Fatty Infiltration of the Myocardium and Arrhythmogenesis: Potential Cellular and Molecular Mechanisms.

abstract：:Endothelial dysfunction has been considered as pivotal in the pathogenesis of decompression sickness (DCS) and contributes substantively to subsequent inflammatory responses. Escin is well known for its endothelial protection and anti-inflammatory properties, and its protection against DCS has been proved in a rat mod...

journal_title：Frontiers in physiology

authors： Qing L,Meng W,Zhang W,Yi HJ,Zhang K,Ariyadewa DK,Xu WG

更新日期：2019-05-21 00:00:00

abstract：:Exhaled breath carbon monoxide (eCO) is a candidate biomarker for non-invasive assessment of oxidative stress and respiratory diseases. Standard end-tidal CO analysis, however, cannot distinguish, whether eCO reflects endogenous CO production, lung diffusion properties or exogenous sources, and is unable to resolve a ...

journal_title：Frontiers in physiology

authors： Ghorbani R,Blomberg A,Schmidt FM

更新日期：2018-07-30 00:00:00

abstract：:Abnormal flow patterns in the aortas of those with bicuspid aortic valves (BAVs) are increasingly recognized as important in the pathogenesis of aortic dilatation but pulmonary flow patterns in bicuspid pulmonary valves have not been studied. Bicuspid pulmonary valve disease is rare and a small numbers of case reports...

journal_title：Frontiers in physiology

authors： Bissell MM,Loudon M,Neubauer S,Myerson SG

更新日期：2017-05-31 00:00:00

abstract：:The aim of this study was to analyze the relationship between alveolar bone deformation and β-catenin expression levels in response to the mechanical load changed by dental extraction in adult rats. Twenty-four male rats (Rattus norvegicus albinus), Wistar linage, at 2 months of age, were used. The right upper incisor...

journal_title：Frontiers in physiology

authors： Ferreira BC,Freire AR,Araujo R,do Amaral-Silva GK,Okamoto R,Prado FB,Rossi AC

更新日期：2020-06-05 00:00:00

abstract：:Aim: The current study aimed to examine the effects of resistance exercise with concomitant consumption of high vs. low daily doses of non-steroidal anti-inflammatory drugs (NSAIDs) on mitochondrial oxidative phosphorylation in skeletal muscle. As a secondary aim, we compared the effects of eccentric overload with con...

journal_title：Frontiers in physiology

authors： Cardinale DA,Lilja M,Mandić M,Gustafsson T,Larsen FJ,Lundberg TR

更新日期：2017-12-19 00:00:00

abstract：:Significant progress has been made in the last decade in the development of optogenetic effectors and sensors that can be deployed to understand complex biological signaling in mammals at a molecular level, without disrupting the distributed, lineage specific signaling circuits that comprise nuanced physiological resp...

journal_title：Frontiers in physiology

authors： Shui B,Lee JC,Reining S,Lee FK,Kotlikoff MI

更新日期：2014-11-06 00:00:00

abstract：:Xinnao shutong (XNST) capsules have been clinically used in China to treat cerebrovascular diseases. Previous studies have demonstrated that XNST has significant neuroprotective effects against acute cerebral ischemic stroke. The present study investigated the effects and mechanisms of XNST treatment following chronic...

journal_title：Frontiers in physiology

authors： Wang L,Wang R,Chen Z,Zhao H,Luo Y

更新日期：2018-05-15 00:00:00

abstract：:Sleep apnea/hypopnea disorders include centrally originated diseases and obstructive sleep apnea (OSA). This last condition is renowned as a frequent secondary cause of hypertension (HT). The mechanisms involved in the pathogenesis of HT can be summarized in relation to two main pathways: sympathetic nervous system st...

journal_title：Frontiers in physiology

authors： Diogo LN,Monteiro EC

更新日期：2014-09-22 00:00:00

abstract：:Signaling pathways of red blood cells' (RBCs) micromechanics regulation, which are responsible for maintaining microcirculation, constitute an important property of RBC physiology. Selective control over these processes may serve as an indispensable tool for correction of hemorheological disorders, which accompany a n...

journal_title：Frontiers in physiology

authors： Semenov AN,Shirshin EA,Muravyov AV,Priezzhev AV

更新日期：2019-08-14 00:00:00

abstract：:Hypertrophic cardiomyopathy (HCM) is the most common mendelian heart disease, with a prevalence of 1/500. HCM is a primary cause of sudden death, due to an heightened risk of ventricular tachyarrhythmias that often occur in young asymptomatic patients. HCM can slowly progress toward heart failure, either with preserve...

journal_title：Frontiers in physiology

authors： Coppini R,Ferrantini C,Mugelli A,Poggesi C,Cerbai E

更新日期：2018-10-16 00:00:00

abstract：:Elderly healthy individuals have a reduced exercise tolerance and a decreased left ventricle inotropic reserve related to increased vascular afterload, arterial-ventricular load mismatching, physical deconditioning and impaired autonomic regulation (the so called "β-adrenergic desensitization"). Adrenergic responsiven...

journal_title：Frontiers in physiology

authors： Ferrara N,Komici K,Corbi G,Pagano G,Furgi G,Rengo C,Femminella GD,Leosco D,Bonaduce D

更新日期：2014-01-09 00:00:00

abstract：Aim:Guanidinoacetate N-methyltransferase (GAMT) is the second essential enzyme in creatine (Cr) biosynthesis. Short-term Cr deficiency is metabolically well tolerated as GAMT-/- mice exhibit normal exercise capacity and response to ischemic heart failure. However, we hypothesized long-term consequences of Cr deficiency...

journal_title：Frontiers in physiology

authors： Aksentijević D,Zervou S,Eykyn TR,McAndrew DJ,Wallis J,Schneider JE,Neubauer S,Lygate CA

更新日期：2020-01-21 00:00:00

abstract：:Tumor necrosis factor (TNF)-α, a major part in inflammatory, infectious and tumor processes, and is pivotal at the early stages of gastric cancer. Relationship between its risk and TNF-α rs361525 polymorphism has been demonstrated, but remains conflicting and controversial. Therefore, a meta-analysis was conducted to ...

journal_title：Frontiers in physiology

authors： Xu T,Kong Z,Zhao H

更新日期：2018-05-15 00:00:00

abstract：:Aim: Combined use of herbal medicines in patients underwent dual antiplatelet therapy (DAPT) might cause bleeding or thrombosis because herbal medicines with anti-platelet activities may exhibit interactions with DAPT. In this study, we tried to use a feedback system control (FSC) optimization technique to optimize do...

journal_title：Frontiers in physiology

authors： Liu W,Li YL,Feng MT,Zhao YW,Ding X,He B,Liu X

更新日期：2018-05-04 00:00:00

abstract：:Corpus luteum (CL) is a transient endocrine tissue that produces progesterone for maintaining pregnancy in mammals. In addition, the regression of CL is necessary for the initiation of the estrous cycle. Extensive research has shown that the prostaglandin F2α (PGF2α) induces the regression of CL in ruminants. However,...

journal_title：Frontiers in physiology

authors： Wen X,Liu L,Li S,Lin P,Chen H,Zhou D,Tang K,Wang A,Jin Y

更新日期：2020-09-11 00:00:00

abstract：:Animal studies have shown that very early life events may have programing effects on adult metabolism and health. In this study, we aim, for the first, time to elucidate the effects of embryonic thermal manipulation (TM) on the performance of overfed mule ducks, in particular for the production of foie gras (fatty liv...

journal_title：Frontiers in physiology

authors： Massimino W,Davail S,Bernadet MD,Pioche T,Tavernier A,Ricaud K,Gontier K,Bonnefont C,Manse H,Morisson M,Fauconneau B,Collin A,Panserat S,Houssier M

更新日期：2019-12-12 00:00:00

abstract：:Global environmental change is leading to an increase in the frequency, intensity, and duration of extreme weather events, so effective environmental management requires an understanding not only of the physiological response of organisms to increased mean temperatures, but also to extreme environmental conditions. To...

journal_title：Frontiers in physiology

authors： Cooper CE,Withers PC,Hurley LL,Griffith SC

更新日期：2019-11-20 00:00:00

abstract：:Background: The superior cervical ganglion (SCG) of the autonomic nervous system plays an important role in different cardiovascular diseases. In this study, we investigated the effects of ischemia and fluvastatin treatment on the ion channel characteristics of SCG neurons in a rabbit myocardial ischemia (MI) model. M...

journal_title：Frontiers in physiology

authors： Cheng L,Wang X,Liu T,Tse G,Fu H,Li G

更新日期：2018-09-10 00:00:00

abstract：:Muscle strain is one of the most frequent sports injuries, having the rectus femoris (RF) muscle as the reported preferred site of quadriceps muscle strain. The decrease muscle stiffness could be an effective RF muscle strain prevention. In recent studies, a high-intensity static stretching intervention decreased pass...

journal_title：Frontiers in physiology

authors： Nakamura M,Sato S,Murakami Y,Kiyono R,Yahata K,Sanuki F,Yoshida R,Fukaya T,Takeuchi K

更新日期：2021-01-13 00:00:00

abstract：:Severely affected patients with autonomic failure require pressor agents to counteract the blood pressure fall and improve presyncopal symptoms upon standing. Previous studies suggest that combination ergotamine and caffeine may be effective in the treatment of autonomic failure, but the efficacy of this drug has not ...

journal_title：Frontiers in physiology

authors： Arnold AC,Ramirez CE,Choi L,Okamoto LE,Gamboa A,Diedrich A,Raj SR,Robertson D,Biaggioni I,Shibao CA

更新日期：2014-07-24 00:00:00

abstract：:The underlying mechanisms in the development of diabetic nephropathy are currently unclear and likely consist of a series of dynamic events from the early to late stages of the disease. Diabetic nephropathy is currently without curative treatments and it is acknowledged that even the earliest clinical manifestation of...

journal_title：Frontiers in physiology

authors： Schiffer TA,Friederich-Persson M

更新日期：2017-04-11 00:00:00

abstract：:Pinocembrin (PIN) is a natural flavonoid widely found in bee propolis with potent gastrointestinal protective effects. In consequence, PIN has great potential in preventing inflammatory bowel diseases (IBDs) while scant information is available. In this study, a dextran sulfate sodium (DSS)-induced rats ulcerative col...

journal_title：Frontiers in physiology

authors： Hu L,Wu C,Zhang Z,Liu M,Maruthi Prasad E,Chen Y,Wang K

更新日期：2019-07-19 00:00:00

abstract：:Background: For some time now, the effects of sound, noise, and music on the human body have been studied. However, despite research done through time, it is still not completely clear what influence, interaction, and effects sounds have on human body. That is why it is necessary to conduct new research on this topic....

journal_title：Frontiers in physiology

authors： Idrobo-Ávila EH,Loaiza-Correa H,van Noorden L,Muñoz-Bolaños FG,Vargas-Cañas R

更新日期：2018-05-22 00:00:00

abstract：:As a biomaterial, chitosan has been widely used in tissue engineering, wound healing, drug delivery, and other biomedical applications. It can be formulated in a variety of forms, such as powder, film, sphere, gel, and fiber. These features make chitosan an almost ideal biomaterial in cell culture applications, and ce...

journal_title：Frontiers in physiology

authors： Gao W,Lai JC,Leung SW

更新日期：2012-08-21 00:00:00

abstract：:Telomeres are genomic complex at the end of chromosomes that protects the DNA and telomere length (TL) is related to several age-related diseases, lifespan, and cancer. On the other hand, cancer is a multifactorial disease that is responsible for reduce the quality of life and kills millions of people every year. Both...

journal_title：Frontiers in physiology

authors： Nomikos NN,Nikolaidis PT,Sousa CV,Papalois AE,Rosemann T,Knechtle B

更新日期：2018-12-18 00:00:00

abstract：:Extracellular vesicles (EVs), including exosomes, microvesicles, and apoptotic bodies, play an important role in cellular communication during skeletal growth and homeostasis. Bioactive molecules carried by EVs are transported to neighboring and distant cells to trigger a series of signaling cascades influencing bone ...

journal_title：Frontiers in physiology

authors： Yuan FL,Wu QY,Miao ZN,Xu MH,Xu RS,Jiang DL,Ye JX,Chen FH,Zhao MD,Wang HJ,Li X

更新日期：2018-05-30 00:00:00

abstract：:Cortical spreading depolarisation (CSD) is a transient disruption of ion balance that propagates along the cortex. It has been identified as an important factor in the progression of cerebral damage associated with stroke or traumatic brain injury. We analysed local field potential signals during CSD in old and young ...

journal_title：Frontiers in physiology

authors： Makra P,Menyhárt Á,Bari F,Farkas E

更新日期：2018-11-08 00:00:00

abstract：:Tree pandemics are a major cause of economic and ecological loss in forest and urban ecosystems. They often depend on the introduction of a non-native pathogen, which is occupying the niche of a native, non-aggressive organism. Complex interactions with native insects carrying fungi and nematodes can be established ba...

journal_title：Frontiers in physiology

authors： Santini A,Battisti A

更新日期：2019-05-08 00:00:00

abstract：:The main goal of this study was to assess the impact of the cambered bar (CB) during the bench press exercise on power output and bar velocity when compared to a standard bar (SB). Ten healthy strength-trained men (age = 27.9 ± 3.7 years; body mass = 90.1 ± 12.5 kg; resistance training experience = 6.5 ± 2.7 years; be...

journal_title：Frontiers in physiology

authors： Krzysztofik M,Zajac A,Żmijewski P,Wilk M

更新日期：2020-10-20 00:00:00

abstract：:The central purpose of this study was to evaluate the fiber type-specific satellite cell and myonuclear responses of endurance-trained cyclists to a block of intensified training, when supplementing with carbohydrate (CHO) vs. carbohydrate-protein (PRO). In a crossover design, endurance-trained cyclists (n = 8) perfor...

journal_title：Frontiers in physiology

authors： McKenzie AI,D'Lugos AC,Saunders MJ,Gworek KD,Luden ND

更新日期：2016-11-16 00:00:00