Long-Term Effects of Traumatic Brain Injury on Anxiety-Like Behaviors in Mice: Behavioral and Neural Correlates.

abstract：:PAOPA, a potent analog of prolyl-leucyl-glycinamide, has shown therapeutic potential at the preclinical stage for dopaminergic related illnesses, including animal models of schizophrenia, Parkinson's disease and haloperidol-induced extrapyramidal movement disorders. PAOPA's unique allosteric mechanism and dopamine D2 ...

journal_title：Frontiers in behavioral neuroscience

authors： Daya RP,Bhandari J,Kooner SK,Ho J,Rowley CD,Bock NA,Farncombe T,Mishra RK

更新日期：2018-12-12 00:00:00

abstract：:Huntington's Disease (HD) is a progressive neurodegenerative disorder that causes motor, cognitive, and psychiatric symptoms. In these experiments, we tested if operant training at an early age affected adult cognitive deficits in the zQ175 KI Het (zQ175) mouse model of HD. In Experiment 1 we trained zQ175 mice in a f...

journal_title：Frontiers in behavioral neuroscience

authors： Curtin PC,Farrar AM,Oakeshott S,Sutphen J,Berger J,Mazzella M,Cox K,He D,Alosio W,Park LC,Howland D,Brunner D

更新日期：2016-01-11 00:00:00

abstract：:The dopaminergic system is known to be involved in working memory processed by several brain regions like prefrontal cortex (PFC), hippocampus, striatum. In an earlier study we could show that Levodopa but not Modafinil enhanced working memory in a T-maze only during the early phase of training (day 3), whereas the la...

journal_title：Frontiers in behavioral neuroscience

authors： Bezu M,Maliković J,Kristofova M,Engidawork E,Höger H,Lubec G,Korz V

更新日期：2017-10-13 00:00:00

abstract：:Extensive evidence indicates that glucocorticoid hormones act in a variety of brain regions to enhance the consolidation of memory of emotionally motivated training experiences. We previously reported that corticosterone, the major glucocorticoid in the rat, administered into the dorsal striatum immediately after inhi...

journal_title：Frontiers in behavioral neuroscience

authors： Sánchez-Resendis O,Medina AC,Serafín N,Prado-Alcalá RA,Roozendaal B,Quirarte GL

更新日期：2012-06-22 00:00:00

abstract：:Inflammatory bowel disease is associated with an increased risk of mental disorders and can be exacerbated by stress. In this study which was performed with male 10-week old C57Bl/6N mice, we used dextran sulfate sodium (DSS)-induced colitis to evaluate behavioral changes caused by intestinal inflammation, to assess t...

journal_title：Frontiers in behavioral neuroscience

authors： Hassan AM,Jain P,Reichmann F,Mayerhofer R,Farzi A,Schuligoi R,Holzer P

更新日期：2014-11-06 00:00:00

abstract：:It is suggested that striatal cAMP responsive element binding protein (CREB) regulates sensitivity to psychostimulants. To test the cell-specificity of this hypothesis we examined the effects of a dominant-negative CREB protein variant expressed in dopamine receptor D1 (D1R) neurons on cocaine-induced behaviors. A tra...

journal_title：Frontiers in behavioral neuroscience

authors： Bilbao A,Rieker C,Cannella N,Parlato R,Golda S,Piechota M,Korostynski M,Engblom D,Przewlocki R,Schütz G,Spanagel R,Parkitna JR

更新日期：2014-06-11 00:00:00

abstract：:We sought to validate the psychometric properties of a recently developed paradigm that aims to measure salience attribution processes proposed to contribute to positive psychotic symptoms, the Salience Attribution Test (SAT). The "aberrant salience" measure from the SAT showed good face validity in previous results, ...

journal_title：Frontiers in behavioral neuroscience

authors： Schmidt K,Roiser JP

更新日期：2009-12-23 00:00:00

abstract：:The question of how individual differences related to self-regulation interact with alcohol use patterns to predict intimate partner aggression (IPA) is examined. We hypothesized that excessive drinking will be related to partner aggression among those who have low self-regulation. In addition, we explored the extent ...

journal_title：Frontiers in behavioral neuroscience

authors： Quigley BM,Levitt A,Derrick JL,Testa M,Houston RJ,Leonard KE

更新日期：2018-07-05 00:00:00

abstract：:The eye's pupil undergoes dynamic changes in diameter associated with cognitive effort, motor activity and emotional state, and can be used to index brain state across mammalian species. Recent studies in head-fixed mice have linked arousal-related pupil dynamics with global neural activity as well as the activity of ...

journal_title：Frontiers in behavioral neuroscience

authors： Lee CR,Margolis DJ

更新日期：2016-11-01 00:00:00

abstract：:Anesthetics are often used to characterize the activity of single neurons in vivo for their advantages such as reduction of noise level and convenience in noxious stimulations. Urethane has been a widely used anesthetic in thalamic studies under the assumption that sensory signals are still relayed to the thalamus und...

journal_title：Frontiers in behavioral neuroscience

authors： Huh Y,Cho J

更新日期：2013-10-10 00:00:00

abstract：:The new-released Diagnostic and Statistical Manual of Mental Disorders (DSM-5) defines post-traumatic stress disorder (PTSD) as a "trauma and stressor-related disorder". PTSD pathogenesis relies on paradoxical changes of emotional memory processing induced by the trauma exposure and associated with emotional dysfuncti...

journal_title：Frontiers in behavioral neuroscience

authors： Berardi A,Trezza V,Palmery M,Trabace L,Cuomo V,Campolongo P

更新日期：2014-04-29 00:00:00

abstract：:Reconsolidation is the post-retrieval stabilization of memories, a time-limited process during which reactivated (i.e., retrieved) memories can be updated with new information, become stronger or weaker, depending on the specific treatment. We have previously shown that the stress hormone cortisol has an enhancing eff...

journal_title：Frontiers in behavioral neuroscience

authors： Meir Drexler S,Merz CJ,Lissek S,Tegenthoff M,Wolf OT

更新日期：2019-11-12 00:00:00

abstract：:There is conflicting evidence regarding whether calcium-permeable receptors are removed during group I mGluR-mediated synaptic depression. In support of this hypothesis, AMPAR rectification, a correlative index of the synaptic expression of GluA2-lacking calcium-permeable AMPARs (CP-AMPARs), is known to decrease after...

journal_title：Frontiers in behavioral neuroscience

authors： Park K,Song S,Hong I,Song B,Kim J,Park S,Lee J,Song S,An B,Kim J,Lee CJ,Shin KS,Choi S,Lee S

更新日期：2014-08-08 00:00:00

abstract：:Identifying the biological substrates of complex neurobehavioral traits such as alcohol dependency pose a tremendous challenge given the diverse model systems and phenotypic assessments used. To address this problem we have developed a platform for integrated analysis of high-throughput or genome-wide functional genom...

journal_title：Frontiers in behavioral neuroscience

authors： Bubier JA,Wilcox TD,Jay JJ,Langston MA,Baker EJ,Chesler EJ

更新日期：2016-01-21 00:00:00

abstract：:Parietal cortex and adjacent parts of the temporal cortex have recently been associated with bodily self-consciousness (BSC). Similarly, growing evidence suggests that the lateral parietal cortex is crucial for the subjective aspects of episodic autobiographical memory (EAM), which is based on the conscious experience...

journal_title：Frontiers in behavioral neuroscience

authors： Bréchet L,Grivaz P,Gauthier B,Blanke O

更新日期：2018-11-14 00:00:00

abstract：:We performed whole-cell recordings from basal forebrain (BF) cholinergic neurons in transgenic mice expressing enhanced green fluorescent protein (eGFP) under the control of the choline acetyltransferase promoter. BF cholinergic neurons can be differentiated into two electrophysiologically identifiable subtypes: early...

journal_title：Frontiers in behavioral neuroscience

authors： Unal CT,Golowasch JP,Zaborszky L

更新日期：2012-05-08 00:00:00

abstract：:Evidence regarding the association between early drinking (ED) and later dependence is controversial. It has been alternately hypothesized that ED either plays a causal role in the development of dependence or that it is an early marker of increased psychosocial vulnerabilities. Despite a clear rationale for delaying ...

journal_title：Frontiers in behavioral neuroscience

authors： Conde K,Peltzer RI,Gimenez PV,Cremonte M

更新日期：2020-03-05 00:00:00

abstract：:Stress disturbs the balance of the gut microbiota and stimulates inflammation-to-brain mechanisms. Moreover, stress leads to anxiety and depressive disorders. Bifidobacterium adolescentis displays distinct anti-inflammatory effects. However, no report has focused on the anxiolytic and antidepressant effects of B. adol...

journal_title：Frontiers in behavioral neuroscience

authors： Guo Y,Xie JP,Deng K,Li X,Yuan Y,Xuan Q,Xie J,He XM,Wang Q,Li JJ,Luo HR

更新日期：2019-06-18 00:00:00

abstract：:Testosterone reduces anxiety-like behaviors in rodents and increases exploration of anxiogenic parts of the environment. Effects of testosterone on innate defensive behaviors remain understudied. Here, we demonstrate that exogenous testosterone reduces aversion to cat odor in male mice. This is reflected as increased ...

journal_title：Frontiers in behavioral neuroscience

authors： Tong WH,Abdulai-Saiku S,Vyas A

更新日期：2019-02-26 00:00:00

abstract：BACKGROUND:Previous studies investigated neural substrates of emotional face processing in adolescents and its comparison with adults. As emotional faces elicit more of emotional expression recognition rather than direct emotional responding, it remains undetermined how adolescents are different from adults in brain su...

journal_title：Frontiers in behavioral neuroscience

authors： Yuan J,Ju E,Meng X,Chen X,Zhu S,Yang J,Li H

更新日期：2015-04-28 00:00:00

abstract：:The synthetic estrogen 17α-ethinylestradiol (EE2) is an endocrine disrupting compound of concern due to its persistence and widespread presence in the aquatic environment. Effects of developmental exposure to low concentrations of EE2 in fish on reproduction and behavior not only persisted to adulthood, but have also ...

journal_title：Frontiers in behavioral neuroscience

authors： Porseryd T,Volkova K,Reyhanian Caspillo N,Källman T,Dinnetz P,Porsh Hällström I

更新日期：2017-04-20 00:00:00

abstract：:Environmental enrichment (EE) is an experimental setting broadly used for investigating the effects of complex social, cognitive, and sensorimotor stimulations on brain structure and function. Recent studies point out that parental EE experience, even occurring in the pre-reproductive phase, affects neural development...

journal_title：Frontiers in behavioral neuroscience

authors： Cutuli D,Berretta E,Pasqualini G,De Bartolo P,Caporali P,Laricchiuta D,Sampedro-Piquero P,Gelfo F,Pesoli M,Foti F,Begega A,Petrosini L

更新日期：2017-05-09 00:00:00

abstract：:Parkinsonian patients experience not only the physical discomfort of motor disorders but also the considerable psychological distress caused by cognitive deficits and behavioral disorders. These two factors can result in a disruption of social relationships during the symptomatic and even the presymptomatic motor stat...

journal_title：Frontiers in behavioral neuroscience

authors： Durand E,Petit O,Tremblay L,Zimmer C,Sgambato-Faure V,Chassain C,Laurent M,Pereira B,Silberberg C,Durif F

更新日期：2015-02-26 00:00:00

abstract：:During active tactile exploration with their whiskers (vibrissae), rodents can rapidly orient to an object even though there are very few proprioceptors in the whisker muscles. Thus a long-standing question in the study of the vibrissal system is how the rat can localize an object in head-centered coordinates without ...

journal_title：Frontiers in behavioral neuroscience

authors： Yang AE,Hartmann MJ

更新日期：2016-07-19 00:00:00

abstract：:Major advances in the past decade have led a better understanding of the pathophysiology of narcolepsy with cataplexy (NC) caused by the early loss of hypothalamic hypocretin neurons. Although a role for hypocretin in the regulation of sleep/wakefulness state is widely recognized, other functions, not necessarily rela...

journal_title：Frontiers in behavioral neuroscience

authors： Bayard S,Dauvilliers YA

更新日期：2013-05-23 00:00:00

abstract：:Darwin (1872) postulated that emotional expressions contain universals that are retained across species. We recently showed that human rating responses were strongly affected by a listener's familiarity with vocalization types, whereas evidence for universal cross-taxa emotion recognition was limited. To disentangle t...

journal_title：Frontiers in behavioral neuroscience

authors： Scheumann M,Hasting AS,Zimmermann E,Kotz SA

更新日期：2017-10-24 00:00:00

abstract：:Although previous studies have suggested that depression may be associated with inhibition of evoked pain but facilitation of spontaneous pain, the mechanisms underlying these relationships are unclear. The present study investigated whether the difference between evoked and spontaneous pain on sensory (descending inh...

journal_title：Frontiers in behavioral neuroscience

authors： Wang N,Li SG,Lin XX,Su YL,Qi WJ,Wang JY,Luo F

更新日期：2016-09-28 00:00:00

abstract：:Previous research has shown that exposure to violent video games increases aggression, whereas exposure to prosocial video games can reduce aggressive behavior. However, little is known about the neural correlates of these behavioral effects. This work is the first to investigate the electrophysiological features of t...

journal_title：Frontiers in behavioral neuroscience

authors： Liu Y,Teng Z,Lan H,Zhang X,Yao D

更新日期：2015-07-24 00:00:00

abstract：:The ability to accurately integrate or bind stimuli from more than one sensory modality is highly dependent on the features of the stimuli, such as their intensity and relative timing. Previous studies have demonstrated that the ability to perceptually bind stimuli is impaired in various clinical conditions such as au...

journal_title：Frontiers in behavioral neuroscience

authors： Schormans AL,Allman BL

更新日期：2018-10-31 00:00:00

abstract：:This study investigated the effects of early institutional care on memory and executive functioning. Subjects were participants in the Bucharest Early Intervention Project (BEIP) and included institutionalized children, children with a history of institutionalization who were assigned to a foster care intervention, an...

journal_title：Frontiers in behavioral neuroscience

authors： Bos KJ,Fox N,Zeanah CH,Nelson Iii CA

更新日期：2009-09-01 00:00:00