Abstract:
INTRODUCTION:This study was initiated to investigate the risk factors of secondary infections in febrile neutropenic patients following chemotherapy, and to evaluate the clinical, microbiological, and mortality outcomes of these infections. METHODOLOGY:An evaluation was done on all patients with hematological malignancy who developed a febrile neutropenic episode (FNE) after cytotoxic chemotherapy in the Department of Hematology, Akdeniz University Faculty of Medicine, between January 2007 and December 2008. RESULTS:A total of 294 primary FNEs that responded to the initial empirical or targeted treatment were included in the study, and secondary infections developed after 72 (24.5%) of 294 primary FNEs. Risk factors for secondary infections were determined as acute leukemia as the underlying disease, salvage chemotherapy for refractory/relapse diseases, prolonged neutropenia (10 days and over), Multinational Association of Supportive Care in Cancer (MASSC) score < 21, and fungal infection during the primary episode. The mortality rate of patients who developed secondary infections was significantly higher compared to patients without secondary infections (27.8% and 5.4%, respectively; p = 0.001). CONCLUSIONS:The development of secondary infections in patients with hematological malignancy was not very rare. Greater concern should be shown for these infections to increase patient survival rates.
journal_name
J Infect Dev Ctriesjournal_title
Journal of infection in developing countriesauthors
Büyüktuna SA,Saba R,Gözel MG,Turhan Ö,İnan D,Aşık Z,Köse Adoi
10.3855/jidc.8530subject
Has Abstractpub_date
2017-07-31 00:00:00pages
521-526issue
7eissn
2036-6590issn
1972-2680journal_volume
11pub_type
杂志文章abstract:INTRODUCTION:Leptospirosis is a zoonotic disease caused by the spirochete of genus Leptospira with widespread distribution in tropical, subtropical and temperate zones. Leptospirosis is often confused with other febrile illnesses including jaundice, dengue, and malaria. Generally, the disease is often underdiagnosed or...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.9545
更新日期:2018-01-31 00:00:00
abstract:INTRODUCTION:Hepatitis E is considered an emerging human viral disease with many evidences of zoonotic nature of disease, and swine are the main reservoir of HEV. The aim of this study was to determine HEV seroprevalence in commercial pig farms, backyard pigs, slaughtered pigs and wild boars in the region of the city B...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.12552
更新日期:2020-06-30 00:00:00
abstract::A novel influenza A H1N1 virus of swine origin is responsible for the influenza epidemic affecting Mexico, the United States of America (USA), and 39 other countries. While the origin of this emerging pathogen remains uncertain, an increase in the reported incidence of respiratory diseases was noted during March 2009 ...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章,评审
doi:10.3855/jidc.238
更新日期:2009-06-01 00:00:00
abstract:INTRODUCTION:In some developing countries, tuberculosis and brucellosis, which are commom causes of spinal infections, are still common infectious diseases. However, co-occurrence of spinal tuberculosis and brucellosis is rare. METHODOLOGY:We report a case a 47-year-old male engaged in aquaculture with a medical histo...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.12647
更新日期:2020-10-31 00:00:00
abstract:INTRODUCTION:This study was aimed to determine the relationship between vitamin D and soluble vitamin D receptor (VDR) levels and brucellosis, a common infection in Turkey, in which the cellular immune system is important in the course of the disease. METHODOLOGY:Patients who had been followed up in the Department of ...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.5675
更新日期:2016-02-28 00:00:00
abstract:INTRODUCTION:Hepatitis B infection is a serious global public health problem. The aim of the study was to assess the seroprevalance of hepatitis B surface antigen (HBsAg), as well as the risk factors associated with hepatitis B virus (HBV) infection among pregnant women attending antenatal care clinics of the Universit...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.10018
更新日期:2018-10-31 00:00:00
abstract:INTRODUCTION:Dengue virus (DENV) infection is currently a major cause of morbidity in the world, and its incidence has mainly increased during the last years in Latin America, including Paraguay. The objective of this study was to compare the clinical and laboratory findings of dengue and assess whether the serotype is...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.11584
更新日期:2019-12-31 00:00:00
abstract:INTRODUCTION:There is limited knowledge about the associations of Helicobacter pylori (H. pylori) infections in developing countries. This study aimed to determine the current prevalence and associations of H. pylori infection with breastfeeding practices, nutritional status, and recurrent abdominal pain (RAP) in a gro...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.3196
更新日期:2014-04-15 00:00:00
abstract:INTRODUCTION:Salmonella infections are increasing worldwide, but there are few reports on Salmonella surveillance in African countries and other developing countries. This has made it difficult to estimate the actual burden of salmonellosis, especially in Africa. This study was conducted in a neglected Northern Region ...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.3548
更新日期:2013-10-15 00:00:00
abstract:INTRODUCTION:The aim of this study was to asses the surveillance of influenza A/other respiratory viruses and risk factors in hospitalized children with the symptoms of influenza-like illness during two consecutive influenza seasons. METHODOLOGY:All children hospitalized with adiagnosis of influenza-like illness had b...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.8867
更新日期:2018-01-10 00:00:00
abstract:BACKGROUND:Expansion of the health care workforce in Peru to combat tuberculosis (TB) includes both professional health care providers (HCPs) such as doctors and nurses, and non-professional HCPs such as community health workers (CHWs). We describe the knowledge and attitudes of these HCPs, and identify modifiable barr...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.335
更新日期:2009-12-15 00:00:00
abstract::Madura foot is a deep mycosis commonly seen in tropical and subtropical countries such as India. Its incidence is likely to rise in temperate regions as well, due to the increase in worldwide travel. The cases presented here are all agricultural workers from a rural part of northern India who had induration, fibrosis ...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.2387
更新日期:2012-09-17 00:00:00
abstract:INTRODUCTION:Hand, foot, and mouth disease (HFMD) is a common childhood illness caused by enteroviruses. A passive surveillance system has been implemented in Shanghai Pudong since 2008 and etiology surveillance since 2009.We characterized the epidemiology and the etiology of HFMD in Pudong from 2008-2013. METHODOLOGY...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.6118
更新日期:2016-06-30 00:00:00
abstract:INTRODUCTION:The current cohort study was conducted to determine the frequency and compare the mortality rate with associated characteristics among low birth weight and normal birth weight infants during the neonatal period at a tertiary healthcare facility, Karachi. METHODOLOGY:Close-ended structured questionnaires w...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.3569
更新日期:2014-09-13 00:00:00
abstract:INTRODUCTION:Inadequate hand-washing facilities have been reported as a barrier to hand washing. This study aimed to evaluate the availability and accessibility of hand-washing facilities and supplies of hand-washing agents in the outpatient department (OPD) complex of a tertiary care teaching hospital. METHODOLOGY:A ...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.1003
更新日期:2011-03-02 00:00:00
abstract::Coronavirus disease 2019 (COVID-19) represents a severe global public health threat. Caused by SARS-Cov-2, COVID-19 is characterized by high transmission rate that correlates with high viral load. The full clinical spectrum of the illness, the prevalence rates of mild symptomatic and asymptomatic cases, and the case f...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章,评审
doi:10.3855/jidc.12805
更新日期:2020-09-30 00:00:00
abstract:INTRODUCTION:Uropathogenic Escherichia coli (UPEC) are the main etiological agent of urinary tract infections (UTIs). Association between different serotypes and UTIs is known, however, some strains are incapable to be serotyped. The aim of this work was to study bthe phenotypical and genotypical characteristics of 113...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.11098
更新日期:2019-06-30 00:00:00
abstract:BACKGROUND:This work demonstrates successful propagation of HCV in HepG2 and human blood cells as well as viral shedding into their culture media. The influence of Schistosoma mansoni crude soluble egg antigens (SEA) on the rate of viral propagation in both mammalian cells was also monitored. METHODOLOGY:HepG2 cells w...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.522
更新日期:2010-05-01 00:00:00
abstract:INTRODUCTION:Staphylococcal colonization is a risk factor for healthcare-associated infections, which are frequent in Neonatal Intensive Care Units (NICU). This study analyzed microbiology, epidemiology and clinical aspects of Staphylococcus spp. colonizing neonates. METHODOLOGY:Nasal or periumbilical swabs were evalu...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.11241
更新日期:2019-09-30 00:00:00
abstract:INTRODUCTION:The novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the coronavirus disease 2019 (COVID-19). First COVID-19 case was detected in March, 10, 2020 in Turkey and as of May, 18, 2020 148,067 cases have been identified and 4096 citizens have died. Tuberculosis (...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.13152
更新日期:2020-07-31 00:00:00
abstract:INTRODUCTION:Brucellosis is a multisystemic infectious disease, which can manifest as endocarditis. Diagnosis can be challenging. CASE PRESENTATION:An 80-year-old male patient presented with fever 38.5 °C, cough and progressive shortness of breath of 14 days. History of Brucellosis 18 months earlier inadequately treat...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.10186
更新日期:2018-02-22 00:00:00
abstract:INTRODUCTION:Schistosomiasis is one of the Neglected Tropical Diseases in Ethiopia. Since 2015, yearly school-based mass drug administration (MDA) using praziquantel has become the major control strategy. This study aimed to assess trends of Schistosoma mansoni infection in a high-endemic area in Northwest Ethiopia. M...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.11727
更新日期:2020-06-29 00:00:00
abstract:INTRODUCTION:Saudi Arabia (SA) experienced a highly pathogenic avian influenza (HPAI) H5N1 outbreak in domesticated birds in 2007. METHODOLOGY:Forty-three hemagglutinin (HA) and 41 neuraminidase (NA) genes of HPAI H5N1 viruses were sequenced and phylogenetic analyses of completely sequenced genes were performed to com...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.6546
更新日期:2015-11-30 00:00:00
abstract:INTRODUCTION:Coronary heart disease and its risk factors depend on genetic characteristics, behaviors, and habits, all of which vary in different regions. The use of antiretroviral therapy (ARV) has increased the survival of people living with HIV/AIDS (PLWHA), who begin to present mortality indicators similar to the g...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.5867
更新日期:2015-09-27 00:00:00
abstract:INTRODUCTION:The present study was conducted to evaluate the prevalence of Trichuris spp. and other intestinal parasitic infections in owned cats on St. Kitts. METHODOLOGY:The feces of 41 non-feral cats (23 indoor only; 18 indoor/outdoor) were examined for the presence of Trichuris spp. eggs. RESULTS:Nine (22%) of th...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.5778
更新日期:2015-01-15 00:00:00
abstract:INTRODUCTION:Helicobacter pylori is a principal cause of gastric cancer. The aim of this study was to determine the prevalence and contribution of duodenal ulcer promoting gene A (dupA), the plasticity region genes and sigma factors in relation to their pathological expression of H. pylori infections in the Nigerian po...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.11746
更新日期:2020-02-29 00:00:00
abstract:BACKGROUND:The treatment of methicillin-resistant staphylococcal infections has been a growing problem both in and out of hospitals for the past 30 years. Therefore, there is a need for other antibiotics as an alternative to glycopeptides in the treatment of methicillin-resistant staphylococcal infections. This study i...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.3867
更新日期:2013-11-15 00:00:00
abstract:INTRODUCTION:Salmonella enterica serotype Kentucky was isolated from septic poultry in Nigeria. The objective of this study was to characterize this isolate by screening for SGI1 and hyper-virulence. METHODOLOGY:The strain was characterized by identification of Salmonella genomic island 1 (SGI1) through a PCR assay an...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.1988
更新日期:2012-06-15 00:00:00
abstract:INTRODUCTION:Salmonella enterica subspecies enterica serovar Choleraesuis is a host-adapted, facultative, intracellular pathogen that causes swine paratyphoid. Its antimicrobial resistance presents a challenge to feed manufacturing industries. However, stopping antibiotics in animal feed would have economic implication...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.3861
更新日期:2014-11-13 00:00:00
abstract:INTRODUCTION:Ice can be contaminated by pathogenic bacteria. This study aimed to identify critical points in iced beverage production and distribution lines to examine the presence of pathogenic bacteria in a beverage and its processing environment, as well as when water and ice used as main ingredients. METHODOLOGY:T...
journal_title:Journal of infection in developing countries
pub_type: 杂志文章
doi:10.3855/jidc.8934
更新日期:2017-06-30 00:00:00