Resveratrol Improves Endothelial Progenitor Cell Function through miR-138 by Targeting Focal Adhesion Kinase (FAK) and Promotes Thrombus Resolution In Vivo.

abstract：BACKGROUND:It is widely accepted that patients with ovarian cancer relapsing 6 to 12 months after completion of a platinum-based regimen are considered to be partially platinum-sensitive. The aim of this study was to evaluate and correlate the efficacy and toxicity of reinduction with paclitaxel-carboplatin in a platin...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Milović-Kovačević M,Stamatovic L,Popov I,Radošević-Jelić L,Kezic I

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:Current biological investigations tend to operate with genomes, instead of genes as during the last century. It is possible to compare entire genomes, transcriptomes or proteomes, using alphanumeric data corresponding to the differential expression levels of thousands of genes. What remains difficult is to l...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Rihn BH,Vidal S,Nemurat C,Vachenc S,Mohr S,Mazur F,Houdry P,Grandjean F,Visvikis S,Ducloy J

更新日期：2003-08-01 00:00:00

abstract：:Dopamine receptors control neural signals that modulates behavior. Dopamine plays an important role in normal attention; that is the reason for studying the genes of the dopaminergic system, mainly in connection with disorders of attention. DRD4 influences the postsynaptic action of dopamine and is implicated in many ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Ptácek R,Kuzelová H,Stefano GB

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to investigate the values of contrast-enhanced ultrasound (CEUS) in the diagnosis and differential diagnosis of hyperechoic liver lesions. MATERIAL AND METHODS:The CEUS findings of 102 patients with hyperechoic liver lesions identified by 2-dimensional ultrasound in the Affilia...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Liu J,Wang D,Li H,Li H,Zhou T,Zhao S,Ding Z

更新日期：2015-09-22 00:00:00

abstract：BACKGROUND:It is well established that there is a reduction in the skin blood flow (SBF) in response to heat with age and diabetes. While it is known that high BMI creates a stress on the cardiovascular system and increases the risk of all cause of morbidity and mortality, little is known of the effect of high BMI on S...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Petrofsky JS,Alshammari F,Bains GS,Khowailed IA,Lee H,Kuderu YN,Lodha RD,Rodrigues S,Nguyen D,Potnis PA,Deshpande PP,Yim JE,Berk L

更新日期：2013-04-10 00:00:00

abstract：BACKGROUND:Insulin-like growth factor-I (IGF-I) is probably involved in promoting both normal and neoplastic cell growth, neoplastic transformation processes, angiogenesis, and neoplasma progression. On the other hand, one possible mechanism of the oncostatic action of melatonin is its influence on the action and/or re...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Kajdaniuk D,Marek B,Kos-Kudła B,Zwirska-Korczala K,Ostrowska Z,Buntner B,Szymszal J

更新日期：2002-06-01 00:00:00

abstract：:BACKGROUND Virtual reality (VR) training with motion-controlled console games can be incorporated into stroke rehabilitation programs. The use of a variety of gaming software can provide the patient with an opportunity to perform activities that are exciting, entertaining, and that may not be feasible in clinical envi...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Lee MM,Lee KJ,Song CH

更新日期：2018-04-27 00:00:00

abstract：BACKGROUND:The aim of this cross-sectional study was to examine the relationship between obesity and lipid markers. MATERIAL AND METHODS:We divided 66 non-diabetic adult obese patients (mean age: 55.8±11.6 years) into 3 groups according to body mass index (BMI). All patients were measured for waist circumference (WC),...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Stępień A,Stępień M,Wlazeł RN,Paradowski M,Banach M,Rysz J

更新日期：2014-12-16 00:00:00

abstract：:BACKGROUND In this study we investigated changes in the status of antibiotic use in Tianjin since the implementation of the Antibiotic Stewardship Program (ASP) (2011-2013), as well as existing problems, strategies, and outcomes to promote rational clinical antibiotic use. MATERIAL AND METHODS A quasi-experimental stu...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhang HH,Du Y,Liu W,Song SD,Zhao W,Huang GW,Wang HS

更新日期：2017-02-09 00:00:00

abstract：:BACKGROUND Golgi phosphoprotein 3 (GOLPH3) has been reported to be involved in the development of several human cancers. Our previous study showed that GOLPH3 expression in glioma tissues was related to the severity of the malignancy of the cancer. However, the mechanism by which GOLPH3 affects cell apoptosis is large...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Li X,Li M,Tian X,Li Q,Lu Q,Jia Q,Zhang L,Yan J,Li X,Li X

更新日期：2016-10-04 00:00:00

abstract：:BACKGROUND Aminoglycosides, a type of gram-negative antibacterial, are broad-spectrum antibiotics that are highly potent and have satisfactory therapeutic efficacy in the treatment of life-threatening infections. Our study aimed to establish a gentamicin-induced cochlear injury model and to investigate the cochlear ne...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Wang F,Gong S,Zhou Y,Huang C,Li T,Li Q,Ceng X,Wang C

更新日期：2018-12-28 00:00:00

abstract：:BACKGROUND Collapsin response mediator protein-2 (CRMP-2) is the first member of the CRMP family that has been identified in primary neuronal cells; it was originally found and identified in the regulation of microtubule dimerization into microtubules. MATERIAL AND METHODS In the present study, we aimed to investigate...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： He J,Zhu J

更新日期：2018-07-18 00:00:00

abstract：BACKGROUND:An emerging body of literature has recently defined a reduced risk of cancer following the use of nonsteroidal anti-inflammatory drugs (NSAIDs), which are generally able to exert an apoptotic property and inhibitory effects on the activity and/or expression of matrix metalloproteinases (MMPs). This study was...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Mirshafiey A,Khorramizadeh MR,Saadat F,Rehm BH

更新日期：2004-10-01 00:00:00

abstract：:BACKGROUND Pulsed radiofrequency of genicular nerves in the management of osteoarthritis related chronic knee pain has recently become a promising treatment. Ultrasonography has replaced fluoroscopic guidance in pain medicine. The aim of this study was to investigate the effect of ultrasound-guided genicular pulsed ra...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Erdem Y,Sir E

更新日期：2019-03-12 00:00:00

abstract：BACKGROUND:Our objective was to determine whether adenosine-induced ischemia exerts a delayed cardiac protective effect in patients with stable effort angina ischemic heart disease. MATERIAL/METHODS:The study group was comprised of 32 patients (men) with symptoms of stable effort angina, aged 38-65 years (Group 1), an...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Gawor Z,Granosik A,Grabowicz W,Piotrowski G,Grycewicz T,Goch A,Markuszewski L,Goch JH

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:Active immunization techniques against exogenous source antigens (ags - such as bacteria, virus) proved to be successful in preventing many acute infectious diseases from occurring in a susceptible population. However, an active immunization technique that could be employed both prophylactically and therapeu...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Barabas AZ,Cole CD,Kovacs ZB,Lafreniere R

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Acetylcholine and bradykinin cause endothelium-dependent hyperpolarization and relaxation of vascular smooth muscle. These responses are mediated in part by an endothelium-derived hyperpolarizing factor (EDHF). Epoxyeicosatrienoic acids (EETs) are cytochrome P450 metabolites of arachidonic acid and appear to...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Campbell WB,Falck JR,Gauthier K

更新日期：2001-07-01 00:00:00

abstract：:BACKGROUND Alzheimer disease (AD) is a significant health issue for the elderly, and there are at present no clinically effective anti-AD agents. Prevention of Aß-induced neurotoxicity is proposed as a possible modality for treatment of AD. miR-33 has been proven to promote Aß secretion and impair Aß clearance in neur...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Wang X,Li X,Huang B,Yang L,Chen K,Zhao D,Luo X,Wang Y

更新日期：2020-03-02 00:00:00

abstract：:BACKGROUND As a common malignant tumor, gastric carcinoma requires early diagnosis to improve treatment efficacy. MicroRNA (miR) molecules have highly conserved nucleotide sequences and can negatively regulate target gene expression at the translational level. miR-421 has been suggested to be related with gastric canc...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Jin X,Yu N

更新日期：2016-05-02 00:00:00

abstract：BACKGROUND:We compared cardiac electrophysiological indicators and regional expression levels of cardiac hyperpolarization-activated cyclic nucleotide-gated (HCN) channels between adult and aged dogs to identify possible mechanisms of age-related atrial fibrillation. MATERIAL/METHODS:Corrected sinus node recovery time...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Li YD,Hong YF,Zhang Y,Zhou XH,Ji YT,Li HL,Hu GJ,Li JX,Sun L,Zhang JH,Xin Q,Yusufuaji Y,Xiong J,Tang BP

更新日期：2014-11-14 00:00:00

abstract：:BACKGROUND The purpose of this study was to explore the function and mechanism of peroxisome proliferator activated receptor agonist (PPARγ) in the toll-like receptor 2 (TLR2)/nod-like receptor with pyrin domain containing 3 (NLRP3) inflammatory corpuscle pathway of asthmatic mice. MATERIAL AND METHODS Eighteen female...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Cheng Y,Li S,Wang M,Cheng C,Liu R

更新日期：2018-12-13 00:00:00

abstract：BACKGROUND:Although the temporalis fascia has been widely used since 1957as a graft in tympanoplasty, it can eventually become thin and atrophic. In addition, due to the lack of elasticity and resistance to pressure changes in the external ear canal, secondary perforations may also develop. Therefore, several authors h...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Ferekidis EA,Nikolopoulos TP,Kandiloros DC,Ferekidou EE,Yiotakis JE,Tsangaroulakis A,Adamopoulos GK

更新日期：2003-02-01 00:00:00

abstract：:BACKGROUND The present study aimed to investigate the clinical relevance of fragile histidine triad protein (FHIT) in patients with bladder cancer (BC). MATERIAL AND METHODS Three independent BC microarray studies were collected and reanalyzed. The expression of FHIT was evaluated between BC samples and normal bladder...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Liu XP,Yin XH,Yan XH,Zeng XT,Wang XH

更新日期：2018-05-12 00:00:00

abstract：:BACKGROUND Therapeutic evaluation of 3-dimensional conformal radiotherapy (3DCRT) is rarely reported for non-resectable hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT). The aim of this study was to determine the value of contrast-enhanced ultrasound (CEUS) in evaluating the therapeutic response o...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Li H,Liu J,Chen M,Li H,Long L

更新日期：2018-11-14 00:00:00

abstract：BACKGROUND:Autism is a heterogeneous pervasive developmental disorder with a poorly defined aetiology and pathophysiology. There are indications that the incidence of the disease is rising but still no definitive diagnostic biochemical markers have been isolated. Here we have addressed the hypothesis that urinary level...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Bull G,Shattock P,Whiteley P,Anderson R,Groundwater PW,Lough JW,Lees G

更新日期：2003-10-01 00:00:00

abstract：:BACKGROUND The aim of this study was to detect the expression of epidermal growth factor-containing fibulin-like extracellular matrix protein 1 (EFEMP1) and estimate its diagnostic value in prostate cancer (PCa). MATERIAL AND METHODS EFEMP1 expression in serum and urine of patients with PCa, benign controls and health...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Shen H,Zhang L,Zhou J,Chen Z,Yang G,Liao Y,Zhu M

更新日期：2017-01-13 00:00:00

abstract：:The anterior transpedicular screws (ATPS) fixation is a valuable discovery in the field of lower cervical spine (LCS) reconstruction, as it has the advantages of both anterior and posterior approaches. In recent years, with in-depth research on ATPS fixation related to anatomy, biomechanical tests, and clinical applic...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhang YW,Zeng T,Gao WC,Xiao X,Xiao Y,Chen X,Zhang SL,Deng L

更新日期：2019-08-21 00:00:00

abstract：:So far the treatment of chronic hepatitis B has been based on the use of numerous agents, particularly interferon alpha which proved the most effective. Attempts are made to introduce new therapeutic methods (antiviral agents--nucleoside analogues, immunotherapy--anti HBV vaccine, gene therapy) in order to obtain high...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Lebensztejn DM,Kaczmarski M

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:The aim of this study was to determine whether eyebrow and eyelash whitening is an effective parameter in age estimation. MATERIAL AND METHODS:We evaluated 1545 patients. Age groups were 1-10, 11-20, 21-30, 31-40, 41-50, 51-60, 61-70, 71-80, and 81-90 years. Level of whitening was categorized as level 0: no...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Kantarcı FA,Kantarcı MN,Bilgi S

更新日期：2014-01-22 00:00:00

abstract：:BACKGROUND Calcium overload, inflammation, and apoptosis play important roles in myocardial ischemia-reperfusion injury (MIRI). Gastrodin pretreatment can alleviate MIRI. This study observed sarcoplasmic reticulum calcium transport ATPase (Ca2+-ATPase, SERCA) and calcium phosphate (PLB) protein expression in the ventr...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Li Y,Wang X,Lou C

更新日期：2016-09-19 00:00:00