Collapsin Response Mediator Protein-2 Ameliorates Sevoflurane-Mediated Neurocyte Injury by Targeting PI3K-mTOR-S6K Pathway.

abstract：:The methods of increasing the efficacy of thrombolysis under clinical and experimental conditions are have been discussed in the light of analysis of current tendencies in the investigation and development of thrombolytic and adjunctive therapy. Analysis of the data obtained in the search for novel plasminogen activat...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Maksimenko AV

更新日期：2002-01-01 00:00:00

abstract：:BACKGROUND The serine peptidase inhibitor Kazal type 13 (SPINK13) gene has tumor suppressor activity, but its role in renal cell carcinoma (RCC) remains unknown. This study aimed to investigate mRNA expression of SPINK13 in clear cell renal cell carcinoma (CCRCC) in human tissue and to use bioinformatics data to inves...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Xu WH,Shi SN,Wang J,Xu Y,Tian X,Wan FN,Cao DL,Qu YY,Zhang HL,Ye DW

更新日期：2019-12-11 00:00:00

abstract：:The Fig 4C and 4D are the same, but the author showed them as two parallel groups. Reference: Cardioprotective Effect of Isosorbide Dinitrate Postconditioning Against Rat Myocardial Ischemia-Reperfusion Injury In Vivo Xinwen Zhao, Mengjuan Wang, Mei Li, Na Wu, Dalin Song Med Sci Monit 2019;25: 1629-1636 10.12659/MSM.9...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhao X,Wang M,Li M,Wu N,Song D

更新日期：2019-08-26 00:00:00

abstract：BACKGROUND:The aim of the present study was to assess the impact of reversible myocardial ischemia, provoked by acute physical activity during an exercise stress echocardiography (ESE), on nitric oxide (NOx) and asymmetric dimethylarginine (ADMA) production in patients with high risk for coronary heart disease (CHD). ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Ilic MD,Ilic S,Lazarevic G,Kocic G,Pavlovic R,Stefanovic V

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Despite the wide application of open reduction and internal fixation with locking plates for the treatment of proximal humeral fractures, the surgical invasive approach remains controversial. This study aimed to evaluate the pros and cons of the minimally invasive lateral approach for the treatment of proxim...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Liu K,Liu PC,Liu R,Wu X

更新日期：2015-02-15 00:00:00

abstract：BACKGROUND:The goal of this prognostic study was to investigate whether the duration of untreated psychosis (DUP) may have a prognostic value with regard to the further course of the illness. MATERIAL/METHODS:Fifty-eight patients (77% of the original study group) diagnosed with DSM III schizophrenia and later re-diagn...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Cechnicki A,Hanuszkiewicz I,Polczyk R,Bielańska A

更新日期：2011-05-01 00:00:00

abstract：:BACKGROUND This study was performed with the aim to explore the expression of high-mobility group protein B1 (HMGB1) and the receptor for advanced glycation end-product (RAGE) in knee osteoarthritis (KOA) and its clinical significance. MATERIAL AND METHODS A total of 108 synovial tissues selected from KOA patients wer...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Sun XH,Liu Y,Han Y,Wang J

更新日期：2016-06-20 00:00:00

abstract：:BACKGROUND The aim of this study was to assess the effects of interleukin-1 (IL-1) receptor associated kinase (IRAK) inhibitors on intestinal injury induced by necrotizing enterocolitis (NEC) in neonatal rats and its regulation on the intestinal Toll-like receptor (TLR) inflammatory signaling pathway. MATERIAL AND MET...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Hou Y,Lu X,Zhang Y

更新日期：2018-05-22 00:00:00

abstract：:BACKGROUND Oxidative DNA damage is associated with male infertility. The aim of this study was to evaluate the oxidative DNA damage of sperm cells and blood leukocytes and to determine the levels of MDA and NO levels in seminal and blood plasma of idiopathic infertile men. MATERIAL AND METHODS The study enrolled 52 pa...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Taken K,Alp HH,Eryilmaz R,Donmez MI,Demir M,Gunes M,Aslan R,Sekeroglu MR

更新日期：2016-11-11 00:00:00

abstract：INTRODUCTION:As numerous papers have presented many disturbances of blood lipid composition and changes in lipolytic enzyme activity, it was considered appropriate to investigate the postheparin lipolytic activity in serum of psoriatic males. The course of serum lipolytic process provoked by intravenous application of ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Pietrzak A,Lecewicz-Toruń B,Borzecki A

更新日期：2000-07-01 00:00:00

abstract：INTRODUCTION:Tumors arising in the lungs are in over 90% bronchogenic carcinomas that have been attributed predominantly to tobacco smoking, asbestos or air pollution but little is known about endogenous factors that could facilitate their development and invasiveness. The lungs originate embryologically from the same ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Gocyk W,Nikliński T,Olechnowicz H,Duda A,Bielański W,Konturek PC,Konturek SJ

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:The aim was to assess the effect of trimetazidine (TMZ) on mitochondrial alterations induced in a canine model of brief, repeated episodes of ischemia. MATERIAL/METHODS:Twelve crossbred dogs were analyzed, after double-blind randomization, to a 7-day treatment with either TMZ or placebo. Twenty brief, compl...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Morillas Blasco PJ,Hernándiz Martinez A,Azorín Villena I,Portolés Sanz M,Pallarés Carratala V,Martinez VB,Capdevilla Carbonell C,Aguilar Llopis A,Cosín Aguilar J

更新日期：2005-06-01 00:00:00

abstract：:BACKGROUND Recently, miR-146a C>G, miR- 149 T>C, miR-196a2 T>C and miR-499 A>G polymorphisms have been associated with susceptibility to many diseases, including ischemic stroke (IS). However, results have been reported inconsistency in IS, especially in the Chinese population. This study aimed to investigate the poly...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhu X,Hou R,Ma A,Yang S,Pan X

更新日期：2018-10-15 00:00:00

abstract：:BACKGROUND Superficial femoral artery chronic total occlusion (SCTO) is a common type of peripheral arterial disease (PAD). Endovascular therapy is a treatment approach that has a poor long-term success rate in this group. The aim of this study was to compare the mid-term results of two different uses of nitinol stent...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Bildirici U,Aktas M,Dervis E,Celikyurt U

更新日期：2017-06-26 00:00:00

abstract：BACKGROUND:The prevalence of type 2 diabetes mellitus is rapidly increasing, worldwide and also in Hungary. Timely diagnosis and early treatment could be aided by targeted screening. Recognizing this, the Hungarian Diabetes Association initiated a risk-stratified screening with the involvement of primary care physician...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Winkler G,Hídvégi T,Vándorfi G,Balogh S,Jermendy G

更新日期：2013-01-24 00:00:00

abstract：BACKGROUND:It has been suggested that adherence to a Mediterranean diet reduces all causes of mortality, especially death rates due to coronary heart disease. In this review we summarize the findings of observational studies that evaluated the effect of the Mediterranean dietary pattern in the primary and secondary pre...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Panagiotakos DB,Pitsavos C,Polychronopoulos E,Chrysohoou C,Zampelas A,Trichopoulou A

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:Contrast-induced nephropathy (CIN) refers to acute renal damage that occurs after the use of contrast agents. This study investigated the renal protective effect of probucol in a rat model of contrast-induced nephropathy and the mechanism of its effect. MATERIAL AND METHODS:Twenty-eight Wistar rats were ran...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Wang N,Wei RB,Li QP,Yang X,Li P,Huang MJ,Wang R,Cai GY,Chen XM

更新日期：2015-09-26 00:00:00

abstract：BACKGROUND:The role of physical activity in a health-seeking life style is increasingly and frequently about the improvement of one's silhouette. This constitutes the problem that we are trying to resolve in this article--are physical activities a part of actions aimed at the reduction of weight in people trying to los...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Lipowski M,Buliński L,Krawczyński M

更新日期：2009-08-01 00:00:00

abstract：:BACKGROUND Adenomyosis is a cause of chronic pelvic pain in women of reproductive age. The aim of this study was to investigate the effects of subcutaneous etonogestrel implantation on adenomyosis. MATERIAL AND METHODS A clinical observational study included 17 women with adenomyosis who were treated with subcutaneous...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Wu J,Huang Y,Chen L,Hu J,Zou Y

更新日期：2018-09-01 00:00:00

abstract：:BACKGROUND The downregulation of tropomyosin 1 (TPM1) has been observed in various tumors, but few studies have focused on the clinical significance of TPM1 in intrahepatic cholangiocarcinoma (ICC). In the present study, we investigated the prognostic significance of TPM1 in ICC. MATERIAL AND METHODS A total of 124 pa...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Chen Y,Hong Z,Lu S,Zhang N,Rong G,Chang X,Liu Z,Bai W,Dong Z,Gao X,Zeng Z,Lu Y

更新日期：2018-11-03 00:00:00

abstract：:BACKGROUND Different blood pressure targets should be formulated for different groups of people. This study aimed to assess the effectiveness of intensive blood control in improving the carotid morphology and hemodynamics in Chinese patients with hyperhomocysteinemia-type hypertension and high risk of stroke. MATERIAL...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Wu W,Liu J,Li A,Li J,Yang Y,Ye X,Zheng J

更新日期：2019-08-01 00:00:00

abstract：:BACKGROUND Gastric cancer (GC) is a life-threating malignancy worldwide. Accumulating studies suggest propofol has anti-tumor functions in addition to the anesthetic effect. This study aimed to figure out the effects of propofol treatment in GC development. MATERIAL AND METHODS Human GC SGC-7901 and NCI-N87 cells were...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Liu F,Qiu F,Fu M,Chen H,Wang H

更新日期：2020-03-02 00:00:00

abstract：:BACKGROUND The imbalance between bone resorption and formation is the basic mechanism underlying osteoporosis in the elderly. Osteogenesis is the differentiation of human mesenchymal stem cells (hMSCs) into osteoblasts. Sirtuin6 (SIRT6) regulates various biological functions, including differentiation. Transient recep...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Xiao F,Zhou Y,Liu Y,Xie M,Guo G

更新日期：2019-11-08 00:00:00

abstract：BACKGROUND:We used an animal model of experimental varicocele to investigate the effects on the ipsilateral testis during the progression of experimental varicocele in rat. MATERIAL/METHODS:Experimental varicocele was induced by partial ligation of the left renal vein in rats. Rats in each control group were subjected...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zheng Y,Zhang X,Zhou J,Cheng F,Zhou B

更新日期：2008-06-01 00:00:00

abstract：:BACKGROUND The aim of this study was to compare the clinical safety and effectiveness of transurethral bipolar plasmakinetic enucleation of the prostate (PKEP) vs. transurethral bipolar plasmakinetic resection of the prostate (PKRP) in the treatment of benign prostate hyperplasia (BPH) more than 80 ml. MATERIAL AND ME...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Jiang Y,Bai X,Zhang X,Wang M,Tian J,Mu L,Zhang N,Li M,Du Y

更新日期：2020-04-27 00:00:00

abstract：:BACKGROUND The efficacy of a beta-blocker or statin alone versus combination therapy is uncertain. We compared the effects of a combination of beta-blocker and statin with those of one-drug therapies with regard to the occurrence of a major adverse cardiovascular event (MACE) in patients with acute coronary syndrome (...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhu L,Cui Q,Liu Y,Liu Z,Zhang Y,Liu F,Wang J

更新日期：2020-08-18 00:00:00

abstract：:BACKGROUND In recent years, the incidence of gastric cancer (GC) has been increasing worldwide. Emerging evidence shows that microRNAs (miRs) may be involved in the pathogenesis of GC. Thus, this study explored the mediatory role of miR-495 in GC chemosensitivity, and investigated the mechanism by which it affects the...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Li N,Han M,Zhou N,Tang Y,Tang XS

更新日期：2018-08-27 00:00:00

abstract：:BACKGROUND We studied the effect of APOBEC3G on persistent human papillomavirus (HPV) infection and the correlation between APOBEC3G polymorphism and HPV persistent infection and cervical disease progression in Uygur women in China. MATERIAL AND METHODS From January 2015 to December 2017, we enrolled 529 Uygur ethnic ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Sui S,Chen H,Han L,Wang L,Niyazi M,Zhu K

更新日期：2019-09-17 00:00:00

abstract：:BACKGROUND Chronic spinal cord injury (CSCI) is a worldwide clinical problem. We aimed to reveal differentially expressed (DE) lncRNAs and to find associated pathways that may function as targets for CSCI therapy. MATERIAL AND METHODS After a CSCI rat model was confirmed by the Basso Beattie Bresnahan (BBB) scale and ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhang L,Yang L,Li W,Yang Y,Sun W,Gong P,Wang L,Wang K

更新日期：2018-11-09 00:00:00

abstract：BACKGROUND:Benzodiazepine binding sites distinct from the GABA-receptor-chloride-complex in the central nervous system have been recognized in many peripheral tissues, but their physiological role remains unexplained. Our study was undertaken to examine the effects of diazepam, clonazepam, and PK 11195, a peripheral be...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Rajtar G,Zółkowska D,Kleinrok Z

更新日期：2002-04-01 00:00:00