Diagnostic accuracy of genetic markers and nucleic acid techniques for the detection of Leptospira in clinical samples: A meta-analysis.

abstract：OBJECTIVE:The aim of the study is to examine the spatiotemporal pattern of Japanese Encephalitis (JE) in mainland China during 2002-2010. Specific objectives of the study were to quantify the temporal variation in incidence of JE cases, to determine if clustering of JE cases exists, to detect high risk spatiotemporal c...

journal_title：PLoS neglected tropical diseases

authors： Wang LY,Zhang WY,Ding F,Hu WB,Soares Magalhaes RJ,Sun HL,Li YX,Zou W,Wang Y,Liu QY,Li SL,Yin WW,Huang LY,Clements AC,Bi P,Li CY

更新日期：2013-06-20 00:00:00

abstract：:Trypanosoma cruzi, the aetiological agent of Chagas disease possess extensive genetic diversity. This has led to the development of a plethora of molecular typing methods for the identification of both the known major genetic lineages and for more fine scale characterization of different multilocus genotypes within th...

journal_title：PLoS neglected tropical diseases

authors： Diosque P,Tomasini N,Lauthier JJ,Messenger LA,Monje Rumi MM,Ragone PG,Alberti-D'Amato AM,Pérez Brandán C,Barnabé C,Tibayrenc M,Lewis MD,Llewellyn MS,Miles MA,Yeo M

更新日期：2014-08-28 00:00:00

abstract：:To eliminate schistosomiasis, appropriate diagnostic tests are required to monitor its prevalence and transmission, especially in the settings with low endemicity resulting from the consecutive mass drug administration. Antibodies that react with either crude soluble schistosome egg antigens or soluble worm antigen pr...

journal_title：PLoS neglected tropical diseases

authors： Mohammed ES,Nakamura R,Kalenda YD,Deloer S,Moriyasu T,Tanaka M,Fujii Y,Kaneko S,Hirayama K,Ibrahim AI,El-Seify MA,Metwally AM,Hamano S

更新日期：2020-09-11 00:00:00

abstract：:Tsetse are vectors of pathogenic trypanosomes, agents of human and animal trypanosomiasis in Africa. Components of tsetse saliva (sialome) are introduced into the mammalian host bite site during the blood feeding process and are important for tsetse's ability to feed efficiently, but can also influence disease transmi...

journal_title：PLoS neglected tropical diseases

authors： Zhao X,Alves e Silva TL,Cronin L,Savage AF,O'Neill M,Nerima B,Okedi LM,Aksoy S

更新日期：2015-08-27 00:00:00

abstract：:Diagnosis of a first-time visceral leishmaniasis (VL) infection in Ethiopia is established by use of a rapid diagnostic test (RDT) detecting antibodies against rK39, direct agglutination test (DAT) and microscopy according to the national algorithm. The performance of individual tests and algorithm is variable and dep...

journal_title：PLoS neglected tropical diseases

authors： Kassa M,Abdellati S,Cnops L,Bremer Hinckel BC,Yeshanew A,Hailemichael W,Vogt F,Adriaensen W,Mertens P,Diro E,van Griensven J,Van den Bossche D

更新日期：2020-12-31 00:00:00

abstract：BACKGROUND:Arboviruses have overlapping geographical distributions and can cause symptoms that coincide with more common infections. Therefore, arbovirus infections are often neglected by travel diagnostics. Here, we assessed the potential of syndrome-based approaches for diagnosis and surveillance of neglected arbovir...

journal_title：PLoS neglected tropical diseases

authors： Cleton NB,Reusken CB,Wagenaar JF,van der Vaart EE,Reimerink J,van der Eijk AA,Koopmans MP

更新日期：2015-09-15 00:00:00

abstract：:The new world arenavirus Junín virus (JUNV) is the causative agent of Argentine hemorrhagic fever, a lethal human infectious disease. Adult laboratory mice are generally resistant to peripheral infection by JUNV. The mechanism underlying the mouse resistance to JUNV infection is largely unknown. We have reported that ...

journal_title：PLoS neglected tropical diseases

authors： Huang C,Walker AG,Grant AM,Kolokoltsova OA,Yun NE,Seregin AV,Paessler S

更新日期：2014-06-05 00:00:00

abstract：:Eumycetoma (mycotic mycetoma) is the fungal form of mycetoma, a subcutaneous infection occurring in individuals living in endemic areas of the disease. The Sudan is hyperendemic for mycetoma, with the highest incidence being reported from Gezira State, Central Sudan. The present study was conducted at the Gezira Mycet...

journal_title：PLoS neglected tropical diseases

authors： Ahmed EA,Nour BYM,Abakar AD,Hamid S,Mohamadani AA,Daffalla M,Mahmoud M,Altayb HN,Desnos-Ollivier M,de Hoog S,Ahmed SA

更新日期：2020-07-30 00:00:00

abstract：:The interaction between Plasmodium vivax Duffy binding protein (PvDBP) and Duffy antigen receptor for chemokines (DARC) has been described as critical for the invasion of human reticulocytes, although increasing reports of P. vivax infections in Duffy-negative individuals questions its unique role. To investigate the ...

journal_title：PLoS neglected tropical diseases

authors： Roesch C,Popovici J,Bin S,Run V,Kim S,Ramboarina S,Rakotomalala E,Rakotoarison RL,Rasoloharimanana T,Andriamanantena Z,Kumar A,Guillotte-Blisnick M,Huon C,Serre D,Chitnis CE,Vigan-Womas I,Menard D

更新日期：2018-10-22 00:00:00

abstract：BACKGROUND:Bithynia siamensis goniomphalos is the snail intermediate host of the liver fluke, Opisthorchis viverrini, the leading cause of cholangiocarcinoma (CCA) in the Greater Mekong sub-region of Thailand. Despite the severe public health impact of Opisthorchis-induced CCA, knowledge of the molecular interactions o...

journal_title：PLoS neglected tropical diseases

authors： Prasopdee S,Sotillo J,Tesana S,Laha T,Kulsantiwong J,Nolan MJ,Loukas A,Cantacessi C

更新日期：2014-03-27 00:00:00

abstract：:Clonorchiasis is one of the most important food-borne trematodiases affecting millions of people. Strategies were recommended by different organizations and control programmes were implemented but mostly in short-time periods. It's important to assess the long-term benefits and sustainability of possible control strat...

journal_title：PLoS neglected tropical diseases

authors： Huang XH,Qian MB,Zhu GH,Fang YY,Hao YT,Lai YS

更新日期：2020-03-27 00:00:00

abstract：:Over two-thirds of the world's population lives in regions where rabies is endemic, resulting in over 15 million people receiving multi-dose post-exposure prophylaxis (PEP) and over 55,000 deaths per year globally. A major goal in rabies virus (RABV) research is to develop a single-dose PEP that would simplify vaccina...

journal_title：PLoS neglected tropical diseases

authors： Dorfmeier CL,Tzvetkov EP,Gatt A,McGettigan JP

更新日期：2013-01-01 00:00:00

abstract：:A 51-year-old man with 3-month unhealing cat bite wound was diagnosed with sporotrichosis, a subacute-to-chronic infection caused by the worldwide endemic, dimorphic fungus Sporothrix globosa. The case would help clinicians to raise awareness of human sporotrichosis due to cat bites, which remains rare and is likely t...

journal_title：PLoS neglected tropical diseases

authors： Liu Y,Liu L,Kang M,Zong Z

更新日期：2020-12-03 00:00:00

abstract：BACKGROUND:Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS) has recently emerged in the field of entomology as a promising method for the identification of arthropods and the detection of associated pathogens. METHODOLOGY/PRINCIPAL FINDINGS:An experimental model of Ctenocepha...

journal_title：PLoS neglected tropical diseases

authors： El Hamzaoui B,Laroche M,Almeras L,Bérenger JM,Raoult D,Parola P

更新日期：2018-02-16 00:00:00

abstract：BACKGROUND:Lymphatic filariasis (LF) is a so-called neglected tropical disease, currently overshadowed by higher-profile efforts to address malaria, tuberculosis, and HIV/AIDS. Despite recent successes in arresting transmission, some 40 million people who already have the disease have been largely neglected. This study...

journal_title：PLoS neglected tropical diseases

authors： Perera M,Whitehead M,Molyneux D,Weerasooriya M,Gunatilleke G

更新日期：2007-11-21 00:00:00

abstract：:Our knowledge and control of the pathogenesis induced by the filariae remain limited due to experimental obstacles presented by parasitic nematode biology and the lack of selective prophylactic or curative drugs. Here we thought to investigate the role of neutrophils in the host innate immune response to the infection...

journal_title：PLoS neglected tropical diseases

authors： Pionnier N,Brotin E,Karadjian G,Hemon P,Gaudin-Nomé F,Vallarino-Lhermitte N,Nieguitsila A,Fercoq F,Aknin ML,Marin-Esteban V,Chollet-Martin S,Schlecht-Louf G,Bachelerie F,Martin C

更新日期：2016-04-25 00:00:00

abstract：:Orientia tsutsugamushi (Ots) frequently causes severe scrub typhus infections in the Asia-Pacific region. Korean investigators have demonstrated that Ots encodes five different autotransporter domain (ATD) proteins (ScaA-ScaE). ScaA functions as an adhesin and confers protective immunity in a lethal mouse model of Ots...

journal_title：PLoS neglected tropical diseases

authors： Koralur MC,Ramaiah A,Dasch GA

更新日期：2018-09-20 00:00:00

abstract：BACKGROUND:Marburg virus (MARV), a zoonotic pathogen causing severe hemorrhagic fever in man, has emerged in Angola resulting in the largest outbreak of Marburg hemorrhagic fever (MHF) with the highest case fatality rate to date. METHODOLOGY/PRINCIPAL FINDINGS:A mobile laboratory unit (MLU) was deployed as part of the...

journal_title：PLoS neglected tropical diseases

authors： Grolla A,Jones SM,Fernando L,Strong JE,Ströher U,Möller P,Paweska JT,Burt F,Pablo Palma P,Sprecher A,Formenty P,Roth C,Feldmann H

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Socioeconomically deprived children are at increased risk of ill-health associated with sedentary behavior, malnutrition, and helminth infection. The resulting reduced physical fitness, growth retardation, and impaired cognitive abilities may impede children's capacity to pay attention. The present study exa...

journal_title：PLoS neglected tropical diseases

authors： Gall S,Müller I,Walter C,Seelig H,Steenkamp L,Pühse U,du Randt R,Smith D,Adams L,Nqweniso S,Yap P,Ludyga S,Steinmann P,Utzinger J,Gerber M

更新日期：2017-05-08 00:00:00

abstract：BACKGROUND:Primary infection of Toxoplasma gondii during pregnancy can be transmitted to the unborn child and may have serious consequences, including retinochoroiditis, hydrocephaly, cerebral calcifications, encephalitis, splenomegaly, hearing loss, blindness, and death. Austria, a country with moderate seroprevalence...

journal_title：PLoS neglected tropical diseases

authors： Prusa AR,Kasper DC,Sawers L,Walter E,Hayde M,Stillwaggon E

更新日期：2017-07-10 00:00:00

abstract：BACKGROUND:Nifurtimox eflornithine combination therapy (NECT) to treat human African trypanosomiasis (HAT), commonly called sleeping sickness, was added to the World Health Organisation's (WHO) Essential Medicines List in 2009 and to the Paediatric List in 2012. NECT was further tested and documented in a phase IIIb cl...

journal_title：PLoS neglected tropical diseases

authors： Kuemmerle A,Schmid C,Kande V,Mutombo W,Ilunga M,Lumpungu I,Mutanda S,Nganzobo P,Ngolo D,Kisala M,Valverde Mordt O

更新日期：2020-01-27 00:00:00

abstract：BACKGROUND:Trichinellosis is a serious zoonositc parasitosis worldwide. Because its clinical manifestations aren't specific, the diagnosis of trichinellosis is not easy to be made. Trichinella spiralis muscle larva (ML) excretory-secretory (ES) antigens are the most widely applied diagnostic antigens for human trichine...

journal_title：PLoS neglected tropical diseases

authors： Sun GG,Song YY,Jiang P,Ren HN,Yan SW,Han Y,Liu RD,Zhang X,Wang ZQ,Cui J

更新日期：2018-05-14 00:00:00

abstract：:One of the stated goals of the London Declaration on Neglected Tropical Diseases is the interruption of domiciliary transmissions of Chagas disease in the region of the Americas. We used a game-theoretic approach to assess the voluntary use of insecticide treated nets (ITNs) in the prevention of the spread of infectio...

journal_title：PLoS neglected tropical diseases

authors： Han CY,Issa H,Rychtář J,Taylor D,Umana N

更新日期：2020-11-03 00:00:00

abstract：BACKGROUND:The neglected tropical disease Buruli ulcer (BU) caused by Mycobacterium ulcerans is an infection of the subcutaneous tissue leading to chronic ulcerative skin lesions. Histopathological features are progressive tissue necrosis, extracellular clusters of acid fast bacilli (AFB) and poor inflammatory response...

journal_title：PLoS neglected tropical diseases

authors： Ruf MT,Chauty A,Adeye A,Ardant MF,Koussemou H,Johnson RC,Pluschke G

更新日期：2011-08-01 00:00:00

abstract：INTRODUCTION:Most of the studies related to rickettsial infection in Colombia are cross-sectional because of the challenge in conducting prospective studies on infectious disease that may have a difficult diagnosis. Although cross-sectional studies are essential to detect people exposed to rickettsiae, they are not sui...

journal_title：PLoS neglected tropical diseases

authors： Quintero Vélez JC,Aguirre-Acevedo DC,Rodas JD,Arboleda M,Troyo A,Vega Aguilar F,Osorio Quintero L,Rojas Arbeláez C

更新日期：2018-10-31 00:00:00

abstract：BACKGROUND:Chlamydia trachomatis is the etiological agent of trachoma the world's leading cause of infectious blindness. Here, we investigate whether protracted clearance of a primary infection in nonhuman primates is attributable to antigenic variation or related to the maturation of the anti-chlamydial humoral immune...

journal_title：PLoS neglected tropical diseases

authors： Kari L,Bakios LE,Goheen MM,Bess LN,Watkins HS,Southern TR,Song L,Whitmire WM,Olivares-Zavaleta N,Caldwell HD

更新日期：2013-05-30 00:00:00

abstract：:Rift Valley fever (RVF), a mosquito-borne zoonosis, is a major public health and veterinary problem in sub-Saharan Africa. Surveillance to monitor mosquito populations during the inter-epidemic period (IEP) and viral activity in these vectors is critical to informing public health decisions for early warning and contr...

journal_title：PLoS neglected tropical diseases

authors： Tchouassi DP,Sang R,Sole CL,Bastos AD,Teal PE,Borgemeister C,Torto B

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:There are health risks associated with wastewater and fecal sludge management and use, but little is known about the magnitude, particularly in rapidly growing urban settings of low- and middle-income countries. We assessed the point-prevalence and risk factors of intestinal parasite infections in people wit...

journal_title：PLoS neglected tropical diseases

authors： Fuhrimann S,Winkler MS,Kabatereine NB,Tukahebwa EM,Halage AA,Rutebemberwa E,Medlicott K,Schindler C,Utzinger J,Cissé G

更新日期：2016-03-03 00:00:00

abstract：BACKGROUND:Buruli ulcer (BU) is a chronic necrotizing infectious skin disease caused by Mycobacterium ulcerans. The treatment with BU-specific antibiotics is initiated after clinical suspicion based on the WHO clinical and epidemiological criteria. This study aimed to estimate the predictive values of these criteria an...

journal_title：PLoS neglected tropical diseases

authors： Ayelo GA,Sopoh GE,Houezo JG,Fiodessihoue R,Affolabi D,Dossou AD,Barogui YT,Wadagni AAC,Agossadou DC,Hasker E,Portaels F,de Jong BC,Eddyani M

更新日期：2018-08-06 00:00:00

abstract：BACKGROUND:China has the highest incidence of hemorrhagic fever with renal syndrome (HFRS) worldwide. Reported cases account for 90% of the total number of global cases. By 2010, approximately 1.4 million HFRS cases had been reported in China. This study aimed to explore the effect of the rodent reservoir, and natural ...

journal_title：PLoS neglected tropical diseases

authors： Xiao H,Tian HY,Gao LD,Liu HN,Duan LS,Basta N,Cazelles B,Li XJ,Lin XL,Wu HW,Chen BY,Yang HS,Xu B,Grenfell B

更新日期：2014-01-09 00:00:00