Correction: The spectrum of neurological disease associated with Zika and chikungunya viruses in adults in Rio de Janeiro, Brazil: A case series.


:[This corrects the article DOI: 10.1371/journal.pntd.0006212.].


PLoS Negl Trop Dis


PLOS Neglected Tropical Diseases Staff.




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2019-01-31 00:00:00














  • Antibodies against immature virions are not a discriminating factor for dengue disease severity.

    abstract::Humoral immunity plays an important role in controlling dengue virus (DENV) infection. Antibodies (Abs) developed during primary infection protect against subsequent infection with the same dengue serotype, but can enhance disease following secondary infection with a heterologous serotype. A DENV virion has two surfac...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Rodenhuis-Zybert IA,da Silva Voorham JM,Torres S,van de Pol D,Smit JM

    更新日期:2015-03-11 00:00:00

  • Using detergent-enhanced LAMP for African trypanosome detection in human cerebrospinal fluid and implications for disease staging.

    abstract:OBJECTIVE:Where human African trypanosomiasis (HAT) patients are seen, failure to microscopically diagnose infections by Trypanosoma brucei gambiense in blood smears and/or cerebrospinal fluid (CSF) in the critical early stages of the disease is the single most important factor in treatment failure, a result of delayed...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Grab DJ,Nikolskaia OV,Courtioux B,Thekisoe OMM,Magez S,Bogorad M,Dumler JS,Bisser S

    更新日期:2019-08-19 00:00:00

  • Potential for sylvatic and urban Aedes mosquitoes from Senegal to transmit the new emerging dengue serotypes 1, 3 and 4 in West Africa.

    abstract::Dengue fever (DEN) is the most common arboviral disease in the world and dengue virus (DENV) causes 390 million annual infections around the world, of which 240 million are inapparent and 96 million are symptomatic. During the past decade a changing epidemiological pattern has been observed in Africa, with DEN outbrea...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Gaye A,Wang E,Vasilakis N,Guzman H,Diallo D,Talla C,Ba Y,Dia I,Weaver SC,Diallo M

    更新日期:2019-02-13 00:00:00

  • Molecular evidence for a functional ecdysone signaling system in Brugia malayi.

    abstract:BACKGROUND:Filarial nematodes, including Brugia malayi, the causative agent of lymphatic filariasis, undergo molting in both arthropod and mammalian hosts to complete their life cycles. An understanding of how these parasites cross developmental checkpoints may reveal potential targets for intervention. Pharmacological...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Tzertzinis G,Egaña AL,Palli SR,Robinson-Rechavi M,Gissendanner CR,Liu C,Unnasch TR,Maina CV

    更新日期:2010-03-09 00:00:00

  • Meta-transcriptome Profiling of the Human-Leishmania braziliensis Cutaneous Lesion.

    abstract::Host and parasite gene expression in skin biopsies from Leishmania braziliensis-infected patients were simultaneously analyzed using high throughput RNA-sequencing. Biopsies were taken from 8 patients with early cutaneous leishmaniasis and 17 patients with late cutaneous leishmaniasis. Although parasite DNA was found ...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Christensen SM,Dillon LA,Carvalho LP,Passos S,Novais FO,Hughitt VK,Beiting DP,Carvalho EM,Scott P,El-Sayed NM,Mosser DM

    更新日期:2016-09-15 00:00:00

  • Rabies Risk: Difficulties Encountered during Management of Grouped Cases of Bat Bites in 2 Isolated Villages in French Guiana.

    abstract::In French Guiana, from 1984 to 2011, 14 animal rabies cases and 1 human rabies case (2008) were diagnosed. In January 2011, vampire-bat attacks occurred in 2 isolated villages. In mid-January, a medical team from the Cayenne Centre for Anti-Rabies Treatment visited the sites to manage individuals potentially exposed t...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Berger F,Desplanches N,Baillargeaux S,Joubert M,Miller M,Ribadeau-Dumas F,Spiegel A,Bourhy H

    更新日期:2013-06-27 00:00:00

  • Ultrasound-guided minimally invasive autopsy as a tool for rapid post-mortem diagnosis in the 2018 Sao Paulo yellow fever epidemic: Correlation with conventional autopsy.

    abstract:BACKGROUND:New strategies for collecting post-mortem tissue are necessary, particularly in areas with emerging infections. Minimally invasive autopsy (MIA) has been proposed as an alternative to conventional autopsy (CA), with promising results. Previous studies using MIA addressed the cause of death in adults and chil...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Duarte-Neto AN,Monteiro RAA,Johnsson J,Cunha MDP,Pour SZ,Saraiva AC,Ho YL,da Silva LFF,Mauad T,Zanotto PMA,Saldiva PHN,de Oliveira IRS,Dolhnikoff M

    更新日期:2019-07-22 00:00:00

  • Multi-disease data management system platform for vector-borne diseases.

    abstract:BACKGROUND:Emerging information technologies present new opportunities to reduce the burden of malaria, dengue and other infectious diseases. For example, use of a data management system software package can help disease control programs to better manage and analyze their data, and thus enhances their ability to carry ...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Eisen L,Coleman M,Lozano-Fuentes S,McEachen N,Orlans M,Coleman M

    更新日期:2011-03-29 00:00:00

  • Last generation triazoles for imported eumycetoma in eleven consecutive adults.

    abstract:BACKGROUND:Optimal management of eumycetoma, a severely debilitating chronic progressive fungal infection of skin, disseminating to bone and viscera, remains challenging. Especially, optimal antifungal treatment and duration are ill defined. METHODOLOGY/PRINCIPAL FINDINGS:We conducted a monocentric retrospective study...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Crabol Y,Poiree S,Bougnoux ME,Maunoury C,Barete S,Zeller V,Arvieux C,Pineau S,Amazzough K,Lecuit M,Lanternier F,Lortholary O,French Mycosis Study Group.

    更新日期:2014-10-09 00:00:00

  • Plasmodium vivax but Not Plasmodium falciparum Blood-Stage Infection in Humans Is Associated with the Expansion of a CD8+ T Cell Population with Cytotoxic Potential.

    abstract::P. vivax and P. falciparum parasites display different tropism for host cells and induce very different clinical symptoms and pathology, suggesting that the immune responses required for protection may differ between these two species. However, no study has qualitatively compared the immune responses to P. falciparum ...

    journal_title:PLoS neglected tropical diseases

    pub_type: 临床试验,杂志文章


    authors: Burel JG,Apte SH,McCarthy JS,Doolan DL

    更新日期:2016-12-08 00:00:00

  • The feasibility of canine rabies elimination in Africa: dispelling doubts with data.

    abstract:BACKGROUND:Canine rabies causes many thousands of human deaths every year in Africa, and continues to increase throughout much of the continent. METHODOLOGY/PRINCIPAL FINDINGS:This paper identifies four common reasons given for the lack of effective canine rabies control in Africa: (a) a low priority given for disease...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Lembo T,Hampson K,Kaare MT,Ernest E,Knobel D,Kazwala RR,Haydon DT,Cleaveland S

    更新日期:2010-02-23 00:00:00

  • Clinical, etiological and epidemiological investigations of hand, foot and mouth disease in southern Vietnam during 2015 - 2018.

    abstract::Hand, foot and mouth disease (HFMD) continues to challenge Asia with pandemic potential. In Vietnam, there have been two major outbreaks occurring during 2011-2012 (>200,000 hospitalizations and >200 deaths) and more recently in 2018 (>130,000 hospitalizations and 17 deaths). Given the high burden and the complex epid...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Nhan LNT,Khanh TH,Hong NTT,Van HMT,Nhu LNT,Ny NTH,Nguyet LA,Thanh TT,Anh NT,Hang VTT,Qui PT,Viet HL,Tung TH,Ha DQ,Tuan HM,Thwaites G,Chau NVV,Thwaites L,Hung NT,van Doorn HR,Tan LV

    更新日期:2020-08-17 00:00:00

  • Evaluation of Chikungunya diagnostic assays: differences in sensitivity of serology assays in two independent outbreaks.

    abstract:BACKGROUND:The sensitivity and specificity of two in-house MAC-ELISA assays were tested and compared with the performance of commercially-available CTK lateral flow rapid test and EUROIMMUN IFA assays for the detection of anti-Chikungunya virus (CHIKV) IgM. Each MAC-ELISA assay used a whole virus-based antigen derived ...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Yap G,Pok KY,Lai YL,Hapuarachchi HC,Chow A,Leo YS,Tan LK,Ng LC

    更新日期:2010-07-20 00:00:00

  • Copulation Activity, Sperm Production and Conidia Transfer in Aedes aegypti Males Contaminated by Metarhizium anisopliae: A Biological Control Prospect.

    abstract:BACKGROUND:Dengue is the most prevalent arboviral disease transmitted by Aedes aegypti worldwide, whose chemical control is difficult, expensive, and of inconsistent efficacy. Releases of Metarhizium anisopliae--exposed Ae. aegypti males to disseminate conidia among female mosquitoes by mating represents a promising bi...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Garza-Hernández JA,Reyes-Villanueva F,Russell TL,Braks MA,Garcia-Munguia AM,Rodríguez-Pérez MA

    更新日期:2015-10-16 00:00:00

  • Sero-Molecular Epidemiology of Japanese Encephalitis in Zhejiang, an Eastern Province of China.

    abstract:BACKGROUND:Sporadic Japanese encephalitis (JE) cases still have been reported in Zhejiang Province in recent years, and concerns about vaccine cross-protection and population-level immunity have been raised off and on within the public health sphere. Genotype I (GI) has replaced GIII as the dominant genotype in Asian c...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Pan JR,Yan JY,Zhou JY,Tang XW,He HQ,Xie RH,Mao HY,Zhang YJ,Xie SY

    更新日期:2016-08-25 00:00:00

  • Molecular identification and antifungal susceptibility profiles of clinical strains of Fonsecaea spp. isolated from patients with chromoblastomycosis in Rio de Janeiro, Brazil.

    abstract:BACKGROUND:Chromoblastomycosis (CBM) is a difficult-to-treat chronic subcutaneous mycosis. In Brazil, the main agent of this disease is Fonsecaea pedrosoi, which is phenotypically very similar to other Fonsecaea species, differing only genetically. The correct species identification is relevant since different species ...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Coelho RA,Brito-Santos F,Figueiredo-Carvalho MHG,Silva JVDS,Gutierrez-Galhardo MC,do Valle ACF,Zancopé-Oliveira RM,Trilles L,Meyer W,Freitas DFS,Almeida-Paes R

    更新日期:2018-07-26 00:00:00

  • A thrombomodulin mutation that impairs active protein C generation is detrimental in severe pneumonia-derived gram-negative sepsis (melioidosis).

    abstract:BACKGROUND:During severe (pneumo)sepsis inflammatory and coagulation pathways become activated as part of the host immune response. Thrombomodulin (TM) is involved in a range of host defense mechanisms during infection and plays a pivotal role in activation of protein C (PC) into active protein C (APC). APC has both an...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Kager LM,Wiersinga WJ,Roelofs JJ,de Boer OJ,Weiler H,van 't Veer C,van der Poll T

    更新日期:2014-04-24 00:00:00

  • Prevalence of Chagas disease in Latin-American migrants living in Europe: a systematic review and meta-analysis.

    abstract:BACKGROUND:Few studies have assessed the burden of Chagas disease in non-endemic countries and most of them are based on prevalence estimates from Latin American (LA) countries that likely differ from the prevalence in migrants living in Europe. The aim of this study was to systematically review the existing data infor...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章,meta分析,评审


    authors: Requena-Méndez A,Aldasoro E,de Lazzari E,Sicuri E,Brown M,Moore DA,Gascon J,Muñoz J

    更新日期:2015-02-13 00:00:00

  • Zika virus like particles elicit protective antibodies in mice.

    abstract::Mosquito-borne Zika virus (ZIKV) typically causes a mild and self-limiting illness known as Zika fever. Since its recent emergence in 2014 in the American continent, ZIKV infection during pregnancy has been closely associated with a wide range of congenital abnormalities. To date, no vaccines or antivirals are publicl...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Salvo MA,Kingstad-Bakke B,Salas-Quinchucua C,Camacho E,Osorio JE

    更新日期:2018-02-05 00:00:00

  • Estimated incidence and Prevalence of noma in north central Nigeria, 2010-2018: A retrospective study.

    abstract:BACKGROUND:Noma is a spreading and fulminant disease believed to be native to Sub-Saharan Africa over the last decade and associated with low socioeconomic status of citizens of the region. Within this noma belt, most epidemiological reports regarding the disease have emanated from the north western region of Nigeria. ...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Bello SA,Adeoye JA,Oketade I,Akadiri OA

    更新日期:2019-07-22 00:00:00

  • Epidemiology of Infant Dengue Cases Illuminates Serotype-Specificity in the Interaction between Immunity and Disease, and Changes in Transmission Dynamics.

    abstract:BACKGROUND:Infants born to dengue immune mothers acquire maternal antibodies to dengue. These antibodies, though initially protective, decline during the first year of life to levels thought to be disease enhancing, before reaching undetectable levels. Infants have long been studied to understand the interaction betwee...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Clapham H,Cummings DA,Nisalak A,Kalayanarooj S,Thaisomboonsuk B,Klungthong C,Fernandez S,Srikiatkhachorn A,Macareo LR,Lessler J,Reiser J,Yoon IK

    更新日期:2015-12-11 00:00:00

  • Neglected tropical diseases in children: An assessment of gaps in research prioritization.

    abstract:BACKGROUND:Despite the known burden of neglected tropical diseases (NTDs) on child health, there is limited information on current efforts to increase pediatric therapeutic options. Our objective was to quantify and characterize research activity and treatment availability for NTDs in children in order to inform the pr...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Rees CA,Hotez PJ,Monuteaux MC,Niescierenko M,Bourgeois FT

    更新日期:2019-01-29 00:00:00

  • The ectodomains of the lymphocyte scavenger receptors CD5 and CD6 interact with tegumental antigens from Echinococcus granulosus sensu lato and protect mice against secondary cystic echinococcosis.

    abstract:BACKGROUND:Scavenger Receptors (SRs) from the host's innate immune system are known to bind multiple ligands to promote the removal of non-self or altered-self targets. CD5 and CD6 are two highly homologous class I SRs mainly expressed on all T cells and the B1a cell subset, and involved in the fine tuning of activatio...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Mourglia-Ettlin G,Miles S,Velasco-De-Andrés M,Armiger-Borràs N,Cucher M,Dematteis S,Lozano F

    更新日期:2018-11-30 00:00:00

  • The global burden of alveolar echinococcosis.

    abstract:BACKGROUND:Human alveolar echinococcosis (AE) is known to be common in certain rural communities in China whilst it is generally rare and sporadic elsewhere. The objective of this study was to provide a first estimate of the global incidence of this disease by country. The second objective was to estimate the global di...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章,评审


    authors: Torgerson PR,Keller K,Magnotta M,Ragland N

    更新日期:2010-06-22 00:00:00

  • Hospital-based surveillance for viral hemorrhagic fevers and hepatitides in Ghana.

    abstract:BACKGROUND:Viral hemorrhagic fevers (VHF) are acute diseases associated with bleeding, organ failure, and shock. VHF may hardly be distinguished clinically from other diseases in the African hospital, including viral hepatitis. This study was conducted to determine if VHF and viral hepatitis contribute to hospital morb...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Bonney JH,Osei-Kwasi M,Adiku TK,Barnor JS,Amesiya R,Kubio C,Ahadzie L,Olschläger S,Lelke M,Becker-Ziaja B,Pahlmann M,Günther S

    更新日期:2013-09-19 00:00:00

  • Telacebec (Q203)-containing intermittent oral regimens sterilized mice infected with Mycobacterium ulcerans after only 16 doses.

    abstract::Buruli ulcer (BU), caused by Mycobacterium ulcerans, is currently treated with a daily combination of rifampin and either injectable streptomycin or oral clarithromycin. An intermittent oral regimen would facilitate treatment supervision. We first evaluated the bactericidal activity of newer antimicrobials against M. ...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Chauffour A,Robert J,Veziris N,Aubry A,Pethe K,Jarlier V

    更新日期:2020-08-31 00:00:00

  • A non mouse-adapted dengue virus strain as a new model of severe dengue infection in AG129 mice.

    abstract::The spread of dengue (DEN) worldwide combined with an increased severity of the DEN-associated clinical outcomes have made this mosquito-borne virus of great global public health importance. Progress in understanding DEN pathogenesis and in developing effective treatments has been hampered by the lack of a suitable sm...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Tan GK,Ng JK,Trasti SL,Schul W,Yip G,Alonso S

    更新日期:2010-04-27 00:00:00

  • Mechanisms of pyrethroid resistance in the dengue mosquito vector, Aedes aegypti: target site insensitivity, penetration, and metabolism.

    abstract::Aedes aegypti is the major vector of yellow and dengue fevers. After 10 generations of adult selection, an A. aegypti strain (SP) developed 1650-fold resistance to permethrin, which is one of the most widely used pyrethroid insecticides for mosquito control. SP larvae also developed 8790-fold resistance following sele...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Kasai S,Komagata O,Itokawa K,Shono T,Ng LC,Kobayashi M,Tomita T

    更新日期:2014-06-19 00:00:00

  • Estimating the cost of illness and burden of disease associated with the 2014-2015 chikungunya outbreak in the U.S. Virgin Islands.

    abstract::Chikungunya virus (CHIKV), an alphavirus that causes fever and severe polyarthralgia, swept through the Americas in 2014 with almost 2 million suspected or confirmed cases reported by April 2016. In this study, we estimate the direct medical costs, cost of lost wages due to absenteeism, and years lived with disability...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Feldstein LR,Ellis EM,Rowhani-Rahbar A,Hennessey MJ,Staples JE,Halloran ME,Weaver MR

    更新日期:2019-07-19 00:00:00

  • Cholera Transmission in Ouest Department of Haiti: Dynamic Modeling and the Future of the Epidemic.

    abstract::In the current study, a comprehensive, data driven, mathematical model for cholera transmission in Haiti is presented. Along with the inclusion of short cycle human-to-human transmission and long cycle human-to-environment and environment-to-human transmission, this novel dynamic model incorporates both the reported c...

    journal_title:PLoS neglected tropical diseases

    pub_type: 杂志文章


    authors: Kirpich A,Weppelmann TA,Yang Y,Ali A,Morris JG Jr,Longini IM

    更新日期:2015-10-21 00:00:00