Pupil Dynamics Reflect Behavioral Choice and Learning in a Go/NoGo Tactile Decision-Making Task in Mice.

abstract：:Parkinson's disease is a neurodegenerative disorder characterized by motor and non-motor disturbances. Various pathogenic pathways drive disease progression including oxidative stress, mitochondrial dysfunction, α-synuclein aggregation and impairment of protein degradation systems. Dysfunction of the ubiquitin-proteas...

journal_title：Frontiers in behavioral neuroscience

authors： Bentea E,Van der Perren A,Van Liefferinge J,El Arfani A,Albertini G,Demuyser T,Merckx E,Michotte Y,Smolders I,Baekelandt V,Massie A

更新日期：2015-03-31 00:00:00

abstract：:This study analyzed ethanol intake in male and female Wistar rats exposed to maternal separation (MS) during infancy (postnatal days 1-21, PD1-21) and environmental enrichment (EE) during adolescence (PD 21-42). Previous work revealed that MS enhances ethanol consumption during adulthood. It is still unknown if a simi...

journal_title：Frontiers in behavioral neuroscience

authors： Berardo LR,Fabio MC,Pautassi RM

更新日期：2016-10-13 00:00:00

abstract：:Trauma- and stress-related disorders are among the most common types of mental illness affecting the U.S. population. For many of these disorders, there is a striking sex difference in lifetime prevalence; for instance, women are twice as likely as men to be affected by posttraumatic stress disorder (PTSD). Gonadal st...

journal_title：Frontiers in behavioral neuroscience

authors： Nagaya N,Acca GM,Maren S

更新日期：2015-08-04 00:00:00

abstract：:According to recent WHO reports, alcohol remains the number one substance used and abused by adolescents, despite public health efforts to curb its use. Adolescence is a critical period of biological maturation where brain development, particularly the mesocorticolimbic dopamine system, undergoes substantial remodelin...

journal_title：Frontiers in behavioral neuroscience

authors： Kruse LC,Schindler AG,Williams RG,Weber SJ,Clark JJ

更新日期：2017-07-25 00:00:00

abstract：:The role of Y chromosome in sex determination and male fertility is well established. It is also known that infertile men are prone to psychological disturbances. Earlier studies in the laboratory identified genes expressed in testes that are putatively regulated by Y chromosome in man and mouse. With the availability...

journal_title：Frontiers in behavioral neuroscience

authors： Dey SK,Kamle A,Dereddi RR,Thomas SM,Thummala SR,Kumar A,Chakravarty S,Jesudasan RA

更新日期：2018-09-21 00:00:00

abstract：:Selective serotonin reuptake inhibitors (SSRIs) are used extensively in the treatment of depression and anxiety disorders. The therapeutic benefits of SSRIs typically require several weeks of continuous treatment. Intriguingly, according to clinical reports, symptoms of anxiety may actually increase during the early s...

journal_title：Frontiers in behavioral neuroscience

authors： Ravinder S,Pillai AG,Chattarji S

更新日期：2011-12-28 00:00:00

abstract：:Beneficial molecular and neuroplastic changes have been demonstrated in response to environmental enrichment (EE) in laboratory animals across the lifespan. Here, we investigated whether these effects extend to C-type Natriuretic Peptide (CNP), a widely expressed neuropeptide with putative involvement in neuroprotecti...

journal_title：Frontiers in behavioral neuroscience

authors： Rapley SA,Prickett TCR,Dalrymple-Alford JC,Espiner EA

更新日期：2018-07-19 00:00:00

abstract：:Social cognition and social behaviors are complex phenomena that involve numerous brain areas and underlying neurobiological mechanisms. Embryonic alcohol exposure may lead to the development of Fetal Alcohol Spectrum Disorder (FASD), a disorder that manifests with varying symptoms including abnormal social behavior a...

journal_title：Frontiers in behavioral neuroscience

authors： Facciol A,Gerlai R

更新日期：2020-09-25 00:00:00

abstract：:Extensive evidence indicates that glucocorticoid hormones act in a variety of brain regions to enhance the consolidation of memory of emotionally motivated training experiences. We previously reported that corticosterone, the major glucocorticoid in the rat, administered into the dorsal striatum immediately after inhi...

journal_title：Frontiers in behavioral neuroscience

authors： Sánchez-Resendis O,Medina AC,Serafín N,Prado-Alcalá RA,Roozendaal B,Quirarte GL

更新日期：2012-06-22 00:00:00

abstract：:The underlying mechanisms of paternal responses to infant signals are poorly understood. Vasopressin has previously been proposed to affect these responses. Using a double-blind, placebo-controlled, within-subject design (N = 25 expectant fathers), we examined the effect of vasopressin administration on the use of exc...

journal_title：Frontiers in behavioral neuroscience

authors： Alyousefi-van Dijk K,van 't Veer AE,Meijer WM,Lotz AM,Rijlaarsdam J,Witteman J,Bakermans-Kranenburg MJ

更新日期：2019-05-21 00:00:00

abstract：:Objective: This study utilized different theoretical perspectives to better understand motor performance. We refered to concepts of achievement motive-goal incongruence and assessed cortical correlates of self-control. We assumed that more self-control is required when people act in conformance with an incongruent goa...

journal_title：Frontiers in behavioral neuroscience

authors： Schüler J,Hofstetter J,Wolff W

更新日期：2019-10-04 00:00:00

abstract：:Anatomical investigations have revealed connections between the intralaminar thalamic nuclei and areas such as the superior colliculus (SC) that receive short latency input from visual and auditory primary sensory areas. The intralaminar nuclei in turn project to the major input nucleus of the basal ganglia, the stria...

journal_title：Frontiers in behavioral neuroscience

authors： Fisher SD,Reynolds JN

更新日期：2014-04-02 00:00:00

abstract：:Several lines of evidence suggest the involvement of prefrontal cortex in time interval estimation. The underlying neural processes are poorly understood, however, in part because of the paucity of physiological studies. The goal of this study was to establish an interval timing task for physiological recordings in ra...

journal_title：Frontiers in behavioral neuroscience

authors： Kim J,Jung AH,Byun J,Jo S,Jung MW

更新日期：2009-11-03 00:00:00

abstract：:This study investigated the effects of early institutional care on memory and executive functioning. Subjects were participants in the Bucharest Early Intervention Project (BEIP) and included institutionalized children, children with a history of institutionalization who were assigned to a foster care intervention, an...

journal_title：Frontiers in behavioral neuroscience

authors： Bos KJ,Fox N,Zeanah CH,Nelson Iii CA

更新日期：2009-09-01 00:00:00

abstract：:Identifying the biological substrates of complex neurobehavioral traits such as alcohol dependency pose a tremendous challenge given the diverse model systems and phenotypic assessments used. To address this problem we have developed a platform for integrated analysis of high-throughput or genome-wide functional genom...

journal_title：Frontiers in behavioral neuroscience

authors： Bubier JA,Wilcox TD,Jay JJ,Langston MA,Baker EJ,Chesler EJ

更新日期：2016-01-21 00:00:00

abstract：:An imbalance in the neural motivational system may underlie Social Anxiety Disorder (SAD). This study examines social reward and punishment anticipation in SAD, predicting a valence-specific effect: increased striatal activity for punishment avoidance compared to obtaining a reward. Individuals with SAD (n = 20) and a...

journal_title：Frontiers in behavioral neuroscience

authors： Cremers HR,Veer IM,Spinhoven P,Rombouts SA,Roelofs K

更新日期：2015-01-05 00:00:00

abstract：:Work and study increasingly rely on the use of technologies requiring individuals to switch attention rapidly between emails, texts and tasks. This has led to healthy people having problems of attention and concentration and difficulties getting into the "flow," which impedes goal attainment and task completion. Possi...

journal_title：Frontiers in behavioral neuroscience

authors： Savulich G,Thorp E,Piercy T,Peterson KA,Pickard JD,Sahakian BJ

更新日期：2019-01-21 00:00:00

abstract：:A developing literature explores the use of neurofeedback in the treatment of a range of clinical conditions, particularly ADHD and epilepsy, whilst neurofeedback also provides an experimental tool for studying the functional significance of endogenous brain activity. A critical component of any neurofeedback method i...

journal_title：Frontiers in behavioral neuroscience

authors： White DJ,Congedo M,Ciorciari J

更新日期：2014-10-22 00:00:00

abstract：:Molecular processes in GABAergic local circuit neurons critically contribute to information processing in the hippocampus and to stress-induced activation of the amygdala. In the current study, we determined expression changes in GABA-related factors induced in subregions of the dorsal hippocampus as well as in the BL...

journal_title：Frontiers in behavioral neuroscience

authors： Hadad-Ophir O,Albrecht A,Stork O,Richter-Levin G

更新日期：2014-01-21 00:00:00

abstract：:Visual attention is an important condition for consumer decision-making. However, not much is known on individuals' determinants of this visual attention. Using eye tracking, this study investigated how psychological values (i.e., materialism) modulate visual attention to specific sources of information (i.e., product...

journal_title：Frontiers in behavioral neuroscience

authors： Audrin C,Brosch T,Sander D,Chanal J

更新日期：2018-08-24 00:00:00

abstract：:"Social facilitation" refers to the enhancement or impairment of performance engendered by the mere presence of others. It has been demonstrated for a diversity of behaviors. This study assessed whether it also concerns attention and eye movements and if yes, which decision-making mechanisms it affects. Human voluntee...

journal_title：Frontiers in behavioral neuroscience

authors： Tricoche L,Ferrand-Verdejo J,Pélisson D,Meunier M

更新日期：2020-01-08 00:00:00

abstract：:Emotional events gain special priority in how they are remembered, with emotionally arousing events typically recalled more vividly and with greater confidence than non-emotional events. In dementia, memory and emotion processing are affected to varying degrees, however, whether emotional enhancement of memory for com...

journal_title：Frontiers in behavioral neuroscience

authors： Kumfor F,Irish M,Hodges JR,Piguet O

更新日期：2014-06-24 00:00:00

abstract：:Neuroplasticity accounts for the ability of the brain to change in both structure and function in consequence of life experiences. An enhanced stimulation provided by the environment is able to create a form of brain, neural, and cognitive reserve, which allows an individual to cope better with the environmental deman...

journal_title：Frontiers in behavioral neuroscience

authors： Gelfo F

更新日期：2019-07-09 00:00:00

abstract：:Epilepsy is a chronic neurological disease which is usually associated with psychiatric comorbidities. Depsression and cognition impairment are considered to be the most common psychiatric comorbidities in epilepsy patients. However, the specific contribution of epilepsy made to these psychiatric comorbidities remains...

journal_title：Frontiers in behavioral neuroscience

authors： Zhu X,Dong J,Han B,Huang R,Zhang A,Xia Z,Chang H,Chao J,Yao H

更新日期：2017-10-18 00:00:00

abstract：:Disgust is a natural defensive emotion that has evolved to protect against potential sources of contamination and has been recently linked to moral judgements in many studies. However, that people often report feelings of disgust when thinking about feces or moral transgressions alike does not necessarily mean that th...

journal_title：Frontiers in behavioral neuroscience

authors： Oaten M,Stevenson RJ,Williams MA,Rich AN,Butko M,Case TI

更新日期：2018-08-22 00:00:00

abstract：:Dysregulation of the hypothalamic-pituitary-adrenal (HPA) stress response has been suggested to play a role in vulnerability to stress-related disorders, such as depression. Prenatal alcohol exposure (PAE) may result in HPA dysregulation, which in turn may predispose individuals to the effects of stress exposure throu...

journal_title：Frontiers in behavioral neuroscience

authors： Lam VYY,Raineki C,Takeuchi LE,Ellis L,Woodward TS,Weinberg J

更新日期：2018-03-09 00:00:00

abstract：:First-line treatment of major depression includes administration of a selective serotonin reuptake inhibitor (SSRI), yet studies suggest that remission rates following two trials of an SSRI are <50%. The authors examine the putative biological substrates underlying "treatment resistant depression (TRD)" with the goal ...

journal_title：Frontiers in behavioral neuroscience

authors： Coplan JD,Gopinath S,Abdallah CG,Berry BR

更新日期：2014-05-20 00:00:00

abstract：:Early life events have a crucial role in programming the individual phenotype and exposure to traumatic experiences during infancy can increase later risk for a variety of neuropsychiatric conditions, including mood and anxiety disorders. Animal models of postnatal stress have been developed in rodents to explore mole...

journal_title：Frontiers in behavioral neuroscience

authors： Luchetti A,Oddi D,Lampis V,Centofante E,Felsani A,Battaglia M,D'Amato FR

更新日期：2015-04-21 00:00:00

abstract：:The dopaminergic system is known to be involved in working memory processed by several brain regions like prefrontal cortex (PFC), hippocampus, striatum. In an earlier study we could show that Levodopa but not Modafinil enhanced working memory in a T-maze only during the early phase of training (day 3), whereas the la...

journal_title：Frontiers in behavioral neuroscience

authors： Bezu M,Maliković J,Kristofova M,Engidawork E,Höger H,Lubec G,Korz V

更新日期：2017-10-13 00:00:00

abstract：:We investigated whether the differences in perceptual awareness for stimuli at the threshold of awareness can arise from different global brain states before stimulus onset indexed by the EEG microstate. We used a metacontrast backward masking paradigm in which subjects had to discriminate between two weak stimuli and...

journal_title：Frontiers in behavioral neuroscience

authors： Britz J,Díaz Hernàndez L,Ro T,Michel CM

更新日期：2014-05-14 00:00:00