Body lice of homeless people reveal the presence of several emerging bacterial pathogens in northern Algeria.

abstract：BACKGROUND:In 2005, there were outbreaks of febrile polyarthritis due to Chikungunya virus (CHIKV) in the Comoros Islands. CHIKV then spread to other islands in the Indian Ocean: La Réunion, Mauritius, Seychelles and Madagascar. These outbreaks revealed the lack of surveillance and preparedness of Madagascar and other ...

journal_title：PLoS neglected tropical diseases

authors： Andriamandimby SF,Heraud JM,Randrianasolo L,Rafisandratantsoa JT,Andriamamonjy S,Richard V

更新日期：2013-07-25 00:00:00

abstract：BACKGROUND:Schistosome cercariae are the human-infectious stage of the Schistosoma parasite. They are shed by snail intermediate hosts living in freshwater, and penetrate the skin of the human host to develop into schistosomes, resulting in schistosomiasis infection. Water treatment (e.g. filtration or chlorination) is...

journal_title：PLoS neglected tropical diseases

authors： Braun L,Hazell L,Webb AJ,Allan F,Emery AM,Templeton MR

更新日期：2020-03-26 00:00:00

abstract：BACKGROUND:Visceral leishmaniasis (VL) in human immunodeficiency virus (HIV) co-infected patients requires special case management. AmBisome monotherapy at 40 mg/kg is recommended by the World Health Organization. The objective of the study was to assess if a combination of a lower dose of AmBisome with miltefosine wou...

journal_title：PLoS neglected tropical diseases

authors： Diro E,Blesson S,Edwards T,Ritmeijer K,Fikre H,Admassu H,Kibret A,Ellis SJ,Bardonneau C,Zijlstra EE,Soipei P,Mutinda B,Omollo R,Kimutai R,Omwalo G,Wasunna M,Tadesse F,Alves F,Strub-Wourgaft N,Hailu A,Alexander N,

更新日期：2019-01-17 00:00:00

abstract：BACKGROUND:Noma is a gangrenous disease that leads to severe disfigurement of the face with high morbidity and mortality, but its etiology remains unknown. Young children in developing countries are almost exclusively affected. The purpose of the study was to record and compare bacterial diversity in oral samples from ...

journal_title：PLoS neglected tropical diseases

authors： Bolivar I,Whiteson K,Stadelmann B,Baratti-Mayer D,Gizard Y,Mombelli A,Pittet D,Schrenzel J,Geneva Study Group on Noma (GESNOMA).

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Melioidosis, a fatal infectious disease caused by Burkholderia pseudomallei, is increasingly diagnosed in tropical regions. However, data on risk factors and the geographic epidemiology of the disease are still limited. Previous studies have also largely been based on the analysis of case series data. Here, ...

journal_title：PLoS neglected tropical diseases

authors： Abu Hassan MR,Aziz N,Ismail N,Shafie Z,Mayala B,Donohue RE,Pani SP,Michael E

更新日期：2019-03-18 00:00:00

abstract：:Revealing the dispersal of dengue viruses (DENV) in time and space is central to understanding their epidemiology. However, the processes that shape DENV transmission patterns at the scale of local populations are not well understood, particularly the impact of such factors as human population movement and urbanizatio...

journal_title：PLoS neglected tropical diseases

authors： Rabaa MA,Ty Hang VT,Wills B,Farrar J,Simmons CP,Holmes EC

更新日期：2010-07-27 00:00:00

abstract：:The evolutionary history and age of Plasmodium vivax has been inferred as both recent and ancient by several studies, mainly using mitochondrial genome diversity. Here we address the age of P. vivax on the Indian subcontinent using selectively neutral housekeeping genes and tandem repeat loci. Analysis of ten housekee...

journal_title：PLoS neglected tropical diseases

authors： Prajapati SK,Joshi H,Carlton JM,Rizvi MA

更新日期：2013-09-19 00:00:00

abstract：BACKGROUND:Chagas disease is endemic to the southern Andean region of Ecuador, an area with one of the highest poverty rates in the country. However, few studies have looked into the epidemiology, vectors and transmission risks in this region. In this study we describe the triatomine household infestation in Loja provi...

journal_title：PLoS neglected tropical diseases

authors： Grijalva MJ,Villacis AG,Ocaña-Mayorga S,Yumiseva CA,Moncayo AL,Baus EG

更新日期：2015-10-06 00:00:00

abstract：BACKGROUND:Although leprosy is portrayed as a disappearing disease, leprosy affected persons in India are still suffering massively. Even further, nearly 60% of the world's newly detected cases are appearing from India alone. The problem has exacerbated due to the drastic decrease of global funding after India's offici...

journal_title：PLoS neglected tropical diseases

authors： Jung SH,Han HW,Koh H,Yu SY,Nawa N,Morita A,Ong KIC,Jimba M,Oh J

更新日期：2020-01-13 00:00:00

abstract：BACKGROUND:Hydatidosis is a zoonotic disease of worldwide distribution caused by Echinococcus granulosus. Our study aimed to determine the prevalence of human and canine echinococcosis as well as the associated risk factors in a rural area of the Limarí province in northern Chile. METHODOLOGY/PRINCIPAL FINDINGS:A cros...

journal_title：PLoS neglected tropical diseases

authors： Acosta-Jamett G,Weitzel T,Boufana B,Adones C,Bahamonde A,Abarca K,Craig PS,Reiter-Owona I

更新日期：2014-08-28 00:00:00

abstract：BACKGROUND:During severe (pneumo)sepsis inflammatory and coagulation pathways become activated as part of the host immune response. Thrombomodulin (TM) is involved in a range of host defense mechanisms during infection and plays a pivotal role in activation of protein C (PC) into active protein C (APC). APC has both an...

journal_title：PLoS neglected tropical diseases

authors： Kager LM,Wiersinga WJ,Roelofs JJ,de Boer OJ,Weiler H,van 't Veer C,van der Poll T

更新日期：2014-04-24 00:00:00

abstract：BACKGROUND:Buruli ulcer (BU) is a subcutaneous skin disease listed among the neglected tropical diseases by the World Health Organization (WHO). Early case detection and management is very important to reduce morbidity and the accompanied characteristic disfiguring nature of BU. Since diagnosis based on clinical eviden...

journal_title：PLoS neglected tropical diseases

authors： Sakyi SA,Aboagye SY,Otchere ID,Liao AM,Caltagirone TG,Yeboah-Manu D

更新日期：2016-10-24 00:00:00

abstract：BACKGROUND:Mycobacterium tuberculosis causes the majority of tuberculosis (TB) cases in humans; however, in developing countries, human TB caused by M. bovis may be frequent but undetected. Human TB caused by M. bovis is considered a zoonosis; transmission is mainly through consumption of unpasteurized dairy products, ...

journal_title：PLoS neglected tropical diseases

authors： Bobadilla-del Valle M,Torres-González P,Cervera-Hernández ME,Martínez-Gamboa A,Crabtree-Ramirez B,Chávez-Mazari B,Ortiz-Conchi N,Rodríguez-Cruz L,Cervantes-Sánchez A,Gudiño-Enríquez T,Cinta-Severo C,Sifuentes-Osornio J,Ponce de L

更新日期：2015-09-30 00:00:00

abstract：BACKGROUND:Dengue fever is a major public health concern in many parts of the tropics and subtropics. The first dengue vaccine has already been licensed in six countries. Given the growing interests in the effective use of the vaccine, it is critical to understand the economic burden of dengue fever to guide decision-m...

journal_title：PLoS neglected tropical diseases

authors： Lee JS,Mogasale V,Lim JK,Carabali M,Lee KS,Sirivichayakul C,Dang DA,Palencia-Florez DC,Nguyen THA,Riewpaiboon A,Chanthavanich P,Villar L,Maskery BA,Farlow A

更新日期：2017-10-30 00:00:00

abstract：BACKGROUND:The treatment of Leishmaniasis caused by Leishmania (Viannia) guyanensis is based on a weak strength of evidence from very few clinical trials and some case series reports. Current treatment guidelines recommend pentamidine isethionate or meglumine antimoniate (Glucantime) as the first-line choices. Both are...

journal_title：PLoS neglected tropical diseases

authors： Francesconi VA,Francesconi F,Ramasawmy R,Romero GAS,Alecrim MDGC

更新日期：2018-02-26 00:00:00

abstract：BACKGROUND:Leptospira (L.) interrogans are bacteria responsible for a worldwide reemerging zoonosis. Rodents carry L. interrogans asymptomatically in their kidneys and excrete bacteria in the urine, contaminating the environment. Humans get infected through skin contact and develop a mild or severe leptospirosis that m...

journal_title：PLoS neglected tropical diseases

authors： Fanton d'Andon M,Quellard N,Fernandez B,Ratet G,Lacroix-Lamandé S,Vandewalle A,Boneca IG,Goujon JM,Werts C

更新日期：2014-01-30 00:00:00

abstract：:Isothermal microcalorimetry is an established tool to measure heat flow of physical, chemical or biological processes. The metabolism of viable cells produces heat, and if sufficient cells are present, their heat production can be assessed by this method. In this study, we investigated the heat flow of two medically i...

journal_title：PLoS neglected tropical diseases

authors： Wenzler T,Steinhuber A,Wittlin S,Scheurer C,Brun R,Trampuz A

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:in uganda, control of intestinal schistosomiasis with preventive chemotherapy is typically focused towards treatment of school-aged children; the needs of younger children are presently being investigated as in lakeshore communities very young children can be infected. In the context of future epidemiologica...

journal_title：PLoS neglected tropical diseases

authors： Stothard JR,Sousa-Figueiredo JC,Betson M,Adriko M,Arinaitwe M,Rowell C,Besiyge F,Kabatereine NB

更新日期：2011-01-04 00:00:00

abstract：BACKGROUND:Mycobacterium tuberculosis complex (MTBC), the causative agent of tuberculosis (TB), is composed of eight subspecies. TB in West Africa, in contrast to other geographical regions, is caused by Mycobacterium africanum (MAF) in addition to M. tuberculosis (MTB), with both infections presenting similar symptoms...

journal_title：PLoS neglected tropical diseases

authors： Namasivayam S,Diarra B,Diabate S,Sarro YDS,Kone A,Kone B,Tolofoudie M,Baya B,Diakite MT,Kodio O,Cohen K,Holl J,Achenbach CJ,Chatterjee S,Murphy RL,Bishai W,Diallo S,Sher A,Maiga M

更新日期：2020-05-13 00:00:00

abstract：:Rift Valley fever (RVF), a re-emerging mosquito-borne disease of ruminants and man, was endemic in Africa but spread to Saudi Arabia and Yemen, meaning it could spread even further. Little is known about innate and cell-mediated immunity to RVF virus (RVFV) in ruminants, which is knowledge required for adequate vaccin...

journal_title：PLoS neglected tropical diseases

authors： Nfon CK,Marszal P,Zhang S,Weingartl HM

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:The diagnosis of Human African Trypanosomiasis relies mainly on the Card Agglutination Test for Trypanosomiasis (CATT). While this test is successful, it is acknowledged that there may be room for improvement. Our aim was to develop a prototype lateral flow test based on the detection of antibodies to trypan...

journal_title：PLoS neglected tropical diseases

authors： Sullivan L,Wall SJ,Carrington M,Ferguson MA

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Leptospirosis is often difficult to diagnose because of its nonspecific symptoms. The drawbacks of direct isolation and serological tests have led to the increased development of nucleic acid-based assays, which are more rapid and accurate. A meta-analysis was performed to evaluate the diagnostic accuracy of...

journal_title：PLoS neglected tropical diseases

authors： Lam JY,Low GK,Chee HY

更新日期：2020-02-12 00:00:00

abstract：BACKGROUND:Trachoma prevalence surveys provide the evidence base for district and community-wide implementation of the SAFE strategy, and are used to evaluate the impact of trachoma control interventions. An economic analysis was performed to estimate the cost of trachoma prevalence surveys conducted between 2006 and 2...

journal_title：PLoS neglected tropical diseases

authors： Chen C,Cromwell EA,King JD,Mosher A,Harding-Esch EM,Ngondi JM,Emerson PM

更新日期：2011-03-08 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Hookworm infection is among the major causes of anaemia in poor communities, but its importance in causing maternal anaemia is poorly understood, and this has hampered effective lobbying for the inclusion of anthelmintic treatment in maternal health packages. We sought to review existing evide...

journal_title：PLoS neglected tropical diseases

authors： Brooker S,Hotez PJ,Bundy DA

更新日期：2008-09-17 00:00:00

abstract：:For scientists working on gonochoric organisms, determining sex can be crucial for many biological questions and experimental studies, such as crossbreeding, but it can also be a challenging task, particularly when no sexual dimorphism is visible or cannot be directly observed. In metazoan parasites of the genus Schis...

journal_title：PLoS neglected tropical diseases

authors： Kincaid-Smith J,Boissier J,Allienne JF,Oleaga A,Djuikwo-Teukeng F,Toulza E

更新日期：2016-11-18 00:00:00

abstract：INTRODUCTION:Yaws is endemic in Ghana. The World Health Organization (WHO) has launched a new global eradication campaign based on total community mass treatment with azithromycin. Achieving high coverage of mass treatment will be fundamental to the success of this new strategy; coverage is dependent, in part, on appro...

journal_title：PLoS neglected tropical diseases

authors： Marks M,Kwakye-Maclean C,Doherty R,Adwere P,Aziz Abdulai A,Duah F,Ohene SA,Mitja O,Oguti B,Solomon AW,Mabey DCW,Adu-Sarkodie Y,Asiedu K,Ackumey MM

更新日期：2017-07-31 00:00:00

abstract：BACKGROUND:Blindness is caused by eye pathogens that include a free-living protist (Acanthamoeba castellanii, A. byersi, and/or other Acanthamoeba spp.), a fungus (Fusarium solani), and a bacterium (Chlamydia trachomatis). Hand-eye contact is likely a contributor to the spread of these pathogens, and so hand washing wi...

journal_title：PLoS neglected tropical diseases

authors： Aqeel Y,Rodriguez R,Chatterjee A,Ingalls RR,Samuelson J

更新日期：2017-02-09 00:00:00

abstract：BACKGROUND:MPT64 rapid speciation tests are increasingly being used in diagnosis of tuberculosis (TB). Mycobacterium africanum West Africa 2 (Maf 2) remains an important cause of TB in West Africa and causes one third of disease in The Gambia. Since the introduction of MPT64 antigen tests, a higher than expected rate o...

journal_title：PLoS neglected tropical diseases

authors： Ofori-Anyinam B,Kanuteh F,Agbla SC,Adetifa I,Okoi C,Dolganov G,Schoolnik G,Secka O,Antonio M,de Jong BC,Gehre F

更新日期：2016-07-07 00:00:00

abstract：:Host and parasite gene expression in skin biopsies from Leishmania braziliensis-infected patients were simultaneously analyzed using high throughput RNA-sequencing. Biopsies were taken from 8 patients with early cutaneous leishmaniasis and 17 patients with late cutaneous leishmaniasis. Although parasite DNA was found ...

journal_title：PLoS neglected tropical diseases

authors： Christensen SM,Dillon LA,Carvalho LP,Passos S,Novais FO,Hughitt VK,Beiting DP,Carvalho EM,Scott P,El-Sayed NM,Mosser DM

更新日期：2016-09-15 00:00:00

abstract：:Hand, foot and mouth disease (HFMD) continues to challenge Asia with pandemic potential. In Vietnam, there have been two major outbreaks occurring during 2011-2012 (>200,000 hospitalizations and >200 deaths) and more recently in 2018 (>130,000 hospitalizations and 17 deaths). Given the high burden and the complex epid...

journal_title：PLoS neglected tropical diseases

authors： Nhan LNT,Khanh TH,Hong NTT,Van HMT,Nhu LNT,Ny NTH,Nguyet LA,Thanh TT,Anh NT,Hang VTT,Qui PT,Viet HL,Tung TH,Ha DQ,Tuan HM,Thwaites G,Chau NVV,Thwaites L,Hung NT,van Doorn HR,Tan LV

更新日期：2020-08-17 00:00:00