Abstract:
:Urinary cotinine was measured according to its inhibitory activity on the agglutination of cotinine-coated latex particles by anti-cotinine antibodies, the agglutination being measured by optical counting of the remaining non-agglutinated particles (particle counting, PaC). The detection limit was 0.03 microgram/ml and the practical range extended from 0.03 to 3.9 micrograms/ml. The correlation results of 320 urine samples with those of high pressure liquid chromatography, enzyme-linked (Coti-Tracq EIA, Serex Inc., Maywood, NJ, USA), and fluorescence polarization immunoassay (TDX instrument, Abbott, Abbott Park, IL, USA) were r = 0.90, r = 0.69, r = 0.87, respectively, whereas the correlation coefficients between the assays other than particle counting ranged from 0.62 to 0.88. PaC does not require any separation step and can thus be easily automated.
journal_name
Clin Chem Lab Medjournal_title
Clinical chemistry and laboratory medicineauthors
Galanti LM,Dell'Omo J,Vanbeckbergen D,Dubois P,Masson PL,Cambiaso CLdoi
10.1515/CCLM.1999.112keywords:
subject
Has Abstractpub_date
1999-07-01 00:00:00pages
729-34issue
7eissn
1434-6621issn
1437-4331journal_volume
37pub_type
杂志文章abstract::Carbohydrate-deficient transferrin (CDT) is a descriptive term used for a temporary change in the transferrin glycosylation profile caused by alcohol, and used as a biomarker of chronic high alcohol consumption. The use of an array of methods for measurement of CDT in various absolute or relative amounts, and sometime...
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pub_type: 杂志文章
doi:10.1515/CCLM.2008.288
更新日期:2008-01-01 00:00:00
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pub_type: 杂志文章,评审
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journal_title:Clinical chemistry and laboratory medicine
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更新日期:2007-01-01 00:00:00
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更新日期:2020-07-28 00:00:00
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journal_title:Clinical chemistry and laboratory medicine
pub_type: 杂志文章,随机对照试验
doi:10.1515/cclm-2018-0430
更新日期:2018-11-27 00:00:00
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journal_title:Clinical chemistry and laboratory medicine
pub_type: 杂志文章,评审
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更新日期:1998-08-01 00:00:00
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journal_title:Clinical chemistry and laboratory medicine
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doi:10.1515/CCLM.2009.228
更新日期:2009-01-01 00:00:00
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journal_title:Clinical chemistry and laboratory medicine
pub_type: 杂志文章
doi:10.1515/CCLM.1999.023
更新日期:1999-02-01 00:00:00
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doi:10.1515/CCLM.2006.205
更新日期:2006-01-01 00:00:00