Abstract:
BACKGROUND:Dabigatran is a newly commercialized drug that is replacing other anticoagulants in the prevention of venous thromboembolism, stroke and systemic arterial valve embolism. It acts directly on thrombin presenting in a dynamic and predictable way, which does not require monitoring these patients. Therefore, we consider the need to assess whether their use increases the risk of bleeding involved before any dental treatment. MATERIAL AND METHODS:We performed a systematic review with a bibliographic search in PubMed/Medline along with the Cochrane Library. We excluded articles dealing with all anticoagulants other than dabigatran, and works about surgical treatments in anatomical locations other than the oral cavity. RESULTS:We included a total of 13 papers of which 1 was a randomized clinical trial, 9 narrative literature reviews, 1 case series, 2 clinical cases and 1 expert opinion. Because we did not obtain any properly designed clinical trials, we were unable to conduct a meta-analysis. CONCLUSIONS:Currently, there is no consensus on the procedure to be followed in patients taking dabigatran. However, all authors agree to treat each case individually in accordance to the risk of embolism, postoperative bleeding and renal function. Also, it is necessary to perform minimally invasive interventions, and take the appropriate local anti-hemolytic measures.
journal_name
Med Oral Patol Oral Cir Bucaljournal_title
Medicina oral, patologia oral y cirugia bucalauthors
Muñoz-Corcuera M,Ramírez-Martínez-Acitores L,López-Pintor RM,Casañas-Gil E,Hernández-Vallejo Gdoi
10.4317/medoral.21202subject
Has Abstractpub_date
2016-11-01 00:00:00pages
e679-e688issue
6eissn
1698-4447issn
1698-6946pii
21202journal_volume
21pub_type
杂志文章,评审abstract:OBJECTIVES:Patients with chronic graft-versus-host disease (cGVHD) often suffer from dry mouth and oral mucosal lesions. The primary objective of this study was to investigate the safety of an intra-oral electrostimulator (GenNarino) in symptomatic cGVHD patients. The secondary objective was to study the impact on the ...
journal_title:Medicina oral, patologia oral y cirugia bucal
pub_type: 杂志文章,随机对照试验
doi:10.4317/medoral.19429
更新日期:2014-05-01 00:00:00
abstract:OBJECTIVES:A study was made of the effect of nonsurgical periodontal treatment upon blood glucose control in type 2 diabetics with periodontal disease. STUDY DESIGN:A pre-post repeated measures analytical design was used, with a PubMed search of the related articles published up until December 2008. RESULTS:The impro...
journal_title:Medicina oral, patologia oral y cirugia bucal
pub_type: 杂志文章
doi:10.4317/medoral.15.e808
更新日期:2010-09-01 00:00:00
abstract:OBJECTIVE:To describe and discuss the design, building and usefulness of tissue microarray (TMA) blocks for the study of salivary gland tumors (SGTs). STUDY DESIGN:Two hundred thirty-eight formalin-fixed, paraffin-embedded SGTs were arranged in blocks of TMA using a manual tissue arrayer. Three representative cores of...
journal_title:Medicina oral, patologia oral y cirugia bucal
pub_type: 杂志文章
doi:10.4317/medoral.18204
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVE:To compare the long-term sealing ability of GuttaFlow® using different obturation techniques. STUDY DESIGN:Three hundred teeth, prepared with a crown-down technique, were divided into thirty experimental groups (n=10) to evaluate the apical and coronal leakage, at 3, 30 and 120 days, of lateral compaction gu...
journal_title:Medicina oral, patologia oral y cirugia bucal
pub_type: 杂志文章
doi:10.4317/medoral.15.e936
更新日期:2010-11-01 00:00:00
abstract:OBJECTIVE:The aim of this work was to assess the antifungal and post-antifungal effects of chlorhexidine, fluconazole, chitosan and its combinations on virulence factors of Candida albicans. STUDY DESIGN:Ten isolated strains of Candida albicans obtained from 10 patients with oral candidiasis and a collection strain of...
journal_title:Medicina oral, patologia oral y cirugia bucal
pub_type: 杂志文章
doi:10.4317/medoral.16.e23
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:The study of osteoblasts and their osteogenic functions is essential in order to understand them and their applications in implantology. In this sense, this study try to study BMP-2 production and bone matrix deposition, in addition to other biological variables, in osteoblasts cultured on a rough double aci...
journal_title:Medicina oral, patologia oral y cirugia bucal
pub_type: 杂志文章
doi:10.4317/medoral.22071
更新日期:2017-09-01 00:00:00
abstract::Sarcoidosis is a multisystemic granulomatous disease of unknown aetiology that usually presents with bilateral hiliar adenopathies, pulmonary infiltrations, and ocular and cutaneous lesions. The specific cutaneous lesions, or granulomatous, are produced in from 9% to 37% of patients with systemic sarcoidosis. Neverthe...
journal_title:Medicina oral, patologia oral y cirugia bucal
pub_type: 杂志文章
doi:
更新日期:2010-05-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to compare the effects in terms of resistance to fracture of the mandibular condyle and femoral head following different doses of zoledronic acid in an animal model. STUDY DESIGN:A total of 80 adult male Sprague-Dawley rats were included in a prospective randomized study. The animal...
journal_title:Medicina oral, patologia oral y cirugia bucal
pub_type: 杂志文章
doi:10.4317/medoral.18449
更新日期:2013-05-01 00:00:00
abstract:OBJECTIVES:Assessment of the oral health-related quality of life and the modulating factors of patients demanding dental treatment in the city of Salamanca, through the use of two validated instruments: the OIDP-sp (Oral Impacts on Daily Performance) and OHIP-14 (Oral Health Impact Profile). STUDY DESIGN:the study was...
journal_title:Medicina oral, patologia oral y cirugia bucal
pub_type: 杂志文章
doi:10.4317/medoral.16790
更新日期:2011-09-01 00:00:00
abstract:OBJECTIVE:To assess the microbiological effects of an antiseptic, non-alcohol based mouth-rinse containing chlorhexidine and cetylpyridinium chloride, in patients undergoing radiation therapy for head-and-neck cancer. STUDY DESIGN:This was a parallel, double-blind, prospective, randomized clinical trial, including pat...
journal_title:Medicina oral, patologia oral y cirugia bucal
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2011-11-01 00:00:00
abstract::The odontogenic myxoma is a rare entity located in mandible and upper maxilla. Due to its local aggressiveness, wide surgical excision is mandatory. Several surgical techniques have been described for the reconstruction of segmental mandibular defects. In comparison with other free flaps, the vascularized free fibular...
journal_title:Medicina oral, patologia oral y cirugia bucal
pub_type: 杂志文章
doi:
更新日期:2006-11-01 00:00:00
abstract:BACKGROUND:Oral Graft-versus-Host Disease (oGvHD) is a common complication of haematopoietic stem cell transplantation. Choosing the right topical application to be used intra orally can be a challenge. Consequently, the aim of this work is to review the effectiveness and safety of topical agents currently used in the ...
journal_title:Medicina oral, patologia oral y cirugia bucal
pub_type: 杂志文章,评审
doi:10.4317/medoral.20968
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Cheilitis granulomatosa (CG) is a disturbing and persistent idiopathic lip swelling. The cause and treatment has not been wholly elucidated. Some reports infer that CG is mainly associated with dental infection but no firm or reliable microbiological evidence has been provided for a causative organism. This ...
journal_title:Medicina oral, patologia oral y cirugia bucal
pub_type: 杂志文章
doi:10.4317/medoral.23041
更新日期:2019-11-01 00:00:00
abstract:AIM:To assess the prevalence of oral mucosa lesions (OL) in a group of kidney transplant (KT) patients, and analyze possible OL associations with one another and with drugs use and relevant clinical and laboratory variables. METHODOLOGY:Transversal study, in which consecutive KT patients from the nephrology outpatient...
journal_title:Medicina oral, patologia oral y cirugia bucal
pub_type: 杂志文章
doi:
更新日期:2005-05-01 00:00:00
abstract:BACKGROUND:Oral ulcers caused by methotrexate (MTX) at low doses are a known side effect of this drug. Although increasingly more patients are medicated with MTX, these painful ulcers, without traumatic origin and resistant to any type of treatment, are not usually identified by health professionals as a side effect of...
journal_title:Medicina oral, patologia oral y cirugia bucal
pub_type: 杂志文章
doi:10.4317/medoral.22851
更新日期:2019-03-01 00:00:00
abstract:STATEMENT OF PROBLEM:One of the main problems posed by complete dentures is retention and stability. In order to solve this problem, dentists and the dental industry for a long time have attempted to improve denture adhesion by developing a range of "glues" of highly varied composition and efficacy. PURPOSE:The presen...
journal_title:Medicina oral, patologia oral y cirugia bucal
pub_type: 临床试验,杂志文章
doi:10.4317/medoral.16.e132
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVES:Some ameloblastomas presumably originate from odontogenic epithelium within the connective tissue of dental follicles and dentigerous cysts. Therefore, it would seem reasonable to discuss as whether odontogenic epithelium proliferations, frankly displaying ameloblastomatous features ("focal ameloblastoma"), ...
journal_title:Medicina oral, patologia oral y cirugia bucal
pub_type: 杂志文章
doi:10.4317/medoral.18372
更新日期:2013-01-01 00:00:00
abstract:INTRODUCTION:As important effector cells of the innate immune system, neutrophils are involved in rejection of solid organ and/or tissue transplants. But their role in rejection of oral mucosa transplantation (OMT) remains unclear. The aim of this study is to observe the spatial-temporal change of neutrophils during ac...
journal_title:Medicina oral, patologia oral y cirugia bucal
pub_type: 杂志文章
doi:10.4317/medoral.16.e341
更新日期:2011-05-01 00:00:00
abstract:BACKGROUND:Among the oral potentially malignant disorders, leukoplakia stands out as the most prevalent. The purpose of this study was to analyse the clinical-pathological features of oral leukoplakia in groups of patients from three major pathology centers in two different regions of Brazil, in order to determine whic...
journal_title:Medicina oral, patologia oral y cirugia bucal
pub_type: 杂志文章
doi:10.4317/medoral.24175
更新日期:2020-11-28 00:00:00
abstract:BACKGROUND:Was to describe 14 cases of a proliferative verrucous leukoplakia as a clinical evolution of oral lichen planus. MATERIAL AND METHODS:The clinical and histopathological characteristics of 14 cases of OLP that progress towards a plaque-like and verrucous form were indicated, with monitoring over a period of ...
journal_title:Medicina oral, patologia oral y cirugia bucal
pub_type: 杂志文章
doi:10.4317/medoral.20832
更新日期:2016-05-01 00:00:00
abstract:BACKGROUND:Non-surgical treatment has generally been recommended for stage II medication-related osteonecrosis of the jaw (MRONJ) in preference to surgery. However, non-surgical treatment is not empirically effective. The aim of this study was to evaluate whether surgical or non-surgical treatment leads to better outco...
journal_title:Medicina oral, patologia oral y cirugia bucal
pub_type: 杂志文章
doi:10.4317/medoral.22013
更新日期:2017-11-01 00:00:00
abstract::Burning mouth syndrome (BMS) refers to chronic orofacial pain, unaccompanied by mucosal lesions or other evident clinical signs. It is observed principally in middle-aged patients and postmenopausal women. BMS is characterized by an intense burning or stinging sensation, preferably on the tongue or in other areas of t...
journal_title:Medicina oral, patologia oral y cirugia bucal
pub_type: 杂志文章,评审
doi:10.4317/medoral.15.e562
更新日期:2010-07-01 00:00:00
abstract:OBJECTIVES:To determine whether there is a relationship between the total BP dose administered and the variations in serum CTX concentration. STUDY DESIGN:The study included 50 patients requiring dental implant surgery and treated with oral BPs, seen in an Oral Surgery and Implantology Unit between January 2007 and Ju...
journal_title:Medicina oral, patologia oral y cirugia bucal
pub_type: 杂志文章
doi:10.4317/medoral.17583
更新日期:2012-05-01 00:00:00
abstract:BACKGROUND:To elucidate the significance of absorbable surgical sutures in the occurrence of stitch abscess after surgery in patients with oral squamous cell carcinoma (SCC). MATERIAL AND METHODS:The subjects were 251 patients who underwent excision and/or reconstruction and/or neck dissection for oral SCC using absor...
journal_title:Medicina oral, patologia oral y cirugia bucal
pub_type: 杂志文章
doi:10.4317/medoral.21445
更新日期:2017-05-01 00:00:00
abstract::Tooth agenesis is one of the most common congenital malformations in humans. Hypodontia can either occur as an isolated condition (non-syndromic hypodontia) or can be associated with a syndrome (syndromic hypodontia), highlighting the heterogeneity of the condition. Though much progress has been made to identify the d...
journal_title:Medicina oral, patologia oral y cirugia bucal
pub_type: 杂志文章,评审
doi:10.4317/medoral.19158
更新日期:2014-03-01 00:00:00
abstract::The appearance of a solitary lateral cervical cystic mass as the only initial presenting symptom of occult thyroid carcinoma is uncommon. Its presence is often misdiagnosed due to the more frequent branchial cyst in young people. Although oronasopharyngeal squamous cell carcinoma has been reported as the main cause of...
journal_title:Medicina oral, patologia oral y cirugia bucal
pub_type: 杂志文章
doi:
更新日期:2008-12-01 00:00:00
abstract:OBJECTIVE:Until recently, most reports about transmigration have documented that the canine is the only tooth which can migrate to the opposite side of the arch. The goal of the study was to define the transmigration of different types of teeth in people in various regions of Turkey. STUDY DESIGN:A total of 112,873 pa...
journal_title:Medicina oral, patologia oral y cirugia bucal
pub_type: 杂志文章
doi:10.4317/medoral.16.e335
更新日期:2011-05-01 00:00:00
abstract:INTRODUCTION:Frey's Syndrome is defined by facial hyperhidrosis in the preauricular region unleashed by gustatory stimulus and caused mainly by parotidectomy. Several treatment and prevention measures have been proposed, with no conclusive results. Recently, injections of Botulinum Toxin have been suggested, obtaining ...
journal_title:Medicina oral, patologia oral y cirugia bucal
pub_type: 杂志文章
doi:
更新日期:2008-04-01 00:00:00
abstract:OBJECTIVE:This article presents the results of a retrospective study of the frequency and classification of odontogenic tumors recorded at four centers of diagnostic pathology in Rio de Janeiro, Brazil. STUDY DESIGN:All medical records and microscopic slides of odontogenic tumor specimens for the years 1997 to 2007 we...
journal_title:Medicina oral, patologia oral y cirugia bucal
pub_type: 杂志文章,多中心研究
doi:10.4317/medoral.17630
更新日期:2012-05-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate the presence of human papillomavirus (HPV) in saliva rinses of patients with oral squamous cell carcinoma and to analyze the possibility of using saliva as a diagnostic method for screening high-risk patients. STUDY DESIGN:The saliva sample of 22 patients with oral squam...
journal_title:Medicina oral, patologia oral y cirugia bucal
pub_type: 杂志文章
doi:10.4317/medoral.14.e525
更新日期:2009-10-01 00:00:00