENT FINDINGS:This review focuses on selected disease entities, operative techniques, perioperative management strategies, and quality of care. SUMMARY:Congenital heart surgery is an evolving field. ...

journal_title：Current opinion in pediatrics

authors： Welke KF,Komanapalli C,Shen I,Ungerleider RM

更新日期：2005-10-01 00:00:00

abstract：PURPOSE OF REVIEW:This review highlights recent publications on the use of the Internet as it relates to pediatric primary care, including its application to the pediatrician, teen, pediatric patient, and patients' parents. A brief overview of early work is introduced. RECENT FINDINGS:The Internet has become a tool to...

journal_title：Current opinion in pediatrics

authors： Kind T

更新日期：2009-12-01 00:00:00

abstract：PURPOSE OF REVIEW:An understanding of vaccine safety is important for all immunization providers, who have responsibilities to identify, report, and prevent adverse events. RECENT FINDINGS:New analytic methods can provide more rapid information on adverse events compared with traditional observational studies. Some ad...

journal_title：Current opinion in pediatrics

authors： Wharton M

更新日期：2010-02-01 00:00:00

abstract：:This paper reviews recent studies of attention deficit-hyperactivity disorder, focusing on research with implications for adolescents. Only 10 of the 31 recent investigations discussed employed an exclusively adolescent sample, necessitating considerable extrapolation from studies of children or adults or mixed sample...

journal_title：Current opinion in pediatrics

authors： Phillips S,Soffer SL

更新日期：1996-08-01 00:00:00

abstract：PURPOSE OF REVIEW:This study reviews the history of neonatal drug development, recent legislative efforts designed to facilitate the study of therapeutic agents in neonates, and future steps necessary to advance drug development. RECENT FINDINGS:Although many federal regulations have been introduced over the past 15 y...

journal_title：Current opinion in pediatrics

authors： Smith AM,Davis JM

更新日期：2017-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Sepsis is the leading cause of pediatric death worldwide. In the United States alone, there are 72 000 children hospitalized for sepsis annually with a reported mortality rate of 25% and an economic cost estimated to be $4.8 billion. However, it is only recently that the definition and management of p...

journal_title：Current opinion in pediatrics

authors： Mathias B,Mira JC,Larson SD

更新日期：2016-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Femoroacetabular impingement (FAI) post slipped capital femoral epiphysis (SCFE) may lead to degenerative changes on the hip. We have reviewed the current procedures in the literature, aiming to correct the SCFE to prevent FAI and the ones that treat FAI post SCFE. RECENT FINDINGS:The trends of manag...

journal_title：Current opinion in pediatrics

authors： Soni JF,Valenza WR,Uliana CS

更新日期：2018-02-01 00:00:00

abstract：PURPOSE OF REVIEW:To familiarize primary care pediatricians with basic detection and treatment strategies of lower extremity stress fractures, while highlighting new research related to improving diagnosis and management approaches for pediatric and adolescent athletes. RECENT FINDINGS:Young age appears to be a risk f...

journal_title：Current opinion in pediatrics

authors： Heyworth BE,Green DW

更新日期：2008-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Complement mediated hemolytic uremic syndrome (aHUS) accounts for a significant proportion of non-shiga toxin HUS. The purpose of this review is to outline the pathophysiology, clinical features and therapeutic options for aHUS. RECENT FINDINGS:In the last decade, strides have been made in identifyin...

journal_title：Current opinion in pediatrics

authors： Joseph C,Gattineni J

更新日期：2013-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The current article highlights recent developments in the field of pediatric cutaneous mastocytosis. Mastocytosis is a spectrum of conditions that range from fleetingly benign to aggressively malignant. Through recognizing the natural progression of disease, the role of biomarkers and mutational analy...

journal_title：Current opinion in pediatrics

authors： Hussain SH

更新日期：2020-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The role of extracorporeal membrane oxygenation (ECMO), a method of providing cardiorespiratory support in instances of cardiac or respiratory failure, in neonates and children continues to expand and evolve. This review details the current landscape of ECMO as it applies to neonates and children. RE...

journal_title：Current opinion in pediatrics

authors： Etchill EW,Dante SA,Garcia AV

更新日期：2020-06-01 00:00:00

abstract：:Attention deficit hyperactivity disorder is one of the most common behavioral disorders of childhood and is frequently assessed and treated by pediatricians and other primary care physicians. The diagnosis of attention deficit hyperactivity disorder is based on the careful synthesis of clinical data derived from multi...

journal_title：Current opinion in pediatrics

authors： McGough JJ,McCracken JT

更新日期：2000-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Neurodevelopmental-behavioural paediatrics (NBP) is a field of medical practice that has arisen in response to recent changes in child health epidemiology. This review considers how the profession of NBP is addressing clinical need, and discusses possibilities for future development of the field. REC...

journal_title：Current opinion in pediatrics

authors： McDowell M,Lesslie J

更新日期：2019-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize the recommended work-up in a child who presents with elevated blood pressure as well as innovative evaluation techniques under development. RECENT FINDINGS:'The fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescents' contains several ...

journal_title：Current opinion in pediatrics

authors： Nguyen M,Mitsnefes M

更新日期：2007-04-01 00:00:00

abstract：:Three main factors are needed for an infant to develop allergy: allergen exposure, a genetic predisposition, and contributory factors. Recent literature suggests that the incidence of in utero sensitization might have been underestimated up to now. A number of papers provide evidence that atopic dermatitis should be r...

journal_title：Current opinion in pediatrics

authors： Vandenplas Y

更新日期：1993-10-01 00:00:00

abstract：:The biology of the X chromosome is unique, as there are two Xs in females and only a single X in males, whereas the autosomes are present in duplicate in both sexes. The presence of only a single autosome, which can occur as a result of an error in meiotic segregation, is invariably an embryonic lethal event. Monosomy...

journal_title：Current opinion in pediatrics

authors： Gartler SM,Goldman MA

更新日期：2001-08-01 00:00:00

abstract：:Atopic dermatitis is the most common chronic skin disease of young children and is frequently associated with asthma and allergies. Th2-type cytokine secreting T cells expressing the cutaneous lymphocyte-associated antigen play a central role in the induction of local IgE responses and recruitment of eosinophils in th...

journal_title：Current opinion in pediatrics

authors： Boguniewicz M

更新日期：1997-12-01 00:00:00

abstract：:This review summarizes recent literature regarding the clinical and molecular features of nonmalignant leukocyte disorders in children. Leukocyte adhesion deficiency and chronic granulomatous disease, two inherited disorders of neutrophil function, continue to be the best-characterized disorders with respect to specif...

journal_title：Current opinion in pediatrics

authors： Dinauer MC

更新日期：1993-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Nearing the end of the first decade of this new century, the challenges and changes in the field of outpatient pediatric cardiology continue to accelerate. RECENT FINDINGS:To help the general pediatrician and family practice physician become aware of several new care guidelines and practice trends as...

journal_title：Current opinion in pediatrics

authors： Lacina SJ

更新日期：2009-10-01 00:00:00

abstract：:Autoimmune Lymphoproliferative Syndrome (ALPS) is a recently recognized disease in which a genetic defect in programmed cell death, or apoptosis, leads to breakdown of lymphocyte homeostasis and normal immunologic tolerance. Some authors have referred to ALPS as Canale-Smith syndrome or lymphoproliferative syndrome wi...

journal_title：Current opinion in pediatrics

authors： Jackson CE,Puck JM

更新日期：1999-12-01 00:00:00

abstract：:Neonatal infections range from early-onset vertically acquired infections to nosocomial bacterial sepsis, and they account for significant morbidity and mortality globally. The recent emergence of perinatally acquired HIV-1 infection has also placed an enormous burden on existing meager health resources in developing ...

journal_title：Current opinion in pediatrics

authors： Bhutta ZA

更新日期：1997-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Osteoid osteoma is a benign painful bone tumor usually found in the lower extremities of children and young adults. It has been traditionally treated by surgical excision. Despite the small size of the lesion, the operative procedure for its removal can be extensive, but still sometimes remains incomp...

journal_title：Current opinion in pediatrics

authors： Ghanem I

更新日期：2006-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Altered epigenetics is central to oncogenesis in many pediatric cancers. Aberrant epigenetic states are induced by mutations in histones or epigenetic regulatory genes, aberrant expression of genes regulating chromatin complexes, altered DNA methylation patterns, or dysregulated expression of noncodin...

journal_title：Current opinion in pediatrics

authors： Panditharatna E,Filbin MG

更新日期：2020-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The current review will focus on the current knowledge of the contribution of both germline and somatic mutations to the development and management of cancer in pediatric patients. RECENT FINDINGS:It has long been thought that genetic mutations in both germline and somatic cells can contribute to the...

journal_title：Current opinion in pediatrics

authors： Dean SJ,Farmer M

更新日期：2017-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Increasing numbers of children are now traveling to high-altitude destinations, and pediatricians often see these children prior to and immediately following their travels. Thus, pediatricians have the opportunity to provide guidance for the prevention of altitude illness and must treat high-altitude ...

journal_title：Current opinion in pediatrics

authors： Garlick V,O'Connor A,Shubkin CD

更新日期：2017-08-01 00:00:00

abstract：PURPOSE OF REVIEW:This article reviews recent developments in the assessment of changes in structure and function in the fetal heart with the focus on congenital heart disease malformations. RECENT FINDINGS:Use of the combination of the cardiovascular profile score, the biophysical profile score and additional physiol...

journal_title：Current opinion in pediatrics

authors： Acharya G,Archer N,Huhta JC

更新日期：2007-10-01 00:00:00