Abstract:
:Early and late age-related macular degeneration (AMD) have a high prevalence in elderly patients but may be differentiated by medical or environmental factors, eg, hypertension, geographic area, or antioxidant agents. Because nuclear sclerotic cataract is associated with AMD both aging changes may share a common pathogenesis. The genetic predisposition for AMD is indicated by the identical appearance in monozygotic twins, but genetics may be also important for the explanation of the low incidence of late AMD in black individuals. Specific ocular characteristics like light or depigmented iris color, prolonged dark adaptation, and decreased foveal flicker sensitivity are also risk factors for AMD. Early AMD characteristics with high risk for late AMD are confluent drusen, focal hyperpigmentation, or atrophy and slow choroidal fluorescein filling. Therefore specific genetic, environmental, medical, and ocular characteristics determine the individual appearance and progress of AMD. The knowledge of these factors may result in new prophylactic and specific treatments for AMD.
journal_name
Curr Opin Ophthalmoljournal_title
Current opinion in ophthalmologyauthors
Pauleikhoff D,Koch JMdoi
10.1097/00055735-199506000-00009keywords:
subject
Has Abstractpub_date
1995-06-01 00:00:00pages
51-6issue
3eissn
1040-8738issn
1531-7021journal_volume
6pub_type
杂志文章,评审abstract::Both classic descriptions and new findings in human anatomy have been limited in the past to cadaveric dissections. Although dissection still supplies most of new information, refinements in technique and the advent of high-resolution soft tissue imaging available with magnetic resonance have certainly provided a new ...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-199510000-00010
更新日期:1995-10-01 00:00:00
abstract:PURPOSE OF REVIEW:Asians make up the world's largest ethnic group, and the eyelid is one of the most prominent features of the face, regardless of race. Recent advances in Asian eyelid research have improved the understanding of its unique anatomy and, more importantly, highlighted differences surgeons should be aware ...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0000000000000075
更新日期:2014-09-01 00:00:00
abstract:PURPOSE OF REVIEW:Corneal collagen cross-linking has recently emerged as a novel approach for management of ectasia. This article reviews the literature published in the past 3 years about the expanding spectrum of cross-linking as a therapeutic modality and its complications. RECENT FINDINGS:Recent studies have confi...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0b013e328354865e
更新日期:2012-07-01 00:00:00
abstract::This review of recent articles on ocular toxicology concentrates on undesirable effects on the eye induced by systemically used xenobiotics. These include color vision deficiencies or visual field deterioration related to antiepileptic drugs, elevated intraocular pressure associated with inhaled corticosteroids, retin...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-199712000-00016
更新日期:1997-12-01 00:00:00
abstract:PURPOSE OF REVIEW:Significant advances have been made in oncology and rheumatology with the introduction of molecularly targeted agents (MTAs). MTAs consist of monoclonal antibodies and small molecule inhibitors. The purpose of this manuscript is to review the recent applications of MTAs to orbital, lacrimal, and eyeli...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0000000000000403
更新日期:2017-09-01 00:00:00
abstract:PURPOSE OF REVIEW:To discuss the risks, benefits and value of genetic testing for ocular genetic disease. RECENT FINDINGS:Testing for ocular genetics diseases is becoming more available and successful gene therapy is being reported. Clinicians must prepare for this trend by considering diagnostic genetic testing for t...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0000000000000083
更新日期:2014-09-01 00:00:00
abstract::Acute demyelinating optic neuritis associated with multiple sclerosis (MS) is the most common cause of inflammation of the optic nerve. The Optic Neuritis Treatment Trial (ONTT) has provided important clinical data on the use of corticosteroids, and demonstrated that patients with characteristic inflammatory lesions w...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-200212000-00006
更新日期:2002-12-01 00:00:00
abstract:PURPOSE OF REVIEW:The Residency Review Committee Ophthalmology of the Accreditation Council for Graduate Medical Education has recently established guidelines pertaining to the minimum operative requirements for training ophthalmology residents in refractive surgery. Despite being one of the most frequently performed o...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0b013e32833a8967
更新日期:2010-07-01 00:00:00
abstract:PURPOSE OF REVIEW:The Charles Bonnet syndrome is a disorder of visual hallucinations typically occurring in older persons with vision impairment or deafferentation of the visual cortex. This review cites recent studies on Charles Bonnet syndrome and discusses treatment options. The numbers of affected persons will incr...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/01.icu.0000193100.13551.ac
更新日期:2006-06-01 00:00:00
abstract::Retinopathy of prematurity (ROP) is a potentially blinding condition that afflicts preterm infants in the neonatal period. Although advances in scleral buckling and vitrectomy techniques offer hope for those infants suffering from stage 4 or 5 ROP, prevention of progression to these stages offers the most promise for ...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-200106000-00003
更新日期:2001-06-01 00:00:00
abstract:PURPOSE OF REVIEW:Endoresection of intraocular tumors is a complicated procedure utilizing pars plana vitrectomy techniques. Though it has potential downsides and complications, there is potential for this technique in the treatment of malignant and benign intraocular tumors. RECENT FINDINGS:Endoresection has been uti...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0000000000000561
更新日期:2019-05-01 00:00:00
abstract::Using a liberal definition of corneal irregularity, modern videokeratoscopy may define approximately 40% of normal corneas with a toric refractive error as possessing primary irregular astigmatism. The causes of secondary forms of irregular astigmatism include corneal surgery, trauma, dystrophies, and infections. Inte...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-200008000-00007
更新日期:2000-08-01 00:00:00
abstract:PURPOSE OF REVIEW:Intraocular lens (IOL) calculations in patients with keratoconus and other keratoectatic disorders continues to be a challenge for today's cataract surgeon. In this article, we review data published over the past 18 months (June 2018 to January 2020). RECENT FINDINGS:Cataract surgery in keratoconus p...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0000000000000671
更新日期:2020-07-01 00:00:00
abstract:PURPOSE OF REVIEW:Posterior vitreous detachment is the principal predisposing event for the development of retinal breaks and rhegmatogenous retinal detachments. Patients with unilateral posterior vitreous detachment are potentially at risk of developing the complications associated with posterior vitreous detachment i...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0b013e3281299022
更新日期:2007-05-01 00:00:00
abstract:PURPOSE OF REVIEW:Diabetic retinopathy and diabetic macular edema (DME) are common eye diseases leading to vision loss. The Diabetic Retinopathy Clinical Research Network (DRCRnet), a collaboration of private and academic practices supported by the National Eye Institute and the National Institute of Diabetes, Digestiv...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0000000000000262
更新日期:2016-05-01 00:00:00
abstract:PURPOSE OF REVIEW:Recent advances in the design and material of phakic intraocular lenses have made them very predictable, safe and effective. The use of these lenses in refractive surgery is expected to increase very significantly in the near future. The aim of this review is to update the reader regarding the recent ...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0b013e3283009f0a
更新日期:2008-07-01 00:00:00
abstract:PURPOSE OF REVIEW:Scleral rigid gas-permeable lenses play an important and underappreciated role in the treatment of corneal disease. This review provides an update on scleral rigid gas-permeable lenses for the visual rehabilitation of ectasia and irregular astigmatism, and an update on scleral rigid gas-permeable lens...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0b013e328302cc4f
更新日期:2008-07-01 00:00:00
abstract:PURPOSE OF REVIEW:The recent literature was reviewed to analyze the developments in the diagnosis, pathogenesis, and immunology of this group of paraneoplastic syndromes. Clinical features and pathologic findings are summarized. RECENT FINDINGS:The mechanism of cell death in cancer-associated retinopathy appears to oc...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-200312000-00017
更新日期:2003-12-01 00:00:00
abstract:PURPOSE OF REVIEW:The phaco machine is frequently overlooked as the crucial surgical instrument it is. Understanding how to set parameters is initiated by understanding fundamental concepts of machine function. RECENT FINDINGS:This study analyses the critical concepts of partial occlusion phaco, occlusion phaco and pu...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0b013e32835b0770
更新日期:2013-01-01 00:00:00
abstract::Healing of corneal wounds is a complex process involving epithelial, keratocyte, and endothelial interactions that are affected by their associations with wound bed matrix and by cytokine availability and activation. The spectrum of possible cellular-matrix-growth factor interactions is indeed great and growing. Sever...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-199508000-00002
更新日期:1995-08-01 00:00:00
abstract:PURPOSE OF REVIEW:To perform a literature review of articles published between 2016 and 2017 to assess recent advances in intraocular lens (IOL) selection. RECENT FINDINGS:A literature review revealed five areas of recent study including advances in biometric technology, formula selection for challenging eyes, accurat...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0000000000000493
更新日期:2018-07-01 00:00:00
abstract::Cystoid macular edema (CME) remains a troublesome problem after cataract surgery and other types of ocular surgical procedures. It is recognized as the most frequent cause of decreased vision in patients following cataract surgery. Although the disease was first described more than 40 years ago, its cause is unclear, ...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-200002000-00010
更新日期:2000-02-01 00:00:00
abstract::Outcome measures for studies of the surgical treatment of glaucoma include intraocular pressure, functional status (usually with visual field measurements), and structural status of the optic nerve or nerve fiber layer. Older studies relied heavily and almost solely on intraocular pressure as a surrogate measure for e...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-199704000-00013
更新日期:1997-04-01 00:00:00
abstract:PURPOSE OF THE REVIEW:Cataract surgery induces considerable vitreous modifications that can lead to posterior vitreous detachment. Studies indicate that these changes, whether combined or not with peripheral retinal degenerations such as lattice areas, carry risk for subsequent retinal breaks or detachment. RECENT FIN...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0b013e3282fc9c4a
更新日期:2008-05-01 00:00:00
abstract::Since the publication of my last article in Current Opinion in Ophthalmology in 1991 (2:33-34), the use of multifocal intraocular lenses (IOLs) has not gained general acceptance among ophthalmologists. Despite this situation, major IOL companies have continued to invest in clinical trials of new designs. Recently, lar...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:
更新日期:1996-02-01 00:00:00
abstract:PURPOSE OF REVIEW:Fine-needle aspiration biopsy of choroidal melanoma offers an opportunity to determine the prognosis for metastasis and provide tissue resources for further study to develop molecular-based targeted therapies. Patients increasingly desire as much information as possible about their cancer so that they...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0b013e32835ff001
更新日期:2013-05-01 00:00:00
abstract::Patients with Alzheimer's disease may present to the ophthalmologist with visual symptoms that precede or overshadow the features of dementia. This visual variant of Alzheimer's disease has been recognized only recently and typically appears in late middle age as progressive visuospatial and reading dysfunction, with ...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:
更新日期:1994-12-01 00:00:00
abstract:PURPOSE OF REVIEW:To discuss a new class of medication that has recently become available for the treatment of glaucoma; as well as share insights into developments in glaucoma medicine administration which has the potential to revolutionize medical therapy for glaucoma. RECENT FINDINGS:Newly available eye drops, neta...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章
doi:10.1097/ICU.0000000000000740
更新日期:2020-12-30 00:00:00
abstract:PURPOSE OF REVIEW:Cataract surgery in India has seen exponential growth in the past decade. This leap was possible due to cost-effective cataract surgery with intraocular lenses. The purpose of this review is to update the reader regarding the Indian scenario of cataract surgery and intraocular lens manufacturing. REC...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0b013e3282f2aaed
更新日期:2008-01-01 00:00:00
abstract::Clonidine hydrochloride, apraclonidine hydrochloride, and brimonidine tartrate constitute the three topical alpha agonists that are used in the treatment of elevated intraocular pressure. All the alpha agonists have prejunctional (alpha 2) as well as postjunctional (alpha 1) effects. Within the past year, questions ha...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-199804000-00006
更新日期:1998-04-01 00:00:00