Abstract:
:A total of 227 marine isolates of ubiquitous fungi were cultivated on different media and the secondary metabolite content of the extracts (ethyl acetate/chloroform/methanol 3:2:1) characterized by HPLC. The fungi were secured from animals, plants and sediments of Venezuelan waters (0-10 m) including mangroves and lagoonal areas. The extracts were tested for antibacterial activity. A total of 7 were active towards Vibrio parahaemolyticus and 55 towards Staphylococcus aureus, representing 18 different fungal species from 8 ascomycetous genera. For 61 strains of Penicillium citrinum antibacterial activity correlated well with content of secondary metabolites as measured by HPLC. Thirteen isolates of Penicillium steckii produced very similar profiles of secondary metabolites and 6 of these had activity against either V. parahaemolyticus or S. aureus or both.
journal_name
Mycopathologiajournal_title
Mycopathologiaauthors
Christophersen C,Crescente O,Frisvad JC,Gram L,Nielsen J,Nielsen PH,Rahbaek Ldoi
10.1023/a:1006961500325keywords:
subject
Has Abstractpub_date
1998-01-01 00:00:00pages
135-8issue
3eissn
0301-486Xissn
1573-0832journal_volume
143pub_type
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