Xinnao Shutong Modulates the Neuronal Plasticity Through Regulation of Microglia/Macrophage Polarization Following Chronic Cerebral Hypoperfusion in Rats.

abstract：:Cardiovascular disease (CVD) continues to constitute the leading cause of death globally. CVD risk stratification is an essential tool to sort through heterogeneous populations and identify individuals at risk of developing CVD. However, applications of current risk scores have recently been shown to result in conside...

journal_title：Frontiers in physiology

authors： Björnson E,Borén J,Mardinoglu A

更新日期：2016-01-26 00:00:00

abstract：:Objective: This study aims to investigate the effect of astragaloside IV on adipose lipolysis and hepatic gluconeogenesis. Methods: High-fat diet (HFD) feeding induced adipose dysfunction with enhanced endogenous glucose production in mice. The effects of Astragaloside IV on lipolysis and hepatic glucose production we...

journal_title：Frontiers in physiology

authors： Du Q,Zhang S,Li A,Mohammad IS,Liu B,Li Y

更新日期：2018-01-23 00:00:00

abstract：:Muscle and tendon stiffness are related to sports performance, tendinopathy, and tendon degeneration. However, the effects of habitual loading on muscle and tendon mechanical properties are unclear. Using amateur basketball players as examples, we investigated the effects of mechanical loading on the stiffness of the ...

journal_title：Frontiers in physiology

authors： Chang TT,Li Z,Wang XQ,Zhang ZJ

更新日期：2020-12-10 00:00:00

abstract：:The mDurance® system is an innovative digital tool that combines wearable surface electromyography (sEMG), mobile computing and cloud analysis to streamline and automatize the assessment of muscle activity. The tool is particularly devised to support clinicians and sport professionals in their daily routines, as an as...

journal_title：Frontiers in physiology

authors： Molina-Molina A,Ruiz-Malagón EJ,Carrillo-Pérez F,Roche-Seruendo LE,Damas M,Banos O,García-Pinillos F

更新日期：2020-11-27 00:00:00

abstract：:Co-expressed genes often share similar functions, and gene co-expression networks have been widely used in studying the functionality of gene modules. Previous analysis indicated that genes are more likely to be co-expressed if they are either regulated by the same transcription factors, forming protein complexes or s...

journal_title：Frontiers in physiology

authors： Zhang C,Lee S,Mardinoglu A,Hua Q

更新日期：2016-05-02 00:00:00

abstract：:In recent years, time-varying inhomogeneous point process models have been introduced for assessment of instantaneous heartbeat dynamics as well as specific cardiovascular control mechanisms and hemodynamics. Assessment of the model's statistics is established through the Wiener-Volterra theory and a multivariate auto...

journal_title：Frontiers in physiology

authors： Chen Z,Purdon PL,Brown EN,Barbieri R

更新日期：2012-02-01 00:00:00

abstract：:Deep learning (DL) has attracted the attention of computational toxicologists as it offers a potentially greater power for in silico predictive toxicology than existing shallow learning algorithms. However, contradicting reports have been documented. To further explore the advantages of DL over shallow learning, we co...

journal_title：Frontiers in physiology

authors： Idakwo G,Thangapandian S,Luttrell J 4th,Zhou Z,Zhang C,Gong P

更新日期：2019-08-13 00:00:00

abstract：:Purpose: To provide insights into the energy requirements as well as the physiological adaptations of an experienced 50-year-old ultra-marathon male athlete during the world's most challenging mountain ultra-marathon (MUM). Methods: The international race supporting the study was the Tor des Geants®, characterized by ...

journal_title：Frontiers in physiology

authors： Savoldelli A,Fornasiero A,Trabucchi P,Limonta E,La Torre A,Degache F,Pellegrini B,Millet GP,Vernillo G,Schena F

更新日期：2017-12-05 00:00:00

abstract：BACKGROUND:During caesarean section spinal anesthesia may provoke maternal hypotension that we prevent by administration of phenylephrine and/or ephedrine. Phenylephrine is however reported to reduce the near infrared spectroscopy-determined frontal lobe oxygenation (ScO2) but whether that is the case for patients expo...

journal_title：Frontiers in physiology

authors： Foss VT,Christensen R,Rokamp KZ,Nissen P,Secher NH,Nielsen HB

更新日期：2014-03-03 00:00:00

abstract：:Electrical stimulation of the central and peripheral nervous systems - such as deep brain stimulation, spinal cord stimulation, and epidural cortical stimulation are common therapeutic options increasingly used to treat a large variety of neurological and psychiatric conditions. Despite their remarkable success, there...

journal_title：Frontiers in physiology

authors： Golestanirad L,Gale JT,Manzoor NF,Park HJ,Glait L,Haer F,Kaltenbach JA,Bonmassar G

更新日期：2018-07-27 00:00:00

abstract：:Rapamycin, also known as sirolimus, is an antifungal agent and immunosuppressant drug used to prevent organ rejection in transplantation. However, little is known about the role of rapamycin in cardiac hypertrophy and the signaling pathways involved. Here, the effect of rapamycin was examined using phenylephrine (PE) ...

journal_title：Frontiers in physiology

authors： Gu J,Hu W,Song ZP,Chen YG,Zhang DD,Wang CQ

更新日期：2016-03-18 00:00:00

abstract：:Aim: Acute ingestion of alcohol is often accompanied by cardiovascular dysregulation, malaise and even syncope. The full hemodynamic and cutaneous responses to the combination of alcohol and sugar (i.e., alcopops), a common combination in young people, and the mechanisms for the propensity to orthostatic intolerance a...

journal_title：Frontiers in physiology

authors： Maufrais C,Charriere N,Montani JP

更新日期：2017-11-10 00:00:00

abstract：:Astronauts exposed to microgravity face sensorimotor challenges affecting balance control when readapting to Earth's gravity upon return from spaceflight. Small amounts of electrical noise applied to the vestibular system have been shown to improve balance control during standing and walking under discordant sensory c...

journal_title：Frontiers in physiology

authors： Temple DR,De Dios YE,Layne CS,Bloomberg JJ,Mulavara AP

更新日期：2018-03-29 00:00:00

abstract：:Following partial hepatectomy, a coordinated series of molecular events occurs to regulate hepatocyte entry into the cell cycle to recover lost mass. In rats during the first 6 h following resection, hepatocytes are primed by a tightly controlled cytokine response to prepare hepatocytes to begin replication. Although ...

journal_title：Frontiers in physiology

authors： Cook DJ,Patra B,Kuttippurathu L,Hoek JB,Vadigepalli R

更新日期：2015-07-07 00:00:00

abstract：Purpose:This study aimed to evaluate effects of remote ischemic preconditioning (RIPC) on myocardial injury in patients undergoing off-pump coronary artery bypass graft surgery (OPCABG). Methods:Sixty-five patients scheduled for the OPCABG were randomly assigned to control (n = 32) or RIPC group (n = 33). All patients...

journal_title：Frontiers in physiology

authors： Wang H,Lyu Y,Liao Q,Jin L,Xu L,Hu Y,Yu Y,Guo K

更新日期：2019-04-29 00:00:00

abstract：:FXYD proteins are important regulators of Na+/K+-ATPase (NKA) activity in mammals. As an inhabitant of estuaries, the pufferfish (Tetraodon nigroviridis) responds to ambient salinity changes with efficient osmoregulation, including alterations in branchial, and renal NKA activities. Previous studies on teleostean FXYD...

journal_title：Frontiers in physiology

authors： Wang PJ,Yang WK,Lin CH,Hwang HH,Lee TH

更新日期：2017-08-08 00:00:00

abstract：:Previous research has quantified the peak movement demands of elite rugby league match-play, but the peak accelerometer load or the semi-professional peak demands remain unknown. The aim of this research was to determine the peak movement demands of professional and semi-professional rugby league competition. Wearable...

journal_title：Frontiers in physiology

authors： Johnston RD,Devlin P,Wade JA,Duthie GM

更新日期：2019-10-14 00:00:00

abstract：Objective:To explore the correlation between in vivo placental volumetric parameters in the first trimester of pregnancy and ex vivo parameters of fetoplacental vascular function after delivery. Methods:In ten singleton physiological pregnancies, placental volume (PV) and uteroplacental vascular volume (uPVV) were mea...

journal_title：Frontiers in physiology

authors： Hitzerd E,Reijnders IF,Mulders AGMGJ,Koning AHJ,Reiss IKM,Danser AHJ,Steegers-Theunissen RPM,Simons SHP,Koster MPH

更新日期：2020-01-24 00:00:00

abstract：:Eryptosis is the suicidal destruction-process of erythrocytes, much like apoptosis of nucleated cells, in the course of which the stressed red cell undergoes cell-shrinkage, vesiculation and externalization of membrane phosphatidylserine. Currently, there exist numerous methods to detect eryptosis, both morphometrical...

journal_title：Frontiers in physiology

authors： Jacob SS,Prasad K,Rao P,Kamath A,Hegde RB,Baby PM,Rao RK

更新日期：2019-09-24 00:00:00

abstract：:Increased central sympathetic drive is a hallmark of several important clinical conditions including essential hypertension, heart failure, chronic kidney disease, and insulin resistance. Afferent signaling from the kidneys has been identified as an important contributor to elevated central sympathetic drive and incre...

journal_title：Frontiers in physiology

authors： Schlaich MP,Hering D,Sobotka P,Krum H,Lambert GW,Lambert E,Esler MD

更新日期：2012-02-02 00:00:00

abstract：:Familial hypertrophic cardiomyopathy (HCM), due to point mutations in genes for sarcomere proteins such as myosin, occurs in 1/500 people and is the most common cause of sudden death in young individuals. Similar mutations in skeletal muscle, e.g., in the MYH7 gene for slow myosin found in both the cardiac ventricle a...

journal_title：Frontiers in physiology

authors： Månsson A

更新日期：2014-09-15 00:00:00

abstract：:Background: Skeletal muscle aging is marked by the development of a sarcopenic phenotype, a global decline of muscle energetic capacities, and an intolerance to exercise. Among the metabolic disorders involved in this syndrome, NAD metabolism was shown to be altered in skeletalmuscle, with an important role for the NA...

journal_title：Frontiers in physiology

authors： Deloux R,Tannous C,Ferry A,Li Z,Mericskay M

更新日期：2018-09-19 00:00:00

abstract：:The analysis of neural systems leverages tools from many different fields. Drawing on techniques from the study of critical phenomena in statistical mechanics, several studies have reported signatures of criticality in neural systems, including power-law distributions, shape collapses, and optimized quantities under t...

journal_title：Frontiers in physiology

authors： Timme NM,Marshall NJ,Bennett N,Ripp M,Lautzenhiser E,Beggs JM

更新日期：2016-09-27 00:00:00

abstract：:Drosophila melanogaster has served as an excellent genetic model to decipher the molecular basis of the circadian clock. Two key proteins, PERIOD (PER) and TIMELESS (TIM), are particularly well explored and a number of various arrhythmic, slow, and fast clock mutants have been identified in classical genetic screens. ...

journal_title：Frontiers in physiology

authors： Singh S,Giesecke A,Damulewicz M,Fexova S,Mazzotta GM,Stanewsky R,Dolezel D

更新日期：2019-12-03 00:00:00

abstract：:Purpose: This study aimed to examine the exercise-mediated musculoskeletal recovery following hindlimb suspension (HS) in order to identify whether bone modeling and muscle hypertrophy would eventuate in a synchronized manner during recovery stage. Methods: To identify whether 2-week HS would be sufficient to induce a...

journal_title：Frontiers in physiology

authors： Song H,Cho S,Lee HY,Lee H,Song W

更新日期：2018-08-13 00:00:00

abstract：:Different from other epithelia, the intestinal epithelium has the complex task of providing a barrier impeding the entry of toxins, food antigens, and microbes, while at the same time allowing for the transfer of nutrients, electrolytes, water, and microbial metabolites. These molecules/organisms are transported eithe...

journal_title：Frontiers in physiology

authors： Tang L,Cheng CY,Sun X,Pedicone AJ,Mohamadzadeh M,Cheng SX

更新日期：2016-06-21 00:00:00

abstract：OBJECTIVES:The dynamic interaction between blood pressure (BP) and cerebral blood flow velocity (CBFV) is not fully understood, especially for CBFV changes lasting longer than 50 s. The interaction between BP and CBFV is relatively well characterized for periods <50 s using transfer function (TF) estimations of phase, ...

journal_title：Frontiers in physiology

authors： Müller MW,Osterreich M

更新日期：2014-08-26 00:00:00

abstract：:As arteries become stiffer with aging, reflected waves move faster and augment late systolic pressure. Few studies have described the age-related changes in both peripheral and central systolic blood pressures in populations. We investigated the age dependency of peripheral (pSBP) and central (cSBP) systolic pressure ...

journal_title：Frontiers in physiology

authors： Wojciechowska W,Li Y,Stolarz-Skrzypek K,Kawecka-Jaszcz K,Staessen JA,Wang JG,European Project on Genes in Hypertension and the JingNing Study Investigators.

更新日期：2012-06-15 00:00:00

abstract：:Background: Non-invasive cardiac mapping-also known as Electrocardiographic imaging (ECGi)-is a novel, painless and relatively economic method to map the electrical activation and repolarization patterns of the heart, providing a valuable tool for early identification and diagnosis of conduction abnormalities and arrh...

journal_title：Frontiers in physiology

authors： Perez Alday EA,Whittaker DG,Benson AP,Colman MA

更新日期：2019-04-05 00:00:00

abstract：:Moonlighting proteins are a subset of multifunctional proteins characterized by their multiple, independent, and unrelated biological functions. We recently set up a large-scale identification of moonlighting proteins using a protein-protein interaction (PPI) network approach. We established that 3% of the current hum...

journal_title：Frontiers in physiology

authors： Zanzoni A,Chapple CE,Brun C

更新日期：2015-06-23 00:00:00