Topological View of Flows Inside the BOLD Spontaneous Activity of the Human Brain.

abstract：:Parkinson's disease (PD) is a neurodegenerative disorder which follows from cell loss of dopaminergic neurons in the substantia nigra pars compacta (SNc), a nucleus in the basal ganglia (BG). Deep brain stimulation (DBS) is an electrical therapy that modulates the pathological activity to treat the motor symptoms of P...

journal_title：Frontiers in computational neuroscience

authors： Summerson SR,Aazhang B,Kemere C

更新日期：2015-06-26 00:00:00

abstract：:Brain computer interfaces allow users to preform various tasks using only the electrical activity of the brain. BCI applications often present the user a set of stimuli and record the corresponding electrical response. The BCI algorithm will then have to decode the acquired brain response and perform the desired task....

journal_title：Frontiers in computational neuroscience

authors： Manor R,Mishali L,Geva AB

更新日期：2016-12-20 00:00:00

abstract：:Often we need to perform tasks in an environment that changes stochastically. In these situations it is important to learn the statistics of sequences of events in order to predict the future and the outcome of our actions. The statistical description of many of these sequences can be reduced to the set of probabiliti...

journal_title：Frontiers in computational neuroscience

authors： Ostojic S,Fusi S

更新日期：2013-04-12 00:00:00

abstract：:Glucose is the brain's principal source of ATP, but the extent to which cerebral glucose consumption (CMRglc) is coupled with its oxygen consumption (CMRO2) remains unclear. Measurements of the brain's oxygen-glucose index OGI = CMRO2/CMRglc suggest that its oxygen uptake largely suffices for oxidative phosphorylation...

journal_title：Frontiers in computational neuroscience

authors： Angleys H,Jespersen SN,Østergaard L

更新日期：2016-10-13 00:00:00

abstract：:In vivo and in vitro experimental studies have found that blocking electrical interactions connecting GABAergic interneurons reduces oscillatory activity in the gamma range in cortex. However, recent theoretical works have shown that the ability of electrical synapses to promote or impede synchrony, when alone, depend...

journal_title：Frontiers in computational neuroscience

authors： Pfeuty B,Golomb D,Mato G,Hansel D

更新日期：2007-11-02 00:00:00

abstract：:We present a high-capacity model for one-shot association learning (hetero-associative memory) in sparse networks. We assume that basic patterns are pre-learned in networks and associations between two patterns are presented only once and have to be learned immediately. The model is a combination of an Amit-Fusi like ...

journal_title：Frontiers in computational neuroscience

authors： Einarsson H,Lengler J,Steger A

更新日期：2014-11-07 00:00:00

abstract：:Previous studies have shown that the auditory cortex can enhance the perception of behaviorally important sounds in the presence of background noise, but the mechanisms by which it does this are not yet elucidated. Rapid plasticity of spectrotemporal receptive fields (STRFs) in the primary (A1) cortical neurons is obs...

journal_title：Frontiers in computational neuroscience

authors： Chambers JD,Elgueda D,Fritz JB,Shamma SA,Burkitt AN,Grayden DB

更新日期：2019-05-24 00:00:00

abstract：:Two important stimulus features represented within the rodent barrel cortex are velocity and angular direction of whisker deflection. Each cortical barrel receives information from thalamocortical (TC) cells that relay information from a single whisker, and TC input is decoded by barrel regular-spiking (RS) cells thro...

journal_title：Frontiers in computational neuroscience

authors： Patel MJ

更新日期：2018-06-12 00:00:00

abstract：:Neuronal action potentials or spikes provide a long-range, noise-resistant means of communication between neurons. As point processes single spikes contain little information in themselves, i.e., outside the context of spikes from other neurons. Moreover, they may fail to cross a synapse. A burst, which consists of a ...

journal_title：Frontiers in computational neuroscience

authors： Zeldenrust F,Wadman WJ,Englitz B

更新日期：2018-07-06 00:00:00

abstract：:Feature extraction is an important step in the process of electroencephalogram (EEG) signal classification. The authors propose a "pattern recognition" approach that discriminates EEG signals recorded during different cognitive conditions. Wavelet based feature extraction such as, multi-resolution decompositions into ...

journal_title：Frontiers in computational neuroscience

authors： Amin HU,Mumtaz W,Subhani AR,Saad MNM,Malik AS

更新日期：2017-11-21 00:00:00

abstract：:The inverse problem for estimating model parameters from brain spike data is an ill-posed problem because of a huge mismatch in the system complexity between the model and the brain as well as its non-stationary dynamics, and needs a stochastic approach that finds the most likely solution among many possible solutions...

journal_title：Frontiers in computational neuroscience

authors： Hoang H,Yamashita O,Tokuda IT,Sato MA,Kawato M,Toyama K

更新日期：2015-05-21 00:00:00

abstract：:Pitch is a perceptual correlate of periodicity. Sounds with distinct spectra can elicit the same pitch. Despite the importance of pitch perception, understanding the cellular mechanism of pitch perception is still a major challenge and a mechanistic model of pitch is lacking. A multi-stage neuronal network model is de...

journal_title：Frontiers in computational neuroscience

authors： Huang C,Rinzel J

更新日期：2016-06-16 00:00:00

abstract：:Based on a modified neural field network model composed of cortex and thalamus, we here propose a computational framework to investigate the onset control of absence seizure, which is characterized by the spike-wave discharges. Firstly, we briefly demonstrate the existence of various transition types in Taylor's model...

journal_title：Frontiers in computational neuroscience

authors： Liu S,Wang Q,Fan D

更新日期：2016-04-05 00:00:00

abstract：:Abnormal neuronal synchrony plays an important role in a number of brain diseases. To specifically counteract abnormal neuronal synchrony by desynchronization, Coordinated Reset (CR) stimulation, a spatiotemporally patterned stimulation technique, was designed with computational means. In neuronal networks with spike ...

journal_title：Frontiers in computational neuroscience

authors： Zeitler M,Tass PA

更新日期：2016-05-17 00:00:00

abstract：:In synapses, calcium is required for modulating synaptic transmission, plasticity, synaptogenesis, and synaptic pruning. The regulation of calcium dynamics within neurons involves cellular mechanisms such as synaptically activated channels and pumps, calcium buffers, and calcium sequestrating organelles. Many experime...

journal_title：Frontiers in computational neuroscience

authors： Hu E,Mergenthal A,Bingham CS,Song D,Bouteiller JM,Berger TW

更新日期：2018-07-27 00:00:00

abstract：:In this article, we describe and analyze the chaotic behavior of a conductance-based neuronal bursting model. This is a model with a reduced number of variables, yet it retains biophysical plausibility. Inspired by the activity of cold thermoreceptors, the model contains a persistent Sodium current, a Calcium-activate...

journal_title：Frontiers in computational neuroscience

authors： Xu K,Maidana JP,Caviedes M,Quero D,Aguirre P,Orio P

更新日期：2017-03-10 00:00:00

abstract：:The morphology of presynaptic specializations can vary greatly ranging from classical single-release-site boutons in the central nervous system to boutons of various sizes harboring multiple vesicle release sites. Multi-release-site boutons can be found in several neural contexts, for example at the neuromuscular junc...

journal_title：Frontiers in computational neuroscience

authors： Knodel MM,Geiger R,Ge L,Bucher D,Grillo A,Wittum G,Schuster CM,Queisser G

更新日期：2014-09-09 00:00:00

abstract：:The problem of cancer risk analysis is of great importance to health-service providers and medical researchers. In this study, we propose a novel Artificial Neural Network (ANN) algorithm based on the probabilistic framework, which aims to investigate patient patterns associated with their disease development. Compare...

journal_title：Frontiers in computational neuroscience

authors： Yang C,Yang J,Liu Y,Geng X

更新日期：2020-07-21 00:00:00

abstract：:Calcium concentrations as well as time courses have been used to model the signaling cascades leading to changes in the strength of synaptic connections. Previous models consider the dendritic spines as uniform compartments regarding calcium signaling. However, calcium concentrations can vary drastically on distances ...

journal_title：Frontiers in computational neuroscience

authors： Mihalas S

更新日期：2011-01-13 00:00:00

abstract：:Head direction cells fire to signal the direction in which an animal's head is pointing. They are able to track head direction using only internally-derived information (path integration)In this simulation study we investigate the factors that affect path integration accuracy. Specifically, two major limiting factors ...

journal_title：Frontiers in computational neuroscience

authors： Page HJ,Walters D,Stringer SM

更新日期：2015-02-06 00:00:00

abstract：:Behavioral studies have shown spatial working memory impairment with aging in several animal species, including humans. Persistent activity of layer 3 pyramidal dorsolateral prefrontal cortex (dlPFC) neurons during delay periods of working memory tasks is important for encoding memory of the stimulus. In vitro studies...

journal_title：Frontiers in computational neuroscience

authors： Ibañez S,Luebke JI,Chang W,Draguljić D,Weaver CM

更新日期：2020-01-17 00:00:00

abstract：:Predictive coding appears to be one of the fundamental working principles of brain processing. Amongst other aspects, brains often predict the sensory consequences of their own actions. Predictive coding resembles Kalman filtering, where incoming sensory information is filtered to produce prediction errors for subsequ...

journal_title：Frontiers in computational neuroscience

authors： Kneissler J,Drugowitsch J,Friston K,Butz MV

更新日期：2015-04-30 00:00:00

abstract：:Common computational principles underlie processing of various visual features in the cortex. They are considered to create similar patterns of contextual modulations in behavioral studies for different features as orientation and direction of motion. Here, I studied the possibility that a single theoretical framework...

journal_title：Frontiers in computational neuroscience

authors： Tzvetanov T

更新日期：2012-05-22 00:00:00

abstract：:Although the representation of space is as fundamental to visual processing as the representation of shape, it has received relatively little attention from neurophysiological investigations. In this study we characterize representations of space within visual cortex, and examine how they differ in a first direct comp...

journal_title：Frontiers in computational neuroscience

authors： Sereno AB,Lehky SR

更新日期：2011-02-01 00:00:00

abstract：:Stability is an important dynamical property of complex systems and underpins a broad range of coherent self-organized behavior. Based on evidence that some neurological disorders correspond to linear instabilities, we hypothesize that stability constrains the brain's electrical activity and influences its structure a...

journal_title：Frontiers in computational neuroscience

authors： Gray RT,Robinson PA

更新日期：2013-04-12 00:00:00

abstract：:A classic problem in neuroscience is how temporal sequences (TSs) can be recognized. This problem is exemplified in the olfactory system, where an odor is defined by the TS of olfactory bulb (OB) output that occurs during a sniff. This sequence is discrete because the output is subdivided by gamma frequency oscillatio...

journal_title：Frontiers in computational neuroscience

authors： Sanders H,Kolterman BE,Shusterman R,Rinberg D,Koulakov A,Lisman J

更新日期：2014-09-17 00:00:00

abstract：:Dynamics of a homogeneous neural population interacting with active extracellular medium were considered. The corresponding mathematical model was tuned specifically to describe the behavior of interneurons with tonic GABA conductance under the action of non-stationary ambient GABA. The feedback provided by the GABA m...

journal_title：Frontiers in computational neuroscience

authors： Adamchik DA,Matrosov VV,Kazantsev VB

更新日期：2018-04-05 00:00:00

abstract：:Neurons innervate space by extending axonal and dendritic arborizations. When axons and dendrites come in close proximity of each other, synapses between neurons can be formed. Neurons vary greatly in their morphologies and synaptic connections with other neurons. The size and shape of the arborizations determine the ...

journal_title：Frontiers in computational neuroscience

authors： van Pelt J,van Ooyen A

更新日期：2013-11-25 00:00:00

abstract：:The emergence of motion sensors as a tool that provides objective motor performance data on individuals afflicted with Parkinson's disease offers an opportunity to expand the horizon of clinical care for this neurodegenerative condition. Subjective clinical scales and patient based motor diaries have limited clinometr...

journal_title：Frontiers in computational neuroscience

authors： Ramdhani RA,Khojandi A,Shylo O,Kopell BH

更新日期：2018-09-11 00:00:00

abstract：:This paper proposed a new method to determine the neuronal tuning curves for maximum information efficiency by computing the optimum firing rate distribution. Firstly, we proposed a general definition for the information efficiency, which is relevant to mutual information and neuronal energy consumption. The energy co...

journal_title：Frontiers in computational neuroscience

authors： Han F,Wang Z,Fan H

更新日期：2017-02-21 00:00:00