Abstract:
:The objective of this study was to ascertain if stereotactic neurosurgical biopsy (SNB) optimizes the therapy of undefined CNS masses. The design was of retrospective treatment and outcome analysis and the setting was a large general hospital. We studied a total of 141 patients with undefined, space-occupying CNS lesions detected between 1991-1997, with whom we used SNB to define the lesions. We sought to correlate empiric and histological diagnostics and their impact on medical management. The stereotactic biopsy produced a diagnostic yield for each patient. Management was altered in 57 cases (40%) due to histology and, of these, malignancy was found in 39. Morbidity was ten asymptomatic hemorrhages on post-biopsy CT scans and two cases of clinical deterioration. Our conclusions were that SNB produces high yield with low morbidity. In the community setting, a wide variety of diagnoses can be made with improvements in medical management. SNB should be employed to guide therapy of CNS lesions where complete excision is not possible or when diagnostic questions arise.
journal_name
Neurosurg Revjournal_title
Neurosurgical reviewauthors
Plunkett R,Allison RR,Grand Wdoi
10.1007/s101430050043keywords:
subject
Has Abstractpub_date
1999-10-01 00:00:00pages
117-20issue
2-3eissn
0344-5607issn
1437-2320journal_volume
22pub_type
杂志文章abstract::Damage which occurs following spinal traumas is often irreversible. During recent years free oxygen radicals formed due to the pathological changes following neural tissue ischemia have been identified as being responsible for the ethio-pathogenesis of such damage. In our experimental study, model lesions are formed i...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/BF00308614
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journal_title:Neurosurgical review
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journal_title:Neurosurgical review
pub_type: 杂志文章
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journal_title:Neurosurgical review
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journal_title:Neurosurgical review
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journal_title:Neurosurgical review
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journal_title:Neurosurgical review
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pub_type: 杂志文章
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journal_title:Neurosurgical review
pub_type: 杂志文章
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journal_title:Neurosurgical review
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journal_title:Neurosurgical review
pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
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pub_type: 杂志文章,meta分析,评审
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pub_type: 杂志文章
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journal_title:Neurosurgical review
pub_type: 杂志文章
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journal_title:Neurosurgical review
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journal_title:Neurosurgical review
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pub_type: 杂志文章,评审
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