Topical Application of Wogonin Provides a Novel Treatment of Knee Osteoarthritis.

abstract：:Dentin dysplasia (DD) and dentinogenesis imperfecta (DGI) patients have abnormal structure, morphology, and function of dentin. DD-II, DGI-II, and DGI-III are caused by heterozygous mutations in the dentin sialophosphoprotein (DSPP) gene in humans. Evidences have shown that loss of function of DSPP in Dspp knockout mi...

journal_title：Frontiers in physiology

authors： Shi C,Ma N,Zhang W,Ye J,Shi H,Xiang D,Wu C,Song L,Zhang N,Liu Q

更新日期：2020-11-09 00:00:00

abstract：:Aim: Acute ingestion of alcohol is often accompanied by cardiovascular dysregulation, malaise and even syncope. The full hemodynamic and cutaneous responses to the combination of alcohol and sugar (i.e., alcopops), a common combination in young people, and the mechanisms for the propensity to orthostatic intolerance a...

journal_title：Frontiers in physiology

authors： Maufrais C,Charriere N,Montani JP

更新日期：2017-11-10 00:00:00

abstract：:While it is widely known that marine mammals possess adaptations which allow them to make repetitive and extended dives to great depths without suffering ill effects seen in humans, the response of marine mammal immune cells to diving is unknown. Renewed interest in marine mammal dive physiology has arisen due to repo...

journal_title：Frontiers in physiology

authors： Thompson LA,Romano TA

更新日期：2015-05-06 00:00:00

abstract：:In cardiac tissues, the expression of multiple connexins (Cx40, Cx43, Cx45, and Cx30.2) is a requirement for proper development and function. Gap junctions formed by these connexins have distinct permeability and gating mechanisms. Since a single cell can express more than one connexin isoform, the formation of hetero...

journal_title：Frontiers in physiology

authors： Zhong G,Akoum N,Appadurai DA,Hayrapetyan V,Ahmed O,Martinez AD,Beyer EC,Moreno AP

更新日期：2017-05-29 00:00:00

abstract：:For many model organisms traditionally in use for cardiac electrophysiological studies, characterization of ion channel genes is lacking. We focused here on two genes encoding the inward rectifier current, KCNJ2 and KCNJ12, in the dog heart. A combination of RT-PCR, 5'-RACE, and 3'-RACE demonstrated the status of KCNJ...

journal_title：Frontiers in physiology

authors： Houtman MJ,Takanari H,Kok BG,van Eck M,Montagne DR,Vos MA,de Boer TP,van der Heyden MA

更新日期：2012-01-30 00:00:00

abstract：:Development of mammalian teeth and surrounding tissues includes time-space changes in the extracellular matrix composition and organization. This requires complex control mechanisms to regulate its synthesis and remodeling. Fibril-associated collagens with interrupted triple helices (FACITs) and a group of small leuci...

journal_title：Frontiers in physiology

authors： Zvackova I,Matalova E,Lesot H

更新日期：2017-08-02 00:00:00

abstract：:Purpose: Few large-scale population-based studies have adequately examined the relationships between steroid hormones, health status and physical fitness. The purpose of the study was to describe the relationship of serum basal endogenous steroid hormones (testosterone, TES; empirical free testosterone, EFT; cortisol,...

journal_title：Frontiers in physiology

authors： Gagnon SS,Nindl BC,Vaara JP,Santtila M,Häkkinen K,Kyröläinen H

更新日期：2018-07-27 00:00:00

abstract：Context:Strength-endurance mainly depends on the power output, which is often expressed relative to the individual's maximal power capability (Pmax). However, an individual can develop the same power, but in different combinations of force and velocity (force-velocity condition). Also, at matched power output, changing...

journal_title：Frontiers in physiology

authors： Rivière JR,Peyrot N,Cross MR,Messonnier LA,Samozino P

更新日期：2020-10-09 00:00:00

abstract：:Hypertrophic cardiomyopathy (HCM) is the most common mendelian heart disease, with a prevalence of 1/500. HCM is a primary cause of sudden death, due to an heightened risk of ventricular tachyarrhythmias that often occur in young asymptomatic patients. HCM can slowly progress toward heart failure, either with preserve...

journal_title：Frontiers in physiology

authors： Coppini R,Ferrantini C,Mugelli A,Poggesi C,Cerbai E

更新日期：2018-10-16 00:00:00

abstract：:Alcoholic liver disease (ALD) encompasses hepatic steatosis, which may progress to alcoholic hepatitis, fibrosis, and cirrhosis. It remains a leading cause of morbidity and mortality in the US and worldwide. The severity of liver disease correlates with plasma levels of bacterial products in patients, and experimental...

journal_title：Frontiers in physiology

authors： Hartmann P,Chen WC,Schnabl B

更新日期：2012-10-11 00:00:00

abstract：:Neural crest (NC) cells are multipotent embryonic cells that form melanocytes, craniofacial bone and cartilage, and the peripheral nervous system in vertebrates. NC cells express many cadherin proteins, which control their specification, epithelial to mesenchymal transition (EMT), migration, and mesenchymal to epithel...

journal_title：Frontiers in physiology

authors： Manohar S,Camacho-Magallanes A,Echeverria C Jr,Rogers CD

更新日期：2020-10-30 00:00:00

abstract：:Gut microbiota has been reported to contribute to reduced diet-induced obesity upon cold exposure. Furthermore, gut microbiome fermentation determines the efficacy of exercise for diabetes prevention and enhances exercise performance. However, there have been no systematic examinations of changes in gut microbiome com...

journal_title：Frontiers in physiology

authors： Meng Y,Chen L,Lin W,Wang H,Xu G,Weng X

更新日期：2020-05-04 00:00:00

abstract：:The purpose of this study was to examine the effects of a short-term ketogenic diet (KD) on body composition and cardiorespiratory fitness (CRF) in overweight/obese Chinese females. Twenty young females [age: 21.0 ± 3.7 years, weight: 65.5 ± 7.7 kg, body mass index (BMI): 24.9 ± 2.7 kg⋅m-2] consumed 4 weeks of a norma...

journal_title：Frontiers in physiology

authors： Kong Z,Sun S,Shi Q,Zhang H,Tong TK,Nie J

更新日期：2020-07-28 00:00:00

abstract：:Long-duration spaceflight has been shown to negatively affect the lumbopelvic muscles of crewmembers. Through analysis of computed tomography scans of crewmembers on 4- to 6-month missions equipped with the interim resistive exercise device, the structural deterioration of the psoas, quadratus lumborum, and paraspinal...

journal_title：Frontiers in physiology

authors： McNamara KP,Greene KA,Moore AM,Lenchik L,Weaver AA

更新日期：2019-05-21 00:00:00

abstract：:The age at which women experience their first pregnancy has increased throughout the decades. Pregnancy has an important influence on maternal short- and long-term cardiovascular outcomes. Pregnancy at an advanced maternal age increases maternal risk of gestational diabetes, preeclampsia, placenta previa and caesarian...

journal_title：Frontiers in physiology

authors： Morton JS,Care AS,Kirschenman R,Cooke CL,Davidge ST

更新日期：2017-06-30 00:00:00

abstract：:Glutaraldehyde is a well-known substance used in biomedical research to fix cells. Since hemolytic anemias are often associated with red blood cell shape changes deviating from the biconcave disk shape, conservation of these shapes for imaging in general and 3D-imaging in particular, like confocal microscopy, scanning...

journal_title：Frontiers in physiology

authors： Abay A,Simionato G,Chachanidze R,Bogdanova A,Hertz L,Bianchi P,van den Akker E,von Lindern M,Leonetti M,Minetti G,Wagner C,Kaestner L

更新日期：2019-05-14 00:00:00

abstract：:The main goal of this study was to assess the impact of the cambered bar (CB) during the bench press exercise on power output and bar velocity when compared to a standard bar (SB). Ten healthy strength-trained men (age = 27.9 ± 3.7 years; body mass = 90.1 ± 12.5 kg; resistance training experience = 6.5 ± 2.7 years; be...

journal_title：Frontiers in physiology

authors： Krzysztofik M,Zajac A,Żmijewski P,Wilk M

更新日期：2020-10-20 00:00:00

abstract：:In addition to its roles in the maintenance of interstitial fluid homeostasis and immunosurveillance, the lymphatic system has a critical role in regulating transport of dietary lipids to the blood circulation. Recent work within the past two decades has identified an important relationship between lymphatic dysfuncti...

journal_title：Frontiers in physiology

authors： Norden PR,Kume T

更新日期：2020-05-05 00:00:00

abstract：:[This corrects the article DOI: 10.3389/fphys.2019.01574.]. ...

journal_title：Frontiers in physiology

authors： Figueroa VA,Jara O,Oliva CA,Ezquer M,Ezquer F,Retamal MA,Martínez AD,Altenberg GA,Vargas AA

更新日期：2020-02-11 00:00:00

abstract：:Endothelial cells have emerged as key players in SARS-CoV-2 infection and COVID-19 inflammatory pathologies. Dysfunctional endothelial cells can promote chronic inflammation and disease processes like thrombosis, atherosclerosis, and lung injury. In endothelial cells, mitochondria regulate these inflammatory pathways ...

journal_title：Frontiers in physiology

authors： Chang R,Mamun A,Dominic A,Le NT

更新日期：2021-01-15 00:00:00

abstract：:β1,3-N-acetylglucosaminyltransferase (β3GnT8) and β3GnT2 are key enzymes that catalyzes the formation of polylactosamine glycan structures by transferring GlcNAc to tetra-antennary β1-6-branched N-glycan and it also has an important effect on the progression of various types of human cancer. They have been reported to...

journal_title：Frontiers in physiology

authors： Jiang Z,Zhang H,Liu C,Yin J,Tong S,Lv J,Wei S,Wu S

更新日期：2018-05-23 00:00:00

abstract：:The cotton boll weevil, Anthonomus grandis, is the most economically important pest of cotton in Brazil. Pest management programs focused on A. grandis are based mostly on the use of chemical insecticides, which may cause serious ecological impacts. Furthermore, A. grandis has developed resistance to some insecticides...

journal_title：Frontiers in physiology

authors： Firmino AAP,Pinheiro DH,Moreira-Pinto CE,Antonino JD,Macedo LLP,Martins-de-Sa D,Arraes FBM,Coelho RR,Fonseca FCA,Silva MCM,Engler JA,Silva MS,Lourenço-Tessutti IT,Terra WR,Grossi-de-Sa MF

更新日期：2020-11-16 00:00:00

abstract：:Mature spermatozoa have highly condensed DNA that is essentially silent both transcriptionally and translationally. Therefore, post translational modifications are very important for regulating sperm motility, morphology, and for male fertility in general. Protein sumoylation was recently demonstrated in human and rod...

journal_title：Frontiers in physiology

authors： Brohi RD,Wang L,Hassine NB,Cao J,Talpur HS,Wu D,Huang CJ,Rehman ZU,Bhattarai D,Huo LJ

更新日期：2017-06-13 00:00:00

abstract：:We previously demonstrated that ureteral obstruction is associated with a urinary concentrating defect and reduced expression of renal aquaporins (AQPs), in which the renin-angiotensin system (RAS) may play an important role. The aims of the present study were to examine whether the renin inhibitor aliskiren could pre...

journal_title：Frontiers in physiology

authors： Hu S,Xie H,Luo R,Feng P,Liu Q,Han M,Kong Y,Zou X,Wang W,Li C

更新日期：2019-09-13 00:00:00

abstract：:Carbon monoxide (CO) that is produced in a number of different mammalian tissues is now known to have significant effects on the cardiovascular system. These include: (i) vasodilation, (ii) changes in heart rate and strength of contractions, and (iii) modulation of autonomic nervous system input to both the primary pa...

journal_title：Frontiers in physiology

authors： Trenor B,Cardona K,Saiz J,Rajamani S,Belardinelli L,Giles WR

更新日期：2013-10-17 00:00:00

abstract：:Tumor necrosis factor (TNF)-α, a major part in inflammatory, infectious and tumor processes, and is pivotal at the early stages of gastric cancer. Relationship between its risk and TNF-α rs361525 polymorphism has been demonstrated, but remains conflicting and controversial. Therefore, a meta-analysis was conducted to ...

journal_title：Frontiers in physiology

authors： Xu T,Kong Z,Zhao H

更新日期：2018-05-15 00:00:00

abstract：:The development of durable ventricular assist devices (VADs) has improved mortality rates and quality of life in patients with end stage heart failure. While the use of VADs has increased dramatically in recent years, there is limited experience with VAD implantation in patients with complex congenital heart disease (...

journal_title：Frontiers in physiology

authors： Villa CR,Morales DLS

更新日期：2017-05-09 00:00:00

abstract：:This study aimed to simultaneously examine the differences of human nerve conduction velocity (NCV) and nerve cross-sectional area (nCSA) between the upper and lower limbs and between different regions of the upper and lower limbs. Thirty healthy subjects volunteered for the study. NCV and nCSA of the ulnar and tibial...

journal_title：Frontiers in physiology

authors： Nobue A,Kunimasa Y,Tsuneishi H,Sano K,Oda H,Ishikawa M

更新日期：2020-12-03 00:00:00

abstract：:Periventricular-intraventricular hemorrhages (PIVH) and (diffuse) white matter injury (WMI) are the most important acquired brain lesions of the very and extremely prematurely born neonate. Both carry a high risk for death or adverse neurodevelopmental outcome. The first part of the review discusses the standard of ca...

journal_title：Frontiers in physiology

authors： van Bel F,Vaes J,Groenendaal F

更新日期：2019-03-20 00:00:00

abstract：:Cardiac arrest is a prevalent condition with a poor prognosis, attributable in part to persistent myocardial dysfunction following resuscitation. The molecular basis of this dysfunction remains unclear. We induced cardiac arrest in a porcine model of acute sudden death and assessed the impact of ischemia and reperfusi...

journal_title：Frontiers in physiology

authors： Woodward M,Previs MJ,Mader TJ,Debold EP

更新日期：2015-07-16 00:00:00