Cognitive-behavioral therapy helps prevent relapse and recurrence of panic disorder following alprazolam discontinuation: a long-term follow-up of the Peoria and Dartmouth studies.

Abstract:

:The present research evaluated patients from 2 previous studies (1 conducted in Peoria, the other at Dartmouth) during a 2- to 5-year posttreatment period. Results showed that 75% of the Peoria sample and 76% of the Dartmouth sample were able to discontinue alprazolam therapy, remain abstinent of any type of treatment for panic disorder, and maintain their acute-treatment clinical gains over this follow-up period. The degree to which patients' anxiety sensitivity declined during treatment predicted relapse versus survival during the 1st 6 months of follow-up, when most relapses occurred. Implications of these findings for benzodiazepine discontinuation, combined pharmacotherapy and psychotherapy, and relapse prevention in panic disorder are discussed.

journal_name

J Consult Clin Psychol

authors

Bruce TJ,Spiegel DA,Hegel MT

doi

10.1037//0022-006x.67.1.151

keywords:

subject

Has Abstract

pub_date

1999-02-01 00:00:00

pages

151-6

issue

1

eissn

0022-006X

issn

1939-2117

journal_volume

67

pub_type

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