Abstract:
:Proton exchange provides a powerful contrast mechanism for magnetic resonance imaging (MRI). MRI techniques sensitive to proton exchange provide new opportunities to map, with high spatial and temporal resolution, compounds important for brain metabolism and function. Two such techniques, chemical exchange saturation transfer (CEST) and T1 relaxation in the rotating frame (T1ρ), are emerging as promising tools in the study of neurological and psychiatric illnesses to study brain metabolism. This review describes proton exchange for non-experts, highlights the current status of proton-exchange MRI, and presents advantages and drawbacks of these techniques compared to more traditional methods of imaging brain metabolism, including positron emission tomography (PET) and MR spectroscopy (MRS). Finally, this review highlights new frontiers for the use of CEST and T1ρ in brain research.
journal_name
Front Psychiatryjournal_title
Frontiers in psychiatryauthors
Shaffer JJ Jr,Mani M,Schmitz SL,Xu J,Owusu N,Wu D,Magnotta VA,Wemmie JAdoi
10.3389/fpsyt.2020.532606subject
Has Abstractpub_date
2020-09-24 00:00:00pages
532606issn
1664-0640journal_volume
11pub_type
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doi:10.3389/fpsyt.2018.00722
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abstract:Background:Gastric necrosis following acute gastric dilatation is rare but more common in females with eating disorders, such as anorexia nervosa or bulimia, during which patients often alternate restriction and binge eating behaviors. Case Presentation:A 37-year old female patient with a history of 15 years of bulimi...
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abstract:Background:Patients with schizophrenia and individuals at ultra-high risk for psychosis (UHR) have been reported to exhibit impaired recognition of facial emotion expressions. This impairment has involved both inaccuracy and negative bias of facial emotion recognition. The present study aimed to investigate whether UHR...
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journal_title:Frontiers in psychiatry
pub_type: 杂志文章,评审
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abstract::There is accruing evidence of cerebellar abnormalities in schizophrenia. The theory of cognitive dysmetria considers cerebellar dysfunction a key component of schizophrenia. Delay eyeblink conditioning (EBC), a cerebellar-dependent translational probe, is a behavioral index of cerebellar integrity. The circuitry under...
journal_title:Frontiers in psychiatry
pub_type: 杂志文章,评审
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pub_type: 杂志文章
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pub_type: 杂志文章,评审
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journal_title:Frontiers in psychiatry
pub_type: 杂志文章
doi:10.3389/fpsyt.2020.00786
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pub_type: 杂志文章
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journal_title:Frontiers in psychiatry
pub_type: 杂志文章,评审
doi:10.3389/fpsyt.2018.00564
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pub_type: 杂志文章
doi:10.3389/fpsyt.2011.00038
更新日期:2011-06-28 00:00:00
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pub_type: 杂志文章
doi:10.3389/fpsyt.2020.602315
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journal_title:Frontiers in psychiatry
pub_type: 杂志文章
doi:10.3389/fpsyt.2020.00832
更新日期:2020-08-31 00:00:00
abstract::[This corrects the article DOI: 10.3389/fpsyt.2020.00202.]. ...
journal_title:Frontiers in psychiatry
pub_type: 已发布勘误
doi:10.3389/fpsyt.2020.00300
更新日期:2020-04-23 00:00:00
abstract::Autism spectrum disorder (ASD) and schizophrenia (SZ) are heterogenous neurodevelopmental disorders that overlap in symptom presentation. The purpose of this study was to specify overlapping symptom domains and to identify symptoms that can reliably differentiate adults with ASD (n = 53), SZ (n = 39), and typical deve...
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pub_type: 杂志文章
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journal_title:Frontiers in psychiatry
pub_type: 杂志文章
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journal_title:Frontiers in psychiatry
pub_type: 杂志文章
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pub_type: 杂志文章
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pub_type: 杂志文章
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