Testosterone Reduces Fear and Causes Drastic Hypomethylation of Arginine Vasopressin Promoter in Medial Extended Amygdala of Male Mice.

abstract：:PAOPA, a potent analog of prolyl-leucyl-glycinamide, has shown therapeutic potential at the preclinical stage for dopaminergic related illnesses, including animal models of schizophrenia, Parkinson's disease and haloperidol-induced extrapyramidal movement disorders. PAOPA's unique allosteric mechanism and dopamine D2 ...

journal_title：Frontiers in behavioral neuroscience

authors： Daya RP,Bhandari J,Kooner SK,Ho J,Rowley CD,Bock NA,Farncombe T,Mishra RK

更新日期：2018-12-12 00:00:00

abstract：:Numerous studies show that sleep deprivation (SD) impacts negatively on cognitive processes, including learning and memory. Memory formation encompasses distinct phases of which acquisition, consolidation and retrieval are better known. Previous studies with pre-training SD induced by the platform method have shown im...

journal_title：Frontiers in behavioral neuroscience

authors： Rossi VC,Tiba PA,Moreira KD,Ferreira TL,Oliveira MG,Suchecki D

更新日期：2014-11-07 00:00:00

abstract：:Dysregulations in the brain serotonergic system and exposure to environmental stressors have been implicated in the development of major depressive disorder. Here, we investigate the interactions between the stress and serotonergic systems by characterizing the behavioral and biochemical effects of chronic stress appl...

journal_title：Frontiers in behavioral neuroscience

authors： Wong P,Sze Y,Gray LJ,Chang CC,Cai S,Zhang X

更新日期：2015-04-27 00:00:00

abstract：:Methamphetamine (METH) is a psychomotor stimulant that is reported to enhance sexual desire and behavior in both men and women, leading to increases in unplanned pregnancies, sexually-transmitted infections, and even comorbid psychiatric conditions. Here, we discuss our rodent model of increased sexually-motivated beh...

journal_title：Frontiers in behavioral neuroscience

authors： Rudzinskas SA,Williams KM,Mong JA,Holder MK

更新日期：2019-09-10 00:00:00

abstract：:Inflammatory bowel disease is associated with an increased risk of mental disorders and can be exacerbated by stress. In this study which was performed with male 10-week old C57Bl/6N mice, we used dextran sulfate sodium (DSS)-induced colitis to evaluate behavioral changes caused by intestinal inflammation, to assess t...

journal_title：Frontiers in behavioral neuroscience

authors： Hassan AM,Jain P,Reichmann F,Mayerhofer R,Farzi A,Schuligoi R,Holzer P

更新日期：2014-11-06 00:00:00

abstract：:Discrete populations of brain cells signal differing types of spatial information. These "spatial cells" are largely confined to a closely-connected network of sites. We describe here, for the first time, cells in the anterior claustrum of the freely-moving rat encoding place, boundary and object information. This nov...

journal_title：Frontiers in behavioral neuroscience

authors： Jankowski MM,O'Mara SM

更新日期：2015-10-14 00:00:00

abstract：:The relationship between stress and drug use is well demonstrated. Stress-induced by repeated social defeat (RSD) enhances the conditioned place preference (CPP) induced by cocaine in mice. The phenomenon of resilience understood as the ability of subjects to overcome the negative effects of stress is the focus of inc...

journal_title：Frontiers in behavioral neuroscience

authors： Calpe-López C,García-Pardo MP,Martínez-Caballero MA,Santos-Ortíz A,Aguilar MA

更新日期：2020-01-09 00:00:00

abstract：:Down syndrome (DS) individuals present increased risk for Alzheimer's disease (AD) neuropathology and AD-type dementia. Here, we investigated the use of green tea extracts containing (-)-epigallocatechin-3-gallate (EGCG), as co-adjuvant to enhance the effects of environmental enrichment (EE) in Ts65Dn mice, a segmenta...

journal_title：Frontiers in behavioral neuroscience

authors： Catuara-Solarz S,Espinosa-Carrasco J,Erb I,Langohr K,Notredame C,Gonzalez JR,Dierssen M

更新日期：2015-12-11 00:00:00

abstract：:The tendency to make unhealthy choices is hypothesized to be related to an individual's temporal discount rate, the theoretical rate at which they devalue delayed rewards. Furthermore, a particular form of temporal discounting, hyperbolic discounting, has been proposed to explain why unhealthy behavior can occur despi...

journal_title：Frontiers in behavioral neuroscience

authors： Story GW,Vlaev I,Seymour B,Darzi A,Dolan RJ

更新日期：2014-03-12 00:00:00

abstract：:Emotional events gain special priority in how they are remembered, with emotionally arousing events typically recalled more vividly and with greater confidence than non-emotional events. In dementia, memory and emotion processing are affected to varying degrees, however, whether emotional enhancement of memory for com...

journal_title：Frontiers in behavioral neuroscience

authors： Kumfor F,Irish M,Hodges JR,Piguet O

更新日期：2014-06-24 00:00:00

abstract：:When stepping onto a stopped escalator, we often perceive an "odd sensation" that is never felt when stepping onto stairs. The sight of an escalator provides a strong contextual cue that, in expectation of the backward acceleration when stepping on, triggers an anticipatory forward postural adjustment driven by a habi...

journal_title：Frontiers in behavioral neuroscience

authors： Gomi H,Sakurada T,Fukui T

更新日期：2014-03-20 00:00:00

abstract：:The eye's pupil undergoes dynamic changes in diameter associated with cognitive effort, motor activity and emotional state, and can be used to index brain state across mammalian species. Recent studies in head-fixed mice have linked arousal-related pupil dynamics with global neural activity as well as the activity of ...

journal_title：Frontiers in behavioral neuroscience

authors： Lee CR,Margolis DJ

更新日期：2016-11-01 00:00:00

abstract：:The ventral subiculum of the hippocampus projects both to the basolateral amygdala (BLA), which is typically, associated with a response to aversive stimuli, as well as to the nucleus accumbens (NAcc), which is typically associated with a response to appetitive stimuli. Traditionally, studies of the responses to emoti...

journal_title：Frontiers in behavioral neuroscience

authors： Horovitz O,Richter-Levin G

更新日期：2015-03-04 00:00:00

abstract：:Somatostatin (SOM) and somatostatin receptors (SSTR1-4) are present in all olfactory structures, including the olfactory bulb (OB), where SOM modulates physiological gamma rhythms and olfactory discrimination responses. In this work, histological, viral tracing and transgenic approaches were used to characterize SOM c...

journal_title：Frontiers in behavioral neuroscience

authors： Nocera S,Simon A,Fiquet O,Chen Y,Gascuel J,Datiche F,Schneider N,Epelbaum J,Viollet C

更新日期：2019-04-09 00:00:00

abstract：:Molecular processes in GABAergic local circuit neurons critically contribute to information processing in the hippocampus and to stress-induced activation of the amygdala. In the current study, we determined expression changes in GABA-related factors induced in subregions of the dorsal hippocampus as well as in the BL...

journal_title：Frontiers in behavioral neuroscience

authors： Hadad-Ophir O,Albrecht A,Stork O,Richter-Levin G

更新日期：2014-01-21 00:00:00

abstract：:Negative social experiences during adolescence increase the risk of psychiatric disorders in adulthood. Using "resident-intruder" stress, the present study aimed to investigate the effects of adolescent social defeat on emotional and cognitive symptoms associated with psychiatric disorders during adulthood and the eff...

journal_title：Frontiers in behavioral neuroscience

authors： Zhang F,Yuan S,Shao F,Wang W

更新日期：2016-07-20 00:00:00

abstract：:Anesthetics are often used to characterize the activity of single neurons in vivo for their advantages such as reduction of noise level and convenience in noxious stimulations. Urethane has been a widely used anesthetic in thalamic studies under the assumption that sensory signals are still relayed to the thalamus und...

journal_title：Frontiers in behavioral neuroscience

authors： Huh Y,Cho J

更新日期：2013-10-10 00:00:00

abstract：:Although an effective treatment for pediatric brain tumors, cranial radiation therapy (CRT) damages surrounding healthy tissue, thereby disrupting brain development. Animal models of pediatric CRT have primarily relied on visual tasks to assess cognitive impairment. Moreover, there has been a lack of sex comparisons a...

journal_title：Frontiers in behavioral neuroscience

authors： Perez EC,Rodgers SP,Inoue T,Pedersen SE,Leasure JL,Gaber MW

更新日期：2018-08-02 00:00:00

abstract：:Cognitive rehabilitation in multiple sclerosis (MS) has been reported to induce neuropsychological improvements, but the persistence of these effects has been scarcely investigated over long follow ups. Here, the results of a multicenter randomized clinical trial are reported, in which the efficacy of 15 week domain s...

journal_title：Frontiers in behavioral neuroscience

authors： Mattioli F,Bellomi F,Stampatori C,Provinciali L,Compagnucci L,Uccelli A,Pardini M,Santuccio G,Fregonese G,Pattini M,Allegri B,Clerici R,Lattuada A,Montomoli C,Corso B,Gallo P,Riccardi A,Ghezzi A,Roscio M,Tola MR,C

更新日期：2016-02-23 00:00:00

abstract：:Many epidemiological studies have described an adolescent-related psychiatric illness and sensorimotor deficits after Glyphosate based herbicide (GBH) exposure. GBH exposure in animal models of various ages suggests that it may be neurotoxic and could impact brain development and subsequently, behavior in adulthood. H...

journal_title：Frontiers in behavioral neuroscience

authors： Ait Bali Y,Ba-Mhamed S,Bennis M

更新日期：2017-08-08 00:00:00

abstract：:Parkinson's disease is a neurodegenerative disorder characterized by motor and non-motor disturbances. Various pathogenic pathways drive disease progression including oxidative stress, mitochondrial dysfunction, α-synuclein aggregation and impairment of protein degradation systems. Dysfunction of the ubiquitin-proteas...

journal_title：Frontiers in behavioral neuroscience

authors： Bentea E,Van der Perren A,Van Liefferinge J,El Arfani A,Albertini G,Demuyser T,Merckx E,Michotte Y,Smolders I,Baekelandt V,Massie A

更新日期：2015-03-31 00:00:00

abstract：:Olfactory processing in behaving animals, even at early stages, is inextricable from top down influences associated with odor perception. The anatomy of the olfactory network (olfactory bulb, piriform, and entorhinal cortices) and its unique direct access to the limbic system makes it particularly attractive to study ...

journal_title：Frontiers in behavioral neuroscience

authors： Martin C,Ravel N

更新日期：2014-06-23 00:00:00

abstract：:Pyriproxyfen is one of the most used larvicides and insecticides; it acts as an analog of juvenile insect hormone (a growth regulator). It is highly toxic during all stages of mosquito development, suppresses metamorphosis, and interferes in insect reproduction and proliferation. Pyriproxyfen and its main metabolite h...

journal_title：Frontiers in behavioral neuroscience

authors： Gusso D,Reolon GK,Gonzalez JB,Altenhofen S,Kist LW,Bogo MR,Bonan CD

更新日期：2020-06-17 00:00:00

abstract：:The honeybee has been established as an important model organism in studies on visual learning. So far the emphasis has been on appetitive conditioning, simulating floral discrimination, and homing behavior, where bees perform exceptionally well in visual discrimination tasks. However, bees in the wild also face dange...

journal_title：Frontiers in behavioral neuroscience

authors： Kirkerud NH,Schlegel U,Giovanni Galizia C

更新日期：2017-05-22 00:00:00

abstract：:The extant literature supports the role of stress in enhancing the susceptibility of drug abuse progressing to a substance use disorder diagnosis. However, the molecular mediators by which stress enhances the progression from cocaine abuse to cocaine use disorder via the mesolimbic pathway remain elusive. In this mini...

journal_title：Frontiers in behavioral neuroscience

authors： Mukhara D,Banks ML,Neigh GN

更新日期：2018-12-21 00:00:00

abstract：:Adolescence is a time of unique sensitivity to socially salient stimuli such as social rewards. This period overlaps with the onset of psychopathology such as internalizing and externalizing symptoms. In the current studies, we examined behavioral and neural patterns of dysregulation to social rewards and threats, and...

journal_title：Frontiers in behavioral neuroscience

authors： Kwon SJ,Ivory SL,McCormick EM,Telzer EH

更新日期：2019-07-23 00:00:00

abstract：BACKGROUND:Previous studies investigated neural substrates of emotional face processing in adolescents and its comparison with adults. As emotional faces elicit more of emotional expression recognition rather than direct emotional responding, it remains undetermined how adolescents are different from adults in brain su...

journal_title：Frontiers in behavioral neuroscience

authors： Yuan J,Ju E,Meng X,Chen X,Zhu S,Yang J,Li H

更新日期：2015-04-28 00:00:00

abstract：:Associative learning can be observed from the neonatal period onward, providing opportunities to examine changes in basic learning and memory abilities. One method that is suitable to study associative learning is classical eyeblink conditioning (EBC) which is dependent on the cerebellum. Extinction learning can be sy...

journal_title：Frontiers in behavioral neuroscience

authors： Konrad C,Adolph D,Herbert JS,Neuhoff L,Mohr C,Jagusch-Poirier J,Seehagen S,Weigelt S,Schneider S

更新日期：2020-08-14 00:00:00

abstract：:This study analyzed ethanol intake in male and female Wistar rats exposed to maternal separation (MS) during infancy (postnatal days 1-21, PD1-21) and environmental enrichment (EE) during adolescence (PD 21-42). Previous work revealed that MS enhances ethanol consumption during adulthood. It is still unknown if a simi...

journal_title：Frontiers in behavioral neuroscience

authors： Berardo LR,Fabio MC,Pautassi RM

更新日期：2016-10-13 00:00:00

abstract：:Impaired sensorimotor gating occurs in neuropsychiatric disorders such as schizophrenia and can be measured using the prepulse inhibition (PPI) paradigm of the acoustic startle response. This assay is frequently used to validate animal models of neuropsychiatric disorders and to explore the therapeutic potential of ne...

journal_title：Frontiers in behavioral neuroscience

authors： Rohleder C,Jung F,Mertgens H,Wiedermann D,Sué M,Neumaier B,Graf R,Leweke FM,Endepols H

更新日期：2014-05-22 00:00:00